-
1
-
-
0033564902
-
DNA methylation
-
Singal R, Ginder GD. DNA methylation. Blood 1999, 93:4059-4070.
-
(1999)
Blood
, vol.93
, pp. 4059-4070
-
-
Singal, R.1
Ginder, G.D.2
-
2
-
-
0019198357
-
Mutagenic deamination of cytosine residues in DNA
-
Duncan BK,Miller JH.Mutagenic deamination of cytosine residues in DNA. Nature 1980, 287:560-561.
-
(1980)
Nature
, vol.287
, pp. 560-561
-
-
Duncan, B.K.1
Miller, J.H.2
-
5
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992, 69:915-926.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
6
-
-
37249012497
-
Histone acetylation and chromatin signature in stem cell identity and cancer
-
Shukla V, Vaissiere T, Herceg Z. Histone acetylation and chromatin signature in stem cell identity and cancer. Mutat Res 2008, 637:1-15.
-
(2008)
Mutat Res
, vol.637
, pp. 1-15
-
-
Shukla, V.1
Vaissiere, T.2
Herceg, Z.3
-
7
-
-
0003903126
-
-
New York: Springer-Verlag
-
van Holde K. Chromatin. New York: Springer-Verlag; 1989.
-
(1989)
Chromatin
-
-
van Holde, K.1
-
8
-
-
0242407193
-
Phylogenomics of the nucleosome
-
Malik HS, Henikoff S. Phylogenomics of the nucleosome. Nat Struct Biol 2003, 10:882-891.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 882-891
-
-
Malik, H.S.1
Henikoff, S.2
-
9
-
-
0035839136
-
Translating the histone code
-
Jenuwein T, Allis CD. Translating the histone code. Science 2001, 293:1074-1080.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
10
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl BD, Allis CD. The language of covalent histone modifications. Nature 2000, 403:41-45.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
11
-
-
0036532202
-
Histone methylation in transcriptional control
-
Kouzarides T. Histone methylation in transcriptional control. Curr Opin Genet Dev 2002, 12:198-209.
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 198-209
-
-
Kouzarides, T.1
-
12
-
-
0035883954
-
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails
-
Zhang Y, Reinberg D. Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails. Genes Dev 2001, 15:2343-2360.
-
(2001)
Genes Dev
, vol.15
, pp. 2343-2360
-
-
Zhang, Y.1
Reinberg, D.2
-
14
-
-
65349121777
-
Histone methylation and ubiquitination with their cross-talk and roles in gene expression and stability
-
Shukla A, Chaurasia P, Bhaumik SR. Histone methylation and ubiquitination with their cross-talk and roles in gene expression and stability. Cell Mol Life Sci 2008, 66:1419-1433.
-
(2008)
Cell Mol Life Sci
, vol.66
, pp. 1419-1433
-
-
Shukla, A.1
Chaurasia, P.2
Bhaumik, S.R.3
-
15
-
-
34447098370
-
A chromatin landmark and transcription initiation at most promoters in human cells
-
Guenther MG, Levine SS, Boyer LA, Jaenisch R, Young RA. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 2007, 130:77-88.
-
(2007)
Cell
, vol.130
, pp. 77-88
-
-
Guenther, M.G.1
Levine, S.S.2
Boyer, L.A.3
Jaenisch, R.4
Young, R.A.5
-
16
-
-
34547725157
-
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
-
Ooi SK, Qiu C, Bernstein E, et al. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature 2007, 448:714-717.
-
(2007)
Nature
, vol.448
, pp. 714-717
-
-
Ooi, S.K.1
Qiu, C.2
Bernstein, E.3
-
17
-
-
67349190247
-
Linking DNA methylation and histone modification: patterns and paradigms
-
Cedar H, Bergman Y. Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet 2009, 10:295-304.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 295-304
-
-
Cedar, H.1
Bergman, Y.2
-
18
-
-
0032572782
-
DNA methylation models histone acetylation
-
Eden S, Hashimshony T, Keshet I, Cedar H, Thorne AW. DNA methylation models histone acetylation. Nature 1998, 394:842.
-
(1998)
Nature
, vol.394
, pp. 842
-
-
Eden, S.1
Hashimshony, T.2
Keshet, I.3
Cedar, H.4
Thorne, A.W.5
-
19
-
-
0342437491
-
MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
-
Nan X, Campoy FJ, Bird A. MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 1997, 88:471-481.
-
(1997)
Cell
, vol.88
, pp. 471-481
-
-
Nan, X.1
Campoy, F.J.2
Bird, A.3
-
20
-
-
0348134871
-
Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer
-
Ballestar E, PazMF, Valle L, et al.Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer. EMBO J 2003, 22:6335-6345.
-
(2003)
EMBO J
, vol.22
, pp. 6335-6345
-
-
Ballestar, E.1
Paz, M.F.2
Valle, L.3
-
21
-
-
33846649587
-
Polycombmediated methylation on Lys27 of histone H3 premarks genes for de novo methylation in cancer
-
Schlesinger Y, Straussman R, Keshet I, et al. Polycombmediated methylation on Lys27 of histone H3 premarks genes for de novo methylation in cancer. Nat Genet 2007, 39:232-236.
-
(2007)
Nat Genet
, vol.39
, pp. 232-236
-
-
Schlesinger, Y.1
Straussman, R.2
Keshet, I.3
-
22
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007, 128:683-692.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
23
-
-
3042767202
-
MicroRNAs: small RNAs with a big role in gene regulation
-
He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 2004, 5:522-531.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
24
-
-
56949091982
-
MiRNAs epigenetics, and cancer
-
Rouhi A, Mager DL, Humphries RK, Kuchenbauer F. MiRNAs, epigenetics, and cancer. Mamm Genome 2008, 19:517-525.
-
(2008)
Mamm Genome
, vol.19
, pp. 517-525
-
-
Rouhi, A.1
Mager, D.L.2
Humphries, R.K.3
Kuchenbauer, F.4
-
25
-
-
33645321647
-
MicroRNAs in cell proliferation, cell death, and tumorigenesis
-
Hwang HW, Mendell JT. MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer 2006, 94:776-780.
-
(2006)
Br J Cancer
, vol.94
, pp. 776-780
-
-
Hwang, H.W.1
Mendell, J.T.2
-
26
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
27
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin GA, Dumitru CD, Shimizu M, et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 2002, 99:15524-15529.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
-
28
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin GA, Sevignani C, Dumitru CD, et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 2004, 101:2999-3004.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
-
29
-
-
22144461002
-
miRNAs, cancer, and stem cell division
-
Croce CM, Calin GA. miRNAs, cancer, and stem cell division. Cell 2005, 122:6-7.
-
(2005)
Cell
, vol.122
, pp. 6-7
-
-
Croce, C.M.1
Calin, G.A.2
-
30
-
-
33847763576
-
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
-
Lujambio A, Ropero S, Ballestar E, et al. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res 2007, 67:1424-1429.
-
(2007)
Cancer Res
, vol.67
, pp. 1424-1429
-
-
Lujambio, A.1
Ropero, S.2
Ballestar, E.3
-
31
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, et al. MicroRNA expression profiles classify human cancers. Nature 2005, 435:834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
-
32
-
-
24644472515
-
Antisense transcription in the mammalian transcriptome
-
Katayama S, Tomaru Y, Kasukawa T, et al. Antisense transcription in the mammalian transcriptome. Science 2005, 309:1564-1566.
-
(2005)
Science
, vol.309
, pp. 1564-1566
-
-
Katayama, S.1
Tomaru, Y.2
Kasukawa, T.3
-
33
-
-
38049155825
-
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
-
Yu W, Gius D, Onyango P, et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 2008, 451:202-206.
-
(2008)
Nature
, vol.451
, pp. 202-206
-
-
Yu, W.1
Gius, D.2
Onyango, P.3
-
34
-
-
0038581890
-
Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease
-
Tufarelli C, Stanley JA, Garrick D, et al. Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease. Nat Genet 2003, 34:157-165.
-
(2003)
Nat Genet
, vol.34
, pp. 157-165
-
-
Tufarelli, C.1
Stanley, J.A.2
Garrick, D.3
-
35
-
-
4344705509
-
Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern
-
Espada J, Ballestar E, Fraga MF, et al. Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern. J Biol Chem 2004, 279:37175-37184.
-
(2004)
J Biol Chem
, vol.279
, pp. 37175-37184
-
-
Espada, J.1
Ballestar, E.2
Fraga, M.F.3
-
36
-
-
0020699979
-
Hypomethylation distinguishes genes of some human cancers from their normal counterparts
-
Feinberg AP, Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 1983, 301:89-92.
-
(1983)
Nature
, vol.301
, pp. 89-92
-
-
Feinberg, A.P.1
Vogelstein, B.2
-
37
-
-
0034523641
-
Cytosine methylation and human cancer
-
Warnecke PM, Bestor TH. Cytosine methylation and human cancer. Curr Opin Oncol 2000, 12:68-73.
-
(2000)
Curr Opin Oncol
, vol.12
, pp. 68-73
-
-
Warnecke, P.M.1
Bestor, T.H.2
-
38
-
-
1042278765
-
The history of cancer epigenetics
-
Feinberg AP, Tycko B. The history of cancer epigenetics. Nat Rev Cancer 2004, 4:143-153.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 143-153
-
-
Feinberg, A.P.1
Tycko, B.2
-
39
-
-
0032846413
-
DNA methylation changes andmultiplemyeloma
-
Ng MH, Wong IH, Lo KW. DNA methylation changes andmultiplemyeloma. Leuk Lymphoma 1999, 34:463-472.
-
(1999)
Leuk Lymphoma
, vol.34
, pp. 463-472
-
-
Ng, M.H.1
Wong, I.H.2
Lo, K.W.3
-
40
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
Eden A, Gaudet F, Waghmare A, Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science 2003, 300:455.
-
(2003)
Science
, vol.300
, pp. 455
-
-
Eden, A.1
Gaudet, F.2
Waghmare, A.3
Jaenisch, R.4
-
41
-
-
23744461983
-
Transposons reanimated in mice
-
Bestor TH. Transposons reanimated in mice. Cell 2005, 122:322-325.
-
(2005)
Cell
, vol.122
, pp. 322-325
-
-
Bestor, T.H.1
-
42
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M. Epigenetics in cancer. N Engl J Med 2008, 358:1148-1159.
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
43
-
-
34447103363
-
The new frontier in cancer research: deciphering cancer epigenetics
-
Lohrum M, Stunnenberg HG, Logie C. The new frontier in cancer research: deciphering cancer epigenetics. Int J Biochem Cell Biol 2007, 39:1450-1461.
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 1450-1461
-
-
Lohrum, M.1
Stunnenberg, H.G.2
Logie, C.3
-
44
-
-
0024365892
-
Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
-
Greger V, Passarge E, Hopping W, Messmer E, Horsthemke B. Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum Genet 1989, 83:155-158.
-
(1989)
Hum Genet
, vol.83
, pp. 155-158
-
-
Greger, V.1
Passarge, E.2
Hopping, W.3
Messmer, E.4
Horsthemke, B.5
-
45
-
-
0033758812
-
Molecular aspects of multiple myeloma
-
Kastrinakis NG, Gorgoulis VG, Foukas PG, Dimopoulos MA, Kittas C. Molecular aspects of multiple myeloma. Ann Oncol 2000, 11:1217-1228.
-
(2000)
Ann Oncol
, vol.11
, pp. 1217-1228
-
-
Kastrinakis, N.G.1
Gorgoulis, V.G.2
Foukas, P.G.3
Dimopoulos, M.A.4
Kittas, C.5
-
46
-
-
34248647610
-
Multiple myeloma: a review of the epidemiologic literature
-
Alexander DD, Mink PJ, Adami HO, et al. Multiple myeloma: a review of the epidemiologic literature. Int J Cancer 2007, 120(Suppl. 12):40-61.
-
(2007)
Int J Cancer
, vol.120
, Issue.SUPPL. 12
, pp. 40-61
-
-
Alexander, D.D.1
Mink, P.J.2
Adami, H.O.3
-
47
-
-
2642532716
-
DNAmethylation analysis identifies the E-cadherin gene as a potential marker of disease progression in patients with monoclonal gammopathies
-
Seidl S, Ackermann J, Kaufmann H, et al. DNAmethylation analysis identifies the E-cadherin gene as a potential marker of disease progression in patients with monoclonal gammopathies. Cancer 2004, 100:2598-2606.
-
(2004)
Cancer
, vol.100
, pp. 2598-2606
-
-
Seidl, S.1
Ackermann, J.2
Kaufmann, H.3
-
48
-
-
0346025548
-
Disruption of INK4/CDK/Rb cell cycle pathway by gene hypermethylation in multiple myeloma and MGUS
-
Chim CS, Fung TK, Liang R. Disruption of INK4/CDK/Rb cell cycle pathway by gene hypermethylation in multiple myeloma and MGUS. Leukemia 2003, 17:2533-2535.
-
(2003)
Leukemia
, vol.17
, pp. 2533-2535
-
-
Chim, C.S.1
Fung, T.K.2
Liang, R.3
-
49
-
-
1042289347
-
Methylation profiling in multiple myeloma
-
Chim CS, Kwong YL, Fung TK, Liang R. Methylation profiling in multiple myeloma. Leuk Res 2004, 28:379-385.
-
(2004)
Leuk Res
, vol.28
, pp. 379-385
-
-
Chim, C.S.1
Kwong, Y.L.2
Fung, T.K.3
Liang, R.4
-
50
-
-
0034746509
-
Hypermethylation of p16INK4A gene promoter during the progression of plasma cell dyscrasia
-
Uchida T, Kinoshita T, Ohno T, Ohashi H, Nagai H, et al. Hypermethylation of p16INK4A gene promoter during the progression of plasma cell dyscrasia. Leukemia 2001, 15:157-165.
-
(2001)
Leukemia
, vol.15
, pp. 157-165
-
-
Uchida, T.1
Kinoshita, T.2
Ohno, T.3
Ohashi, H.4
Nagai, H.5
-
51
-
-
0037697734
-
Different prognostic values of p15(INK4b) and p16(INK4a) genemethylations inmultiplemyeloma
-
Guillerm G, Depil S, Wolowiec D, Quesnel B. Different prognostic values of p15(INK4b) and p16(INK4a) genemethylations inmultiplemyeloma. Haematologica 2003, 88:476-478.
-
(2003)
Haematologica
, vol.88
, pp. 476-478
-
-
Guillerm, G.1
Depil, S.2
Wolowiec, D.3
Quesnel, B.4
-
52
-
-
0035412365
-
p16(INK4a) and p15(INK4b) gene methylations in plasma cells from monoclonal gammopathy of undetermined significance
-
Guillerm G, Gyan E, Wolowiec D, et al. p16(INK4a) and p15(INK4b) gene methylations in plasma cells from monoclonal gammopathy of undetermined significance. Blood 2001, 98:244-246.
-
(2001)
Blood
, vol.98
, pp. 244-246
-
-
Guillerm, G.1
Gyan, E.2
Wolowiec, D.3
-
53
-
-
6344229983
-
DNA methylation changes in multiple myeloma
-
Galm O, Wilop S, Reichelt J, et al. DNA methylation changes in multiple myeloma. Leukemia 2004, 18:1687-1692.
-
(2004)
Leukemia
, vol.18
, pp. 1687-1692
-
-
Galm, O.1
Wilop, S.2
Reichelt, J.3
-
54
-
-
33747867011
-
Analysis of MTHFRpolymorphisms and P16 methylation and their correlation with clinical-biological features of multiple myeloma
-
Chiusolo P, Farina G, Putzulu R, et al. Analysis of MTHFRpolymorphisms and P16 methylation and their correlation with clinical-biological features of multiple myeloma. Ann Hematol 2006, 85:474-477.
-
(2006)
Ann Hematol
, vol.85
, pp. 474-477
-
-
Chiusolo, P.1
Farina, G.2
Putzulu, R.3
-
55
-
-
33846852215
-
Tumor suppressor p16 methylation in multiple myeloma: biological and clinical implications
-
Gonzalez-Paz N, Chng WJ, McClure RF, et al. Tumor suppressor p16 methylation in multiple myeloma: biological and clinical implications. Blood 2007, 109:1228-1232.
-
(2007)
Blood
, vol.109
, pp. 1228-1232
-
-
Gonzalez-Paz, N.1
Chng, W.J.2
McClure, R.F.3
-
56
-
-
18044390654
-
p16 gene methylation lacks correlation with angiogenesis and prognosis in multiple myeloma
-
Ribas C, Colleoni GW, Felix RS, et al. p16 gene methylation lacks correlation with angiogenesis and prognosis in multiple myeloma. Cancer Lett 2005, 222:247-254.
-
(2005)
Cancer Lett
, vol.222
, pp. 247-254
-
-
Ribas, C.1
Colleoni, G.W.2
Felix, R.S.3
-
57
-
-
18544379572
-
Methylation is an inactivating mechanism of the p16 gene in multiple myeloma associated with high plasma cell proliferation and short survival
-
Mateos MV, Garcia-Sanz R, Lopez-Perez R, et al. Methylation is an inactivating mechanism of the p16 gene in multiple myeloma associated with high plasma cell proliferation and short survival. Br J Haematol 2002, 118:1034-1040.
-
(2002)
Br J Haematol
, vol.118
, pp. 1034-1040
-
-
Mateos, M.V.1
Garcia-Sanz, R.2
Lopez-Perez, R.3
-
58
-
-
33846878522
-
Methylation and expression of the p16INK4A tumor suppressor gene in multiple myeloma
-
Dib A, Barlogie B, Shaughnessy JD, Kuehl WM, Jr. Methylation and expression of the p16INK4A tumor suppressor gene in multiple myeloma. Blood 2007, 109:1337-1338.
-
(2007)
Blood
, vol.109
, pp. 1337-1338
-
-
Dib, A.1
Barlogie, B.2
Shaughnessy, J.D.3
Kuehl Jr., W.M.4
-
59
-
-
33846425692
-
Aberrant gene methylation implicated in the progression of monoclonal gammopathy of undetermined significance to multiple myeloma
-
Chim CS, Liang R, Leung MH, Kwong YL. Aberrant gene methylation implicated in the progression of monoclonal gammopathy of undetermined significance to multiple myeloma. J Clin Pathol 2007, 60:104-106.
-
(2007)
J Clin Pathol
, vol.60
, pp. 104-106
-
-
Chim, C.S.1
Liang, R.2
Leung, M.H.3
Kwong, Y.L.4
-
60
-
-
30644466740
-
Methylation of the INK4A/ARF locus in blood mononuclear cells
-
Deligezer U, Erten N, Akisik EE, Dalay N.Methylation of the INK4A/ARF locus in blood mononuclear cells. Ann Hematol 2006, 85:102-107.
-
(2006)
Ann Hematol
, vol.85
, pp. 102-107
-
-
Deligezer, U.1
Erten, N.2
Akisik, E.E.3
Dalay, N.4
-
61
-
-
0038691851
-
Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway
-
Lavelle D, DeSimone J, Hankewych M, Kousnetzova T, Chen YH. Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway. Leuk Res 2003, 27:999-1007.
-
(2003)
Leuk Res
, vol.27
, pp. 999-1007
-
-
Lavelle, D.1
DeSimone, J.2
Hankewych, M.3
Kousnetzova, T.4
Chen, Y.H.5
-
62
-
-
0034896438
-
Frequent deathassociated protein kinase promoter hypermethylation in multiple myeloma
-
Ng MH, To KW, Lo KW, et al. Frequent deathassociated protein kinase promoter hypermethylation in multiple myeloma. Clin Cancer Res 2001, 7:1724-1729.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1724-1729
-
-
Ng, M.H.1
To, K.W.2
Lo, K.W.3
-
63
-
-
34250827855
-
Epigenetic dysregulation of the death-associated protein kinase/p14/HDM2/p53/Apaf-1 apoptosis pathway in multiple myeloma
-
Chim CS, Liang R, Fung TK, Choi CL, Kwong YL. Epigenetic dysregulation of the death-associated protein kinase/p14/HDM2/p53/Apaf-1 apoptosis pathway in multiple myeloma. J Clin Pathol 2007, 60:664-669.
-
(2007)
J Clin Pathol
, vol.60
, pp. 664-669
-
-
Chim, C.S.1
Liang, R.2
Fung, T.K.3
Choi, C.L.4
Kwong, Y.L.5
-
64
-
-
2942584857
-
SOCS1 and SHP1 hypermethylation in multiple myeloma: implications for epigenetic activation of the Jak/STAT pathway
-
Chim CS, Fung TK, Cheung WC, Liang R, Kwong YL. SOCS1 and SHP1 hypermethylation in multiple myeloma: implications for epigenetic activation of the Jak/STAT pathway. Blood 2004, 103:4630-4635.
-
(2004)
Blood
, vol.103
, pp. 4630-4635
-
-
Chim, C.S.1
Fung, T.K.2
Cheung, W.C.3
Liang, R.4
Kwong, Y.L.5
-
65
-
-
0038784365
-
SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma
-
Galm O, Yoshikawa H, Esteller M, Osieka R, Herman JG. SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma. Blood 2003, 101:2784-2788.
-
(2003)
Blood
, vol.101
, pp. 2784-2788
-
-
Galm, O.1
Yoshikawa, H.2
Esteller, M.3
Osieka, R.4
Herman, J.G.5
-
66
-
-
0041525763
-
SOCS-1 gene methylation is frequent but does not appear to have prognostic value in patients with multiple myeloma
-
Depil S, Saudemont A, Quesnel B. SOCS-1 gene methylation is frequent but does not appear to have prognostic value in patients with multiple myeloma. Leukemia 2003, 17:1678-1679.
-
(2003)
Leukemia
, vol.17
, pp. 1678-1679
-
-
Depil, S.1
Saudemont, A.2
Quesnel, B.3
-
67
-
-
19944432663
-
Differential methylation of genes that regulate cytokine signaling in lymphoid and hematopoietic tumors
-
Reddy J, ShivapurkarN, Takahashi T, et al.Differential methylation of genes that regulate cytokine signaling in lymphoid and hematopoietic tumors. Oncogene 2005, 24:732-736.
-
(2005)
Oncogene
, vol.24
, pp. 732-736
-
-
Reddy, J.1
Shivapurkar, N.2
Takahashi, T.3
-
68
-
-
28544442914
-
Infrequent epigenetic dysregulation of CIP/KIP family of cyclindependent kinase inhibitors in multiple myeloma
-
Chim CS, Liang R, Fung TK, Kwong YL. Infrequent epigenetic dysregulation of CIP/KIP family of cyclindependent kinase inhibitors in multiple myeloma. Leukemia 2005, 19:2352-2355.
-
(2005)
Leukemia
, vol.19
, pp. 2352-2355
-
-
Chim, C.S.1
Liang, R.2
Fung, T.K.3
Kwong, Y.L.4
-
69
-
-
33748861305
-
High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma
-
Song YF, Xu R, Zhang XH, et al. High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma. J Clin Pathol 2006, 59:947-951.
-
(2006)
J Clin Pathol
, vol.59
, pp. 947-951
-
-
Song, Y.F.1
Xu, R.2
Zhang, X.H.3
-
70
-
-
33751099815
-
Reversal of p53 epigenetic silencing in multiple myeloma permits apoptosis by a p53 activator
-
Hurt EM, Thomas SB, Peng B, Farrar WL. Reversal of p53 epigenetic silencing in multiple myeloma permits apoptosis by a p53 activator. Cancer Biol Ther 2006, 5:1154-1160.
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 1154-1160
-
-
Hurt, E.M.1
Thomas, S.B.2
Peng, B.3
Farrar, W.L.4
-
71
-
-
28044455426
-
Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with multiple myeloma
-
Takada S, Morita K, Hayashi K, et al.Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with multiple myeloma. Eur J Haematol 2005, 75:505-510.
-
(2005)
Eur J Haematol
, vol.75
, pp. 505-510
-
-
Takada, S.1
Morita, K.2
Hayashi, K.3
-
72
-
-
34347262494
-
Down-regulation of PU 1 by methylation of distal regulatory elements and the promoter is required for myeloma cell growth
-
Tatetsu H, Ueno S, Hata H, et al. Down-regulation of PU.1 by methylation of distal regulatory elements and the promoter is required for myeloma cell growth. Cancer Res 2007, 67:5328-5336.
-
(2007)
Cancer Res
, vol.67
, pp. 5328-5336
-
-
Tatetsu, H.1
Ueno, S.2
Hata, H.3
-
73
-
-
33845261204
-
ABCG2 expression, function, and promoter methylation in human multiple myeloma
-
Turner JG, Gump JL, Zhang C, et al. ABCG2 expression, function, and promoter methylation in human multiple myeloma. Blood 2006, 108:3881-3889.
-
(2006)
Blood
, vol.108
, pp. 3881-3889
-
-
Turner, J.G.1
Gump, J.L.2
Zhang, C.3
-
74
-
-
20244368980
-
Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours
-
Murai M, Toyota M, Satoh A. et al. Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours. Br J Cancer 2005, 92:1165-1172.
-
(2005)
Br J Cancer
, vol.92
, pp. 1165-1172
-
-
Murai, M.1
Toyota, M.2
Satoh, A.3
-
75
-
-
7944230299
-
Sp17 gene expression in myeloma cells is regulated by promoter methylation
-
Wang Z, Zhang Y, Ramsahoye B, Bowen D, Lim SH. Sp17 gene expression in myeloma cells is regulated by promoter methylation. Br J Cancer 2004, 91:1597-1603.
-
(2004)
Br J Cancer
, vol.91
, pp. 1597-1603
-
-
Wang, Z.1
Zhang, Y.2
Ramsahoye, B.3
Bowen, D.4
Lim, S.H.5
-
76
-
-
33644552738
-
SPAN-Xb expression in myeloma cells is dependent on promoter hypomethylation and can be upregulated pharmacologically
-
Wang Z, Zhang J, Zhang Y, Lim SH. SPAN-Xb expression in myeloma cells is dependent on promoter hypomethylation and can be upregulated pharmacologically. Int J Cancer 2006, 118:1436-1444.
-
(2006)
Int J Cancer
, vol.118
, pp. 1436-1444
-
-
Wang, Z.1
Zhang, J.2
Zhang, Y.3
Lim, S.H.4
-
77
-
-
14244259066
-
Epigenetic silencing of the human nucleotide excision repair gene, hHR23B, in interleukin-6-responsivemultiplemyeloma KAS-6/1 cells
-
Peng B, Hodge DR, Thomas SB, et al. Epigenetic silencing of the human nucleotide excision repair gene, hHR23B, in interleukin-6-responsivemultiplemyeloma KAS-6/1 cells. J Biol Chem 2005, 280:4182-4187.
-
(2005)
J Biol Chem
, vol.280
, pp. 4182-4187
-
-
Peng, B.1
Hodge, D.R.2
Thomas, S.B.3
-
78
-
-
38449108245
-
DNA hypermethylation and partial gene silencing of human thymine-DNA glycosylase in multiple myeloma cell lines
-
Peng B, Hurt EM, Hodge DR, Thomas SB, Farrar WL. DNA hypermethylation and partial gene silencing of human thymine-DNA glycosylase in multiple myeloma cell lines. Epigenetics 2006, 1:138-145.
-
(2006)
Epigenetics
, vol.1
, pp. 138-145
-
-
Peng, B.1
Hurt, E.M.2
Hodge, D.R.3
Thomas, S.B.4
Farrar, W.L.5
-
79
-
-
33745199379
-
hMLH1 and MGMT inactivation as a mechanism of tumorigenesis in monoclonal gammopathies
-
Martin P, Santon A, Garcia-CosioM, Bellas C. hMLH1 and MGMT inactivation as a mechanism of tumorigenesis in monoclonal gammopathies. Mod Pathol 2006, 19:914-921.
-
(2006)
Mod Pathol
, vol.19
, pp. 914-921
-
-
Martin, P.1
Santon, A.2
Garcia-Cosio, M.3
Bellas, C.4
-
80
-
-
36349013133
-
Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma
-
Chim CS, Pang R, Fung TK, Choi CL, Liang R. Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma. Leukemia 2007, 21:2527-2536.
-
(2007)
Leukemia
, vol.21
, pp. 2527-2536
-
-
Chim, C.S.1
Pang, R.2
Fung, T.K.3
Choi, C.L.4
Liang, R.5
-
81
-
-
25144453808
-
Epigenetic silencing of manganese superoxide dismutase (SOD-2) in KAS 6/1 human multiple myeloma cells increases cell proliferation
-
Hodge DR, Peng B, Pompeia C, et al. Epigenetic silencing of manganese superoxide dismutase (SOD-2) in KAS 6/1 human multiple myeloma cells increases cell proliferation. Cancer Biol Ther 2005, 4:585-592.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 585-592
-
-
Hodge, D.R.1
Peng, B.2
Pompeia, C.3
-
82
-
-
31544459798
-
Promoter hypermethylation of tetraspanin members contributes to their silencing in myeloma cell lines
-
Drucker L, Tohami T, Tartakover-Matalon S, et al. Promoter hypermethylation of tetraspanin members contributes to their silencing in myeloma cell lines. Carcinogenesis 2006, 27:197-204.
-
(2006)
Carcinogenesis
, vol.27
, pp. 197-204
-
-
Drucker, L.1
Tohami, T.2
Tartakover-Matalon, S.3
-
83
-
-
9444269817
-
Overexpression of the NOTCH ligand JAG2 in malignant plasma cells from multiple myeloma patients and cell lines
-
Houde C, Li Y, Song L, et al. Overexpression of the NOTCH ligand JAG2 in malignant plasma cells from multiple myeloma patients and cell lines. Blood 2004, 104:3697-3704.
-
(2004)
Blood
, vol.104
, pp. 3697-3704
-
-
Houde, C.1
Li, Y.2
Song, L.3
-
84
-
-
0035947602
-
Recombinant human DNA (cytosine-5) methyltransferase. III. Allosteric control, reaction order, and influence of plasmid topology and triplet repeat length on methylation of the fragile X CGG. CCG sequence
-
Bacolla A, Pradhan S, Larson JE, Roberts RJ, Wells RD. Recombinant human DNA (cytosine-5) methyltransferase. III. Allosteric control, reaction order, and influence of plasmid topology and triplet repeat length on methylation of the fragile X CGG.CCG sequence. J Biol Chem 2001, 276:18605-18613.
-
(2001)
J Biol Chem
, vol.276
, pp. 18605-18613
-
-
Bacolla, A.1
Pradhan, S.2
Larson, J.E.3
Roberts, R.J.4
Wells, R.D.5
-
85
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999, 99:247-257.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
86
-
-
19644389279
-
Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation
-
Hodge DR, Peng B, Cherry JC, et al. Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation. Cancer Res 2005, 65:4673-4682.
-
(2005)
Cancer Res
, vol.65
, pp. 4673-4682
-
-
Hodge, D.R.1
Peng, B.2
Cherry, J.C.3
-
87
-
-
34250767283
-
5-Azacytidine, a DNA methyltransferase inhibitor, induces ATRmediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib againstmultiplemyeloma cells
-
Kiziltepe T,Hideshima T, Catley L, et al. 5-Azacytidine, a DNA methyltransferase inhibitor, induces ATRmediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib againstmultiplemyeloma cells. Mol Cancer Ther 2007, 6:1718-1727.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1718-1727
-
-
Kiziltepe, T.1
Hideshima, T.2
Catley, L.3
-
88
-
-
39149102515
-
Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells
-
Heller G, Schmidt WM, Ziegler B, et al. Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells. Cancer Res 2008, 68:44-54.
-
(2008)
Cancer Res
, vol.68
, pp. 44-54
-
-
Heller, G.1
Schmidt, W.M.2
Ziegler, B.3
-
89
-
-
10744233452
-
Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies
-
Issa JP, Garcia-Manero G, Giles FJ, et al. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies. Blood 2004, 103:1635-1640.
-
(2004)
Blood
, vol.103
, pp. 1635-1640
-
-
Issa, J.P.1
Garcia-Manero, G.2
Giles, F.J.3
-
90
-
-
46749153406
-
An integrative genomic and epigenomic approach for the study of transcriptional regulation
-
Figueroa ME, Reimers M, Thompson RF, et al. An integrative genomic and epigenomic approach for the study of transcriptional regulation. PLoS One 2008, 3:e1882.
-
(2008)
PLoS One
, vol.3
-
-
Figueroa, M.E.1
Reimers, M.2
Thompson, R.F.3
-
91
-
-
70350720044
-
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation
-
Figueroa ME, Skrabanek L, Li Y, et al. MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation. Blood 2009, 114:3448-3458.
-
(2009)
Blood
, vol.114
, pp. 3448-3458
-
-
Figueroa, M.E.1
Skrabanek, L.2
Li, Y.3
-
92
-
-
2442674336
-
Microarray analysis of epigenetic silencing of gene expression in the KAS-6/1 multiple myeloma cell line
-
Pompeia C, Hodge DR, Plass C, et al. Microarray analysis of epigenetic silencing of gene expression in the KAS-6/1 multiple myeloma cell line. Cancer Res 2004, 64:3465-3473.
-
(2004)
Cancer Res
, vol.64
, pp. 3465-3473
-
-
Pompeia, C.1
Hodge, D.R.2
Plass, C.3
-
93
-
-
69749092741
-
High definition profiling ofmammalianDNAmethylation by array capture and single molecule bisulfite sequencing
-
Hodges E, Smith AD, Kendall J, et al. High definition profiling ofmammalianDNAmethylation by array capture and single molecule bisulfite sequencing. Genome Res 2009, 19:1593-1605.
-
(2009)
Genome Res
, vol.19
, pp. 1593-1605
-
-
Hodges, E.1
Smith, A.D.2
Kendall, J.3
-
94
-
-
23044514626
-
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
-
Weber M, Davies JJ, Wittig D et al. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat Genet 2005, 37:853-862.
-
(2005)
Nat Genet
, vol.37
, pp. 853-862
-
-
Weber, M.1
Davies, J.J.2
Wittig, D...3
-
95
-
-
43149098062
-
Comprehensive high-throughput arrays for relativemethylation (CHARM)
-
Irizarry RA, Ladd-Acosta C, Carvalho B, et al. Comprehensive high-throughput arrays for relativemethylation (CHARM). Genome Res 2008, 18:780-790.
-
(2008)
Genome Res
, vol.18
, pp. 780-790
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Carvalho, B.3
-
96
-
-
33746756014
-
Comparative isoschizomer profiling of cytosine methylation: the HELP assay
-
Khulan B, Thompson RF, Ye K, et al. Comparative isoschizomer profiling of cytosine methylation: the HELP assay. Genome Res 2006, 16:1046-1055.
-
(2006)
Genome Res
, vol.16
, pp. 1046-1055
-
-
Khulan, B.1
Thompson, R.F.2
Ye, K.3
-
97
-
-
63849197532
-
Genomewide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/Tlymphoid features
-
Figueroa ME,Wouters BJ, Skrabanek L, et al. Genomewide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/Tlymphoid features. Blood 2009, 113:2795-2804.
-
(2009)
Blood
, vol.113
, pp. 2795-2804
-
-
Figueroa, M.E.1
Wouters, B.J.2
Skrabanek, L.3
-
98
-
-
64349091471
-
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells
-
Ball MP, Li JB, Gao Y, et al. Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nat Biotechnol 2009, 27:361-368.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 361-368
-
-
Ball, M.P.1
Li, J.B.2
Gao, Y.3
-
99
-
-
52049103600
-
Meta-analysis of microarray studies reveals a novel hematopoietic progenitor cell signature and demonstrates feasibility of inter-platform data integration
-
Sohal D, Yeatts A, Ye K, et al. Meta-analysis of microarray studies reveals a novel hematopoietic progenitor cell signature and demonstrates feasibility of inter-platform data integration. PLoS One 2008, 3:e2965.
-
(2008)
PLoS One
, vol.3
-
-
Sohal, D.1
Yeatts, A.2
Ye, K.3
|