Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

Cell Reports

Volumn 7, Issue 3, 2014, Pages 785-795

  Scharf, Louise ^a   Scheid, Johannes F ^b   Lee, Jeong Hyun ^c   West, Anthony P ^a   Chen, Courtney ^a   Gao, Han ^a   Gnanapragasam, Priyanthi N P ^a   Mares, René ^a   Seaman, Michael S ^d   Ward, Andrew B ^c   Nussenzweig, Michel C ^b   Bjorkman, Pamela J ^a,e  

^a California Institute of Technology   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^e CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIBODY; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; IMMUNOGLOBULIN LIGHT CHAIN; NEUTRALIZING ANTIBODY; VIRUS ENVELOPE PROTEIN; EPITOPE; POLYSACCHARIDE; PROTEIN BINDING; 8ANC195 ANTIBODY; BROADLY NEUTRALIZING ANTIBODY; CD4 ANTIGEN; GLYCAN; GLYCOPROTEIN GP 41; UNCLASSIFIED DRUG;

ANTIBODY STRUCTURE; ARTICLE; BINDING SITE; CLONAL VARIATION; CRYSTAL STRUCTURE; ELECTRON MICROSCOPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; VIRUS ENVELOPE; VIRUS NEUTRALIZATION; VIRUS SPIKE; X RAY CRYSTALLOGRAPHY; CHEMISTRY; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULAR DYNAMICS; PROTEIN TERTIARY STRUCTURE; ANTIBODY COMBINING SITE; CONTROLLED STUDY; EMBRYO; HEAVY CHAIN; HUMAN CELL; PROTEIN FUNCTION; PROTEIN TARGETING;

ANTIBODIES, NEUTRALIZING; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; EPITOPES; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; MOLECULAR DYNAMICS SIMULATION; POLYSACCHARIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84899909771     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.04.001     Document Type: Article

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