-
1
-
-
0029026638
-
Structure and function of voltage-gated ion channels
-
Catterall WA Structure and function of voltage-gated ion channels. Annu Rev Biochem 1995 64 493 531.
-
(1995)
Annu Rev Biochem
, vol.64
, pp. 493-531
-
-
Catterall, W.A.1
-
2
-
-
0030156610
-
Ion channels in plasma membrane signal transduction
-
Catterall WA Ion channels in plasma membrane signal transduction. J Bioenerg Biomembr 1996 28 217 218.
-
(1996)
J Bioenerg Biomembr
, vol.28
, pp. 217-218
-
-
Catterall, W.A.1
-
4
-
-
0033694833
-
From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels
-
Catterall WA From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron 2000 26 13 25.
-
(2000)
Neuron
, vol.26
, pp. 13-25
-
-
Catterall, W.A.1
-
5
-
-
0024368695
-
Structural parts involved in activation and inactivation of the sodium channel
-
Stuhmer W Conti F Suzuki H Wang XD Noda M Yahagi N Kubo H Numa S Structural parts involved in activation and inactivation of the sodium channel. Nature 1989 339 597 603.
-
(1989)
Nature
, vol.339
, pp. 597-603
-
-
Stuhmer, W.1
Conti, F.2
Suzuki, H.3
Wang, X.D.4
Noda, M.5
Yahagi, N.6
Kubo, H.7
Numa, S.8
-
6
-
-
0026439086
-
Amino acid residues required for fast Na(+)-channel inactivation: Charge neutralizations and deletions in the III-IV linker
-
Patton DE West JW Catterall WA Goldin AL Amino acid residues required for fast Na(+)-channel inactivation: Charge neutralizations and deletions in the III-IV linker. Proc Natl Acad Sci USA 1992 89 10905 10909.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10905-10909
-
-
Patton, D.E.1
West, J.W.2
Catterall, W.A.3
Goldin, A.L.4
-
9
-
-
0029044707
-
A critical role for transmembrane segment IVS6 of the sodium channel alpha subunit in fast inactivation
-
McPhee JC Ragsdale DS Scheuer T Catterall WA A critical role for transmembrane segment IVS6 of the sodium channel alpha subunit in fast inactivation. J Biol Chem 1995 270 12025 12034.
-
(1995)
J Biol Chem
, vol.270
, pp. 12025-12034
-
-
McPhee, J.C.1
Ragsdale, D.S.2
Scheuer, T.3
Catterall, W.A.4
-
10
-
-
0030908111
-
Molecular analysis of potential hinge residues in the inactivation gate of brain type IIA Na+ channels
-
Kellenberger S West JW Catterall WA Scheuer T Molecular analysis of potential hinge residues in the inactivation gate of brain type IIA Na+ channels. J Gen Physiol 1997 109 607 617.
-
(1997)
J Gen Physiol
, vol.109
, pp. 607-617
-
-
Kellenberger, S.1
West, J.W.2
Catterall, W.A.3
Scheuer, T.4
-
11
-
-
0030920792
-
Molecular analysis of the putative inactivation particle in the inactivation gate of brain type IIA Na+ channels
-
Kellenberger S West JW Scheuer T Catterall WA Molecular analysis of the putative inactivation particle in the inactivation gate of brain type IIA Na+ channels. J Gen Physiol 1997 109 589 605.
-
(1997)
J Gen Physiol
, vol.109
, pp. 589-605
-
-
Kellenberger, S.1
West, J.W.2
Scheuer, T.3
Catterall, W.A.4
-
12
-
-
0031975208
-
A critical role for the S4-S5 intracellular loop in domain IV of the sodium channel alpha-subunit in fast inactivation
-
McPhee JC Ragsdale DS Scheuer T Catterall WA A critical role for the S4-S5 intracellular loop in domain IV of the sodium channel alpha-subunit in fast inactivation. J Biol Chem 1998 273 1121 1129.
-
(1998)
J Biol Chem
, vol.273
, pp. 1121-1129
-
-
McPhee, J.C.1
Ragsdale, D.S.2
Scheuer, T.3
Catterall, W.A.4
-
13
-
-
0035936798
-
Molecular and cellular mechanisms of cardiac arrhythmias
-
Keating MT Sanguinetti MC Molecular and cellular mechanisms of cardiac arrhythmias. Cell 2001 104 569 580.
-
(2001)
Cell
, vol.104
, pp. 569-580
-
-
Keating, M.T.1
Sanguinetti, M.C.2
-
14
-
-
12844272885
-
Inherited and acquired vulnerability to ventricular arrhythmias: Cardiac Na+ and K+ channels
-
Clancy CE Kass RS Inherited and acquired vulnerability to ventricular arrhythmias: Cardiac Na+ and K+ channels. Physiol Rev 2005 85 33 47.
-
(2005)
Physiol Rev
, vol.85
, pp. 33-47
-
-
Clancy, C.E.1
Kass, R.S.2
-
16
-
-
0021086246
-
A reinterpretation of mammalian sodium channel gating based on single channel recording
-
Aldrich RW Corey DP Stevens CF A reinterpretation of mammalian sodium channel gating based on single channel recording. Nature 1983 306 436 441.
-
(1983)
Nature
, vol.306
, pp. 436-441
-
-
Aldrich, R.W.1
Corey, D.P.2
Stevens, C.F.3
-
17
-
-
0029846880
-
Movement of the Na+ channel inactivation gate during inactivation
-
996
-
Kellenberger S Scheuer T Catterall WA Movement of the Na+ channel inactivation gate during inactivation. J Biol Chem 996 271 30971 30979.
-
J Biol Chem
, vol.271
, pp. 30971-30979
-
-
Kellenberger, S.1
Scheuer, T.2
Catterall, W.A.3
-
18
-
-
0345211487
-
Cysteine scanning analysis of the IFM cluster in the inactivation gate of a human heart sodium channel
-
Deschenes I Trottier E Chahine M Cysteine scanning analysis of the IFM cluster in the inactivation gate of a human heart sodium channel. Cardiovasc Res 1999 42 521 529.
-
(1999)
Cardiovasc Res
, vol.42
, pp. 521-529
-
-
Deschenes, I.1
Trottier, E.2
Chahine, M.3
-
19
-
-
0034116131
-
The role of the putative inactivation lid in sodium channel gating current immobilization
-
Sheets MF Kyle JW Hanck DA The role of the putative inactivation lid in sodium channel gating current immobilization. J Gen Physiol 2000 115 609 620.
-
(2000)
J Gen Physiol
, vol.115
, pp. 609-620
-
-
Sheets, M.F.1
Kyle, J.W.2
Hanck, D.A.3
-
20
-
-
0029814358
-
Role of an S4-S5 linker in sodium channel inactivation probed by mutagenesis and a peptide blocker
-
Tang L Kallen RG Horn R Role of an S4-S5 linker in sodium channel inactivation probed by mutagenesis and a peptide blocker. J Gen Physiol 1996 108 89 104.
-
(1996)
J Gen Physiol
, vol.108
, pp. 89-104
-
-
Tang, L.1
Kallen, R.G.2
Horn, R.3
-
22
-
-
0032819357
-
Structural determinants of slow inactivation in human cardiac and skeletal muscle sodium channels
-
Vilin YY Makita N George AL Jr. Structural determinants of slow inactivation in human cardiac and skeletal muscle sodium channels. Biophys J 1999 77 1384 1393.
-
(1999)
Biophys J
, vol.77
, pp. 1384-1393
-
-
Vilin, Y.Y.1
Makita, N.2
George Jr., A.L.3
-
23
-
-
0026517122
-
Calcium channel characteristics conferred on the sodium channel by single mutations
-
Heinemann SH Terlau H Stuhmer W Imoto K Numa S Calcium channel characteristics conferred on the sodium channel by single mutations. Nature 1992 356 441 443.
-
(1992)
Nature
, vol.356
, pp. 441-443
-
-
Heinemann, S.H.1
Terlau, H.2
Stuhmer, W.3
Imoto, K.4
Numa, S.5
-
25
-
-
0019229706
-
Sodium channel permeation in squid axons. II: Non-independence and current-voltage relations
-
Begenisich TB Cahalan MD Sodium channel permeation in squid axons. II: Non-independence and current-voltage relations. J Physiol 1980 307 243 257.
-
(1980)
J Physiol
, vol.307
, pp. 243-257
-
-
Begenisich, T.B.1
Cahalan, M.D.2
-
26
-
-
0028353825
-
Ion permeation, divalent ion block, and chemical modification of single sodium channels. Description by single- and double-occupancy rate-theory models
-
French RJ Worley JF 3rd. Wonderlin WF Kularatna AS Krueger BK Ion permeation, divalent ion block, and chemical modification of single sodium channels. Description by single- and double-occupancy rate-theory models. J Gen Physiol 1994 103 447 470.
-
(1994)
J Gen Physiol
, vol.103
, pp. 447-470
-
-
French, R.J.1
Worley III, J.F.2
Wonderlin, W.F.3
Kularatna, A.S.4
Krueger, B.K.5
-
27
-
-
0027340610
-
Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels
-
Yang J Ellinor PT Sather WA Zhang JF Tsien RW Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels. Nature 1993 366 158 161.
-
(1993)
Nature
, vol.366
, pp. 158-161
-
-
Yang, J.1
Ellinor, P.T.2
Sather, W.A.3
Zhang, J.F.4
Tsien, R.W.5
-
28
-
-
0028233952
-
Structural basis of ion channel permeation and selectivity
-
Sather WA Yang J Tsien RW Structural basis of ion channel permeation and selectivity. Curr Opin Neurobiol 1994 4 313 323.
-
(1994)
Curr Opin Neurobiol
, vol.4
, pp. 313-323
-
-
Sather, W.A.1
Yang, J.2
Tsien, R.W.3
-
29
-
-
0028927960
-
A mutation in the pore of the sodium channel alters gating
-
Tomaselli GF Chiamvimonvat N Nuss HB Balser JR Perez-Garcia MT Xu RH Orias DW Backx PH Marban E A mutation in the pore of the sodium channel alters gating. Biophys J 1995 68 1814 1827.
-
(1995)
Biophys J
, vol.68
, pp. 1814-1827
-
-
Tomaselli, G.F.1
Chiamvimonvat, N.2
Nuss, H.B.3
Balser, J.R.4
Perez-Garcia, M.T.5
Xu, R.H.6
Orias, D.W.7
Backx, P.H.8
Marban, E.9
-
30
-
-
0035958956
-
The selectivity filter of the voltage-gated sodium channel is involved in channel activation
-
Hilber K Sandtner W Kudlacek O Glaaser IW Weisz E Kyle JW French RJ Fozzard HA Dudley SC Todt H The selectivity filter of the voltage-gated sodium channel is involved in channel activation. J Biol Chem 2001 276 27831 27839.
-
(2001)
J Biol Chem
, vol.276
, pp. 27831-27839
-
-
Hilber, K.1
Sandtner, W.2
Kudlacek, O.3
Glaaser, I.W.4
Weisz, E.5
Kyle, J.W.6
French, R.J.7
Fozzard, H.A.8
Dudley, S.C.9
Todt, H.10
-
31
-
-
3142695485
-
Block of tetrodotoxin-resistant Na+ channel pore by multivalent cations: Gating modification and Na+ flow dependence
-
Kuo CC Chen WY Yang YC Block of tetrodotoxin-resistant Na+ channel pore by multivalent cations: Gating modification and Na+ flow dependence. J Gen Physiol 2004 124 27 42.
-
(2004)
J Gen Physiol
, vol.124
, pp. 27-42
-
-
Kuo, C.C.1
Chen, W.Y.2
Yang, Y.C.3
-
32
-
-
0029990996
-
Dynamic rearrangement of the outer mouth of a K+ channel during gating
-
Liu Y Jurman ME Yellen G Dynamic rearrangement of the outer mouth of a K+ channel during gating. Neuron 1996 16 859 867.
-
(1996)
Neuron
, vol.16
, pp. 859-867
-
-
Liu, Y.1
Jurman, M.E.2
Yellen, G.3
-
33
-
-
0036801431
-
Defective cardiac ion channels: From mutations to clinical syndromes
-
Clancy CE Kass RS Defective cardiac ion channels: From mutations to clinical syndromes. J Clin Invest 2002 110 1075 1077.
-
(2002)
J Clin Invest
, vol.110
, pp. 1075-1077
-
-
Clancy, C.E.1
Kass, R.S.2
-
34
-
-
0036839970
-
Insights into the molecular mechanisms of bradycardia-triggered arrhythmias in long QT-3 syndrome
-
Clancy CE Tateyama M Kass RS Insights into the molecular mechanisms of bradycardia-triggered arrhythmias in long QT-3 syndrome. J Clin Invest 2002 110 1251 1262.
-
(2002)
J Clin Invest
, vol.110
, pp. 1251-1262
-
-
Clancy, C.E.1
Tateyama, M.2
Kass, R.S.3
-
35
-
-
0033527032
-
Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia
-
Clancy CE Rudy Y Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia. Nature 1999 400 566 569.
-
(1999)
Nature
, vol.400
, pp. 566-569
-
-
Clancy, C.E.1
Rudy, Y.2
-
36
-
-
0034800266
-
Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome
-
Nuyens D Stengl M Dugarmaa S Rossenbacker T Compernolle V Rudy Y Smits JF Flameng W Clancy CE Moons L Vos MA Dewerchin M Benndorf K Collen D Carmeliet E Carmeliet P Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome. Nat Med 2001 7 1021 1027.
-
(2001)
Nat Med
, vol.7
, pp. 1021-1027
-
-
Nuyens, D.1
Stengl, M.2
Dugarmaa, S.3
Rossenbacker, T.4
Compernolle, V.5
Rudy, Y.6
Smits, J.F.7
Flameng, W.8
Clancy, C.E.9
Moons, L.10
Vos, M.A.11
Dewerchin, M.12
Benndorf, K.13
Collen, D.14
Carmeliet, E.15
Carmeliet, P.16
-
37
-
-
0028243530
-
Gating of cardiac Na+ channels in excised membrane patches after modification by alpha-chymotrypsin
-
Valenzuela C Bennett PB Jr. Gating of cardiac Na+ channels in excised membrane patches after modification by alpha-chymotrypsin. Biophys J 1994 67 161 171.
-
(1994)
Biophys J
, vol.67
, pp. 161-171
-
-
Valenzuela, C.1
Bennett Jr., P.B.2
-
39
-
-
0037066036
-
Na(+) channel mutation that causes both Brugada and long-QT syndrome phenotypes: A simulation study of mechanism
-
Clancy CE Rudy Y Na(+) channel mutation that causes both Brugada and long-QT syndrome phenotypes: A simulation study of mechanism. Circulation 2002 105 1208 1213.
-
(2002)
Circulation
, vol.105
, pp. 1208-1213
-
-
Clancy, C.E.1
Rudy, Y.2
-
40
-
-
0037015190
-
A novel SCN5A mutation associated with long QT-3: Altered inactivation kinetics and channel dysfunction
-
Rivolta I Clancy CE Tateyama M Liu H Priori SG Kass RS A novel SCN5A mutation associated with long QT-3: Altered inactivation kinetics and channel dysfunction. Physiol Genomics 2002 10 191 197.
-
(2002)
Physiol Genomics
, vol.10
, pp. 191-197
-
-
Rivolta, I.1
Clancy, C.E.2
Tateyama, M.3
Liu, H.4
Priori, S.G.5
Kass, R.S.6
-
41
-
-
0033594970
-
Congenital long-QT syndrome caused by a novel mutation in a conserved acidic domain of the cardiac Na+ channel
-
Wei J Wang DW Alings M et al Congenital long-QT syndrome caused by a novel mutation in a conserved acidic domain of the cardiac Na+ channel. Circulation 1999 99 3165 3171.
-
(1999)
Circulation
, vol.99
, pp. 3165-3171
-
-
Wei, J.1
Wang, D.W.2
Alings, M.3
Al, E.4
-
42
-
-
0034731314
-
Biophysical phenotypes of SCN5A mutations causing long QT and Brugada syndromes
-
Baroudi G Chahine M Biophysical phenotypes of SCN5A mutations causing long QT and Brugada syndromes. FEBS Lett 2000 487 224 228.
-
(2000)
FEBS Lett
, vol.487
, pp. 224-228
-
-
Baroudi, G.1
Chahine, M.2
-
44
-
-
0037088663
-
Secondary structure of the human cardiac Na+ channel C terminus: Evidence for a role of helical structures in modulation of channel inactivation
-
Cormier JW Rivolta I Tateyama M Yang AS Kass RS Secondary structure of the human cardiac Na+ channel C terminus: Evidence for a role of helical structures in modulation of channel inactivation. J Biol Chem 2002 277 9233 9241.
-
(2002)
J Biol Chem
, vol.277
, pp. 9233-9241
-
-
Cormier, J.W.1
Rivolta, I.2
Tateyama, M.3
Yang, A.S.4
Kass, R.S.5
-
45
-
-
4043059200
-
Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination
-
van Bemmelen MX Rougier JS Gavillet B Apotheloz F Daidie D Tateyama M Rivolta I Thomas MA Kass RS Staub O Abriel H Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination. Circ Res 2004 95 284 291.
-
(2004)
Circ Res
, vol.95
, pp. 284-291
-
-
Van Bemmelen, M.X.1
Rougier, J.S.2
Gavillet, B.3
Apotheloz, F.4
Daidie, D.5
Tateyama, M.6
Rivolta, I.7
Thomas, M.A.8
Kass, R.S.9
Staub, O.10
Abriel, H.11
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