Structures of the Human HCN1 Hyperpolarization-Activated Channel

Cell

Volumn 168, Issue 1-2, 2017, Pages 111-120.e11

  Lee, Chia Hsueh ^a   MacKinnon, Roderick ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

atomic structure; cardiac and neuronal pacemaker; cryo electron microscopy; hyperpolarization activated ion channel; ion selectivity; rhythmic firing; voltage dependent gating

Indexed keywords

CYCLIC AMP; CYCLIC NUCLEOTIDE; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL; POTASSIUM CHANNEL; POTASSIUM ION; PROTEIN HCN1; SODIUM CHANNEL; SODIUM ION; UNCLASSIFIED DRUG; HCN1 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; CYTOPLASM; ELECTROPHYSIOLOGICAL PROCEDURES; FEMALE; HUMAN; ION PERMEABILITY; MOLECULAR SENSOR; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR MODEL; PROCEDURES; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; CRYOELECTRON MICROSCOPY; CYCLIC AMP; HUMANS; HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS; MODELS, MOLECULAR; POTASSIUM CHANNELS; SEQUENCE ALIGNMENT;

EID: 85009210607     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.12.023     Document Type: Article

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