Blood lipids influence DNA methylation in circulating cells

Genome Biology

Volumn 17, Issue 1, 2016, Pages

  Dekkers, Koen F ^a   van Iterson, Maarten ^a   Slieker, Roderick C ^a   Moed, Matthijs H ^a   Bonder, Marc Jan ^b   van Galen, Michiel ^a   Mei, Hailiang ^a   Zhernakova, Daria V ^b   van den Berg, Leonard H ^c   Deelen, Joris ^a   van Dongen, Jenny ^d   van Heemst, Diana ^a   Hofman, Albert ^e   Hottenga, Jouke J ^d   van der Kallen, Carla J H ^f   Schalkwijk, Casper G ^f   Stehouwer, Coen D A ^f   Tigchelaar, Ettje F ^b   Uitterlinden, André G ^e   Willemsen, Gonneke ^d   Zhernakova, Alexandra ^b   Franke, Lude ^b   't Hoen, Peter A C ^a   Jansen, Rick ^g   van Meurs, Joyce ^e   Boomsma, Dorret I ^d   van Duijn, Cornelia M ^e   van Greevenbroek, Marleen M J ^f   Veldink, Jan H ^c   Wijmenga, Cisca ^b   van Zwet, Erik W ^a   Slagboom, P Eline ^a   Jukema, J Wouter ^a   Heijmans, Bastiaan T ^a   more..

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d VU UNIVERSITY AMSTERDAM   (Netherlands)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^g VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^h BIOS Consortium   (Netherlands)

Author keywords

DNA methylation; Gene expression; Lipids; Mendelian randomization

Indexed keywords

ABC TRANSPORTER G1; DNA; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; RNA; TRIACYLGLYCEROL; CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE 1A, HUMAN; DHCR24 PROTEIN, HUMAN; LIPID; NERVE PROTEIN; OXIDOREDUCTASE; SREBF1 PROTEIN, HUMAN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ABCG1 GENE; ADULT; AGED; ARTICLE; CHOLESTEROL BLOOD LEVEL; CIRCULATING IMMUNE CELL; COHORT ANALYSIS; CONTROLLED STUDY; CPG ISLAND; CPT1A GENE; DHCR24 GENE; DNA METHYLATION; EPIGENETICS; FEEDBACK SYSTEM; FEMALE; GENE EXPRESSION; GENOMICS; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; LIPID METABOLISM; MALE; RNA SEQUENCE; SREBF1 GENE; TRIACYLGLYCEROL BLOOD LEVEL; ADOLESCENT; BLOOD; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HUMAN GENOME; MIDDLE AGED; VERY ELDERLY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY G, MEMBER 1; CARNITINE O-PALMITOYLTRANSFERASE; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION; GENOME, HUMAN; HUMANS; LIPID METABOLISM; LIPIDS; MALE; MIDDLE AGED; NERVE TISSUE PROTEINS; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIGLYCERIDES;

EID: 84976327016     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-016-1000-6     Document Type: Article

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