Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

Science

Volumn 352, Issue 6287, 2016, Pages 828-833

  Kong, Rui ^a   Xu, Kai ^a   Zhou, Tongqing ^a   Acharya, Priyamvada ^a   Lemmin, Thomas ^b   Liu, Kevin ^a   Ozorowski, Gabriel ^c   Soto, Cinque ^a   Taft, Justin D ^a   Bailer, Robert T ^a   Cale, Evan M ^a   Chen, Lei ^a   Choi, Chang W ^a   Chuang, Gwo Yu ^a   Doria Rose, Nicole A ^a   Druz, Aliaksandr ^a   Georgiev, Ivelin S ^a   Gorman, Jason ^a   Huang, Jinghe ^a   Joyce, M Gordon ^a   Louder, Mark K ^a   Ma, Xiaochu ^d   McKee, Krisha ^a   O'Dell, Sijy ^a   Pancera, Marie ^a   Yang, Yongping ^a   Blanchard, Scott C ^e   Mothes, Walther ^d   Burton, Dennis R ^c,f   Koff, Wayne C ^g   Connors, Mark ^a   Ward, Andrew B ^c   Kwong, Peter D ^a   Mascola, John R ^a   more..

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^g INTERNATIONAL AIDS VACCINE INITIATIVE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLYCAN; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; HYBRID PROTEIN; NEUTRALIZING ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; PEPTIDE; VIRUS ANTIBODY; VIRUS FUSION PROTEIN;

ANTIBODY; CRYSTAL STRUCTURE; DISEASE TREATMENT; HUMAN IMMUNODEFICIENCY VIRUS; INHIBITION; LIGAND; PEPTIDE; VACCINE; VIRAL DISEASE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIBODY DETECTION; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; VIRUS ENTRY; VIRUS ENVELOPE; VIRUS NEUTRALIZATION; B LYMPHOCYTE; CHEMICAL PHENOMENA; CHEMISTRY; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; MOLECULAR GENETICS; PROTEIN CONFORMATION; ULTRASTRUCTURE; VIROLOGY; X RAY CRYSTALLOGRAPHY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AIDS VACCINES; AMINO ACID SEQUENCE; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; B-LYMPHOCYTES; CRYSTALLOGRAPHY, X-RAY; HIV ENVELOPE PROTEIN GP120; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMMUNODOMINANT EPITOPES; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN CONFORMATION; VIRAL FUSION PROTEINS; VIRUS INTERNALIZATION;

EID: 84969219469     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aae0474     Document Type: Article

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