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Volumn 9, Issue 11, 2014, Pages 1511-1520

Dysregulated Class I histone deacetylases are indicators of poor prognosis in multiple myeloma

Author keywords

Class I HDAC; HDAC expression; Hematological malignancy; Histone deacetylases; Multiple myeloma; Prognosis

Indexed keywords

HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE 8; HDAC1 PROTEIN, HUMAN; HDAC6 PROTEIN, HUMAN; HISTONE DEACETYLASE;

EID: 84922055953     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/15592294.2014.983367     Document Type: Article
Times cited : (140)

References (53)
  • 3
    • 84860219443 scopus 로고    scopus 로고
    • The genetic architecture of multiple myeloma
    • PMID:22495321
    • Morgan GJ, Walker BA, Davies FE. The genetic architecture of multiple myeloma. Nat Rev Cancer 2012; 12:335-48; PMID:22495321; http://dx.doi.org/ 10.1038/nrc3257
    • (2012) Nat Rev Cancer , vol.12 , pp. 335-348
    • Morgan, G.J.1    Walker, B.A.2    Davies, F.E.3
  • 4
    • 33745259948 scopus 로고    scopus 로고
    • Early genetic events provide the basis for a clinical classification of multiple myeloma
    • PMID:16304402
    • Kuehl WM, Bergsagel PL. Early genetic events provide the basis for a clinical classification of multiple myeloma. Hematol Am Soc Hematol Educ Prog 2005:346- 52; PMID:16304402; http://dx.doi.org/10.1182/ asheducation-2005.1.346
    • (2005) Hematol Am Soc Hematol Educ Prog , pp. 346-352
    • Kuehl, W.M.1    Bergsagel, P.L.2
  • 5
    • 27244445489 scopus 로고    scopus 로고
    • Molecular pathogenesis and a consequent classification of multiple myeloma
    • PMID:16155016
    • Bergsagel PL, Kuehl WM. Molecular pathogenesis and a consequent classification of multiple myeloma. J Clin Oncol 2005; 23:6333-8; PMID:16155016; http://dx. doi.org/10.1200/JCO.2005.05.021
    • (2005) J Clin Oncol , vol.23 , pp. 6333-6338
    • Bergsagel, P.L.1    Kuehl, W.M.2
  • 7
    • 57749170458 scopus 로고    scopus 로고
    • The many roles of histone deacetylases in development and physiology: Implications for disease and therapy
    • PMID:19065135
    • Haberland M, Montgomery RL, Olson EN. The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev 2009; 10:32-42; PMID:19065135; http://dx.doi.org/ 10.1038/nrg2485
    • (2009) Nat Rev , vol.10 , pp. 32-42
    • Haberland, M.1    Montgomery, R.L.2    Olson, E.N.3
  • 8
    • 61849144810 scopus 로고    scopus 로고
    • HDAC family: What are the cancer relevant targets?
    • PMID:18824292
    • Witt O, Deubzer HE, Milde T, Oehme I. HDAC family: What are the cancer relevant targets? Cancer Lett 2009; 277:8-21; PMID:18824292; http://dx.doi.org/ 10.1016/j.canlet.2008.08.016
    • (2009) Cancer Lett , vol.277 , pp. 8-21
    • Witt, O.1    Deubzer, H.E.2    Milde, T.3    Oehme, I.4
  • 9
    • 67349160499 scopus 로고    scopus 로고
    • HDAC expression and clinical prognosis in human malignancies
    • PMID:19103471
    • Weichert W. HDAC expression and clinical prognosis in human malignancies. Cancer Lett 2009; 280:168- 76; PMID:19103471; http://dx.doi.org/10.1016/j. canlet.2008.10.047
    • (2009) Cancer Lett , vol.280 , pp. 168-176
    • Weichert, W.1
  • 10
    • 37049001617 scopus 로고    scopus 로고
    • Clinical significance of histone deacetylase 1 expression in patients with hepatocellular carcinoma
    • PMID:18004079
    • Rikimaru T, Taketomi A, Yamashita Y, Shirabe K, Hamatsu T, Shimada M, Maehara Y. Clinical significance of histone deacetylase 1 expression in patients with hepatocellular carcinoma. Oncology 2007; 72:69- 74; PMID:18004079; http://dx.doi.org/10.1159/ 000111106
    • (2007) Oncology , vol.72 , pp. 69-74
    • Rikimaru, T.1    Taketomi, A.2    Yamashita, Y.3    Shirabe, K.4    Hamatsu, T.5    Shimada, M.6    Maehara, Y.7
  • 11
    • 50949104573 scopus 로고    scopus 로고
    • Expression of class I histone deacetylases indicates poor prognosis in endometrioid subtypes of ovarian and endometrial carcinomas
    • PMID:18714364
    • Weichert W, Denkert C, Noske A, Darb-Esfahani S, Dietel M, Kalloger SE, Huntsman DG, Kobel M. Expression of class I histone deacetylases indicates poor prognosis in endometrioid subtypes of ovarian and endometrial carcinomas. Neoplasia (New York, NY) 2008; 10:1021-7; PMID:18714364
    • (2008) Neoplasia (New York, NY) , vol.10 , pp. 1021-1027
    • Weichert, W.1    Denkert, C.2    Noske, A.3    Darb-Esfahani, S.4    Dietel, M.5    Kalloger, S.E.6    Huntsman, D.G.7    Kobel, M.8
  • 12
    • 38549157208 scopus 로고    scopus 로고
    • Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: A retrospective analysis
    • PMID:18207460
    • Weichert W, Roske A, Gekeler V, Beckers T, Ebert MP, Pross M, Dietel M, Denkert C, Rocken C. Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis. Lancet Oncol 2008; 9:139-48; PMID:18207460; http://dx.doi.org/10.1016/S1470- 2045(08)70004-4
    • (2008) Lancet Oncol , vol.9 , pp. 139-148
    • Weichert, W.1    Roske, A.2    Gekeler, V.3    Beckers, T.4    Ebert, M.P.5    Pross, M.6    Dietel, M.7    Denkert, C.8    Rocken, C.9
  • 13
    • 38949086502 scopus 로고    scopus 로고
    • Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy
    • PMID:18212746
    • Weichert W, Roske A, Gekeler V, Beckers T, Stephan C, Jung K, Fritzsche FR, Niesporek S, Denkert C, Dietel M, et al. Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy. Br J Cancer 2008; 98:604-10; PMID:18212746; http://dx.doi.org/10.1038/sj. bjc.6604199
    • (2008) Br J Cancer , vol.98 , pp. 604-610
    • Weichert, W.1    Roske, A.2    Gekeler, V.3    Beckers, T.4    Stephan, C.5    Jung, K.6    Fritzsche, F.R.7    Niesporek, S.8    Denkert, C.9    Dietel, M.10
  • 14
    • 41549159879 scopus 로고    scopus 로고
    • Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: Specific role of class I histone deacetylases in vitro and in vivo
    • PMID:18347167
    • Weichert W, Roske A, Niesporek S, Noske A, Buckendahl AC, Dietel M, Gekeler V, Boehm M, Beckers T, Denkert C. Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo. Clin Cancer Res 2008; 14:1669-77; PMID:18347167; http://dx.doi.org/10.1158/1078- 0432.CCR-07-0990
    • (2008) Clin Cancer Res , vol.14 , pp. 1669-1677
    • Weichert, W.1    Roske, A.2    Niesporek, S.3    Noske, A.4    Buckendahl, A.C.5    Dietel, M.6    Gekeler, V.7    Boehm, M.8    Beckers, T.9    Denkert, C.10
  • 15
    • 3042540199 scopus 로고    scopus 로고
    • Prediction of prognosis of estrogen receptor- positive breast cancer with combination of selected estrogen-regulated genes
    • PMID:15182430
    • Yoshida N, Omoto Y, Inoue A, Eguchi H, Kobayashi Y, Kurosumi M, Saji S, Suemasu K, Okazaki T, Nakachi K, et al. Prediction of prognosis of estrogen receptor- positive breast cancer with combination of selected estrogen-regulated genes. Cancer Sci 2004; 95:496- 502; PMID:15182430; http://dx.doi.org/10.1111/ j.1349-7006.2004.tb03239.x
    • (2004) Cancer Sci , vol.95 , pp. 496-502
    • Yoshida, N.1    Omoto, Y.2    Inoue, A.3    Eguchi, H.4    Kobayashi, Y.5    Kurosumi, M.6    Saji, S.7    Suemasu, K.8    Okazaki, T.9    Nakachi, K.10
  • 17
    • 50049108874 scopus 로고    scopus 로고
    • Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma
    • PMID:18671804
    • Marquard L, Gjerdrum LM, Christensen IJ, Jensen PB, Sehested M, Ralfkiaer E. Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma. Histopathology 2008; 53:267-77; PMID:18671804; http:// dx.doi.org/10.1111/j.1365-2559.2008.03109.x
    • (2008) Histopathology , vol.53 , pp. 267-277
    • Marquard, L.1    Gjerdrum, L.M.2    Christensen, I.J.3    Jensen, P.B.4    Sehested, M.5    Ralfkiaer, E.6
  • 18
    • 84855464431 scopus 로고    scopus 로고
    • Increased gene expression of histone deacetylases in patients with Philadelphia-negative chronic myeloproliferative neoplasms
    • PMID:21806350
    • Skov V, Larsen TS, Thomassen M, Riley CH, Jensen MK, Bjerrum OW, Kruse TA, Hasselbalch HC. Increased gene expression of histone deacetylases in patients with Philadelphia-negative chronic myeloproliferative neoplasms. Leuk Lymphoma 2012; 53:123-9; PMID:21806350; http://dx.doi.org/10.3109/ 10428194.2011.597905
    • (2012) Leuk Lymphoma , vol.53 , pp. 123-129
    • Skov, V.1    Larsen, T.S.2    Thomassen, M.3    Riley, C.H.4    Jensen, M.K.5    Bjerrum, O.W.6    Kruse, T.A.7    Hasselbalch, H.C.8
  • 19
    • 57449114002 scopus 로고    scopus 로고
    • Enhanced histone deacetylase enzyme activity in primary myelofibrosis
    • PMID:19052980
    • Wang JC, Chen C, Dumlao T, Naik S, Chang T, Xiao YY, Sominsky I, Burton J. Enhanced histone deacetylase enzyme activity in primary myelofibrosis. Leuk Lymphoma 2008; 49:2321-7; PMID:19052980; http://dx.doi.org/10.1080/10428190802527699
    • (2008) Leuk Lymphoma , vol.49 , pp. 2321-2327
    • Wang, J.C.1    Chen, C.2    Dumlao, T.3    Naik, S.4    Chang, T.5    Xiao, Y.Y.6    Sominsky, I.7    Burton, J.8
  • 21
    • 17144412566 scopus 로고    scopus 로고
    • Clinical significance of enhancer of zeste homolog 2 expression in colorectal cancer cases
    • PMID:15837043
    • Mimori K, Ogawa K, Okamoto M, Sudo T, Inoue H, Mori M. Clinical significance of enhancer of zeste homolog 2 expression in colorectal cancer cases. Eur J Surg Oncol 2005; 31:376-80; PMID:15837043; http://dx.doi.org/10.1016/j.ejso.2004.11.001
    • (2005) Eur J Surg Oncol , vol.31 , pp. 376-380
    • Mimori, K.1    Ogawa, K.2    Okamoto, M.3    Sudo, T.4    Inoue, H.5    Mori, M.6
  • 23
    • 84870750886 scopus 로고    scopus 로고
    • HDAC isoenzyme expression is deregulated in chronic lymphocytic leukemia B-cells and has a complex prognostic significance
    • PMID:23108383
    • Van Damme M, Crompot E, Meuleman N, Mineur P, Bron D, Lagneaux L, Stamatopoulos B. HDAC isoenzyme expression is deregulated in chronic lymphocytic leukemia B-cells and has a complex prognostic significance. Epigenetics 2012; 7:1403-12; PMID:23108383; http://dx.doi.org/10.4161/ epi.22674
    • (2012) Epigenetics , vol.7 , pp. 1403-1412
    • Van Damme, M.1    Crompot, E.2    Meuleman, N.3    Mineur, P.4    Bron, D.5    Lagneaux, L.6    Stamatopoulos, B.7
  • 24
    • 78650742637 scopus 로고    scopus 로고
    • The role of HDAC6 in cancer
    • PMID:21076528
    • Aldana-Masangkay GI, Sakamoto KM. The role of HDAC6 in cancer. J Biomed Biotechnol 2011; 2011:875824; PMID:21076528; http://dx.doi.org/ 10.1155/2011/875824
    • (2011) J Biomed Biotechnol , vol.2011
    • Aldana-Masangkay, G.I.1    Sakamoto, K.M.2
  • 25
    • 84875252514 scopus 로고    scopus 로고
    • HDAC6 promotes hepatocellular carcinoma progression by inhibiting P53 transcriptional activity
    • PMID:23402884
    • Ding G, Liu HD, Huang Q, Liang HX, Ding ZH, Liao ZJ, Huang G. HDAC6 promotes hepatocellular carcinoma progression by inhibiting P53 transcriptional activity. FEBS Lett 2013; 587:880-6; PMID:23402884; http://dx.doi.org/10.1016/j.febslet. 2013.02.001
    • (2013) FEBS Lett , vol.587 , pp. 880-886
    • Ding, G.1    Liu, H.D.2    Huang, Q.3    Liang, H.X.4    Ding, Z.H.5    Liao, Z.J.6    Huang, G.7
  • 26
    • 22744446856 scopus 로고    scopus 로고
    • Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer
    • PMID:15806142
    • Saji S, Kawakami M, Hayashi S, Yoshida N, Hirose M, Horiguchi S, Itoh A, Funata N, Schreiber SL, Yoshida M, et al. Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer. Oncogene 2005; 24:4531-9; PMID:15806142; http://dx.doi.org/ 10.1038/sj.onc.1208646
    • (2005) Oncogene , vol.24 , pp. 4531-4539
    • Saji, S.1    Kawakami, M.2    Hayashi, S.3    Yoshida, N.4    Hirose, M.5    Horiguchi, S.6    Itoh, A.7    Funata, N.8    Schreiber, S.L.9    Yoshida, M.10
  • 28
    • 4544322261 scopus 로고    scopus 로고
    • Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients
    • PMID:15305372
    • Osada H, Tatematsu Y, Saito H, Yatabe Y, Mitsudomi T, Takahashi T. Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients. Int J Cancer 2004; 112:26-32; PMID:15305372; http://dx.doi.org/10.1002/ijc.20395
    • (2004) Int J Cancer , vol.112 , pp. 26-32
    • Osada, H.1    Tatematsu, Y.2    Saito, H.3    Yatabe, Y.4    Mitsudomi, T.5    Takahashi, T.6
  • 29
    • 20844435806 scopus 로고    scopus 로고
    • Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma
    • PMID:15937109
    • Hideshima T, Bradner JE, Wong J, Chauhan D, Richardson P, Schreiber SL, Anderson KC. Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma. Proc Natl Acad Sci 2005; 102:8567-72; PMID:15937109
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 8567-8572
    • Hideshima, T.1    Bradner, J.E.2    Wong, J.3    Chauhan, D.4    Richardson, P.5    Schreiber, S.L.6    Anderson, K.C.7
  • 30
    • 81055149914 scopus 로고    scopus 로고
    • Mechanism of action of proteasome inhibitors and deacetylase inhibitors and the biological basis of synergy in multiple myeloma
    • PMID:22072815
    • Hideshima T, Richardson PG, Anderson KC. Mechanism of action of proteasome inhibitors and deacetylase inhibitors and the biological basis of synergy in multiple myeloma. Mol Cancer Ther 2011; 10:2034-42; PMID:22072815; http://dx.doi.org/10.1158/1535- 7163.MCT-11-0433
    • (2011) Mol Cancer Ther , vol.10 , pp. 2034-2042
    • Hideshima, T.1    Richardson, P.G.2    Anderson, K.C.3
  • 31
    • 84858640254 scopus 로고    scopus 로고
    • Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma
    • PMID:22262760
    • Santo L, Hideshima T, Kung AL, Tseng JC, Tamang D, Yang M, Jarpe M, van Duzer JH, Mazitschek R, Ogier WC, et al. Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma. Blood 2012; 119:2579-89; PMID:22262760; http://dx.doi.org/ 10.1182/blood-2011-10-387365
    • (2012) Blood , vol.119 , pp. 2579-2589
    • Santo, L.1    Hideshima, T.2    Kung, A.L.3    Tseng, J.C.4    Tamang, D.5    Yang, M.6    Jarpe, M.7    van Duzer, J.H.8    Mazitschek, R.9    Ogier, W.C.10
  • 32
    • 84880696667 scopus 로고    scopus 로고
    • Histone deacetylase (HDAC) inhibitors as single agents induce multiple myeloma cell death principally through the inhibition of class I HDAC
    • PMID:23692150
    • Mithraprabhu S, Khong T, Jones SS, Spencer A. Histone deacetylase (HDAC) inhibitors as single agents induce multiple myeloma cell death principally through the inhibition of class I HDAC. Br J Haematol 2013; PMID:23692150; http://dx.doi.org/10.1111/ bjh.12388
    • (2013) Br J Haematol
    • Mithraprabhu, S.1    Khong, T.2    Jones, S.S.3    Spencer, A.4
  • 33
    • 77955871803 scopus 로고    scopus 로고
    • Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma
    • PMID:20351311
    • Kikuchi J, Wada T, Shimizu R, Izumi T, Akutsu M, Mitsunaga K, Noborio-Hatano K, Nobuyoshi M, Ozawa K, Kano Y, et al. Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma. Blood 2010; 116:406-17; PMID:20351311; http://dx.doi.org/10.1182/blood- 2009-07-235663
    • (2010) Blood , vol.116 , pp. 406-417
    • Kikuchi, J.1    Wada, T.2    Shimizu, R.3    Izumi, T.4    Akutsu, M.5    Mitsunaga, K.6    Noborio-Hatano, K.7    Nobuyoshi, M.8    Ozawa, K.9    Kano, Y.10
  • 34
    • 0022517180 scopus 로고
    • Establishment and characterization of a human plasma cell myeloma culture having a rearranged cellular myc proto-oncogene
    • PMID:2423157
    • Gazdar AF, Oie HK, Kirsch IR, Hollis GF. Establishment and characterization of a human plasma cell myeloma culture having a rearranged cellular myc proto-oncogene. Blood 1986; 67:1542-9; PMID:2423157
    • (1986) Blood , vol.67 , pp. 1542-1549
    • Gazdar, A.F.1    Oie, H.K.2    Kirsch, I.R.3    Hollis, G.F.4
  • 35
    • 0026005560 scopus 로고
    • Role of interleukin-6 in the proliferation of human multiple myeloma cell lines OCI-My 1 to 7 established from patients with advanced stage of the disease
    • PMID:1912582
    • Hitzler JK, Martinez-Valdez H, Bergsagel DB, Minden MD, Messner HA. Role of interleukin-6 in the proliferation of human multiple myeloma cell lines OCI-My 1 to 7 established from patients with advanced stage of the disease. Blood 1991; 78:1996-2004; PMID:1912582
    • (1991) Blood , vol.78 , pp. 1996-2004
    • Hitzler, J.K.1    Martinez-Valdez, H.2    Bergsagel, D.B.3    Minden, M.D.4    Messner, H.A.5
  • 36
    • 0027420353 scopus 로고
    • Coexistence of aneuploid subclones within a myeloma cell line that exhibits clonal immunoglobulin gene rearrangement: Clinical implications
    • PMID:8221668
    • Jelinek DF, Ahmann GJ, Greipp PR, Jalal SM, Westendorf JJ, Katzmann JA, Kyle RA, Lust JA. Coexistence of aneuploid subclones within a myeloma cell line that exhibits clonal immunoglobulin gene rearrangement: clinical implications. Cancer Res 1993; 53:5320-7; PMID:8221668
    • (1993) Cancer Res , vol.53 , pp. 5320-5327
    • Jelinek, D.F.1    Ahmann, G.J.2    Greipp, P.R.3    Jalal, S.M.4    Westendorf, J.J.5    Katzmann, J.A.6    Kyle, R.A.7    Lust, J.A.8
  • 37
    • 0033027596 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization analysis shows the frequent occurrence of 14q32.3 rearrangements with involvement of immunoglobulin switch regions in myeloma cell lines
    • PMID:10087940
    • Kuipers J, Vaandrager JW, Weghuis DO, Pearson PL, Scheres J, Lokhorst HM, Clevers H, Bast BJ. Fluorescence in situ hybridization analysis shows the frequent occurrence of 14q32.3 rearrangements with involvement of immunoglobulin switch regions in myeloma cell lines. Cancer Genet Cytogenet 1999; 109:99-107; PMID:10087940; http://dx.doi.org/10.1016/S0165- 4608(98)00157-5
    • (1999) Cancer Genet Cytogenet , vol.109 , pp. 99-107
    • Kuipers, J.1    Vaandrager, J.W.2    Weghuis, D.O.3    Pearson, P.L.4    Scheres, J.5    Lokhorst, H.M.6    Clevers, H.7    Bast, B.J.8
  • 39
    • 52149094341 scopus 로고    scopus 로고
    • Characterization of MYC translocations in multiple myeloma cell lines
    • PMID:18647998
    • Dib A, Gabrea A, Glebov OK, Bergsagel PL, Kuehl WM. Characterization of MYC translocations in multiple myeloma cell lines. J Natl Cancer Inst Monogr 2008:25-31; PMID:18647998; http://dx.doi.org/ 10.1093/jncimonographs/lgn011
    • (2008) J Natl Cancer Inst Monogr , pp. 25-31
    • Dib, A.1    Gabrea, A.2    Glebov, O.K.3    Bergsagel, P.L.4    Kuehl, W.M.5
  • 41
    • 71049179047 scopus 로고    scopus 로고
    • Expression levels of histone deacetylases determine the cell fate of hematopoietic progenitors
    • PMID:19736310
    • Wada T, Kikuchi J, Nishimura N, Shimizu R, Kitamura T, Furukawa Y. Expression levels of histone deacetylases determine the cell fate of hematopoietic progenitors. J Biol Chem 2009; 284:30673-83; PMID:19736310; http://dx.doi.org/10.1074/jbc. M109.042242
    • (2009) J Biol Chem , vol.284 , pp. 30673-30683
    • Wada, T.1    Kikuchi, J.2    Nishimura, N.3    Shimizu, R.4    Kitamura, T.5    Furukawa, Y.6
  • 42
    • 84869880178 scopus 로고    scopus 로고
    • Histone deacetylases and cancer
    • PMID:22963873
    • Barneda-Zahonero B, Parra M. Histone deacetylases and cancer. Mol Oncol 2012; 6:579-89; PMID:22963873; http://dx.doi.org/10.1016/j. molonc.2012.07.003
    • (2012) Mol Oncol , vol.6 , pp. 579-589
    • Barneda-Zahonero, B.1    Parra, M.2
  • 43
    • 79251544228 scopus 로고    scopus 로고
    • Regulating the regulators: The post-translational code of class I HDAC1 and HDAC2
    • PMID:21197454
    • Segre CV, Chiocca S. Regulating the regulators: the post-translational code of class I HDAC1 and HDAC2. J Biomed Biotechnol 2011; 2011:690848; PMID:21197454; http://dx.doi.org/10.1155/2011/ 690848
    • (2011) J Biomed Biotechnol , vol.2011
    • Segre, C.V.1    Chiocca, S.2
  • 44
    • 34547897023 scopus 로고    scopus 로고
    • Histone deacetylases and cancer
    • PMID:17694083
    • Glozak MA, Seto E. Histone deacetylases and cancer. Oncogene 2007; 26:5420-32; PMID:17694083; http://dx.doi.org/10.1038/sj.onc.1210610
    • (2007) Oncogene , vol.26 , pp. 5420-5432
    • Glozak, M.A.1    Seto, E.2
  • 45
    • 78651350825 scopus 로고    scopus 로고
    • The DAC system and associations with multiple myeloma
    • PMID:21120582
    • Ocio EM, San Miguel JF. The DAC system and associations with multiple myeloma. Invest New Drugs 2010; 28 Suppl 1:S28-35; PMID:21120582; http://dx. doi.org/10.1007/s10637-010-9589-x
    • (2010) Invest New Drugs , vol.28 , pp. S28-S35
    • Ocio, E.M.1    San Miguel, J.F.2
  • 46
    • 80052180405 scopus 로고    scopus 로고
    • Class IIa HDACs: From important roles in differentiation to possible implications in tumourigenesis
    • PMID:21435179
    • Clocchiatti A, Florean C, Brancolini C. Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis. J Cell Mol Med 2011; 15:1833-46; PMID:21435179; http://dx.doi. org/10.1111/j.1582-4934.2011.01321.x
    • (2011) J Cell Mol Med , vol.15 , pp. 1833-1846
    • Clocchiatti, A.1    Florean, C.2    Brancolini, C.3
  • 47
    • 0037417373 scopus 로고    scopus 로고
    • Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response
    • PMID:12668657
    • Kao GD, McKenna WG, Guenther MG, Muschel RJ, Lazar MA, Yen TJ. Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. J Cell Biol 2003; 160:1017-27; PMID:12668657; http://dx. doi.org/10.1083/jcb.200209065
    • (2003) J Cell Biol , vol.160 , pp. 1017-1027
    • Kao, G.D.1    McKenna, W.G.2    Guenther, M.G.3    Muschel, R.J.4    Lazar, M.A.5    Yen, T.J.6
  • 49
    • 58249096131 scopus 로고    scopus 로고
    • HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53- independent mechanism
    • PMID:18850004
    • Mottet D, Pirotte S, Lamour V, Hagedorn M, Javerzat S, Bikfalvi A, Bellahcene A, Verdin E, Castronovo V. HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53- independent mechanism. Oncogene 2009; 28:243-56; PMID:18850004; http://dx.doi.org/10.1038/ onc.2008.371
    • (2009) Oncogene , vol.28 , pp. 243-256
    • Mottet, D.1    Pirotte, S.2    Lamour, V.3    Hagedorn, M.4    Javerzat, S.5    Bikfalvi, A.6    Bellahcene, A.7    Verdin, E.8    Castronovo, V.9
  • 50
    • 84879574177 scopus 로고    scopus 로고
    • The functional interactome landscape of the human histone deacetylase family
    • PMID:23752268
    • Joshi P, Greco TM, Guise AJ, Luo Y, Yu F, Nesvizhskii AI, Cristea IM. The functional interactome landscape of the human histone deacetylase family. Mol Syst Biol 2013; 9:672; PMID:23752268; http://dx.doi.org/ 10.1038/msb.2013.26
    • (2013) Mol Syst Biol , vol.9 , pp. 672
    • Joshi, P.1    Greco, T.M.2    Guise, A.J.3    Luo, Y.4    Yu, F.5    Nesvizhskii, A.I.6    Cristea, I.M.7
  • 53
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • PMID:11328886
    • Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001; 29:e45; PMID:11328886; http://dx.doi.org/ 10.1093/nar/29.9.e45
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.