Epigenetic strategies to reverse drug resistance in heterogeneous multiple myeloma

Clinical Epigenetics

Volumn 9, Issue 1, 2017, Pages

  Issa, Mark E ^a   Takhsha, Farnaz Sedigheh ^b   Chirumamilla, Chandra Sekhar ^b   Perez Novo, Claudina ^b   Vanden Berghe, Wim ^b   Cuendet, Muriel ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Combination therapy; Drug resistance; Epigenetic drugs; Microenvironment; Multiple myeloma; Stem cells; Treatment

Indexed keywords

6 (4 CHLOROPHENYL) N ETHYL 8 METHOXY 1 METHYL 4H [1,2,4]TRIAZOLO[4,3 A][1,4]BENZODIAZEPINE 4 ACETAMIDE; ABEXINOSTAT; BELINOSTAT; BORTEZOMIB; CD24 ANTIGEN; CD34 ANTIGEN; CYCLIN D; DEXAMETHASONE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; DOXORUBICIN; ENTINOSTAT; EVEROLIMUS; HISTONE DEACETYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; MICRORNA; MICRORNA 26A; MYC PROTEIN; PANOBINOSTAT; PROTEIN BCL 2; RICOLINOSTAT; TEFINOSTAT; THALIDOMIDE; TRANSCRIPTION FACTOR EZH2; VASCULOTROPIN A; VINCRISTINE; ANTINEOPLASTIC AGENT;

AUTOLOGOUS STEM CELL TRANSPLANTATION; CANCER RECURRENCE; CANCER STEM CELL; CANCER SURVIVAL; CELL DIFFERENTIATION; CELL EXPANSION; CELL FATE; CELL POPULATION; CELL PROLIFERATION; DIARRHEA; DOWN REGULATION; EPIGENETICS; GENE DELETION; GENE EXPRESSION; GENE MUTATION; HUMAN; LYMPHOCYTOPENIA; MALIGNANT TRANSFORMATION; MULTIPLE MYELOMA; NEUTROPENIA; NONHUMAN; PATHOGENESIS; PERIPHERAL NEUROPATHY; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PNEUMONIA; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVIEW; SIGNAL TRANSDUCTION; STEM CELL SELF-RENEWAL; THROMBOCYTOPENIA; TUMOR MICROENVIRONMENT; TUMOR SUPPRESSOR GENE; UPREGULATION; ANIMAL; DRUG EFFECTS; DRUG RESISTANCE; GENETIC EPIGENESIS; GENETICS; METABOLISM; MULTIDRUG RESISTANCE; PATHOLOGY;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; EPIGENESIS, GENETIC; HUMANS; MULTIPLE MYELOMA; NEOPLASTIC STEM CELLS; TUMOR MICROENVIRONMENT;

EID: 85011977704     PISSN: 18687075     EISSN: 18687083     Source Type: Journal    
DOI: 10.1186/s13148-017-0319-5     Document Type: Review

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