-
1
-
-
0028277886
-
Development of the anti-gp120 antibody response during seroconversion to human immunodeficiency virus type 1
-
Moore JP, Cao Y, Ho DD, Koup RA. Development of the anti-gp120 antibody response during seroconversion to human immunodeficiency virus type 1. J Virol (1994) 68(8):5142-55.
-
(1994)
J Virol
, vol.68
, Issue.8
, pp. 5142-5155
-
-
Moore, J.P.1
Cao, Y.2
Ho, D.D.3
Koup, R.A.4
-
2
-
-
33144486096
-
Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1
-
Moore PL, Crooks ET, Porter L, Zhu P, Cayanan CS, Grise H, et al. Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1. J Virol (2006) 80(5):2515-28. doi: 10.1128/JVI.80.5.2515-2528.2006.
-
(2006)
J Virol
, vol.80
, Issue.5
, pp. 2515-2528
-
-
Moore, P.L.1
Crooks, E.T.2
Porter, L.3
Zhu, P.4
Cayanan, C.S.5
Grise, H.6
-
3
-
-
0036435095
-
Sustained antibody-dependent cell-mediated cytotoxicity (ADCC) in SIV-infected macaques correlates with delayed progression to AIDS
-
Banks ND, Kinsey N, Clements J, Hildreth JE. Sustained antibody-dependent cell-mediated cytotoxicity (ADCC) in SIV-infected macaques correlates with delayed progression to AIDS. AIDS Res Hum Retroviruses (2002) 18(16):1197-205. doi:10.1089/08892220260387940.
-
(2002)
AIDS Res Hum Retroviruses
, vol.18
, Issue.16
, pp. 1197-1205
-
-
Banks, N.D.1
Kinsey, N.2
Clements, J.3
Hildreth, J.E.4
-
4
-
-
0034958413
-
Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural-killer effector cells
-
Forthal DN, Landucci G, Daar ES. Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural-killer effector cells. J Virol (2001) 75(15):6953-61. doi:10.1128/JVI.75.15.6953-6961.2001.
-
(2001)
J Virol
, vol.75
, Issue.15
, pp. 6953-6961
-
-
Forthal, D.N.1
Landucci, G.2
Daar, E.S.3
-
5
-
-
0033375327
-
Antibody-dependent cellular cytotoxicity independently predicts survival in severely immunocompromised human immunodeficiency virus-infected patients
-
Forthal DN, Landucci G, Haubrich R, Keenan B, Kuppermann BD, Tilles JG, et al. Antibody-dependent cellular cytotoxicity independently predicts survival in severely immunocompromised human immunodeficiency virus-infected patients. J Infect Dis (1999) 180(4):1338-41. doi:10.1086/314988.
-
(1999)
J Infect Dis
, vol.180
, Issue.4
, pp. 1338-1341
-
-
Forthal, D.N.1
Landucci, G.2
Haubrich, R.3
Keenan, B.4
Kuppermann, B.D.5
Tilles, J.G.6
-
6
-
-
13544277161
-
Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251
-
Gómez-Román VR, Patterson LJ, Venzon D, Liewehr D, Aldrich K, Florese R, et al. Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251. J Immunol (2005) 174(4):2185-9. doi:10.4049/jimmunol.174.4.2185.
-
(2005)
J Immunol
, vol.174
, Issue.4
, pp. 2185-2189
-
-
Gómez-Román, V.R.1
Patterson, L.J.2
Venzon, D.3
Liewehr, D.4
Aldrich, K.5
Florese, R.6
-
7
-
-
33744916994
-
Nonneutralizing antibodies are able to inhibit human immunodeficiency virus type 1 replication in macrophages and immature dendritic cells
-
Holl V, Peressin M, Decoville T, Schmidt S, Zolla-Pazner S, Aubertin AM, et al. Nonneutralizing antibodies are able to inhibit human immunodeficiency virus type 1 replication in macrophages and immature dendritic cells. J Virol (2006) 80(12):6177-81. doi:10.1128/JVI.02625-05.
-
(2006)
J Virol
, vol.80
, Issue.12
, pp. 6177-6181
-
-
Holl, V.1
Peressin, M.2
Decoville, T.3
Schmidt, S.4
Zolla-Pazner, S.5
Aubertin, A.M.6
-
8
-
-
0030897825
-
Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex
-
Fouts TR, Binley JM, Trkola A, Robinson JE, Moore JP. Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex. J Virol (1997) 71(4):2779-85.
-
(1997)
J Virol
, vol.71
, Issue.4
, pp. 2779-2785
-
-
Fouts, T.R.1
Binley, J.M.2
Trkola, A.3
Robinson, J.E.4
Moore, J.P.5
-
9
-
-
0025362335
-
Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees
-
Nara PL, Smit L, Dunlop N, Hatch W, Merges M, Waters D, et al. Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees. J Virol (1990) 64(8):3779-91.
-
(1990)
J Virol
, vol.64
, Issue.8
, pp. 3779-3791
-
-
Nara, P.L.1
Smit, L.2
Dunlop, N.3
Hatch, W.4
Merges, M.5
Waters, D.6
-
10
-
-
0037389643
-
Rapid evolution of the neutralizing antibody response to HIV type 1 infection
-
Richman DD, Wrin T, Little SJ, Petropoulos CJ. Rapid evolution of the neutralizing antibody response to HIV type 1 infection. Proc Natl Acad Sci U S A (2003) 100(7):4144-9. doi:10.1073/pnas.0630530100.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.7
, pp. 4144-4149
-
-
Richman, D.D.1
Wrin, T.2
Little, S.J.3
Petropoulos, C.J.4
-
11
-
-
56449131391
-
Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C
-
Binley JM, Lybarger EA, Crooks ET, Seaman MS, Gray E, Davis KL, et al. Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C. J Virol (2008) 82(23):11651-68. doi:10.1128/JVI.01762-08.
-
(2008)
J Virol
, vol.82
, Issue.23
, pp. 11651-11668
-
-
Binley, J.M.1
Lybarger, E.A.2
Crooks, E.T.3
Seaman, M.S.4
Gray, E.5
Davis, K.L.6
-
12
-
-
27244460793
-
Antibody vs. HIV in a clash of evolutionary titans
-
Burton DR, Stanfield RL, Wilson IA. Antibody vs. HIV in a clash of evolutionary titans. Proc Natl Acad Sci U S A (2005) 102(42):14943-8. doi:10.1073/pnas.0505126102.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.42
, pp. 14943-14948
-
-
Burton, D.R.1
Stanfield, R.L.2
Wilson, I.A.3
-
13
-
-
0028847578
-
Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection
-
Cao Y, Qin L, Zhang L, Safrit J, Ho DD. Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection. N Engl J Med (1995) 332(4):201-8. doi:10.1056/NEJM199501263320401.
-
(1995)
N Engl J Med
, vol.332
, Issue.4
, pp. 201-208
-
-
Cao, Y.1
Qin, L.2
Zhang, L.3
Safrit, J.4
Ho, D.D.5
-
14
-
-
18144429071
-
Characterization of human immunodeficiency virus type 1 (HIV-1) envelope variation and neutralizing antibody responses during transmission of HIV-1 subtype B
-
Frost SD, Liu Y, Pond SL, Chappey C, Wrin T, Petropoulos CJ, et al. Characterization of human immunodeficiency virus type 1 (HIV-1) envelope variation and neutralizing antibody responses during transmission of HIV-1 subtype B. J Virol (2005) 79(10):6523-7. doi:10.1128/JVI.79.10.6523-6527.2005.
-
(2005)
J Virol
, vol.79
, Issue.10
, pp. 6523-6527
-
-
Frost, S.D.1
Liu, Y.2
Pond, S.L.3
Chappey, C.4
Wrin, T.5
Petropoulos, C.J.6
-
15
-
-
0026044947
-
Neutralization of divergent HIV-1 isolates by conformation-dependent human antibodies to Gp120
-
Steimer KS, Scandella CJ, Skiles PV, Haigwood NL. Neutralization of divergent HIV-1 isolates by conformation-dependent human antibodies to Gp120. Science (1991) 254(5028):105-8. doi:10.1126/science.1718036.
-
(1991)
Science
, vol.254
, Issue.5028
, pp. 105-108
-
-
Steimer, K.S.1
Scandella, C.J.2
Skiles, P.V.3
Haigwood, N.L.4
-
16
-
-
0031719015
-
Common themes of antibody maturation to simian immunodeficiency virus, simian-human immunodeficiency virus, and human immunodeficiency virus type 1 infections
-
Cole KS, Murphey-Corb M, Narayan O, Joag SV, Shaw GM, Montelaro RC. Common themes of antibody maturation to simian immunodeficiency virus, simian-human immunodeficiency virus, and human immunodeficiency virus type 1 infections. J Virol (1998) 72(10):7852-9.
-
(1998)
J Virol
, vol.72
, Issue.10
, pp. 7852-7859
-
-
Cole, K.S.1
Murphey-Corb, M.2
Narayan, O.3
Joag, S.V.4
Shaw, G.M.5
Montelaro, R.C.6
-
17
-
-
0028155283
-
Generation of human monoclonal antibodies against HIV-1 proteins; electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization
-
Buchacher A, Predl R, Strutzenberger K, Steinfellner W, Trkola A, Purtscher M, et al. Generation of human monoclonal antibodies against HIV-1 proteins; electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization. AIDS Res Hum Retroviruses (1994) 10(4):359-69. doi:10.1089/aid.1994.10.359.
-
(1994)
AIDS Res Hum Retroviruses
, vol.10
, Issue.4
, pp. 359-369
-
-
Buchacher, A.1
Predl, R.2
Strutzenberger, K.3
Steinfellner, W.4
Trkola, A.5
Purtscher, M.6
-
18
-
-
0027985431
-
Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
-
Burton DR, Pyati J, Koduri R, Sharp SJ, Thornton GB, Parren PW, et al. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. Science (1994) 266(5187):1024-7. doi:10.1126/science.7973652.
-
(1994)
Science
, vol.266
, Issue.5187
, pp. 1024-1027
-
-
Burton, D.R.1
Pyati, J.2
Koduri, R.3
Sharp, S.J.4
Thornton, G.B.5
Parren, P.W.6
-
19
-
-
0027311936
-
Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120
-
Gorny MK, Xu JY, Karwowska S, Buchbinder A, Zolla-Pazner S. Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120. J Immunol (1993) 150(2):635-43.
-
(1993)
J Immunol
, vol.150
, Issue.2
, pp. 635-643
-
-
Gorny, M.K.1
Xu, J.Y.2
Karwowska, S.3
Buchbinder, A.4
Zolla-Pazner, S.5
-
20
-
-
0027378573
-
A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
-
Muster T, Steindl F, Purtscher M, Trkola A, Klima A, Himmler G, et al. A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1. J Virol (1993) 67(11):6642-7.
-
(1993)
J Virol
, vol.67
, Issue.11
, pp. 6642-6647
-
-
Muster, T.1
Steindl, F.2
Purtscher, M.3
Trkola, A.4
Klima, A.5
Himmler, G.6
-
21
-
-
9044241681
-
Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
-
Trkola A, Purtscher M, Muster T, Ballaun C, Buchacher A, Sullivan N, et al. Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1. J Virol (1996) 70(2):1100-8.
-
(1996)
J Virol
, vol.70
, Issue.2
, pp. 1100-1108
-
-
Trkola, A.1
Purtscher, M.2
Muster, T.3
Ballaun, C.4
Buchacher, A.5
Sullivan, N.6
-
22
-
-
13844255333
-
Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41
-
Cardoso RM, Zwick MB, Stanfield RL, Kunert R, Binley JM, Katinger H, et al. Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41. Immunity (2005) 22(2):163-73. doi:10.1016/j.immuni.2004.12.011.
-
(2005)
Immunity
, vol.22
, Issue.2
, pp. 163-173
-
-
Cardoso, R.M.1
Zwick, M.B.2
Stanfield, R.L.3
Kunert, R.4
Binley, J.M.5
Katinger, H.6
-
23
-
-
4544379899
-
Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope
-
Ofek G, Tang M, Sambor A, Katinger H, Mascola JR, Wyatt R, et al. Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope. J Virol (2004) 78(19):10724-37. doi:10.1128/JVI.78.19.10724-10737.2004.
-
(2004)
J Virol
, vol.78
, Issue.19
, pp. 10724-10737
-
-
Ofek, G.1
Tang, M.2
Sambor, A.3
Katinger, H.4
Mascola, J.R.5
Wyatt, R.6
-
24
-
-
33646146379
-
GP120: target for neutralizing HIV-1 antibodies
-
Pantophlet R, Burton DR. GP120: target for neutralizing HIV-1 antibodies. Annu Rev Immunol (2006) 24:739-69. doi:10.1146/annurev.immunol.24.021605.090557.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 739-769
-
-
Pantophlet, R.1
Burton, D.R.2
-
25
-
-
33847101745
-
Structural definition of a conserved neutralization epitope on HIV-1 gp120
-
Zhou T, Xu L, Dey B, Hessell AJ, Van Ryk D, Xiang SH, et al. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature (2007) 445(7129):732-7. doi:10.1038/nature05580.
-
(2007)
Nature
, vol.445
, Issue.7129
, pp. 732-737
-
-
Zhou, T.1
Xu, L.2
Dey, B.3
Hessell, A.J.4
Van Ryk, D.5
Xiang, S.H.6
-
26
-
-
0034759882
-
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41
-
Zwick MB, Labrijn AF, Wang M, Spenlehauer C, Saphire EO, Binley JM, et al. Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. J Virol (2001) 75(22):10892-905. doi:10.1128/JVI.75.22.10892-10905.2001.
-
(2001)
J Virol
, vol.75
, Issue.22
, pp. 10892-10905
-
-
Zwick, M.B.1
Labrijn, A.F.2
Wang, M.3
Spenlehauer, C.4
Saphire, E.O.5
Binley, J.M.6
-
27
-
-
0033952103
-
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
-
Baba TW, Liska V, Hofmann-Lehmann R, Vlasak J, Xu W, Ayehunie S, et al. Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. Nat Med (2000) 6(2):200-6. doi:10.1038/72309.
-
(2000)
Nat Med
, vol.6
, Issue.2
, pp. 200-206
-
-
Baba, T.W.1
Liska, V.2
Hofmann-Lehmann, R.3
Vlasak, J.4
Xu, W.5
Ayehunie, S.6
-
28
-
-
34548496893
-
Fc receptor but not complement binding is important in antibody protection against HIV
-
Hessell AJ, Hangartner L, Hunter M, Havenith CE, Beurskens FJ, Bakker JM, et al. Fc receptor but not complement binding is important in antibody protection against HIV. Nature (2007) 449(7158):101-4. doi:10.1038/nature06106.
-
(2007)
Nature
, vol.449
, Issue.7158
, pp. 101-104
-
-
Hessell, A.J.1
Hangartner, L.2
Hunter, M.3
Havenith, C.E.4
Beurskens, F.J.5
Bakker, J.M.6
-
29
-
-
68349160853
-
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
-
Hessell AJ, Poignard P, Hunter M, Hangartner L, Tehrani DM, Bleeker WK, et al. Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques. Nat Med (2009) 15(8):951-4. doi:10.1038/nm.1974.
-
(2009)
Nat Med
, vol.15
, Issue.8
, pp. 951-954
-
-
Hessell, A.J.1
Poignard, P.2
Hunter, M.3
Hangartner, L.4
Tehrani, D.M.5
Bleeker, W.K.6
-
30
-
-
67249131966
-
Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers
-
Hessell AJ, Rakasz EG, Poignard P, Hangartner L, Landucci G, Forthal DN, et al. Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers. PLoS Pathog (2009) 5(5):e1000433. doi:10.1371/journal.ppat.1000433.
-
(2009)
PLoS Pathog
, vol.5
, Issue.5
-
-
Hessell, A.J.1
Rakasz, E.G.2
Poignard, P.3
Hangartner, L.4
Landucci, G.5
Forthal, D.N.6
-
31
-
-
73949154006
-
Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L
-
Hessell AJ, Rakasz EG, Tehrani DM, Huber M, Weisgrau KL, Landucci G, et al. Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L. J Virol (2010) 84(3):1302-13. doi:10.1128/JVI.01272-09.
-
(2010)
J Virol
, vol.84
, Issue.3
, pp. 1302-1313
-
-
Hessell, A.J.1
Rakasz, E.G.2
Tehrani, D.M.3
Huber, M.4
Weisgrau, K.L.5
Landucci, G.6
-
32
-
-
0032947286
-
Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies
-
Mascola JR, Lewis MG, Stiegler G, Harris D, VanCott TC, Hayes D, et al. Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies. J Virol (1999) 73(5):4009-18.
-
(1999)
J Virol
, vol.73
, Issue.5
, pp. 4009-4018
-
-
Mascola, J.R.1
Lewis, M.G.2
Stiegler, G.3
Harris, D.4
VanCott, T.C.5
Hayes, D.6
-
33
-
-
0033951746
-
Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
-
Mascola JR, Stiegler G, VanCott TC, Katinger H, Carpenter CB, Hanson CE, et al. Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nat Med (2000) 6(2):207-10. doi:10.1038/72318.
-
(2000)
Nat Med
, vol.6
, Issue.2
, pp. 207-210
-
-
Mascola, J.R.1
Stiegler, G.2
VanCott, T.C.3
Katinger, H.4
Carpenter, C.B.5
Hanson, C.E.6
-
34
-
-
0034864776
-
Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro
-
Parren PW, Marx PA, Hessell AJ, Luckay A, Harouse J, Cheng-Mayer C, et al. Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro. J Virol (2001) 75(17):8340-7. doi:10.1128/JVI.75.17.8340-8347.2001.
-
(2001)
J Virol
, vol.75
, Issue.17
, pp. 8340-8347
-
-
Parren, P.W.1
Marx, P.A.2
Hessell, A.J.3
Luckay, A.4
Harouse, J.5
Cheng-Mayer, C.6
-
35
-
-
21344434534
-
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies
-
Haynes BF, Fleming J, St Clair EW, Katinger H, Stiegler G, Kunert R, et al. Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies. Science (2005) 308(5730):1906-8. doi:10.1126/science.1111781.
-
(2005)
Science
, vol.308
, Issue.5730
, pp. 1906-1908
-
-
Haynes, B.F.1
Fleming, J.2
St Clair, E.W.3
Katinger, H.4
Stiegler, G.5
Kunert, R.6
-
36
-
-
73949127978
-
Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies
-
Seaman MS, Janes H, Hawkins N, Grandpre LE, Devoy C, Giri A, et al. Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies. J Virol (2010) 84(3):1439-52. doi:10.1128/JVI.02108-09.
-
(2010)
J Virol
, vol.84
, Issue.3
, pp. 1439-1452
-
-
Seaman, M.S.1
Janes, H.2
Hawkins, N.3
Grandpre, L.E.4
Devoy, C.5
Giri, A.6
-
37
-
-
67650453747
-
Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm
-
Simek MD, Rida W, Priddy FH, Pung P, Carrow E, Laufer DS, et al. Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm. J Virol (2009) 83(14):7337-48. doi:10.1128/JVI.00110-09.
-
(2009)
J Virol
, vol.83
, Issue.14
, pp. 7337-7348
-
-
Simek, M.D.1
Rida, W.2
Priddy, F.H.3
Pung, P.4
Carrow, E.5
Laufer, D.S.6
-
38
-
-
58149399396
-
Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies
-
Doria-Rose NA, Klein RM, Manion MM, O'Dell S, Phogat A, Chakrabarti B, et al. Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies. J Virol (2009) 83(1):188-99. doi:10.1128/JVI.01583-08.
-
(2009)
J Virol
, vol.83
, Issue.1
, pp. 188-199
-
-
Doria-Rose, N.A.1
Klein, R.M.2
Manion, M.M.3
O'Dell, S.4
Phogat, A.5
Chakrabarti, B.6
-
39
-
-
84892365659
-
Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection
-
Hraber P, Seaman MS, Bailer RT, Mascola JR, Montefiori DC, Korber BT. Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection. AIDS (2014) 28(2):163-9. doi:10.1097/QAD.0000000000000106.
-
(2014)
AIDS
, vol.28
, Issue.2
, pp. 163-169
-
-
Hraber, P.1
Seaman, M.S.2
Bailer, R.T.3
Mascola, J.R.4
Montefiori, D.C.5
Korber, B.T.6
-
40
-
-
8644251891
-
Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies
-
Binley JM, Wrin T, Korber B, Zwick MB, Wang M, Chappey C, et al. Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies. J Virol (2004) 78(23):13232-52. doi:10.1128/JVI.78.23.13232-13252.2004.
-
(2004)
J Virol
, vol.78
, Issue.23
, pp. 13232-13252
-
-
Binley, J.M.1
Wrin, T.2
Korber, B.3
Zwick, M.B.4
Wang, M.5
Chappey, C.6
-
41
-
-
34948854718
-
Broad HIV-1 neutralization mediated by CD4-binding site antibodies
-
Li Y, Migueles SA, Welcher B, Svehla K, Phogat A, Louder MK, et al. Broad HIV-1 neutralization mediated by CD4-binding site antibodies. Nat Med (2007) 13(9):1032-4. doi:10.1038/nm1624.
-
(2007)
Nat Med
, vol.13
, Issue.9
, pp. 1032-1034
-
-
Li, Y.1
Migueles, S.A.2
Welcher, B.3
Svehla, K.4
Phogat, A.5
Louder, M.K.6
-
42
-
-
23244467373
-
Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccines
-
Mascola JR, D'Souza P, Gilbert P, Hahn BH, Haigwood NL, Morris L, et al. Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccines. J Virol (2005) 79(16):10103-7. doi:10.1128/JVI.79.16.10103-10107.2005.
-
(2005)
J Virol
, vol.79
, Issue.16
, pp. 10103-10107
-
-
Mascola, J.R.1
D'Souza, P.2
Gilbert, P.3
Hahn, B.H.4
Haigwood, N.L.5
Morris, L.6
-
43
-
-
63849131879
-
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
-
Scheid JF, Mouquet H, Feldhahn N, Seaman MS, Velinzon K, Pietzsch J, et al. Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals. Nature (2009) 458(7238):636-40. doi:10.1038/nature07930.
-
(2009)
Nature
, vol.458
, Issue.7238
, pp. 636-640
-
-
Scheid, J.F.1
Mouquet, H.2
Feldhahn, N.3
Seaman, M.S.4
Velinzon, K.5
Pietzsch, J.6
-
44
-
-
80052925616
-
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding
-
Scheid JF, Mouquet H, Ueberheide B, Diskin R, Klein F, Oliveira TY, et al. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science (2011) 333(6049):1633-7. doi:10.1126/science.1207227.
-
(2011)
Science
, vol.333
, Issue.6049
, pp. 1633-1637
-
-
Scheid, J.F.1
Mouquet, H.2
Ueberheide, B.3
Diskin, R.4
Klein, F.5
Oliveira, T.Y.6
-
45
-
-
80053132436
-
Broad neutralization coverage of HIV by multiple highly potent antibodies
-
Walker LM, Huber M, Doores KJ, Falkowska E, Pejchal R, Julien JP, et al. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature (2011) 477(7365):466-70. doi:10.1038/nature10373.
-
(2011)
Nature
, vol.477
, Issue.7365
, pp. 466-470
-
-
Walker, L.M.1
Huber, M.2
Doores, K.J.3
Falkowska, E.4
Pejchal, R.5
Julien, J.P.6
-
46
-
-
70349887757
-
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
-
Walker LM, Phogat SK, Chan-Hui PY, Wagner D, Phung P, Goss JL, et al. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science (2009) 326(5950):285-9. doi:10.1126/science.1178746.
-
(2009)
Science
, vol.326
, Issue.5950
, pp. 285-289
-
-
Walker, L.M.1
Phogat, S.K.2
Chan-Hui, P.Y.3
Wagner, D.4
Phung, P.5
Goss, J.L.6
-
47
-
-
77954920017
-
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
-
Wu X, Yang ZY, Li Y, Hogerkorp CM, Schief WR, Seaman MS, et al. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science (2010) 329(5993):856-61. doi:10.1126/science.1187659.
-
(2010)
Science
, vol.329
, Issue.5993
, pp. 856-861
-
-
Wu, X.1
Yang, Z.Y.2
Li, Y.3
Hogerkorp, C.M.4
Schief, W.R.5
Seaman, M.S.6
-
48
-
-
80052942203
-
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing
-
Wu X, Zhou T, Zhu J, Zhang B, Georgiev I, Wang C, et al. Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science (2011) 333(6049):1593-602. doi:10.1126/science.1207532.
-
(2011)
Science
, vol.333
, Issue.6049
, pp. 1593-1602
-
-
Wu, X.1
Zhou, T.2
Zhu, J.3
Zhang, B.4
Georgiev, I.5
Wang, C.6
-
49
-
-
84866443327
-
Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein
-
Klein F, Gaebler C, Mouquet H, Sather DN, Lehmann C, Scheid JF, et al. Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein. J Exp Med (2012) 209(8):1469-79. doi:10.1084/jem.20120423.
-
(2012)
J Exp Med
, vol.209
, Issue.8
, pp. 1469-1479
-
-
Klein, F.1
Gaebler, C.2
Mouquet, H.3
Sather, D.N.4
Lehmann, C.5
Scheid, J.F.6
-
50
-
-
63749100579
-
A method for identification of HIV gp140 binding memory B cells in human blood
-
Scheid JF, Mouquet H, Feldhahn N, Walker BD, Pereyra F, Cutrell E, et al. A method for identification of HIV gp140 binding memory B cells in human blood. J Immunol Methods (2009) 343(2):65-7. doi:10.1016/j.jim.2008.11.012.
-
(2009)
J Immunol Methods
, vol.343
, Issue.2
, pp. 65-67
-
-
Scheid, J.F.1
Mouquet, H.2
Feldhahn, N.3
Walker, B.D.4
Pereyra, F.5
Cutrell, E.6
-
51
-
-
36849031722
-
Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
-
Tiller T, Meffre E, Yurasov S, Tsuiji M, Nussenzweig MC, Wardemann H. Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning. J Immunol Methods (2008) 329(1-2):112-24. doi:10.1016/j.jim.2007.09.017.
-
(2008)
J Immunol Methods
, vol.329
, Issue.1-2
, pp. 112-124
-
-
Tiller, T.1
Meffre, E.2
Yurasov, S.3
Tsuiji, M.4
Nussenzweig, M.C.5
Wardemann, H.6
-
52
-
-
0041689676
-
Predominant autoantibody production by early human B cell precursors
-
Wardemann H, Yurasov S, Schaefer A, Young JW, Meffre E, Nussenzweig MC. Predominant autoantibody production by early human B cell precursors. Science (2003) 301(5638):1374-7. doi:10.1126/science.1086907.
-
(2003)
Science
, vol.301
, Issue.5638
, pp. 1374-1377
-
-
Wardemann, H.1
Yurasov, S.2
Schaefer, A.3
Young, J.W.4
Meffre, E.5
Nussenzweig, M.C.6
-
53
-
-
44449118948
-
Rapid cloning of high-affinity human monoclonal antibodies against influenza virus
-
Wrammert J, Smith K, Miller J, Langley WA, Kokko K, Larsen C, et al. Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature (2008) 453(7195):667-71. doi:10.1038/nature06890.
-
(2008)
Nature
, vol.453
, Issue.7195
, pp. 667-671
-
-
Wrammert, J.1
Smith, K.2
Miller, J.3
Langley, W.A.4
Kokko, K.5
Larsen, C.6
-
54
-
-
77649318846
-
Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals
-
Corti D, Langedijk JP, Hinz A, Seaman MS, Vanzetta F, Fernandez-Rodriguez BM, et al. Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals. PLoS One (2010) 5(1):e8805. doi:10.1371/journal.pone.0008805.
-
(2010)
PLoS One
, vol.5
, Issue.1
-
-
Corti, D.1
Langedijk, J.P.2
Hinz, A.3
Seaman, M.S.4
Vanzetta, F.5
Fernandez-Rodriguez, B.M.6
-
55
-
-
84866493348
-
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
-
Huang J, Ofek G, Laub L, Louder MK, Doria-Rose NA, Longo NS, et al. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature (2012) 491(7424):406-12. doi:10.1038/nature11544.
-
(2012)
Nature
, vol.491
, Issue.7424
, pp. 406-412
-
-
Huang, J.1
Ofek, G.2
Laub, L.3
Louder, M.K.4
Doria-Rose, N.A.5
Longo, N.S.6
-
56
-
-
84869831194
-
Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
-
Mouquet H, Scharf L, Euler Z, Liu Y, Eden C, Scheid JF, et al. Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies. Proc Natl Acad Sci U S A (2012) 109(47):E3268-77. doi:10.1073/pnas.1217207109.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.47
, pp. E3268-E3277
-
-
Mouquet, H.1
Scharf, L.2
Euler, Z.3
Liu, Y.4
Eden, C.5
Scheid, J.F.6
-
57
-
-
84969219469
-
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
-
Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, et al. Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody. Science (2016) 352(6287):828-33. doi:10.1126/science.aae0474.
-
(2016)
Science
, vol.352
, Issue.6287
, pp. 828-833
-
-
Kong, R.1
Xu, K.2
Zhou, T.3
Acharya, P.4
Lemmin, T.5
Liu, K.6
-
58
-
-
84866843530
-
A mouse model for HIV-1 entry
-
Pietzsch J, Gruell H, Bournazos S, Donovan BM, Klein F, Diskin R, et al. A mouse model for HIV-1 entry. Proc Natl Acad Sci U S A (2012) 109(39):15859-64. doi:10.1073/pnas.1213409109.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.39
, pp. 15859-15864
-
-
Pietzsch, J.1
Gruell, H.2
Bournazos, S.3
Donovan, B.M.4
Klein, F.5
Diskin, R.6
-
59
-
-
84869232528
-
Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo
-
Moldt B, Rakasz EG, Schultz N, Chan-Hui PY, Swiderek K, Weisgrau KL, et al. Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo. Proc Natl Acad Sci U S A (2012) 109(46):18921-5. doi:10.1073/pnas.1214785109.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.46
, pp. 18921-18925
-
-
Moldt, B.1
Rakasz, E.G.2
Schultz, N.3
Chan-Hui, P.Y.4
Swiderek, K.5
Weisgrau, K.L.6
-
60
-
-
84904497424
-
Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor
-
Pegu A, Yang ZY, Boyington JC, Wu L, Ko SY, Schmidt SD, et al. Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor. Sci Transl Med (2014) 6(243):243ra88. doi:10.1126/scitranslmed.3008992.
-
(2014)
Sci Transl Med
, vol.6
, Issue.243
-
-
Pegu, A.1
Yang, Z.Y.2
Boyington, J.C.3
Wu, L.4
Ko, S.Y.5
Schmidt, S.D.6
-
61
-
-
84907971356
-
Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo
-
Rudicell RS, Kwon YD, Ko SY, Pegu A, Louder MK, Georgiev IS, et al. Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo. J Virol (2014) 88(21):12669-82. doi:10.1128/JVI.02213-14.
-
(2014)
J Virol
, vol.88
, Issue.21
, pp. 12669-12682
-
-
Rudicell, R.S.1
Kwon, Y.D.2
Ko, S.Y.3
Pegu, A.4
Louder, M.K.5
Georgiev, I.S.6
-
62
-
-
84907212727
-
Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques
-
Shingai M, Donau OK, Plishka RJ, Buckler-White A, Mascola JR, Nabel GJ, et al. Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques. J Exp Med (2014) 211(10):2061-74. doi:10.1084/jem.20132494.
-
(2014)
J Exp Med
, vol.211
, Issue.10
, pp. 2061-2074
-
-
Shingai, M.1
Donau, O.K.2
Plishka, R.J.3
Buckler-White, A.4
Mascola, J.R.5
Nabel, G.J.6
-
63
-
-
84907983318
-
Enhanced neonatal Fc receptor function improves protection against primate SHIV infection
-
Ko SY, Pegu A, Rudicell RS, Yang ZY, Joyce MG, Chen X, et al. Enhanced neonatal Fc receptor function improves protection against primate SHIV infection. Nature (2014) 514(7524):642-5. doi:10.1038/nature13612.
-
(2014)
Nature
, vol.514
, Issue.7524
, pp. 642-645
-
-
Ko, S.Y.1
Pegu, A.2
Rudicell, R.S.3
Yang, Z.Y.4
Joyce, M.G.5
Chen, X.6
-
64
-
-
84966389751
-
A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges
-
Gautam R, Nishimura Y, Pegu A, Nason MC, Klein F, Gazumyan A, et al. A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges. Nature (2016) 533(7601):105-9. doi:10.1038/nature17677.
-
(2016)
Nature
, vol.533
, Issue.7601
, pp. 105-109
-
-
Gautam, R.1
Nishimura, Y.2
Pegu, A.3
Nason, M.C.4
Klein, F.5
Gazumyan, A.6
-
65
-
-
8844219655
-
Passive immunization with the anti-HIV-1 human monoclonal antibody (hMAb) 4E10 and the hMAb combination 4E10/2F5/2G12
-
Armbruster C, Stiegler GM, Vcelar BA, Jäger W, Köller U, Jilch R, et al. Passive immunization with the anti-HIV-1 human monoclonal antibody (hMAb) 4E10 and the hMAb combination 4E10/2F5/2G12. J Antimicrob Chemother (2004) 54(5):915-20. doi:10.1093/jac/dkh428.
-
(2004)
J Antimicrob Chemother
, vol.54
, Issue.5
, pp. 915-920
-
-
Armbruster, C.1
Stiegler, G.M.2
Vcelar, B.A.3
Jäger, W.4
Köller, U.5
Jilch, R.6
-
66
-
-
35148864699
-
Adjunctive passive immunotherapy in human immunodeficiency virus type 1-infected individuals treated with antiviral therapy during acute and early infection
-
Mehandru S, Vcelar B, Wrin T, Stiegler G, Joos B, Mohri H, et al. Adjunctive passive immunotherapy in human immunodeficiency virus type 1-infected individuals treated with antiviral therapy during acute and early infection. J Virol (2007) 81(20):11016-31. doi:10.1128/JVI.01340-07.
-
(2007)
J Virol
, vol.81
, Issue.20
, pp. 11016-11031
-
-
Mehandru, S.1
Vcelar, B.2
Wrin, T.3
Stiegler, G.4
Joos, B.5
Mohri, H.6
-
67
-
-
0033119374
-
Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo
-
Poignard P, Sabbe R, Picchio GR, Wang M, Gulizia RJ, Katinger H, et al. Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo. Immunity (1999) 10(4):431-8. doi:10.1016/S1074-7613(00)80043-6.
-
(1999)
Immunity
, vol.10
, Issue.4
, pp. 431-438
-
-
Poignard, P.1
Sabbe, R.2
Picchio, G.R.3
Wang, M.4
Gulizia, R.J.5
Katinger, H.6
-
68
-
-
20944446452
-
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
-
Trkola A, Kuster H, Rusert P, Joos B, Fischer M, Leemann C, et al. Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies. Nat Med (2005) 11(6):615-22. doi:10.1038/nm1244.
-
(2005)
Nat Med
, vol.11
, Issue.6
, pp. 615-622
-
-
Trkola, A.1
Kuster, H.2
Rusert, P.3
Joos, B.4
Fischer, M.5
Leemann, C.6
-
69
-
-
84870562234
-
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
-
Klein F, Halper-Stromberg A, Horwitz JA, Gruell H, Scheid JF, Bournazos S, et al. HIV therapy by a combination of broadly neutralizing antibodies in humanized mice. Nature (2012) 492(7427):118-22. doi:10.1038/nature11604.
-
(2012)
Nature
, vol.492
, Issue.7427
, pp. 118-122
-
-
Klein, F.1
Halper-Stromberg, A.2
Horwitz, J.A.3
Gruell, H.4
Scheid, J.F.5
Bournazos, S.6
-
70
-
-
84885338257
-
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice
-
Horwitz JA, Halper-Stromberg A, Mouquet H, Gitlin AD, Tretiakova A, Eisenreich TR, et al. HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proc Natl Acad Sci U S A (2013) 110(41):16538-43. doi:10.1073/pnas.1315295110.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.41
, pp. 16538-16543
-
-
Horwitz, J.A.1
Halper-Stromberg, A.2
Mouquet, H.3
Gitlin, A.D.4
Tretiakova, A.5
Eisenreich, T.R.6
-
71
-
-
84928574709
-
Animal models in HIV-1 protection and therapy
-
Hessell AJ, Haigwood NL. Animal models in HIV-1 protection and therapy. Curr Opin HIV AIDS (2015) 10(3):170-6. doi:10.1097/COH.0000000000000152.
-
(2015)
Curr Opin HIV AIDS
, vol.10
, Issue.3
, pp. 170-176
-
-
Hessell, A.J.1
Haigwood, N.L.2
-
72
-
-
84885967137
-
Neutralizing polyclonal IgG present during acute infection prevents rapid disease onset in simian-human immunodeficiency virus SHIVSF162P3-infected infant rhesus macaques
-
Jaworski JP, Kobie J, Brower Z, Malherbe DC, Landucci G, Sutton WF, et al. Neutralizing polyclonal IgG present during acute infection prevents rapid disease onset in simian-human immunodeficiency virus SHIVSF162P3-infected infant rhesus macaques. J Virol (2013) 87(19):10447-59. doi:10.1128/JVI.00049-13.
-
(2013)
J Virol
, vol.87
, Issue.19
, pp. 10447-10459
-
-
Jaworski, J.P.1
Kobie, J.2
Brower, Z.3
Malherbe, D.C.4
Landucci, G.5
Sutton, W.F.6
-
73
-
-
84887626950
-
Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys
-
Barouch DH, Whitney JB, Moldt B, Klein F, Oliveira TY, Liu J, et al. Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys. Nature (2013) 503(7475):224-8. doi:10.1038/nature12744.
-
(2013)
Nature
, vol.503
, Issue.7475
, pp. 224-228
-
-
Barouch, D.H.1
Whitney, J.B.2
Moldt, B.3
Klein, F.4
Oliveira, T.Y.5
Liu, J.6
-
74
-
-
84887627657
-
Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia
-
Shingai M, Nishimura Y, Klein F, Mouquet H, Donau OK, Plishka R, et al. Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia. Nature (2013) 503(7475):277-80. doi:10.1038/nature12746.
-
(2013)
Nature
, vol.503
, Issue.7475
, pp. 277-280
-
-
Shingai, M.1
Nishimura, Y.2
Klein, F.3
Mouquet, H.4
Donau, O.K.5
Plishka, R.6
-
75
-
-
84928405730
-
Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117
-
Caskey M, Klein F, Lorenzi JC, Seaman MS, West AP Jr, Buckley N, et al. Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117. Nature (2015) 522(7557):487-91. doi:10.1038/nature14411.
-
(2015)
Nature
, vol.522
, Issue.7557
, pp. 487-491
-
-
Caskey, M.1
Klein, F.2
Lorenzi, J.C.3
Seaman, M.S.4
West, A.P.5
Buckley, N.6
-
76
-
-
84954445565
-
Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection
-
Lynch RM, Boritz E, Coates EE, DeZure A, Madden P, Costner P, et al. Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection. Sci Transl Med (2015) 7(319):319ra206. doi:10.1126/scitranslmed.aad5752.
-
(2015)
Sci Transl Med
, vol.7
, Issue.319
-
-
Lynch, R.M.1
Boritz, E.2
Coates, E.E.3
DeZure, A.4
Madden, P.5
Costner, P.6
-
77
-
-
84976406858
-
HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption
-
Scheid JF, Horwitz JA, Bar-On Y, Kreider EF, Lu CL, Lorenzi JC, et al. HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption. Nature (2016) 535(7613):556-60. doi:10.1038/nature18929.
-
(2016)
Nature
, vol.535
, Issue.7613
, pp. 556-560
-
-
Scheid, J.F.1
Horwitz, J.A.2
Bar-On, Y.3
Kreider, E.F.4
Lu, C.L.5
Lorenzi, J.C.6
-
78
-
-
84997817411
-
Effect of HIV antibody VRC01 on viral rebound after treatment interruption
-
Bar KJ, Sneller MC, Harrison LJ, Justement JS, Overton ET, Petrone ME, et al. Effect of HIV antibody VRC01 on viral rebound after treatment interruption. N Engl J Med (2016) 375(375):2037-50. doi:10.1056/NEJMoa1608243.
-
(2016)
N Engl J Med
, vol.375
, Issue.375
, pp. 2037-2050
-
-
Bar, K.J.1
Sneller, M.C.2
Harrison, L.J.3
Justement, J.S.4
Overton, E.T.5
Petrone, M.E.6
-
79
-
-
53449093632
-
Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections
-
Brenchley JM, Paiardini M, Knox KS, Asher AI, Cervasi B, Asher TE, et al. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood (2008) 112(7):2826-35. doi:10.1182/blood-2008-05-159301.
-
(2008)
Blood
, vol.112
, Issue.7
, pp. 2826-2835
-
-
Brenchley, J.M.1
Paiardini, M.2
Knox, K.S.3
Asher, A.I.4
Cervasi, B.5
Asher, T.E.6
-
80
-
-
33745939869
-
Systemic vaccination prevents the total destruction of mucosal CD4 T cells during acute SIV challenge
-
Mattapallil JJ, Hill B, Douek DC, Roederer M. Systemic vaccination prevents the total destruction of mucosal CD4 T cells during acute SIV challenge. J Med Primatol (2006) 35(4-5):217-24. doi:10.1111/j.1600-0684.2006.00170.x.
-
(2006)
J Med Primatol
, vol.35
, Issue.4-5
, pp. 217-224
-
-
Mattapallil, J.J.1
Hill, B.2
Douek, D.C.3
Roederer, M.4
-
81
-
-
33745363316
-
Immunopathogenesis of acute AIDS virus infection
-
Picker LJ. Immunopathogenesis of acute AIDS virus infection. Curr Opin Immunol (2006) 18(4):399-405. doi:10.1016/j.coi.2006.05.001.
-
(2006)
Curr Opin Immunol
, vol.18
, Issue.4
, pp. 399-405
-
-
Picker, L.J.1
-
82
-
-
0031925896
-
Gastrointestinal T lymphocytes retain high potential for cytokine responses but have severe CD4(+) T-cell depletion at all stages of simian immunodeficiency virus infection compared to peripheral lymphocytes
-
Smit-McBride Z, Mattapallil JJ, McChesney M, Ferrick D, Dandekar S. Gastrointestinal T lymphocytes retain high potential for cytokine responses but have severe CD4(+) T-cell depletion at all stages of simian immunodeficiency virus infection compared to peripheral lymphocytes. J Virol (1998) 72(8):6646-56.
-
(1998)
J Virol
, vol.72
, Issue.8
, pp. 6646-6656
-
-
Smit-McBride, Z.1
Mattapallil, J.J.2
McChesney, M.3
Ferrick, D.4
Dandekar, S.5
-
83
-
-
0032540418
-
Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection
-
Veazey RS, DeMaria M, Chalifoux LV, Shvetz DE, Pauley DR, Knight HL, et al. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science (1998) 280(5362):427-31. doi:10.1126/science.280.5362.427.
-
(1998)
Science
, vol.280
, Issue.5362
, pp. 427-431
-
-
Veazey, R.S.1
DeMaria, M.2
Chalifoux, L.V.3
Shvetz, D.E.4
Pauley, D.R.5
Knight, H.L.6
-
84
-
-
77649197874
-
Evidence of early B-cell dysregulation in simian immunodeficiency virus infection: rapid depletion of naive and memory B-cell subsets with delayed reconstitution of the naive B-cell population
-
Kuhrt D, Faith SA, Leone A, Rohankedkar M, Sodora DL, Picker LJ, et al. Evidence of early B-cell dysregulation in simian immunodeficiency virus infection: rapid depletion of naive and memory B-cell subsets with delayed reconstitution of the naive B-cell population. J Virol (2010) 84(5):2466-76. doi:10.1128/JVI.01966-09.
-
(2010)
J Virol
, vol.84
, Issue.5
, pp. 2466-2476
-
-
Kuhrt, D.1
Faith, S.A.2
Leone, A.3
Rohankedkar, M.4
Sodora, D.L.5
Picker, L.J.6
-
85
-
-
68049135892
-
Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection
-
Levesque MC, Moody MA, Hwang KK, Marshall DJ, Whitesides JF, Amos JD, et al. Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection. PLoS Med (2009) 6(7):e1000107. doi:10.1371/journal.pmed.1000107.
-
(2009)
PLoS Med
, vol.6
, Issue.7
-
-
Levesque, M.C.1
Moody, M.A.2
Hwang, K.K.3
Marshall, D.J.4
Whitesides, J.F.5
Amos, J.D.6
-
86
-
-
67650178327
-
Tissue-specific B-cell dysfunction and generalized memory B-cell loss during acute SIV infection
-
Peruchon S, Chaoul N, Burelout C, Delache B, Brochard P, Laurent P, et al. Tissue-specific B-cell dysfunction and generalized memory B-cell loss during acute SIV infection. PLoS One (2009) 4(6):e5966. doi:10.1371/journal.pone.0005966.
-
(2009)
PLoS One
, vol.4
, Issue.6
-
-
Peruchon, S.1
Chaoul, N.2
Burelout, C.3
Delache, B.4
Brochard, P.5
Laurent, P.6
-
87
-
-
63149142646
-
B cells in HIV infection and disease
-
Moir S, Fauci AS. B cells in HIV infection and disease. Nat Rev Immunol (2009) 9(4):235-45. doi:10.1038/nri2524.
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.4
, pp. 235-245
-
-
Moir, S.1
Fauci, A.S.2
-
88
-
-
84859250847
-
Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection
-
Ananworanich J, Schuetz A, Vandergeeten C, Sereti I, de Souza M, Rerknimitr R, et al. Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection. PLoS One (2012) 7(3):e33948. doi:10.1371/journal.pone.0033948.
-
(2012)
PLoS One
, vol.7
, Issue.3
-
-
Ananworanich, J.1
Schuetz, A.2
Vandergeeten, C.3
Sereti, I.4
de Souza, M.5
Rerknimitr, R.6
-
89
-
-
84862189831
-
Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection
-
Archin NM, Vaidya NK, Kuruc JD, Liberty AL, Wiegand A, Kearney MF, et al. Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection. Proc Natl Acad Sci U S A (2012) 109(24):9523-8. doi:10.1073/pnas.1120248109.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.24
, pp. 9523-9528
-
-
Archin, N.M.1
Vaidya, N.K.2
Kuruc, J.D.3
Liberty, A.L.4
Wiegand, A.5
Kearney, M.F.6
-
90
-
-
84905565097
-
Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys
-
Whitney JB, Hill AL, Sanisetty S, Penaloza-MacMaster P, Liu J, Shetty M, et al. Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys. Nature (2014) 512(7512):74-7. doi:10.1038/nature13594.
-
(2014)
Nature
, vol.512
, Issue.7512
, pp. 74-77
-
-
Whitney, J.B.1
Hill, A.L.2
Sanisetty, S.3
Penaloza-MacMaster, P.4
Liu, J.5
Shetty, M.6
-
91
-
-
66149122304
-
Polyfunctional CD4+ T-cell induction in neutralizing antibody-triggered control of simian immunodeficiency virus infection
-
Yamamoto T, Iwamoto N, Yamamoto H, Tsukamoto T, Kuwano T, Takeda A, et al. Polyfunctional CD4+ T-cell induction in neutralizing antibody-triggered control of simian immunodeficiency virus infection. J Virol (2009) 83(11):5514-24. doi:10.1128/JVI.00145-09.
-
(2009)
J Virol
, vol.83
, Issue.11
, pp. 5514-5524
-
-
Yamamoto, T.1
Iwamoto, N.2
Yamamoto, H.3
Tsukamoto, T.4
Kuwano, T.5
Takeda, A.6
-
92
-
-
77953760056
-
Antibody-mediated modulation of immune responses
-
Nimmerjahn F, Ravetch JV. Antibody-mediated modulation of immune responses. Immunol Rev (2010) 236:265-75. doi:10.1111/j.1600-065X.2010.00910.x.
-
(2010)
Immunol Rev
, vol.236
, pp. 265-275
-
-
Nimmerjahn, F.1
Ravetch, J.V.2
-
93
-
-
84966341056
-
HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1
-
Schoofs T, Klein F, Braunschweig M, Kreider EF, Feldmann A, Nogueira L, et al. HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1. Science (2016) 352(6288):997-1001. doi:10.1126/science.aaf0972.
-
(2016)
Science
, vol.352
, Issue.6288
, pp. 997-1001
-
-
Schoofs, T.1
Klein, F.2
Braunschweig, M.3
Kreider, E.F.4
Feldmann, A.5
Nogueira, L.6
-
94
-
-
77957820631
-
Passive neutralizing antibody controls SHIV viremia and enhances B cell responses in infant macaques
-
Ng CT, Jaworski JP, Jayaraman P, Sutton WF, Delio P, Kuller L, et al. Passive neutralizing antibody controls SHIV viremia and enhances B cell responses in infant macaques. Nat Med (2010) 16(10):1117-9. doi:10.1038/nm.2233.
-
(2010)
Nat Med
, vol.16
, Issue.10
, pp. 1117-1119
-
-
Ng, C.T.1
Jaworski, J.P.2
Jayaraman, P.3
Sutton, W.F.4
Delio, P.5
Kuller, L.6
-
95
-
-
84966397893
-
Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo
-
Lu CL, Murakowski DK, Bournazos S, Schoofs T, Sarkar D, Halper-Stromberg A, et al. Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo. Science (2016) 352(6288):1001-4. doi:10.1126/science.aaf1279.
-
(2016)
Science
, vol.352
, Issue.6288
, pp. 1001-1004
-
-
Lu, C.L.1
Murakowski, D.K.2
Bournazos, S.3
Schoofs, T.4
Sarkar, D.5
Halper-Stromberg, A.6
-
96
-
-
84908077691
-
Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity
-
Bournazos S, Klein F, Pietzsch J, Seaman MS, Nussenzweig MC, Ravetch JV. Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity. Cell (2014) 158(6):1243-53. doi:10.1016/j.cell.2014.08.023.
-
(2014)
Cell
, vol.158
, Issue.6
, pp. 1243-1253
-
-
Bournazos, S.1
Klein, F.2
Pietzsch, J.3
Seaman, M.S.4
Nussenzweig, M.C.5
Ravetch, J.V.6
-
97
-
-
84958093143
-
Human immunodeficiency virus type 1 monoclonal antibodies suppress acute simian-human immunodeficiency virus viremia and limit seeding of cell-associated viral reservoirs
-
Bolton DL, Pegu A, Wang K, McGinnis K, Nason M, Foulds K, et al. Human immunodeficiency virus type 1 monoclonal antibodies suppress acute simian-human immunodeficiency virus viremia and limit seeding of cell-associated viral reservoirs. J Virol (2016) 90(3):1321-32. doi:10.1128/JVI.02454-15.
-
(2016)
J Virol
, vol.90
, Issue.3
, pp. 1321-1332
-
-
Bolton, D.L.1
Pegu, A.2
Wang, K.3
McGinnis, K.4
Nason, M.5
Foulds, K.6
-
98
-
-
84961392349
-
Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques
-
Hessell AJ, Jaworski JP, Epson E, Matsuda K, Pandey S, Kahl C, et al. Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques. Nat Med (2016) 22(4):362-8. doi:10.1038/nm.4063.
-
(2016)
Nat Med
, vol.22
, Issue.4
, pp. 362-368
-
-
Hessell, A.J.1
Jaworski, J.P.2
Epson, E.3
Matsuda, K.4
Pandey, S.5
Kahl, C.6
-
99
-
-
84983398137
-
Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus
-
Liu J, Ghneim K, Sok D, Bosche WJ, Li Y, Chipriano E, et al. Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus. Science (2016) 353(6303):1045-9. doi:10.1126/science.aag0491.
-
(2016)
Science
, vol.353
, Issue.6303
, pp. 1045-1049
-
-
Liu, J.1
Ghneim, K.2
Sok, D.3
Bosche, W.J.4
Li, Y.5
Chipriano, E.6
-
100
-
-
84946480939
-
Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV-1 human monoclonal antibody VRC01 in healthy adults
-
Ledgerwood JE, Coates EE, Yamshchikov G, Saunders JG, Holman L, Enama ME, et al. Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV-1 human monoclonal antibody VRC01 in healthy adults. Clin Exp Immunol (2015) 182(3):289-301. doi:10.1111/cei.12692.
-
(2015)
Clin Exp Immunol
, vol.182
, Issue.3
, pp. 289-301
-
-
Ledgerwood, J.E.1
Coates, E.E.2
Yamshchikov, G.3
Saunders, J.G.4
Holman, L.5
Enama, M.E.6
-
101
-
-
84900389177
-
HIV monoclonal antibodies: a new opportunity to further reduce mother-to-child HIV transmission
-
Voronin Y, Mofenson LM, Cunningham CK, Fowler MG, Kaleebu P, McFarland EJ, et al. HIV monoclonal antibodies: a new opportunity to further reduce mother-to-child HIV transmission. PLoS Med (2014) 11(4):e1001616. doi:10.1371/journal.pmed.1001616.
-
(2014)
PLoS Med
, vol.11
, Issue.4
-
-
Voronin, Y.1
Mofenson, L.M.2
Cunningham, C.K.3
Fowler, M.G.4
Kaleebu, P.5
McFarland, E.J.6
-
102
-
-
84999836139
-
Identification of a CD4-binding-site antibody to HIV that evolved near-pan neutralization breadth
-
Huang J, Kang BH, Ishida E, Zhou T, Griesman T, Sheng Z, et al. Identification of a CD4-binding-site antibody to HIV that evolved near-pan neutralization breadth. Immunity (2016) 45(5):1108-21. doi:10.1016/j.immuni.2016.10.027.
-
(2016)
Immunity
, vol.45
, Issue.5
, pp. 1108-1121
-
-
Huang, J.1
Kang, B.H.2
Ishida, E.3
Zhou, T.4
Griesman, T.5
Sheng, Z.6
-
103
-
-
84922982202
-
Improving neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes
-
Kong R, Louder MK, Wagh K, Bailer RT, deCamp A, Greene K, et al. Improving neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes. J Virol (2015) 89(5):2659-71. doi:10.1128/JVI.03136-14.
-
(2015)
J Virol
, vol.89
, Issue.5
, pp. 2659-2671
-
-
Kong, R.1
Louder, M.K.2
Wagh, K.3
Bailer, R.T.4
deCamp, A.5
Greene, K.6
-
104
-
-
84962419508
-
Optimal combinations of broadly neutralizing antibodies for prevention and treatment of HIV-1 clade C infection
-
Wagh K, Bhattacharya T, Williamson C, Robles A, Bayne M, Garrity J, et al. Optimal combinations of broadly neutralizing antibodies for prevention and treatment of HIV-1 clade C infection. PLoS Pathog (2016) 12(3):e1005520. doi:10.1371/journal.ppat.1005520.
-
(2016)
PLoS Pathog
, vol.12
, Issue.3
-
-
Wagh, K.1
Bhattacharya, T.2
Williamson, C.3
Robles, A.4
Bayne, M.5
Garrity, J.6
-
105
-
-
84949921488
-
Bispecific antibodies targeting different epitopes on the HIV-1 envelope exhibit broad and potent neutralization
-
Asokan M, Rudicell RS, Louder M, McKee K, O'Dell S, Stewart-Jones G, et al. Bispecific antibodies targeting different epitopes on the HIV-1 envelope exhibit broad and potent neutralization. J Virol (2015) 89(24):12501-12. doi:10.1128/JVI.02097-15.
-
(2015)
J Virol
, vol.89
, Issue.24
, pp. 12501-12512
-
-
Asokan, M.1
Rudicell, R.S.2
Louder, M.3
McKee, K.4
O'Dell, S.5
Stewart-Jones, G.6
-
106
-
-
84975266475
-
Bispecific antibodies against HIV
-
Montefiori DC. Bispecific antibodies against HIV. Cell (2016) 165(7):1563-4. doi:10.1016/j.cell.2016.06.004.
-
(2016)
Cell
, vol.165
, Issue.7
, pp. 1563-1564
-
-
Montefiori, D.C.1
-
107
-
-
84975270914
-
Bispecific anti-HIV-1 antibodies with enhanced breadth and potency
-
Bournazos S, Gazumyan A, Seaman MS, Nussenzweig MC, Ravetch JV. Bispecific anti-HIV-1 antibodies with enhanced breadth and potency. Cell (2016) 165(7):1609-20. doi:10.1016/j.cell.2016.04.050.
-
(2016)
Cell
, vol.165
, Issue.7
, pp. 1609-1620
-
-
Bournazos, S.1
Gazumyan, A.2
Seaman, M.S.3
Nussenzweig, M.C.4
Ravetch, J.V.5
-
108
-
-
84975221851
-
Engineered bispecific antibodies with exquisite HIV-1-neutralizing activity
-
Huang Y, Yu J, Lanzi A, Yao X, Andrews CD, Tsai L, et al. Engineered bispecific antibodies with exquisite HIV-1-neutralizing activity. Cell (2016) 165(7):1621-31. doi:10.1016/j.cell.2016.05.024.
-
(2016)
Cell
, vol.165
, Issue.7
, pp. 1621-1631
-
-
Huang, Y.1
Yu, J.2
Lanzi, A.3
Yao, X.4
Andrews, C.D.5
Tsai, L.6
-
109
-
-
84945162086
-
Activation and lysis of human CD4 cells latently infected with HIV-1
-
Pegu A, Asokan M, Wu L, Wang K, Hataye J, Casazza JP, et al. Activation and lysis of human CD4 cells latently infected with HIV-1. Nat Commun (2015) 6:8447. doi:10.1038/ncomms9447.
-
(2015)
Nat Commun
, vol.6
, pp. 8447
-
-
Pegu, A.1
Asokan, M.2
Wu, L.3
Wang, K.4
Hataye, J.5
Casazza, J.P.6
-
110
-
-
84855466746
-
Antibody-based protection against HIV infection by vectored immunoprophylaxis
-
Balazs AB, Chen J, Hong CM, Rao DS, Yang L, Baltimore D. Antibody-based protection against HIV infection by vectored immunoprophylaxis. Nature (2012) 481(7379):81-4. doi:10.1038/nature10660.
-
(2012)
Nature
, vol.481
, Issue.7379
, pp. 81-84
-
-
Balazs, A.B.1
Chen, J.2
Hong, C.M.3
Rao, D.S.4
Yang, L.5
Baltimore, D.6
-
111
-
-
84896120124
-
Vectored immunoprophylaxis protects humanized mice from mucosal HIV transmission
-
Balazs AB, Ouyang Y, Hong CM, Chen J, Nguyen SM, Rao DS, et al. Vectored immunoprophylaxis protects humanized mice from mucosal HIV transmission. Nat Med (2014) 20(3):296-300. doi:10.1038/nm.3471.
-
(2014)
Nat Med
, vol.20
, Issue.3
, pp. 296-300
-
-
Balazs, A.B.1
Ouyang, Y.2
Hong, C.M.3
Chen, J.4
Nguyen, S.M.5
Rao, D.S.6
-
112
-
-
84928552521
-
Vectored antibody gene delivery for the prevention or treatment of HIV infection
-
Deal CE, Balazs AB. Vectored antibody gene delivery for the prevention or treatment of HIV infection. Curr Opin HIV AIDS (2015) 10(3):190-7. doi:10.1097/COH.0000000000000145.
-
(2015)
Curr Opin HIV AIDS
, vol.10
, Issue.3
, pp. 190-197
-
-
Deal, C.E.1
Balazs, A.B.2
-
113
-
-
73349094086
-
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
-
Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Kaewkungwal J, Chiu J, Paris R, et al. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med (2009) 361(23):2209-20. doi:10.1056/NEJMoa0908492.
-
(2009)
N Engl J Med
, vol.361
, Issue.23
, pp. 2209-2220
-
-
Rerks-Ngarm, S.1
Pitisuttithum, P.2
Nitayaphan, S.3
Kaewkungwal, J.4
Chiu, J.5
Paris, R.6
-
114
-
-
84859393693
-
Immune-correlates analysis of an HIV-1 vaccine efficacy trial
-
Haynes BF, Gilbert PB, McElrath MJ, Zolla-Pazner S, Tomaras GD, Alam SM, et al. Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med (2012) 366(14):1275-86. doi:10.1056/NEJMoa1113425.
-
(2012)
N Engl J Med
, vol.366
, Issue.14
, pp. 1275-1286
-
-
Haynes, B.F.1
Gilbert, P.B.2
McElrath, M.J.3
Zolla-Pazner, S.4
Tomaras, G.D.5
Alam, S.M.6
-
115
-
-
84863932778
-
Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials
-
Montefiori DC, Karnasuta C, Huang Y, Ahmed H, Gilbert P, de Souza MS, et al. Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials. J Infect Dis (2012) 206(3):431-41. doi:10.1093/infdis/jis367.
-
(2012)
J Infect Dis
, vol.206
, Issue.3
, pp. 431-441
-
-
Montefiori, D.C.1
Karnasuta, C.2
Huang, Y.3
Ahmed, H.4
Gilbert, P.5
de Souza, M.S.6
-
116
-
-
84900467984
-
Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers
-
Blattner C, Lee JH, Sliepen K, Derking R, Falkowska E, de la Peña AT, et al. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers. Immunity (2014) 40(5):669-80. doi:10.1016/j.immuni.2014.04.008.
-
(2014)
Immunity
, vol.40
, Issue.5
, pp. 669-680
-
-
Blattner, C.1
Lee, J.H.2
Sliepen, K.3
Derking, R.4
Falkowska, E.5
de la Peña, A.T.6
-
117
-
-
84899991983
-
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
-
Doria-Rose NA, Schramm CA, Gorman J, Moore PL, Bhiman JN, DeKosky BJ, et al. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature (2014) 509(7498):55-62. doi:10.1038/nature13036.
-
(2014)
Nature
, vol.509
, Issue.7498
, pp. 55-62
-
-
Doria-Rose, N.A.1
Schramm, C.A.2
Gorman, J.3
Moore, P.L.4
Bhiman, J.N.5
DeKosky, B.J.6
-
118
-
-
84900517557
-
Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers
-
Falkowska E, Le KM, Ramos A, Doores KJ, Lee JH, Blattner C, et al. Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers. Immunity (2014) 40(5):657-68. doi:10.1016/j.immuni.2014.04.009.
-
(2014)
Immunity
, vol.40
, Issue.5
, pp. 657-668
-
-
Falkowska, E.1
Le, K.M.2
Ramos, A.3
Doores, K.J.4
Lee, J.H.5
Blattner, C.6
-
119
-
-
84921607768
-
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface
-
Huang J, Kang BH, Pancera M, Lee JH, Tong T, Feng Y, et al. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface. Nature (2014) 515(7525):138-42. doi:10.1038/nature13601.
-
(2014)
Nature
, vol.515
, Issue.7525
, pp. 138-142
-
-
Huang, J.1
Kang, B.H.2
Pancera, M.3
Lee, J.H.4
Tong, T.5
Feng, Y.6
-
120
-
-
84878519611
-
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans
-
Julien JP, Sok D, Khayat R, Lee JH, Doores KJ, Walker LM, et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. PLoS Pathog (2013) 9(5):e1003342. doi:10.1371/journal.ppat.1003342.
-
(2013)
PLoS Pathog
, vol.9
, Issue.5
-
-
Julien, J.P.1
Sok, D.2
Khayat, R.3
Lee, J.H.4
Doores, K.J.5
Walker, L.M.6
-
121
-
-
84880161438
-
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
-
Kong L, Lee JH, Doores KJ, Murin CD, Julien JP, McBride R, et al. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nat Struct Mol Biol (2013) 20(7):796-803. doi:10.1038/nsmb.2594.
-
(2013)
Nat Struct Mol Biol
, vol.20
, Issue.7
, pp. 796-803
-
-
Kong, L.1
Lee, J.H.2
Doores, K.J.3
Murin, C.D.4
Julien, J.P.5
McBride, R.6
-
122
-
-
84876797103
-
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
-
Liao HX, Lynch R, Zhou T, Gao F, Alam SM, Boyd SD, et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature (2013) 496(7446):469-76. doi:10.1038/nature12053.
-
(2013)
Nature
, vol.496
, Issue.7446
, pp. 469-476
-
-
Liao, H.X.1
Lynch, R.2
Zhou, T.3
Gao, F.4
Alam, S.M.5
Boyd, S.D.6
-
123
-
-
83455254775
-
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
-
McLellan JS, Pancera M, Carrico C, Gorman J, Julien JP, Khayat R, et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature (2011) 480(7377):336-43. doi:10.1038/nature10696.
-
(2011)
Nature
, vol.480
, Issue.7377
, pp. 336-343
-
-
McLellan, J.S.1
Pancera, M.2
Carrico, C.3
Gorman, J.4
Julien, J.P.5
Khayat, R.6
-
124
-
-
84880149399
-
Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16
-
Pancera M, Shahzad-Ul-Hussan S, Doria-Rose NA, McLellan JS, Bailer RT, Dai K, et al. Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16. Nat Struct Mol Biol (2013) 20(7):804-13. doi:10.1038/nsmb.2600.
-
(2013)
Nat Struct Mol Biol
, vol.20
, Issue.7
, pp. 804-813
-
-
Pancera, M.1
Shahzad-Ul-Hussan, S.2
Doria-Rose, N.A.3
McLellan, J.S.4
Bailer, R.T.5
Dai, K.6
-
125
-
-
82255179322
-
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield
-
Pejchal R, Doores KJ, Walker LM, Khayat R, Huang PS, Wang SK, et al. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science (2011) 334(6059):1097-103. doi:10.1126/science.1213256.
-
(2011)
Science
, vol.334
, Issue.6059
, pp. 1097-1103
-
-
Pejchal, R.1
Doores, K.J.2
Walker, L.M.3
Khayat, R.4
Huang, P.S.5
Wang, S.K.6
-
126
-
-
77954912140
-
Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1
-
Pejchal R, Walker LM, Stanfield RL, Phogat SK, KoffWC, Poignard P, et al. Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1. Proc Natl Acad Sci U S A (2010) 107(25):11483-8. doi:10.1073/pnas.1004600107.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.25
, pp. 11483-11488
-
-
Pejchal, R.1
Walker, L.M.2
Stanfield, R.L.3
Phogat, S.K.4
Koff, W.C.5
Poignard, P.6
-
127
-
-
84899909771
-
Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike
-
Scharf L, Scheid JF, Lee JH, West AP Jr, Chen C, Gao H, et al. Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike. Cell Rep (2014) 7(3):785-95. doi:10.1016/j.celrep.2014.04.001.
-
(2014)
Cell Rep
, vol.7
, Issue.3
, pp. 785-795
-
-
Scharf, L.1
Scheid, J.F.2
Lee, J.H.3
West, A.P.4
Chen, C.5
Gao, H.6
-
128
-
-
77954943648
-
Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01
-
Zhou T, Georgiev I, Wu X, Yang ZY, Dai K, Finzi A, et al. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science (2010) 329(5993):811-7. doi:10.1126/science.1192819.
-
(2010)
Science
, vol.329
, Issue.5993
, pp. 811-817
-
-
Zhou, T.1
Georgiev, I.2
Wu, X.3
Yang, Z.Y.4
Dai, K.5
Finzi, A.6
-
129
-
-
84882589754
-
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies
-
Zhou T, Zhu J, Wu X, Moquin S, Zhang B, Acharya P, et al. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. Immunity (2013) 39(2):245-58. doi:10.1016/j.immuni.2013.04.012.
-
(2013)
Immunity
, vol.39
, Issue.2
, pp. 245-258
-
-
Zhou, T.1
Zhu, J.2
Wu, X.3
Moquin, S.4
Zhang, B.5
Acharya, P.6
-
130
-
-
84962201516
-
Key gp120 glycans pose roadblocks to the rapid development of VRC01-class antibodies in an HIV-1-infected Chinese donor
-
Kong L, Ju B, Chen Y, He L, Ren L, Liu J, et al. Key gp120 glycans pose roadblocks to the rapid development of VRC01-class antibodies in an HIV-1-infected Chinese donor. Immunity (2016) 44(4):939-50. doi:10.1016/j.immuni.2016.03.006.
-
(2016)
Immunity
, vol.44
, Issue.4
, pp. 939-950
-
-
Kong, L.1
Ju, B.2
Chen, Y.3
He, L.4
Ren, L.5
Liu, J.6
-
131
-
-
84936846696
-
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
-
Kwon YD, Pancera M, Acharya P, Georgiev IS, Crooks ET, Gorman J, et al. Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env. Nat Struct Mol Biol (2015) 22(7):522-31. doi:10.1038/nsmb.3051.
-
(2015)
Nat Struct Mol Biol
, vol.22
, Issue.7
, pp. 522-531
-
-
Kwon, Y.D.1
Pancera, M.2
Acharya, P.3
Georgiev, I.S.4
Crooks, E.T.5
Gorman, J.6
-
132
-
-
84962253716
-
Structural basis for germline antibody recognition of HIV-1 immunogens
-
Scharf L, West AP, Sievers SA, Chen C, Jiang S, Gao H, et al. Structural basis for germline antibody recognition of HIV-1 immunogens. Elife (2016) 5:e13783. doi:10.7554/eLife.13783.
-
(2016)
Elife
, vol.5
-
-
Scharf, L.1
West, A.P.2
Sievers, S.A.3
Chen, C.4
Jiang, S.5
Gao, H.6
-
133
-
-
84907681865
-
Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies
-
Kepler TB, Liao HX, Alam SM, Bhaskarabhatla R, Zhang R, Yandava C, et al. Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies. Cell Host Microbe (2014) 16(3):304-13. doi:10.1016/j.chom.2014.08.006.
-
(2014)
Cell Host Microbe
, vol.16
, Issue.3
, pp. 304-313
-
-
Kepler, T.B.1
Liao, H.X.2
Alam, S.M.3
Bhaskarabhatla, R.4
Zhang, R.5
Yandava, C.6
-
134
-
-
80052531336
-
Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses
-
Mouquet H, Klein F, Scheid JF, Warncke M, Pietzsch J, Oliveira TY, et al. Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. PLoS One (2011) 6(9):e24078. doi:10.1371/journal.pone.0024078.
-
(2011)
PLoS One
, vol.6
, Issue.9
-
-
Mouquet, H.1
Klein, F.2
Scheid, J.F.3
Warncke, M.4
Pietzsch, J.5
Oliveira, T.Y.6
-
135
-
-
77953655567
-
Maturation pathways of cross-reactive HIV-1 neutralizing antibodies
-
Xiao X, Chen W, Feng Y, Dimitrov DS. Maturation pathways of cross-reactive HIV-1 neutralizing antibodies. Viruses (2009) 1(3):802-17. doi:10.3390/v1030802.
-
(2009)
Viruses
, vol.1
, Issue.3
, pp. 802-817
-
-
Xiao, X.1
Chen, W.2
Feng, Y.3
Dimitrov, D.S.4
-
136
-
-
84934937791
-
Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice
-
Dosenovic P, von Boehmer L, Escolano A, Jardine J, Freund NT, Gitlin AD, et al. Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice. Cell (2015) 161(7):1505-15. doi:10.1016/j.cell.2015.06.003.
-
(2015)
Cell
, vol.161
, Issue.7
, pp. 1505-1515
-
-
Dosenovic, P.1
von Boehmer, L.2
Escolano, A.3
Jardine, J.4
Freund, N.T.5
Gitlin, A.D.6
-
137
-
-
84990876450
-
HIV vaccine design to target germline precursors of glycan-dependent broadly neutralizing antibodies
-
Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, et al. HIV vaccine design to target germline precursors of glycan-dependent broadly neutralizing antibodies. Immunity (2016) 45(3):483-96. doi:10.1016/j.immuni.2016.08.016.
-
(2016)
Immunity
, vol.45
, Issue.3
, pp. 483-496
-
-
Steichen, J.M.1
Kulp, D.W.2
Tokatlian, T.3
Escolano, A.4
Dosenovic, P.5
Stanfield, R.L.6
-
138
-
-
84934954773
-
HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen
-
Jardine JG, Ota T, Sok D, Pauthner M, Kulp DW, Kalyuzhniy O, et al. HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen. Science (2015) 349(6244):156-61. doi:10.1126/science.aac5894.
-
(2015)
Science
, vol.349
, Issue.6244
, pp. 156-161
-
-
Jardine, J.G.1
Ota, T.2
Sok, D.3
Pauthner, M.4
Kulp, D.W.5
Kalyuzhniy, O.6
-
139
-
-
84962251178
-
HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen
-
Jardine JG, Kulp DW, Havenar-Daughton C, Sarkar A, Briney B, Sok D, et al. HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen. Science (2016) 351(6280):1458-63. doi:10.1126/science.aad9195.
-
(2016)
Science
, vol.351
, Issue.6280
, pp. 1458-1463
-
-
Jardine, J.G.1
Kulp, D.W.2
Havenar-Daughton, C.3
Sarkar, A.4
Briney, B.5
Sok, D.6
-
140
-
-
84986296891
-
Tailored immunogens direct affinity maturation toward HIV neutralizing antibodies
-
Briney B, Sok D, Jardine JG, Kulp DW, Skog P, Menis S, et al. Tailored immunogens direct affinity maturation toward HIV neutralizing antibodies. Cell (2016) 166(6):1459-1470e11. doi:10.1016/j.cell.2016.08.005.
-
(2016)
Cell
, vol.166
, Issue.6
, pp. 1459-1470
-
-
Briney, B.1
Sok, D.2
Jardine, J.G.3
Kulp, D.W.4
Skog, P.5
Menis, S.6
-
141
-
-
82755184131
-
Increasing the potency and breadth of an HIV antibody by using structure-based rational design
-
Diskin R, Scheid JF, Marcovecchio PM, West AP Jr, Klein F, Gao H, et al. Increasing the potency and breadth of an HIV antibody by using structure-based rational design. Science (2011) 334(6060):1289-93. doi:10.1126/science.1213782.
-
(2011)
Science
, vol.334
, Issue.6060
, pp. 1289-1293
-
-
Diskin, R.1
Scheid, J.F.2
Marcovecchio, P.M.3
West, A.P.4
Klein, F.5
Gao, H.6
-
142
-
-
84861374644
-
PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4
-
Falkowska E, Ramos A, Feng Y, Zhou T, Moquin S, Walker LM, et al. PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4. J Virol (2012) 86(8):4394-403. doi:10.1128/JVI.06973-11.
-
(2012)
J Virol
, vol.86
, Issue.8
, pp. 4394-4403
-
-
Falkowska, E.1
Ramos, A.2
Feng, Y.3
Zhou, T.4
Moquin, S.5
Walker, L.M.6
-
143
-
-
84860723906
-
Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design
-
Bonsignori M, Montefiori DC, Wu X, Chen X, Hwang KK, Tsao CY, et al. Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design. J Virol (2012) 86(8):4688-92. doi:10.1128/JVI.07163-11.
-
(2012)
J Virol
, vol.86
, Issue.8
, pp. 4688-4692
-
-
Bonsignori, M.1
Montefiori, D.C.2
Wu, X.3
Chen, X.4
Hwang, K.K.5
Tsao, C.Y.6
-
144
-
-
77957189612
-
Antibody 2G12 recognizes di-mannose equivalently in domain-and nondomain-exchanged forms but only binds the HIV-1 glycan shield if domain exchanged
-
Doores KJ, Fulton Z, Huber M, Wilson IA, Burton DR. Antibody 2G12 recognizes di-mannose equivalently in domain-and nondomain-exchanged forms but only binds the HIV-1 glycan shield if domain exchanged. J Virol (2010) 84(20):10690-9. doi:10.1128/JVI.01110-10.
-
(2010)
J Virol
, vol.84
, Issue.20
, pp. 10690-10699
-
-
Doores, K.J.1
Fulton, Z.2
Huber, M.3
Wilson, I.A.4
Burton, D.R.5
-
145
-
-
84907527916
-
Structural evolution of glycan recognition by a family of potent HIV antibodies
-
Garces F, Sok D, Kong L, McBride R, Kim HJ, Saye-Francisco KF, et al. Structural evolution of glycan recognition by a family of potent HIV antibodies. Cell (2014) 159(1):69-79. doi:10.1016/j.cell.2014.09.009.
-
(2014)
Cell
, vol.159
, Issue.1
, pp. 69-79
-
-
Garces, F.1
Sok, D.2
Kong, L.3
McBride, R.4
Kim, H.J.5
Saye-Francisco, K.F.6
-
146
-
-
84961392264
-
Neutralizing antibody affords comparable protection against vaginal and rectal simian/human immunodeficiency virus challenge in macaques
-
Moldt B, Le KM, Carnathan DG, Whitney JB, Schultz N, Lewis MG, et al. Neutralizing antibody affords comparable protection against vaginal and rectal simian/human immunodeficiency virus challenge in macaques. AIDS (2016) 30(10):1543-51. doi:10.1097/QAD.0000000000001102.
-
(2016)
AIDS
, vol.30
, Issue.10
, pp. 1543-1551
-
-
Moldt, B.1
Le, K.M.2
Carnathan, D.G.3
Whitney, J.B.4
Schultz, N.5
Lewis, M.G.6
-
147
-
-
84942811379
-
Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike
-
Lee JH, Leaman DP, Kim AS, Torrents de la Peña A, Sliepen K, Yasmeen A, et al. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nat Commun (2015) 6:8167. doi:10.1038/ncomms9167.
-
(2015)
Nat Commun
, vol.6
, pp. 8167
-
-
Lee, J.H.1
Leaman, D.P.2
Kim, A.S.3
Torrents de la Peña, A.4
Sliepen, K.5
Yasmeen, A.6
|