Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo

Science

Volumn 352, Issue 6288, 2016, Pages 1001-1004

  Lu, Ching Lan ^a,b   Murakowski, Dariusz K ^c   Bournazos, Stylianos ^a   Schoofs, Till ^a   Sarkar, Debolina ^c   Halper Stromberg, Ariel ^a   Horwitz, Joshua A ^a   Nogueira, Lilian ^a   Golijanin, Jovana ^a   Gazumyan, Anna ^a   Ravetch, Jeffrey V ^a   Caskey, Marina ^a   Chakraborty, Arup K ^c,d   Nussenzweig, Michel C ^a,e  

^a ROCKEFELLER UNIVERSITY   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c Massachusetts Institute of Technology Cambridge   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BROADLY NEUTRALIZING ANTIBODY; FC GAMMA RECEPTOR IV; FC RECEPTOR; GLYCOPROTEIN; IMMUNOGLOBULIN G1; MONOCLONAL ANTIBODY 3BNC117; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS RNA; 3BNC117 ANTIBODY; HOMEODOMAIN PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; IL2RG PROTEIN, MOUSE; INTERLEUKIN 2 RECEPTOR GAMMA; RAG-1 PROTEIN;

ANTIBODY; DISEASE TREATMENT; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE RESPONSE; INFECTIVITY; REACTION KINETICS; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIBODY DEPENDENT CELLULAR PHAGOCYTOSIS; ANTIVIRAL ACTIVITY; ARTICLE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SURFACE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOTHERAPY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRAL CLEARANCE; VIRUS LOAD; VIRUS NEUTRALIZATION; ANIMAL; APOPTOSIS; CELL LINE; GENETICS; HIV INFECTIONS; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; MUTANT MOUSE STRAIN; NONOBESE DIABETIC MOUSE; PASSIVE IMMUNIZATION; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANIMALS; ANTIBODIES, NEUTRALIZING; APOPTOSIS; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; HIV ANTIBODIES; HIV INFECTIONS; HIV-1; HOMEODOMAIN PROTEINS; HUMANS; IMMUNIZATION, PASSIVE; IMMUNOSUPPRESSION; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; MICE; MICE, INBRED NOD; MICE, MUTANT STRAINS; RECEPTORS, IGG; VIRAL LOAD;

EID: 84966397893     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaf1279     Document Type: Article

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