Antibody 2G12 recognizes di-mannose equivalently in domain- and nondomain-exchanged forms but only binds the HIV-1 glycan shield if domain exchanged

Journal of Virology

Volumn 84, Issue 20, 2010, Pages 10690-10699

  Doores, Katie J ^a,b   Fulton, Zara ^a   Huber, Michael ^a,b   Wilson, Ian A ^a   Burton, Dennis R ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCAN; GLYCOCONJUGATE; GLYCOPROTEIN GP 120; MANNOSE; MONOCLONAL ANTIBODY 2G12;

AMINO ACID SUBSTITUTION; ANTIGEN BINDING; ARTICLE; BINDING SITE; CANDIDA ALBICANS; CONTROLLED STUDY; CRYSTALLOGRAPHY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION;

AIDS VACCINES; AMINO ACID SUBSTITUTION; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; GENETIC VARIATION; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; MODELS, MOLECULAR; OLIGOSACCHARIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY;

CANDIDA ALBICANS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 77957189612     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01110-10     Document Type: Article

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