-
1
-
-
84896690513
-
Prevalence of childhood and adult obesity in the United States, 2011–2012
-
4570244
-
Ogden CL, Carroll MD, Kit BK, Flegal KM, Prevalence of childhood and adult obesity in the United States, 2011–2012. JAMA. 2014;311(8):806–14. doi: 10.1001/jama.2014.73224570244
-
(2014)
JAMA
, vol.311
, Issue.8
, pp. 806-814
-
-
Ogden, C.L.1
Carroll, M.D.2
Kit, B.K.3
Flegal, K.M.4
-
2
-
-
84884148585
-
The impact of obesity on US mortality levels: the importance of age and cohort factors in population estimates
-
3948004
-
Masters RK, Reither EN, Powers DA, Yang YC, Burger AE, Link BG, The impact of obesity on US mortality levels: the importance of age and cohort factors in population estimates. Am J Public Health. 2013;103(10):1895–901. doi: 10.2105/AJPH.2013.30137923948004
-
(2013)
Am J Public Health
, vol.103
, Issue.10
, pp. 1895-1901
-
-
Masters, R.K.1
Reither, E.N.2
Powers, D.A.3
Yang, Y.C.4
Burger, A.E.5
Link, B.G.6
-
3
-
-
84896134029
-
Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1.8 million participants
-
4269108
-
Lu Y, Hajifathalian K, Ezzati M, Woodward M, Rimm EB, Danaei G, Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1.8 million participants. Lancet. 2014;383(9921):970–83. doi: 10.1016/S0140-6736(13)61836-X24269108
-
(2014)
Lancet
, vol.383
, Issue.9921
, pp. 970-983
-
-
Lu, Y.1
Hajifathalian, K.2
Ezzati, M.3
Woodward, M.4
Rimm, E.B.5
Danaei, G.6
-
4
-
-
84878594902
-
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
-
3563607
-
Berndt SI, Gustafsson S, Magi R, Ganna A, Wheeler E, Feitosa MF, et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet. 2013;45(5):501–12. doi: 10.1038/ng.260623563607
-
(2013)
Nat Genet
, vol.45
, Issue.5
, pp. 501-512
-
-
Berndt, S.I.1
Gustafsson, S.2
Magi, R.3
Ganna, A.4
Wheeler, E.5
Feitosa, M.F.6
-
5
-
-
78049337953
-
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
-
0935630
-
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet. 2010;42(11):937–48. doi: 10.1038/ng.68620935630
-
(2010)
Nat Genet
, vol.42
, Issue.11
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
Monda, K.L.4
Thorleifsson, G.5
Jackson, A.U.6
-
6
-
-
84897145037
-
Gene-lifestyle interactions in obesity
-
4392269,.;: –
-
van Vliet-Ostaptchouk JV, Snieder H, Lagou V, Gene-lifestyle interactions in obesity. Curr Nutr Rep. 2012;1:184–96. doi: 10.1007/s13668-012-0022-224392269
-
(2012)
Curr Nutr Rep
, vol.1
, pp. 184-196
-
-
van Vliet-Ostaptchouk, J.V.1
Snieder, H.2
Lagou, V.3
-
7
-
-
84923171580
-
Genetic studies of body mass index yield new insights for obesity biology
-
5673413
-
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518(7538):197–206. doi: 10.1038/nature1417725673413
-
(2015)
Nature
, vol.518
, Issue.7538
, pp. 197-206
-
-
Locke, A.E.1
Kahali, B.2
Berndt, S.I.3
Justice, A.E.4
Pers, T.H.5
Day, F.R.6
-
8
-
-
78149381194
-
Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment
-
1048988,.;():
-
Relton CL, Davey Smith G, Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment. PLoS Med. 2010;7(10):e1000356. doi: 10.1371/journal.pmed.100035621048988
-
(2010)
PLoS Med
, vol.7
, Issue.10
, pp. e1000356
-
-
Relton, C.L.1
Davey Smith, G.2
-
9
-
-
84920672944
-
Epigenetics and human obesity
-
4566855
-
van Dijk SJ, Molloy PL, Varinli H, Morrison JL, Muhlhausler BS, Epigenetics and human obesity. Int J Obes (Lond). 2014;39(1):85–97. doi: 10.1038/ijo.2014.3424566855
-
(2014)
Int J Obes (Lond)
, vol.39
, Issue.1
, pp. 85-97
-
-
van Dijk, S.J.1
Molloy, P.L.2
Varinli, H.3
Morrison, J.L.4
Muhlhausler, B.S.5
-
10
-
-
84951123372
-
NIH working group report-using genomic information to guide weight management: From universal to precision treatment
-
6692578
-
Bray MS, Loos RJ, McCaffery JM, Ling C, Franks PW, Weinstock GM, et al. NIH working group report-using genomic information to guide weight management: From universal to precision treatment. Obesity (Silver Spring). 2016;24(1):14–22. doi: 10.1002/oby.2138126692578
-
(2016)
Obesity (Silver Spring)
, vol.24
, Issue.1
, pp. 14-22
-
-
Bray, M.S.1
Loos, R.J.2
McCaffery, J.M.3
Ling, C.4
Franks, P.W.5
Weinstock, G.M.6
-
11
-
-
84950268824
-
Mendelian randomization: applications and limitations in epigenetic studies
-
6639554
-
Relton CL, Davey Smith G, Mendelian randomization: applications and limitations in epigenetic studies. Epigenomics. 2015;7(8):1239–43. doi: 10.2217/epi.15.8826639554
-
(2015)
Epigenomics
, vol.7
, Issue.8
, pp. 1239-1243
-
-
Relton, C.L.1
Davey Smith, G.2
-
12
-
-
84858648623
-
Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease
-
2422451
-
Relton CL, Davey Smith G, Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease. Int J Epidemiol. 2012;41(1):161–76. doi: 10.1093/ije/dyr23322422451
-
(2012)
Int J Epidemiol
, vol.41
, Issue.1
, pp. 161-176
-
-
Relton, C.L.1
Davey Smith, G.2
-
13
-
-
85031678782
-
A review of instrumental variable estimators for Mendelian randomization
-
ug, 26282889
-
Burgess S, Small DS, Thompson SG, A review of instrumental variable estimators for Mendelian randomization. Stat Methods Med Res. 2015Aug17. doi: 10.1177/096228021559757926282889
-
(2015)
Stat Methods Med Res
-
-
Burgess, S.1
Small, D.S.2
Thompson, S.G.3
-
14
-
-
0018612858
-
An investigation of coronary heart disease in families. The Framingham offspring study
-
74565
-
Kannel WB, Feinleib M, McNamara PM, Garrison RJ, Castelli WP, An investigation of coronary heart disease in families. The Framingham offspring study. Am J Epidemiol. 1979;110(3):281–90. 474565
-
(1979)
Am J Epidemiol
, vol.110
, Issue.3
, pp. 281-290
-
-
Kannel, W.B.1
Feinleib, M.2
McNamara, P.M.3
Garrison, R.J.4
Castelli, W.P.5
-
15
-
-
1642455817
-
The impact of childhood intelligence on later life: following up the Scottish mental surveys of 1932 and 1947
-
4717632
-
Deary IJ, Whiteman MC, Starr JM, Whalley LJ, Fox HC, The impact of childhood intelligence on later life: following up the Scottish mental surveys of 1932 and 1947. J Pers Soc Psychol. 2004;86(1):130–47. doi: 10.1037/0022-3514.86.1.13014717632
-
(2004)
J Pers Soc Psychol
, vol.86
, Issue.1
, pp. 130-147
-
-
Deary, I.J.1
Whiteman, M.C.2
Starr, J.M.3
Whalley, L.J.4
Fox, H.C.5
-
16
-
-
38849151645
-
The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age 11 to age 70 and beyond
-
8053258,..;:
-
Deary IJ, Gow AJ, Taylor MD, Corley J, Brett C, Wilson V, et al. The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age 11 to age 70 and beyond. BMC Geriatr. 2007;7:28. doi: 10.1186/1471-2318-7-2818053258
-
(2007)
BMC Geriatr
, vol.7
, pp. 28
-
-
Deary, I.J.1
Gow, A.J.2
Taylor, M.D.3
Corley, J.4
Brett, C.5
Wilson, V.6
-
17
-
-
84863447605
-
Cohort profile: the Lothian Birth Cohorts of 1921 and 1936
-
2253310
-
Deary IJ, Gow AJ, Pattie A, Starr JM, Cohort profile: the Lothian Birth Cohorts of 1921 and 1936. Int J Epidemiol. 2012;41(6):1576–84. doi: 10.1093/ije/dyr19722253310
-
(2012)
Int J Epidemiol
, vol.41
, Issue.6
, pp. 1576-1584
-
-
Deary, I.J.1
Gow, A.J.2
Pattie, A.3
Starr, J.M.4
-
18
-
-
0002572171
-
Epidemiological approaches to heart disease: the Framingham Study
-
4819398
-
Dawber TR, Meadors GF, Moore FE, JrEpidemiological approaches to heart disease: the Framingham Study. Am J Public Health Nations Health. 1951;41(3):279–81. 14819398
-
(1951)
Am J Public Health Nations Health
, vol.41
, Issue.3
, pp. 279-281
-
-
Dawber, T.R.1
Meadors, G.F.2
Moore, F.E.3
-
19
-
-
80053304450
-
High density DNA methylation array with single CpG site resolution
-
1839163
-
Bibikova M, Barnes B, Tsan C, Ho V, Klotzle B, Le JM, et al. High density DNA methylation array with single CpG site resolution. Genomics. 2011;98(4):288–95. doi: 10.1016/j.ygeno.2011.07.00721839163
-
(2011)
Genomics
, vol.98
, Issue.4
, pp. 288-295
-
-
Bibikova, M.1
Barnes, B.2
Tsan, C.3
Ho, V.4
Klotzle, B.5
Le, J.M.6
-
20
-
-
84892470422
-
Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes
-
4057673
-
Zhang X, Johnson AD, Hendricks AE, Hwang SJ, Tanriverdi K, Ganesh SK, et al. Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes. Hum Mol Genet. 2014;23(3):782–95. doi: 10.1093/hmg/ddt46124057673
-
(2014)
Hum Mol Genet
, vol.23
, Issue.3
, pp. 782-795
-
-
Zhang, X.1
Johnson, A.D.2
Hendricks, A.E.3
Hwang, S.J.4
Tanriverdi, K.5
Ganesh, S.K.6
-
21
-
-
84859098571
-
The sva package for removing batch effects and other unwanted variation in high-throughput experiments
-
2257669
-
Leek JT, Johnson WE, Parker HS, Jaffe AE, Storey JD, The sva package for removing batch effects and other unwanted variation in high-throughput experiments. Bioinformatics. 2012;28(6):882–3. doi: 10.1093/bioinformatics/bts03422257669
-
(2012)
Bioinformatics
, vol.28
, Issue.6
, pp. 882-883
-
-
Leek, J.T.1
Johnson, W.E.2
Parker, H.S.3
Jaffe, A.E.4
Storey, J.D.5
-
22
-
-
79960277368
-
Optimally weighted Z-test is a powerful method for combining probabilities in meta-analysis
-
1605215
-
Zaykin DV, Optimally weighted Z-test is a powerful method for combining probabilities in meta-analysis. J Evol Biol. 2011;24(8):1836–41. doi: 10.1111/j.1420-9101.2011.02297.x21605215
-
(2011)
J Evol Biol
, vol.24
, Issue.8
, pp. 1836-1841
-
-
Zaykin, D.V.1
-
23
-
-
84892511644
-
Large-scale gene function analysis with the PANTHER classification system
-
3868073
-
Mi H, Muruganujan A, Casagrande JT, Thomas PD, Large-scale gene function analysis with the PANTHER classification system. Nat Protoc. 2013;8(8):1551–66. doi: 10.1038/nprot.2013.09223868073
-
(2013)
Nat Protoc
, vol.8
, Issue.8
, pp. 1551-1566
-
-
Mi, H.1
Muruganujan, A.2
Casagrande, J.T.3
Thomas, P.D.4
-
24
-
-
85003856277
-
eFORGE: a tool for identifying cell type-specific signal in epigenomic data
-
7851974
-
Breeze CE, Paul DS, van Dongen J, Butcher LM, Ambrose JC, Barrett JE, et al. eFORGE: a tool for identifying cell type-specific signal in epigenomic data. Cell Rep. 2016;17(8):2137–50. doi: 10.1016/j.celrep.2016.10.05927851974
-
(2016)
Cell Rep
, vol.17
, Issue.8
, pp. 2137-2150
-
-
Breeze, C.E.1
Paul, D.S.2
van Dongen, J.3
Butcher, L.M.4
Ambrose, J.C.5
Barrett, J.E.6
-
25
-
-
84923362619
-
Integrative analysis of 111 reference human epigenomes
-
5693563
-
Roadmap Epigenomics ConsortiumKundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, et al. Integrative analysis of 111 reference human epigenomes. Nature. 2015;518(7539):317–30. doi: 10.1038/nature1424825693563
-
(2015)
Nature
, vol.518
, Issue.7539
, pp. 317-330
-
-
Kundaje, A.1
Meuleman, W.2
Ernst, J.3
Bilenky, M.4
Yen, A.5
-
26
-
-
84857980747
-
BLUEPRINT to decode the epigenetic signature written in blood
-
2398613
-
Adams D, Altucci L, Antonarakis SE, Ballesteros J, Beck S, Bird A, et al. BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol. 2012;30(3):224–6. doi: 10.1038/nbt.215322398613
-
(2012)
Nat Biotechnol
, vol.30
, Issue.3
, pp. 224-226
-
-
Adams, D.1
Altucci, L.2
Antonarakis, S.E.3
Ballesteros, J.4
Beck, S.5
Bird, A.6
-
27
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
2955616
-
ENCODE Project ConsortiumAn integrated encyclopedia of DNA elements in the human genome. Nature. 2012;489(7414):57–74. doi: 10.1038/nature1124722955616
-
(2012)
Nature
, vol.489
, Issue.7414
, pp. 57-74
-
-
-
28
-
-
84921316380
-
DNA methylation and body-mass index: a genome-wide analysis
-
4630777
-
Dick KJ, Nelson CP, Tsaprouni L, Sandling JK, Aissi D, Wahl S, et al. DNA methylation and body-mass index: a genome-wide analysis. Lancet. 2014;383(9933):1990–8. doi: 10.1016/S0140-6736(13)62674-424630777
-
(2014)
Lancet
, vol.383
, Issue.9933
, pp. 1990-1998
-
-
Dick, K.J.1
Nelson, C.P.2
Tsaprouni, L.3
Sandling, J.K.4
Aissi, D.5
Wahl, S.6
-
29
-
-
84932615545
-
Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference
-
6110892
-
Aslibekyan S, Demerath EW, Mendelson M, Zhi D, Guan W, Liang L, et al. Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference. Obesity (Silver Spring). 2015;23(7):1493–501. doi: 10.1002/oby.2111126110892
-
(2015)
Obesity (Silver Spring)
, vol.23
, Issue.7
, pp. 1493-1501
-
-
Aslibekyan, S.1
Demerath, E.W.2
Mendelson, M.3
Zhi, D.4
Guan, W.5
Liang, L.6
-
30
-
-
85018215032
-
Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci
-
5935004
-
Demerath EW, Guan W, Grove ML, Aslibekyan S, Mendelson M, Zhou YH, et al. Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci. Hum Mol Genet. 2015;24(15):4464–79. doi: 10.1093/hmg/ddv16125935004
-
(2015)
Hum Mol Genet
, vol.24
, Issue.15
, pp. 4464-4479
-
-
Demerath, E.W.1
Guan, W.2
Grove, M.L.3
Aslibekyan, S.4
Mendelson, M.5
Zhou, Y.H.6
-
31
-
-
84956912733
-
Alterations of a cellular cholesterol metabolism network are a molecular feature of obesity-related type 2 diabetes and cardiovascular disease
-
6153245
-
Ding J, Reynolds LM, Zeller T, Muller C, Lohman K, Nicklas BJ, et al. Alterations of a cellular cholesterol metabolism network are a molecular feature of obesity-related type 2 diabetes and cardiovascular disease. Diabetes. 2015;64(10):3464–74. doi: 10.2337/db14-131426153245
-
(2015)
Diabetes
, vol.64
, Issue.10
, pp. 3464-3474
-
-
Ding, J.1
Reynolds, L.M.2
Zeller, T.3
Muller, C.4
Lohman, K.5
Nicklas, B.J.6
-
32
-
-
84961999842
-
Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood
-
6646899
-
Huang RC, Garratt ES, Pan H, Wu Y, Davis EA, Barton SJ, et al. Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood. Epigenetics. 2015;10(11):995–1005. doi: 10.1080/15592294.2015.108041126646899
-
(2015)
Epigenetics
, vol.10
, Issue.11
, pp. 995-1005
-
-
Huang, R.C.1
Garratt, E.S.2
Pan, H.3
Wu, Y.4
Davis, E.A.5
Barton, S.J.6
-
33
-
-
84936777834
-
Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood
-
5861810
-
Ronn T, Volkov P, Gillberg L, Kokosar M, Perfilyev A, Jacobsen AL, et al. Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood. Hum Mol Genet. 2015;24(13):3792–813. doi: 10.1093/hmg/ddv12425861810
-
(2015)
Hum Mol Genet
, vol.24
, Issue.13
, pp. 3792-3813
-
-
Ronn, T.1
Volkov, P.2
Gillberg, L.3
Kokosar, M.4
Perfilyev, A.5
Jacobsen, A.L.6
-
34
-
-
84957837239
-
Epigenetic associations of type 2 diabetes and BMI in an Arab population
-
6823690,..;:
-
Al Muftah WA, Al-Shafai M, Zaghlool SB, Visconti A, Tsai PC, Kumar P, et al. Epigenetic associations of type 2 diabetes and BMI in an Arab population. Clin Epigenetics. 2016;8:13. doi: 10.1186/s13148-016-0177-626823690
-
(2016)
Clin Epigenetics
, vol.8
, pp. 13
-
-
Al Muftah, W.A.1
Al-Shafai, M.2
Zaghlool, S.B.3
Visconti, A.4
Tsai, P.C.5
Kumar, P.6
-
35
-
-
84937848055
-
Differential DNA methylation in relation to age and health risks of obesity
-
6213922
-
Mansego ML, Milagro FI, Zulet MA, Moreno-Aliaga MJ, Martinez JA, Differential DNA methylation in relation to age and health risks of obesity. Int J Mol Sci. 2015;16(8):16816–32. doi: 10.3390/ijms16081681626213922
-
(2015)
Int J Mol Sci
, vol.16
, Issue.8
, pp. 16816-16832
-
-
Mansego, M.L.1
Milagro, F.I.2
Zulet, M.A.3
Moreno-Aliaga, M.J.4
Martinez, J.A.5
-
36
-
-
84984868359
-
Methylation of SOCS3 is inversely associated with metabolic syndrome in an epigenome-wide association study of obesity
-
ug, 27564309
-
Ali O, Cerjak D, Kent JW, JrJames R, Blangero J, Carless MA, et al. Methylation of SOCS3 is inversely associated with metabolic syndrome in an epigenome-wide association study of obesity. Epigenetics. 2016Aug26. doi: 10.1080/15592294.2016.121628427564309
-
(2016)
Epigenetics
-
-
Ali, O.1
Cerjak, D.2
Kent, J.W.3
James, R.4
Blangero, J.5
Carless, M.A.6
-
37
-
-
33947383704
-
Ablation of the cholesterol transporter adenosine triphosphate-binding cassette transporter G1 reduces adipose cell size and protects against diet-induced obesity
-
7194745
-
Buchmann J, Meyer C, Neschen S, Augustin R, Schmolz K, Kluge R, et al. Ablation of the cholesterol transporter adenosine triphosphate-binding cassette transporter G1 reduces adipose cell size and protects against diet-induced obesity. Endocrinology. 2007;148(4):1561–73. doi: 10.1210/en.2006-124417194745
-
(2007)
Endocrinology
, vol.148
, Issue.4
, pp. 1561-1573
-
-
Buchmann, J.1
Meyer, C.2
Neschen, S.3
Augustin, R.4
Schmolz, K.5
Kluge, R.6
-
38
-
-
79959210305
-
A conditional knockout resource for the genome-wide study of mouse gene function
-
1677750
-
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, et al. A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011;474(7351):337–42. doi: 10.1038/nature1016321677750
-
(2011)
Nature
, vol.474
, Issue.7351
, pp. 337-342
-
-
Skarnes, W.C.1
Rosen, B.2
West, A.P.3
Koutsourakis, M.4
Bushell, W.5
Iyer, V.6
-
39
-
-
26244431937
-
Homozygous carnitine palmitoyltransferase 1a (liver isoform) deficiency is lethal in the mouse
-
6169268
-
Nyman LR, Cox KB, Hoppel CL, Kerner J, Barnoski BL, Hamm DA, et al. Homozygous carnitine palmitoyltransferase 1a (liver isoform) deficiency is lethal in the mouse. Mol Genet Metab. 2005;86(1–2):179–87. doi: 10.1016/j.ymgme.2005.07.02116169268
-
(2005)
Mol Genet Metab
, vol.86
, Issue.1-2
, pp. 179-187
-
-
Nyman, L.R.1
Cox, K.B.2
Hoppel, C.L.3
Kerner, J.4
Barnoski, B.L.5
Hamm, D.A.6
-
40
-
-
0347623324
-
Generation of viable cholesterol-free mice
-
4684813,..;():
-
Wechsler A, Brafman A, Shafir M, Heverin M, Gottlieb H, Damari G, et al. Generation of viable cholesterol-free mice. Science. 2003;302(5653):2087. doi: 10.1126/science.109077614684813
-
(2003)
Science
, vol.302
, Issue.5653
, pp. 2087
-
-
Wechsler, A.1
Brafman, A.2
Shafir, M.3
Heverin, M.4
Gottlieb, H.5
Damari, G.6
-
41
-
-
0029797604
-
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
-
833906
-
Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL, Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J Clin Invest. 1996;98(7):1575–84. doi: 10.1172/JCI1189518833906
-
(1996)
J Clin Invest
, vol.98
, Issue.7
, pp. 1575-1584
-
-
Shimano, H.1
Horton, J.D.2
Hammer, R.E.3
Shimomura, I.4
Brown, M.S.5
Goldstein, J.L.6
-
42
-
-
36749063888
-
A mouse model of conditional lipodystrophy
-
7921248
-
Kim S, Huang LW, Snow KJ, Ablamunits V, Hasham MG, Young TH, et al. A mouse model of conditional lipodystrophy. Proc Natl Acad Sci U S A. 2007;104(42):16627–32. doi: 10.1073/pnas.070779710417921248
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.42
, pp. 16627-16632
-
-
Kim, S.1
Huang, L.W.2
Snow, K.J.3
Ablamunits, V.4
Hasham, M.G.5
Young, T.H.6
-
43
-
-
0032532152
-
Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy
-
784493
-
Shimomura I, Hammer RE, Richardson JA, Ikemoto S, Bashmakov Y, Goldstein JL, et al. Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy. Genes Dev. 1998;12(20):3182–94. 9784493
-
(1998)
Genes Dev
, vol.12
, Issue.20
, pp. 3182-3194
-
-
Shimomura, I.1
Hammer, R.E.2
Richardson, J.A.3
Ikemoto, S.4
Bashmakov, Y.5
Goldstein, J.L.6
-
44
-
-
20444388685
-
Transgenic mice overexpressing SREBP-1a under the control of the PEPCK promoter exhibit insulin resistance, but not diabetes
-
5949711
-
Takahashi A, Shimano H, Nakagawa Y, Yamamoto T, Motomura K, Matsuzaka T, et al. Transgenic mice overexpressing SREBP-1a under the control of the PEPCK promoter exhibit insulin resistance, but not diabetes. Biochim Biophys Acta. 2005;1740(3):427–33. doi: 10.1016/j.bbadis.2004.11.00615949711
-
(2005)
Biochim Biophys Acta
, vol.1740
, Issue.3
, pp. 427-433
-
-
Takahashi, A.1
Shimano, H.2
Nakagawa, Y.3
Yamamoto, T.4
Motomura, K.5
Matsuzaka, T.6
-
45
-
-
80052322958
-
Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA
-
1829388,..;():
-
Fehrmann RS, Jansen RC, Veldink JH, Westra HJ, Arends D, Bonder MJ, et al. Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. PLoS Genet. 2011;7(8):e1002197. doi: 10.1371/journal.pgen.100219721829388
-
(2011)
PLoS Genet
, vol.7
, Issue.8
, pp. e1002197
-
-
Fehrmann, R.S.1
Jansen, R.C.2
Veldink, J.H.3
Westra, H.J.4
Arends, D.5
Bonder, M.J.6
-
46
-
-
45149108420
-
Mapping the genetic architecture of gene expression in human liver
-
8462017,..;():
-
Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, et al. Mapping the genetic architecture of gene expression in human liver. PLoS Biol. 2008;6(5):e107. doi: 10.1371/journal.pbio.006010718462017
-
(2008)
PLoS Biol
, vol.6
, Issue.5
, pp. e107
-
-
Schadt, E.E.1
Molony, C.2
Chudin, E.3
Hao, K.4
Yang, X.5
Lum, P.Y.6
-
47
-
-
79959916375
-
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort
-
1602305
-
Greenawalt DM, Dobrin R, Chudin E, Hatoum IJ, Suver C, Beaulaurier J, et al. A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort. Genome Res. 2011;21(7):1008–16. doi: 10.1101/gr.112821.11021602305
-
(2011)
Genome Res
, vol.21
, Issue.7
, pp. 1008-1016
-
-
Greenawalt, D.M.1
Dobrin, R.2
Chudin, E.3
Hatoum, I.J.4
Suver, C.5
Beaulaurier, J.6
-
48
-
-
84890172667
-
Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements
-
4183450
-
Grundberg E, Meduri E, Sandling JK, Hedman AK, Keildson S, Buil A, et al. Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements. Am J Hum Genet. 2013;93(5):876–90. doi: 10.1016/j.ajhg.2013.10.00424183450
-
(2013)
Am J Hum Genet
, vol.93
, Issue.5
, pp. 876-890
-
-
Grundberg, E.1
Meduri, E.2
Sandling, J.K.3
Hedman, A.K.4
Keildson, S.5
Buil, A.6
-
49
-
-
78049349396
-
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
-
0935629
-
Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, et al. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet. 2010;42(11):949–60. doi: 10.1038/ng.68520935629
-
(2010)
Nat Genet
, vol.42
, Issue.11
, pp. 949-960
-
-
Heid, I.M.1
Jackson, A.U.2
Randall, J.C.3
Winkler, T.W.4
Qi, L.5
Steinthorsdottir, V.6
-
50
-
-
84859238629
-
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
-
2479202,..;():
-
Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 2012;8(3):e1002607. doi: 10.1371/journal.pgen.100260722479202
-
(2012)
PLoS Genet
, vol.8
, Issue.3
, pp. e1002607
-
-
Dastani, Z.1
Hivert, M.F.2
Timpson, N.3
Perry, J.R.4
Yuan, X.5
Scott, R.A.6
-
51
-
-
84871987100
-
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
-
3202124
-
Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, et al. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet. 2013;45(1):76–82. doi: 10.1038/ng.247723202124
-
(2013)
Nat Genet
, vol.45
, Issue.1
, pp. 76-82
-
-
Horikoshi, M.1
Yaghootkar, H.2
Mook-Kanamori, D.O.3
Sovio, U.4
Taal, H.R.5
Hennig, B.J.6
-
52
-
-
84868337361
-
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
-
2885922
-
Morris AP, Voight BF, Teslovich TM, Ferreira T, Segre AV, Steinthorsdottir V, et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012;44(9):981–90. doi: 10.1038/ng.238322885922
-
(2012)
Nat Genet
, vol.44
, Issue.9
, pp. 981-990
-
-
Morris, A.P.1
Voight, B.F.2
Teslovich, T.M.3
Ferreira, T.4
Segre, A.V.5
Steinthorsdottir, V.6
-
53
-
-
84861614905
-
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
-
2581228
-
Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet. 2012;44(6):659–69. doi: 10.1038/ng.227422581228
-
(2012)
Nat Genet
, vol.44
, Issue.6
, pp. 659-669
-
-
Manning, A.K.1
Hivert, M.F.2
Scott, R.A.3
Grimsby, J.L.4
Bouatia-Naji, N.5
Chen, H.6
-
54
-
-
78649461131
-
Common variants at 10 genomic loci influence hemoglobin A(1)(C) levels via glycemic and nonglycemic pathways
-
0858683
-
Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, et al. Common variants at 10 genomic loci influence hemoglobin A(1)(C) levels via glycemic and nonglycemic pathways. Diabetes. 2010;59(12):3229–39. doi: 10.2337/db10-050220858683
-
(2010)
Diabetes
, vol.59
, Issue.12
, pp. 3229-3239
-
-
Soranzo, N.1
Sanna, S.2
Wheeler, E.3
Gieger, C.4
Radke, D.5
Dupuis, J.6
-
55
-
-
75749086085
-
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
-
0081858
-
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010;42(2):105–16. doi: 10.1038/ng.52020081858
-
(2010)
Nat Genet
, vol.42
, Issue.2
, pp. 105-116
-
-
Dupuis, J.1
Langenberg, C.2
Prokopenko, I.3
Saxena, R.4
Soranzo, N.5
Jackson, A.U.6
-
56
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
0686565
-
Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010;466(7307):707–13. doi: 10.1038/nature0927020686565
-
(2010)
Nature
, vol.466
, Issue.7307
, pp. 707-713
-
-
Teslovich, T.M.1
Musunuru, K.2
Smith, A.V.3
Edmondson, A.C.4
Stylianou, I.M.5
Koseki, M.6
-
57
-
-
84871969762
-
Large-scale association analysis identifies new risk loci for coronary artery disease
-
3202125
-
CARDIoGRAMplusC4D ConsortiumDeloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, et al. Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet. 2013;45(1):25–33. doi: 10.1038/ng.248023202125
-
(2013)
Nat Genet
, vol.45
, Issue.1
, pp. 25-33
-
-
Deloukas, P.1
Kanoni, S.2
Willenborg, C.3
Farrall, M.4
Assimes, T.L.5
-
58
-
-
77951533290
-
Genome-wide association of lipid-lowering response to statins in combined study populations
-
0339536,..;():
-
Barber MJ, Mangravite LM, Hyde CL, Chasman DI, Smith JD, McCarty CA, et al. Genome-wide association of lipid-lowering response to statins in combined study populations. PLoS ONE. 2010;5(3):e9763. doi: 10.1371/journal.pone.000976320339536
-
(2010)
PLoS ONE
, vol.5
, Issue.3
, pp. e9763
-
-
Barber, M.J.1
Mangravite, L.M.2
Hyde, C.L.3
Chasman, D.I.4
Smith, J.D.5
McCarty, C.A.6
-
59
-
-
69949176863
-
Common regulatory variation impacts gene expression in a cell type-dependent manner
-
9644074
-
Dimas AS, Deutsch S, Stranger BE, Montgomery SB, Borel C, Attar-Cohen H, et al. Common regulatory variation impacts gene expression in a cell type-dependent manner. Science. 2009;325(5945):1246–50. doi: 10.1126/science.117414819644074
-
(2009)
Science
, vol.325
, Issue.5945
, pp. 1246-1250
-
-
Dimas, A.S.1
Deutsch, S.2
Stranger, B.E.3
Montgomery, S.B.4
Borel, C.5
Attar-Cohen, H.6
-
60
-
-
84929001104
-
Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans
-
5954001
-
Consortium GTEx, Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. Science. 2015;348(6235):648–60. doi: 10.1126/science.126211025954001
-
(2015)
Science
, vol.348
, Issue.6235
, pp. 648-660
-
-
Consortium, G.T.E.1
-
61
-
-
84887099827
-
Discovery and refinement of loci associated with lipid levels
-
4097068
-
Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, et al. Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013;45(11):1274–83. doi: 10.1038/ng.279724097068
-
(2013)
Nat Genet
, vol.45
, Issue.11
, pp. 1274-1283
-
-
Willer, C.J.1
Schmidt, E.M.2
Sengupta, S.3
Peloso, G.M.4
Gustafsson, S.5
Kanoni, S.6
-
62
-
-
62849107573
-
Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies
-
9299006
-
Whitlock G, Lewington S, Sherliker P, Clarke R, Emberson J, Halsey J, et al. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet. 2009;373(9669):1083–96. doi: 10.1016/S0140-6736(09)60318-419299006
-
(2009)
Lancet
, vol.373
, Issue.9669
, pp. 1083-1096
-
-
Whitlock, G.1
Lewington, S.2
Sherliker, P.3
Clarke, R.4
Emberson, J.5
Halsey, J.6
-
63
-
-
84929947002
-
The sex-specific association between BMI and coronary heart disease: a systematic review and meta-analysis of 95 cohorts with 1.2 million participants
-
5960160
-
Mongraw-Chaffin ML, Peters SA, Huxley RR, Woodward M, The sex-specific association between BMI and coronary heart disease: a systematic review and meta-analysis of 95 cohorts with 1.2 million participants. Lancet Diabetes Endocrinol. 2015;3(6):437–49. doi: 10.1016/S2213-8587(15)00086-825960160
-
(2015)
Lancet Diabetes Endocrinol
, vol.3
, Issue.6
, pp. 437-449
-
-
Mongraw-Chaffin, M.L.1
Peters, S.A.2
Huxley, R.R.3
Woodward, M.4
-
64
-
-
77952863834
-
Genetic control of de novo lipogenesis: role in diet-induced obesity
-
0218765
-
Strable MS, Ntambi JM, Genetic control of de novo lipogenesis: role in diet-induced obesity. Crit Rev Biochem Mol Biol. 2010;45(3):199–214. doi: 10.3109/1040923100366750020218765
-
(2010)
Crit Rev Biochem Mol Biol
, vol.45
, Issue.3
, pp. 199-214
-
-
Strable, M.S.1
Ntambi, J.M.2
-
65
-
-
79953755370
-
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice
-
1459323
-
Li Y, Xu S, Mihaylova MM, Zheng B, Hou X, Jiang B, et al. AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice. Cell Metab. 2011;13(4):376–88. doi: 10.1016/j.cmet.2011.03.00921459323
-
(2011)
Cell Metab
, vol.13
, Issue.4
, pp. 376-388
-
-
Li, Y.1
Xu, S.2
Mihaylova, M.M.3
Zheng, B.4
Hou, X.5
Jiang, B.6
-
66
-
-
84887058576
-
Common variants associated with plasma triglycerides and risk for coronary artery disease
-
4097064
-
Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet. 2013;45(11):1345–52. doi: 10.1038/ng.279524097064
-
(2013)
Nat Genet
, vol.45
, Issue.11
, pp. 1345-1352
-
-
Do, R.1
Willer, C.J.2
Schmidt, E.M.3
Sengupta, S.4
Gao, C.5
Peloso, G.M.6
-
67
-
-
0030003635
-
Adrenalectomy reverses pre-existing obesity in adult genetically obese (ob/ob) mice
-
653144
-
Feldkircher KM, Mistry AM, Romsos DR, Adrenalectomy reverses pre-existing obesity in adult genetically obese (ob/ob) mice. Int J Obes Relat Metab Disord. 1996;20(3):232–5. 8653144
-
(1996)
Int J Obes Relat Metab Disord
, vol.20
, Issue.3
, pp. 232-235
-
-
Feldkircher, K.M.1
Mistry, A.M.2
Romsos, D.R.3
-
68
-
-
0015748455
-
The effect of adrenalectomy on the development of the obese-hyperglycemic syndrome in ob-ob mice
-
718888
-
Solomon J, Mayer J, The effect of adrenalectomy on the development of the obese-hyperglycemic syndrome in ob-ob mice. Endocrinology. 1973;93(2):510–2. doi: 10.1210/endo-93-2-5104718888
-
(1973)
Endocrinology
, vol.93
, Issue.2
, pp. 510-512
-
-
Solomon, J.1
Mayer, J.2
-
69
-
-
84922709227
-
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes
-
5662011
-
Perry RJ, Camporez JP, Kursawe R, Titchenell PM, Zhang D, Perry CJ, et al. Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes. Cell. 2015;160(4):745–58. doi: 10.1016/j.cell.2015.01.01225662011
-
(2015)
Cell
, vol.160
, Issue.4
, pp. 745-758
-
-
Perry, R.J.1
Camporez, J.P.2
Kursawe, R.3
Titchenell, P.M.4
Zhang, D.5
Perry, C.J.6
-
70
-
-
84928208608
-
Adipocyte Atp-binding cassette G1 promotes triglyceride storage, fat mass growth and human obesity
-
5249572
-
Frisdal E, Le Lay S, Hooton H, Poupel L, Olivier M, Alili R, et al. Adipocyte Atp-binding cassette G1 promotes triglyceride storage, fat mass growth and human obesity. Diabetes. 2015;64(3):840–55. doi: 10.2337/db14-024525249572
-
(2015)
Diabetes
, vol.64
, Issue.3
, pp. 840-855
-
-
Frisdal, E.1
Le Lay, S.2
Hooton, H.3
Poupel, L.4
Olivier, M.5
Alili, R.6
-
71
-
-
84893065053
-
Epigenome-wide association study of fasting measures of glucose, insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study
-
4170695
-
Hidalgo B, Irvin MR, Sha J, Zhi D, Aslibekyan S, Absher D, et al. Epigenome-wide association study of fasting measures of glucose, insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study. Diabetes. 2014;63(2):801–7. doi: 10.2337/db13-110024170695
-
(2014)
Diabetes
, vol.63
, Issue.2
, pp. 801-807
-
-
Hidalgo, B.1
Irvin, M.R.2
Sha, J.3
Zhi, D.4
Aslibekyan, S.5
Absher, D.6
-
72
-
-
84906050534
-
Epigenome-wide association study of fasting blood lipids in the Genetics of Lipid-lowering Drugs and Diet Network study
-
4920721
-
Irvin MR, Zhi D, Joehanes R, Mendelson M, Aslibekyan S, Claas SA, et al. Epigenome-wide association study of fasting blood lipids in the Genetics of Lipid-lowering Drugs and Diet Network study. Circulation. 2014;130(7):565–72. doi: 10.1161/CIRCULATIONAHA.114.00915824920721
-
(2014)
Circulation
, vol.130
, Issue.7
, pp. 565-572
-
-
Irvin, M.R.1
Zhi, D.2
Joehanes, R.3
Mendelson, M.4
Aslibekyan, S.5
Claas, S.A.6
-
73
-
-
84942908108
-
DNA methylation of lipid-related genes affects blood lipid levels
-
5583993
-
Pfeiffer L, Wahl S, Pilling LC, Reischl E, Sandling JK, Kunze S, et al. DNA methylation of lipid-related genes affects blood lipid levels. Circ Cardiovasc Genet. 2015;8(2):334–42. doi: 10.1161/CIRCGENETICS.114.00080425583993
-
(2015)
Circ Cardiovasc Genet
, vol.8
, Issue.2
, pp. 334-342
-
-
Pfeiffer, L.1
Wahl, S.2
Pilling, L.C.3
Reischl, E.4
Sandling, J.K.5
Kunze, S.6
-
74
-
-
84934435676
-
Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study
-
6095709
-
Chambers JC, Loh M, Lehne B, Drong A, Kriebel J, Motta V, et al. Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study. Lancet Diabetes Endocrinol. 2015;3(7):526–34. doi: 10.1016/S2213-8587(15)00127-826095709
-
(2015)
Lancet Diabetes Endocrinol
, vol.3
, Issue.7
, pp. 526-534
-
-
Chambers, J.C.1
Loh, M.2
Lehne, B.3
Drong, A.4
Kriebel, J.5
Motta, V.6
-
75
-
-
85010965742
-
Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study
-
ep, 27634649
-
Sayols-Baixeras S, Subirana I, Lluis-Ganella C, Civeira F, Roquer J, Do AN, et al. Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study. Hum Mol Genet. 2016Sep15. doi: 10.1093/hmg/ddw28527634649
-
(2016)
Hum Mol Genet
-
-
Sayols-Baixeras, S.1
Subirana, I.2
Lluis-Ganella, C.3
Civeira, F.4
Roquer, J.5
Do, A.N.6
-
76
-
-
84976327016
-
Blood lipids influence DNA methylation in circulating cells
-
7350042,..;():
-
Dekkers KF, van Iterson M, Slieker RC, Moed MH, Bonder MJ, van Galen M, et al. Blood lipids influence DNA methylation in circulating cells. Genome Biol. 2016;17(1):138. doi: 10.1186/s13059-016-1000-627350042
-
(2016)
Genome Biol
, vol.17
, Issue.1
, pp. 138
-
-
Dekkers, K.F.1
van Iterson, M.2
Slieker, R.C.3
Moed, M.H.4
Bonder, M.J.5
van Galen, M.6
-
77
-
-
33845571750
-
Role of malonyl-CoA in heart disease and the hypothalamic control of obesity
-
7126822
-
Folmes CD, Lopaschuk GD, Role of malonyl-CoA in heart disease and the hypothalamic control of obesity. Cardiovasc Res. 2007;73(2):278–87. doi: 10.1016/j.cardiores.2006.10.00817126822
-
(2007)
Cardiovasc Res
, vol.73
, Issue.2
, pp. 278-287
-
-
Folmes, C.D.1
Lopaschuk, G.D.2
-
78
-
-
77951126550
-
Regulatory enzymes of mitochondrial beta-oxidation as targets for treatment of the metabolic syndrome
-
9694967
-
Schreurs M, Kuipers F, van der Leij FR, Regulatory enzymes of mitochondrial beta-oxidation as targets for treatment of the metabolic syndrome. Obes Rev. 2010;11(5):380–8. doi: 10.1111/j.1467-789X.2009.00642.x19694967
-
(2010)
Obes Rev
, vol.11
, Issue.5
, pp. 380-388
-
-
Schreurs, M.1
Kuipers, F.2
van der Leij, F.R.3
-
79
-
-
84959505464
-
Gut microbiota-derived lipopolysaccharide uptake and trafficking to adipose tissue: implications for inflammation and obesity
-
6712364
-
Hersoug LG, Moller P, Loft S, Gut microbiota-derived lipopolysaccharide uptake and trafficking to adipose tissue: implications for inflammation and obesity. Obes Rev. 2016;17(4):297–312. doi: 10.1111/obr.1237026712364
-
(2016)
Obes Rev
, vol.17
, Issue.4
, pp. 297-312
-
-
Hersoug, L.G.1
Moller, P.2
Loft, S.3
-
80
-
-
79953127124
-
Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation
-
1156799
-
Bansal K, Balaji KN, Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation. J Biol Chem. 2011;286(7):5823–35. doi: 10.1074/jbc.M110.19239321156799
-
(2011)
J Biol Chem
, vol.286
, Issue.7
, pp. 5823-5835
-
-
Bansal, K.1
Balaji, K.N.2
-
81
-
-
84891356760
-
Pivotal role of NOD2 in inflammatory processes affecting atherosclerosis and periodontal bone loss
-
4324141
-
Yuan H, Zelkha S, Burkatovskaya M, Gupte R, Leeman SE, Amar S, Pivotal role of NOD2 in inflammatory processes affecting atherosclerosis and periodontal bone loss. Proc Natl Acad Sci U S A. 2013;110(52):E5059–68. doi: 10.1073/pnas.132086211024324141
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.52
, pp. E5059-E5068
-
-
Yuan, H.1
Zelkha, S.2
Burkatovskaya, M.3
Gupte, R.4
Leeman, S.E.5
Amar, S.6
-
82
-
-
84945485028
-
A novel noninvasive diagnostic method for nonalcoholic steatohepatitis using two glycobiomarkers
-
6199205
-
Kamada Y, Ono M, Hyogo H, Fujii H, Sumida Y, Mori K, et al. A novel noninvasive diagnostic method for nonalcoholic steatohepatitis using two glycobiomarkers. Hepatology. 2015;62(5):1433–43. doi: 10.1002/hep.2800226199205
-
(2015)
Hepatology
, vol.62
, Issue.5
, pp. 1433-1443
-
-
Kamada, Y.1
Ono, M.2
Hyogo, H.3
Fujii, H.4
Sumida, Y.5
Mori, K.6
-
83
-
-
84970003875
-
Serum Mac-2 binding protein is a novel biomarker for chronic pancreatitis
-
7158210
-
Maekawa T, Kamada Y, Ebisutani Y, Ueda M, Hata T, Kawamoto K, et al. Serum Mac-2 binding protein is a novel biomarker for chronic pancreatitis. World J Gastroenterol. 2016;22(17):4403–10. doi: 10.3748/wjg.v22.i17.440327158210
-
(2016)
World J Gastroenterol
, vol.22
, Issue.17
, pp. 4403-4410
-
-
Maekawa, T.1
Kamada, Y.2
Ebisutani, Y.3
Ueda, M.4
Hata, T.5
Kawamoto, K.6
-
84
-
-
67651152853
-
Individuality and epigenetics in obesity
-
9413700
-
Campion J, Milagro FI, Martinez JA, Individuality and epigenetics in obesity. Obes Rev. 2009;10(4):383–92. doi: 10.1111/j.1467-789X.2009.00595.x19413700
-
(2009)
Obes Rev
, vol.10
, Issue.4
, pp. 383-392
-
-
Campion, J.1
Milagro, F.I.2
Martinez, J.A.3
-
85
-
-
84964678985
-
DNA methylation and body mass index: investigating identified methylation sites at HIF3A in a causal framework
-
6861784
-
Richmond RC, Sharp GC, Ward ME, Fraser A, Lyttleton O, McArdle WL, et al. DNA methylation and body mass index: investigating identified methylation sites at HIF3A in a causal framework. Diabetes. 2016;65(5):1231–44. doi: 10.2337/db15-099626861784
-
(2016)
Diabetes
, vol.65
, Issue.5
, pp. 1231-1244
-
-
Richmond, R.C.1
Sharp, G.C.2
Ward, M.E.3
Fraser, A.4
Lyttleton, O.5
McArdle, W.L.6
-
86
-
-
84897372328
-
Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits
-
4014485
-
Petersen AK, Zeilinger S, Kastenmuller G, Romisch-Margl W, Brugger M, Peters A, et al. Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits. Hum Mol Genet. 2014;23(2):534–45. doi: 10.1093/hmg/ddt43024014485
-
(2014)
Hum Mol Genet
, vol.23
, Issue.2
, pp. 534-545
-
-
Petersen, A.K.1
Zeilinger, S.2
Kastenmuller, G.3
Romisch-Margl, W.4
Brugger, M.5
Peters, A.6
-
87
-
-
80555124939
-
Ceramides as modulators of cellular and whole-body metabolism
-
2045572
-
Bikman BT, Summers SA, Ceramides as modulators of cellular and whole-body metabolism. J Clin Invest. 2011;121(11):4222–30. doi: 10.1172/JCI5714422045572
-
(2011)
J Clin Invest
, vol.121
, Issue.11
, pp. 4222-4230
-
-
Bikman, B.T.1
Summers, S.A.2
-
88
-
-
84935883118
-
Sphingolipids in cardiovascular diseases and metabolic disorders
-
6076974,.;:
-
Borodzicz S, Czarzasta K, Kuch M, Cudnoch-Jedrzejewska A, Sphingolipids in cardiovascular diseases and metabolic disorders. Lipids Health Dis. 2015;14:55. doi: 10.1186/s12944-015-0053-y26076974
-
(2015)
Lipids Health Dis
, vol.14
, pp. 55
-
-
Borodzicz, S.1
Czarzasta, K.2
Kuch, M.3
Cudnoch-Jedrzejewska, A.4
-
89
-
-
84937139245
-
Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes
-
5814122
-
Bellini L, Campana M, Mahfouz R, Carlier A, Veret J, Magnan C, et al. Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes. Expert Opin Ther Targets. 2015;19(8):1037–50. doi: 10.1517/14728222.2015.102835925814122
-
(2015)
Expert Opin Ther Targets
, vol.19
, Issue.8
, pp. 1037-1050
-
-
Bellini, L.1
Campana, M.2
Mahfouz, R.3
Carlier, A.4
Veret, J.5
Magnan, C.6
-
90
-
-
84897855294
-
Obesity-associated variants within FTO form long-range functional connections with IRX3
-
4646999
-
Smemo S, Tena JJ, Kim KH, Gamazon ER, Sakabe NJ, Gomez-Marin C, et al. Obesity-associated variants within FTO form long-range functional connections with IRX3. Nature. 2014;507(7492):371–5. doi: 10.1038/nature1313824646999
-
(2014)
Nature
, vol.507
, Issue.7492
, pp. 371-375
-
-
Smemo, S.1
Tena, J.J.2
Kim, K.H.3
Gamazon, E.R.4
Sakabe, N.J.5
Gomez-Marin, C.6
-
91
-
-
84937522502
-
Improving phenotypic prediction by combining genetic and epigenetic associations
-
6119815
-
Shah S, Bonder MJ, Marioni RE, Zhu Z, McRae AF, Zhernakova A, et al. Improving phenotypic prediction by combining genetic and epigenetic associations. Am J Hum Genet. 2015;97(1):75–85. doi: 10.1016/j.ajhg.2015.05.01426119815
-
(2015)
Am J Hum Genet
, vol.97
, Issue.1
, pp. 75-85
-
-
Shah, S.1
Bonder, M.J.2
Marioni, R.E.3
Zhu, Z.4
McRae, A.F.5
Zhernakova, A.6
-
92
-
-
84898935560
-
Predicting DNA methylation level across human tissues
-
4445802
-
Ma B, Wilker EH, Willis-Owen SA, Byun HM, Wong KC, Motta V, et al. Predicting DNA methylation level across human tissues. Nucleic Acids Res. 2014;42(6):3515–28. doi: 10.1093/nar/gkt138024445802
-
(2014)
Nucleic Acids Res
, vol.42
, Issue.6
, pp. 3515-3528
-
-
Ma, B.1
Wilker, E.H.2
Willis-Owen, S.A.3
Byun, H.M.4
Wong, K.C.5
Motta, V.6
|