Structural basis for germline antibody recognition of HIV-1 immunogens

eLife

Volumn 5, Issue MARCH2016, 2016, Pages

  Scharf, Louise ^a,d   West, Anthony P ^a   Sievers, Stuart A ^a,e   Chen, Courtney ^a   Jiang, Siduo ^a,f   Gao, Han ^a   Gray, Matthew D ^b   McGuire, Andrew T ^b   Scheid, Johannes F ^c   Nussenzweig, Michel C ^c   Stamatatos, Leonidas ^b   Bjorkman, Pamela J ^a  

^a California Institute of Technology   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d 23andMe ^*  (United States)

^e Kite Pharma   (United States)

^f D E SHAW RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY CHROMATOGRAPHY; ANTIGEN BINDING; ARTICLE; COMPARATIVE STUDY; CONCEPTUAL FRAMEWORK; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; GERMLINE MUTATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE SYSTEM; PROTEIN EXPRESSION; SEQUENCE ALIGNMENT; STATIC ELECTRICITY; STRUCTURAL GENE; X RAY CRYSTALLOGRAPHY; CHEMISTRY; IMMUNOLOGY; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION;

GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; NEUTRALIZING ANTIBODY; PROTEIN BINDING;

ANTIBODIES, NEUTRALIZING; CRYSTALLOGRAPHY, X-RAY; HIV ANTIBODIES; HIV ANTIGENS; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 84962253716     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.13783     Document Type: Article

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