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Volumn 148, Issue 4, 2007, Pages 1561-1573

Ablation of the cholesterol transporter adenosine triphosphate-binding cassette transporter G1 reduces adipose cell size and protects against diet-induced obesity

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ATP BINDING CASSETTE TRANSPORTER G1; CHOLESTEROL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 33947383704     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-1244     Document Type: Article
Times cited : (70)

References (48)
  • 2
    • 4444340342 scopus 로고    scopus 로고
    • Target discovery in metabolic disease
    • Dohrmann CE 2004 Target discovery in metabolic disease. Drug Discov Today 9:785-794
    • (2004) Drug Discov Today , vol.9 , pp. 785-794
    • Dohrmann, C.E.1
  • 3
    • 0033863051 scopus 로고    scopus 로고
    • Type 2 diabetes-like hyperglycemia in a backcross model of NZO and SJL mice: Characterization of a susceptibility locus on chromosome 4 and its relation with obesity
    • Plum L, Kluge R, Giesen K, Altmuller J, Ortlepp JR, Joost HG 2000 Type 2 diabetes-like hyperglycemia in a backcross model of NZO and SJL mice: characterization of a susceptibility locus on chromosome 4 and its relation with obesity. Diabetes 49:1590-1596
    • (2000) Diabetes , vol.49 , pp. 1590-1596
    • Plum, L.1    Kluge, R.2    Giesen, K.3    Altmuller, J.4    Ortlepp, J.R.5    Joost, H.G.6
  • 4
    • 0034434695 scopus 로고    scopus 로고
    • Quantitative trait loci for obesity and insulin resistance (Nob1, Nob2) and their interaction with the leptin receptor allele (LeprA720T/T1044I) in New Zealand obese mice
    • Kluge R, Giesen K, Bahrenberg G, Plum L, Ortlepp JR, Joost HG 2000 Quantitative trait loci for obesity and insulin resistance (Nob1, Nob2) and their interaction with the leptin receptor allele (LeprA720T/T1044I) in New Zealand obese mice. Diabetologia 43:1565-1572
    • (2000) Diabetologia , vol.43 , pp. 1565-1572
    • Kluge, R.1    Giesen, K.2    Bahrenberg, G.3    Plum, L.4    Ortlepp, J.R.5    Joost, H.G.6
  • 5
    • 0036599146 scopus 로고    scopus 로고
    • Characterisation of the mouse diabetes susceptibilty locus Nidd/SJL: Islet cell destruction, interaction with the obesity QTL Nob1, and effect of dietary fat
    • Plum L, Giesen K, Kluge R, Junger E, Linnartz K, Schürmann A, Becker W, 2002 Characterisation of the mouse diabetes susceptibilty locus Nidd/SJL: islet cell destruction, interaction with the obesity QTL Nob1, and effect of dietary fat. Diabetologia 45:823-830
    • (2002) Diabetologia , vol.45 , pp. 823-830
    • Plum, L.1    Giesen, K.2    Kluge, R.3    Junger, E.4    Linnartz, K.5    Schürmann, A.6    Becker, W.7
  • 6
    • 0037449172 scopus 로고    scopus 로고
    • Diet-dependent obesity and hypercholesterolemia in the New Zealand obese mouse: Identification of a quantitative trait locus for elevated serum cholesterol on the distal mouse chromosome 5
    • Giesen K, Plum L, Kluge R, Ortlepp J, Joost HG 2003 Diet-dependent obesity and hypercholesterolemia in the New Zealand obese mouse: identification of a quantitative trait locus for elevated serum cholesterol on the distal mouse chromosome 5. Biochem Biophys Res Commun 304:812-817
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 812-817
    • Giesen, K.1    Plum, L.2    Kluge, R.3    Ortlepp, J.4    Joost, H.G.5
  • 7
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian ABC transporters in health and disease
    • Borst P, Elferink RO 2002 Mammalian ABC transporters in health and disease. Annu Rev Biochem 71:537-592
    • (2002) Annu Rev Biochem , vol.71 , pp. 537-592
    • Borst, P.1    Elferink, R.O.2
  • 10
    • 0034490992 scopus 로고    scopus 로고
    • Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency
    • Christiansen-Weber TA, Voland JR, Wu Y, Ngo K, Roland BL, Nguyen S, Peterson PA, Fung-Leung WP 2000 Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency. Am J Pathol 157:1017-1029
    • (2000) Am J Pathol , vol.157 , pp. 1017-1029
    • Christiansen-Weber, T.A.1    Voland, J.R.2    Wu, Y.3    Ngo, K.4    Roland, B.L.5    Nguyen, S.6    Peterson, P.A.7    Fung-Leung, W.P.8
  • 14
    • 0141835080 scopus 로고    scopus 로고
    • Clinical significance of high-density lipoproteins and the development of atherosclerosis: Focus on the role of the adenosine triphosphate-binding cassette protein A1 transporter
    • Brewer Jr HB, Santamarina-Fojo S 2003 Clinical significance of high-density lipoproteins and the development of atherosclerosis: focus on the role of the adenosine triphosphate-binding cassette protein A1 transporter. Am J Cardiol 92:10K-16K
    • (2003) Am J Cardiol , vol.92
    • Brewer Jr, H.B.1    Santamarina-Fojo, S.2
  • 15
    • 0036012793 scopus 로고    scopus 로고
    • Nuclear hormone receptors and cholesterol trafficking: The orphans find a new home
    • Fitzgerald ML, Moore KJ, Freeman MW 2002 Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home. J Mol Med 80:271-281
    • (2002) J Mol Med , vol.80 , pp. 271-281
    • Fitzgerald, M.L.1    Moore, K.J.2    Freeman, M.W.3
  • 16
    • 0037503924 scopus 로고    scopus 로고
    • Liver X receptor signaling pathways in cardiovascular disease
    • Tontonoz P, Mangelsdorf DJ 2003 Liver X receptor signaling pathways in cardiovascular disease. Mol Endocrinol 17:985-993
    • (2003) Mol Endocrinol , vol.17 , pp. 985-993
    • Tontonoz, P.1    Mangelsdorf, D.J.2
  • 17
    • 0345461478 scopus 로고    scopus 로고
    • Putative metabolic effects of the liver X receptor (LXR)
    • Steffensen KR, Gustafsson JA 2004 Putative metabolic effects of the liver X receptor (LXR). Diabetes 53(Suppl 1):S36-S42
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Steffensen, K.R.1    Gustafsson, J.A.2
  • 18
    • 0030239673 scopus 로고    scopus 로고
    • Molecular cloning of a mammalian ABC transporter homologous to Drosophila white gene
    • Savary S, Denizot F, Luciani M, Mattei M, Chimini G 1996 Molecular cloning of a mammalian ABC transporter homologous to Drosophila white gene. Mamm Genome 7:673-676
    • (1996) Mamm Genome , vol.7 , pp. 673-676
    • Savary, S.1    Denizot, F.2    Luciani, M.3    Mattei, M.4    Chimini, G.5
  • 21
    • 24044483233 scopus 로고    scopus 로고
    • ABCG1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins
    • Vaughan AM, Oram JF 2005 ABCG1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins. J Biol Chem 280:30150-30157
    • (2005) J Biol Chem , vol.280 , pp. 30150-30157
    • Vaughan, A.M.1    Oram, J.F.2
  • 26
    • 0018885161 scopus 로고
    • Skeletal muscle triacylglycerol in the rat: Methods for sampling and measurement, and studies of biological variability
    • Frayn KN, Maycock PF 1980 Skeletal muscle triacylglycerol in the rat: methods for sampling and measurement, and studies of biological variability. J Lipid Res 21:139-144
    • (1980) J Lipid Res , vol.21 , pp. 139-144
    • Frayn, K.N.1    Maycock, P.F.2
  • 28
    • 21244480070 scopus 로고    scopus 로고
    • Expression of uncoupling protein 1 in skeletal muscle decreases muscle energy efficiency and affects thermoregulation and substrate oxidation
    • Klaus S, Rudolph B, Dohrmann C, Wehr R 2005 Expression of uncoupling protein 1 in skeletal muscle decreases muscle energy efficiency and affects thermoregulation and substrate oxidation. Physiol Genomics 21:193-200
    • (2005) Physiol Genomics , vol.21 , pp. 193-200
    • Klaus, S.1    Rudolph, B.2    Dohrmann, C.3    Wehr, R.4
  • 29
    • 4344698289 scopus 로고    scopus 로고
    • Frenz U 1999 Whole body calorimetry. In: Kemp RB, ed. Handbook of thermal analysis and calorimetry. 4: From macromolecules to man. Amsterdam: Elsevier; 511-555
    • Frenz U 1999 Whole body calorimetry. In: Kemp RB, ed. Handbook of thermal analysis and calorimetry. Vol. 4: From macromolecules to man. Amsterdam: Elsevier; 511-555
  • 30
    • 8544251324 scopus 로고    scopus 로고
    • Expression and regulation of multiple murine ATP-binding cassette transporter G1 mRNAs/isoforms that stimulate cellular cholesterol efflux to high density lipoprotein
    • Nakamura K, Kennedy MA, Baldan A, Bojanic DD, Lyons K, Edwards PA 2004 Expression and regulation of multiple murine ATP-binding cassette transporter G1 mRNAs/isoforms that stimulate cellular cholesterol efflux to high density lipoprotein. J Biol Chem 279:45980-45989
    • (2004) J Biol Chem , vol.279 , pp. 45980-45989
    • Nakamura, K.1    Kennedy, M.A.2    Baldan, A.3    Bojanic, D.D.4    Lyons, K.5    Edwards, P.A.6
  • 31
    • 0026783771 scopus 로고
    • Mechanism of hormone-stimulated lipolysis in adipocytes: Translocation of hormone-sensitive lipase to the lipid storage droplet
    • Egan JJ, Greenberg AS, Chang MK, Wek SA, Moos Jr MC, Londos C 1992 Mechanism of hormone-stimulated lipolysis in adipocytes: translocation of hormone-sensitive lipase to the lipid storage droplet. Proc Natl Acad Sci USA 89:8537-8541
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 8537-8541
    • Egan, J.J.1    Greenberg, A.S.2    Chang, M.K.3    Wek, S.A.4    Moos Jr, M.C.5    Londos, C.6
  • 32
    • 30044438117 scopus 로고    scopus 로고
    • Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormonesensitive lipase
    • Moore HP, Silver RB, Mottillo EP, Bernlohr DA, Granneman JG 2005 Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormonesensitive lipase. J Biol Chem 280:43109-43120
    • (2005) J Biol Chem , vol.280 , pp. 43109-43120
    • Moore, H.P.1    Silver, R.B.2    Mottillo, E.P.3    Bernlohr, D.A.4    Granneman, J.G.5
  • 33
    • 33744904687 scopus 로고    scopus 로고
    • The phosphorylation of serine 492 of perilipin A directs lipid droplet fragmentation and dispersion
    • Marcinkiewicz A, Gauthier D, Garcia A, Brasaemle DL 2006 The phosphorylation of serine 492 of perilipin A directs lipid droplet fragmentation and dispersion. J Biol Chem 281:11901-11909
    • (2006) J Biol Chem , vol.281 , pp. 11901-11909
    • Marcinkiewicz, A.1    Gauthier, D.2    Garcia, A.3    Brasaemle, D.L.4
  • 34
    • 0032561340 scopus 로고    scopus 로고
    • A carboxyl-terminal extension of the zinc finger domain contributes to the specificity and polarity of peroxisome proliferator-activated receptor DNA binding
    • Hsu MH, Palmer CN, Song W, Griffin KJ, Johnson EF 1998 A carboxyl-terminal extension of the zinc finger domain contributes to the specificity and polarity of peroxisome proliferator-activated receptor DNA binding. J Biol Chem 273:27988-27997
    • (1998) J Biol Chem , vol.273 , pp. 27988-27997
    • Hsu, M.H.1    Palmer, C.N.2    Song, W.3    Griffin, K.J.4    Johnson, E.F.5
  • 35
    • 14544296165 scopus 로고    scopus 로고
    • The role of the orphan nuclear receptor Rev-Erbα in adipocyte differentiation and function
    • Laitinene S, Tontaine C, Fruchart JC, Staels B 2005 The role of the orphan nuclear receptor Rev-Erbα in adipocyte differentiation and function. Biochimie 87:21-25
    • (2005) Biochimie , vol.87 , pp. 21-25
    • Laitinene, S.1    Tontaine, C.2    Fruchart, J.C.3    Staels, B.4
  • 39
    • 0037453718 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor δ activates fat metabolism to prevent obesity
    • Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H, Evans RM 2003 Peroxisome-proliferator-activated receptor δ activates fat metabolism to prevent obesity. Cell 113:159-170
    • (2003) Cell , vol.113 , pp. 159-170
    • Wang, Y.X.1    Lee, C.H.2    Tiep, S.3    Yu, R.T.4    Ham, J.5    Kang, H.6    Evans, R.M.7
  • 40
    • 0033787068 scopus 로고    scopus 로고
    • Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice
    • Li B, Nolte LA, Ju JS, Han DH, Coleman T, Holloszy JO, Semenkovich CF 2000 Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice. Nat Med 6:1115-1120
    • (2000) Nat Med , vol.6 , pp. 1115-1120
    • Li, B.1    Nolte, L.A.2    Ju, J.S.3    Han, D.H.4    Coleman, T.5    Holloszy, J.O.6    Semenkovich, C.F.7
  • 41
    • 0028865142 scopus 로고
    • Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity
    • Kopecky J, Clarke G, Enerback S, Spiegelman B, Kozak LP 1995 Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity. J Clin Invest 96:2914-2923
    • (1995) J Clin Invest , vol.96 , pp. 2914-2923
    • Kopecky, J.1    Clarke, G.2    Enerback, S.3    Spiegelman, B.4    Kozak, L.P.5
  • 42
    • 1442308949 scopus 로고    scopus 로고
    • Adipocyte cholesterol balance in obesity
    • Le Lay S, Ferre P, Dugail I 2004 Adipocyte cholesterol balance in obesity. Biochem Soc Trans 32:103-106
    • (2004) Biochem Soc Trans , vol.32 , pp. 103-106
    • Le Lay, S.1    Ferre, P.2    Dugail, I.3
  • 44
    • 12444296524 scopus 로고    scopus 로고
    • Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus
    • Heilbronn L, Smith SR, Ravussin E 2004 Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus. Int J Obes Relat Metab Disord 28(Suppl 4):S12-S21
    • (2004) Int J Obes Relat Metab Disord , vol.28 , Issue.SUPPL. 4
    • Heilbronn, L.1    Smith, S.R.2    Ravussin, E.3
  • 47
    • 0035430576 scopus 로고    scopus 로고
    • Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance
    • de Souza CJ, Eckhardt M, Gagen K, Dong M, Chen W, Laurent D, Burkey BF 2001 Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance. Diabetes 50:1863-1871
    • (2001) Diabetes , vol.50 , pp. 1863-1871
    • de Souza, C.J.1    Eckhardt, M.2    Gagen, K.3    Dong, M.4    Chen, W.5    Laurent, D.6    Burkey, B.F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.