Unabridged analysis of human histone H3 by differential top-down mass spectrometry reveals hypermethylated proteoforms from MMSET/NSD2 overexpression

Molecular and Cellular Proteomics

Volumn 15, Issue 3, 2016, Pages 776-790

  Zheng, Yupeng ^a   Fornelli, Luca ^a   Compton, Philip D ^a   Sharma, Seema ^b   Canterbury, Jesse ^b   Mullen, Christopher ^a   Zabrouskov, Vlad ^b   Fellers, Ryan T ^a   Thomas, Paul M ^a   Licht, Jonathan D ^c   Senko, Michael W ^b   Kelleher, Neil L ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Thermo Fisher Scientific   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; HISTONE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE MMSET; UNCLASSIFIED DRUG; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; LYSINE; PROTEOME; REPRESSOR PROTEIN; WHSC1 PROTEIN, HUMAN;

ARTICLE; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DISSOCIATION; ELECTRON; GENE OVEREXPRESSION; HISTONE ACETYLATION; HISTONE METHYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MULTIPLE MYELOMA CELL LINE; PRIORITY JOURNAL; TOP DOWN MASS SPECTROMETRY; COMPARATIVE STUDY; GENETIC EPIGENESIS; GENETICS; METABOLISM; METHYLATION; MULTIPLE MYELOMA; PROCEDURES; TUMOR CELL LINE; UPREGULATION;

CELL LINE, TUMOR; EPIGENESIS, GENETIC; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; LYSINE; MASS SPECTROMETRY; METHYLATION; MULTIPLE MYELOMA; PROTEOME; REPRESSOR PROTEINS; UP-REGULATION;

EID: 84962482309     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M115.053819     Document Type: Article

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