-
1
-
-
48249087613
-
Correlation of T cell response and bacterial clearance in human volunteers challenged with Helicobacter pylori revealed by randomised controlled vaccination with Ty21a-based Salmonella vaccines
-
Aebischer T, Bumann D, Epple HJ et al (2008) Correlation of T cell response and bacterial clearance in human volunteers challenged with Helicobacter pylori revealed by randomised controlled vaccination with Ty21a-based Salmonella vaccines. Gut 57:1065–1072. doi:10.1136/gut.2007.145839.
-
(2008)
Gut
, vol.57
, pp. 1065-1072
-
-
Aebischer, T.1
Bumann, D.2
Epple, H.J.3
-
2
-
-
84905968839
-
A video protocol of retroviral infection in primary intestinal organoid culture
-
Andersson-Rolf A, Fink J, Mustata RC, Koo B-K (2014) A video protocol of retroviral infection in primary intestinal organoid culture. J Vis Exp. doi:10.3791/51765.
-
(2014)
J Vis Exp
-
-
Andersson-Rolf, A.1
Fink, J.2
Mustata, R.C.3
Koo, B.-K.4
-
3
-
-
80053914464
-
Sox2+ adult stem and progenitor cells are important for tissue regeneration and survival of mice
-
Arnold K, Sarkar A, Yram MA et al (2011) Sox2+ adult stem and progenitor cells are important for tissue regeneration and survival of mice. Cell Stem Cell 9:317–329. doi:10.1016/j.stem.2011.09.001.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 317-329
-
-
Arnold, K.1
Sarkar, A.2
Yram, M.A.3
-
4
-
-
77958165564
-
What a disorder: Proinflammatory signaling pathways induced by Helicobacter pylori
-
Backert S, Naumann M (2010) What a disorder: proinflammatory signaling pathways induced by Helicobacter pylori. Trends Microbiol 18(11):479–486. doi:10.1016/j.tim.2010.08.003.
-
(2010)
Trends Microbiol
, vol.18
, Issue.11
, pp. 479-486
-
-
Backert, S.1
Naumann, M.2
-
5
-
-
0034042694
-
Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus
-
Backert S, Ziska E, Brinkmann V et al (2000) Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus. Cell Microbiol 2:155–164. doi:10.1046/j.1462-5822.2000.00043.x
-
(2000)
Cell Microbiol
, vol.2
, pp. 155-164
-
-
Backert, S.1
Ziska, E.2
Brinkmann, V.3
-
6
-
-
84930981461
-
Composition, structure and function of the Helicobacter pylori cag pathogenicity island encoded type IV secretion system
-
Backert S, Tegtmeyer N, Fischer W (2015) Composition, structure and function of the Helicobacter pylori cag pathogenicity island encoded type IV secretion system. Future Microbiol 10(6):955–965. doi:10.2217/fmb.15.32.
-
(2015)
Future Microbiol
, vol.10
, Issue.6
, pp. 955-965
-
-
Backert, S.1
Tegtmeyer, N.2
Fischer, W.3
-
7
-
-
73049116186
-
+ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro
-
+ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 6:25–36. doi:10.1016/j.stem.2009.11.013.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 25-36
-
-
Barker, N.1
Huch, M.2
Kujala, P.3
-
8
-
-
84949431975
-
Organoids as model for infectious diseases: Culture of human and murine stomach organoids and microinjection of Helicobacter pylori
-
Bartfeld S, Clevers H (2015) Organoids as model for infectious diseases: culture of human and murine stomach organoids and microinjection of Helicobacter pylori. J Vis Exp. doi:10.3791/53359.
-
(2015)
J Vis Exp
-
-
Bartfeld, S.1
Clevers, H.2
-
9
-
-
77951166289
-
High-throughput and single-cell imaging of NF-kappaB oscillations using monoclonal cell lines
-
Bartfeld S, Hess S, Bauer B et al (2010) High-throughput and single-cell imaging of NF-kappaB oscillations using monoclonal cell lines. BMC Cell Biol 11:21. doi:10.1186/1471-2121-11-21.
-
(2010)
BMC Cell Biol
, vol.11
, pp. 21
-
-
Bartfeld, S.1
Hess, S.2
Bauer, B.3
-
10
-
-
84922875352
-
In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection
-
Bartfeld S, Bayram T, van de Wetering M et al (2015) In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection. Gastroenterology 148(126–136): e6. doi:10.1053/j.gastro.2014.09.042.
-
(2015)
Gastroenterology
, vol.148
, Issue.126-136
-
-
Bartfeld, S.1
Bayram, T.2
van de Wetering, M.3
-
11
-
-
85007560110
-
Adult gastric stem cells and their niches
-
Bartfeld S, Koo BK (2016). Adult gastric stem cells and their niches. WIREs Dev Biol. doi:10.1002/wdev.261.
-
(2016)
Wires Dev Biol
-
-
Bartfeld, S.1
Koo, B.K.2
-
12
-
-
84924365664
-
CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation
-
Bertaux-Skeirik N, Feng R, Schumacher MA et al (2015) CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation. PLoS Pathog 11:e1004663. doi:10.1371/journal.ppat.1004663.
-
(2015)
Plos Pathog
, pp. 11
-
-
Bertaux-Skeirik, N.1
Feng, R.2
Schumacher, M.A.3
-
13
-
-
0033587779
-
Dynamics of Helicobacter pylori colonization in relation to the host response
-
Blaser MJ, Kirschner D (1999) Dynamics of Helicobacter pylori colonization in relation to the host response. Proc Natl Acad Sci 96:8359–8364. doi:10.1073/pnas.96.15.8359.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 8359-8364
-
-
Blaser, M.J.1
Kirschner, D.2
-
14
-
-
0029043658
-
Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach
-
Blaser MJ, Perez-Perez GI, Kleanthous H et al (1995) Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 55:2111–2115.
-
(1995)
Cancer Res
, vol.55
, pp. 2111-2115
-
-
Blaser, M.J.1
Perez-Perez, G.I.2
Kleanthous, H.3
-
15
-
-
84920983131
-
Organoid models of human and mouse ductal pancreatic cancer
-
Boj SF, Hwang C-I, Baker LA et al (2015) Organoid models of human and mouse ductal pancreatic cancer. Cell 160:324–338. doi:10.1016/j.cell.2014.12.021.
-
(2015)
Cell
, vol.160
, pp. 324-338
-
-
Boj, S.F.1
Hwang, C.-I.2
Baker, L.A.3
-
16
-
-
0031408931
-
Isolation and culturing of highly polarized primary epithelial cells from normal human stomach (Antrum) as spheroid-like vesicles
-
Boxberger H-J, Sessler MJ, Grausam MC et al (1997) Isolation and culturing of highly polarized primary epithelial cells from normal human stomach (antrum) as spheroid-like vesicles. Methods Cell Sci 19:169–178. doi:10.1023/A:1009751913391.
-
(1997)
Methods Cell Sci
, vol.19
, pp. 169-178
-
-
Boxberger, H.-J.1
Sessler, M.J.2
Grausam, M.C.3
-
17
-
-
57849111930
-
The gastric epithelial progenitor cell niche and differentiation of the zymogenic (Chief) cell lineage
-
Bredemeyer AJ, Geahlen JH, Weis VG et al (2009) The gastric epithelial progenitor cell niche and differentiation of the zymogenic (chief) cell lineage. Dev Biol 325:211–224. doi:10.1016/j.ydbio.2008.10.025.
-
(2009)
Dev Biol
, vol.325
, pp. 211-224
-
-
Bredemeyer, A.J.1
Geahlen, J.H.2
Weis, V.G.3
-
18
-
-
84893196064
-
Cell lineage distribution atlas of the human stomach reveals heterogeneous gland populations in the gastric antrum
-
Choi E, Roland JT, Barlow BJ et al (2014) Cell lineage distribution atlas of the human stomach reveals heterogeneous gland populations in the gastric antrum. Gut 63:1711–1720. doi:10.1136/gutjnl-2013-305964.
-
(2014)
Gut
, vol.63
, pp. 1711-1720
-
-
Choi, E.1
Roland, J.T.2
Barlow, B.J.3
-
19
-
-
0037732638
-
Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response
-
Churin Y, Al-Ghoul L, Kepp O et al (2003) Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response. J Cell Biol 161:249–255. doi:10.1083/jcb. 200208039.
-
(2003)
J Cell Biol
, vol.161
, pp. 249-255
-
-
Churin, Y.1
Al-Ghoul, L.2
Kepp, O.3
-
20
-
-
0027173990
-
Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer
-
Covacci A, Censini S, Bugnoli M et al (1993) Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci 90:5791–5795.
-
(1993)
Proc Natl Acad Sci
, vol.90
, pp. 5791-5795
-
-
Covacci, A.1
Censini, S.2
Bugnoli, M.3
-
21
-
-
84964317107
-
Organoid models of human gastrointestinal development and disease
-
Dedhia PH, Bertaux-Skeirik N, Zavros Y, Spence JR (2016) Organoid models of human gastrointestinal development and disease. Gastroenterology 150:1098–1112. doi:10.1053/j.gastro.2015.12.042.
-
(2016)
Gastroenterology
, vol.150
, pp. 1098-1112
-
-
Dedhia, P.H.1
Bertaux-Skeirik, N.2
Zavros, Y.3
Spence, J.R.4
-
22
-
-
84944442090
-
Notch signaling regulates gastric antral LGR5 stem cell function
-
Demitrack ES, Gifford GB, Keeley TM et al (2015) Notch signaling regulates gastric antral LGR5 stem cell function. EMBO J 34:2522–2536. doi:10.15252/embj.201490583.
-
(2015)
EMBO J
, vol.34
, pp. 2522-2536
-
-
Demitrack, E.S.1
Gifford, G.B.2
Keeley, T.M.3
-
23
-
-
84929103936
-
Sequential cancer mutations in cultured human intestinal stem cells
-
Drost J, van Jaarsveld RH, Ponsioen B et al (2015) Sequential cancer mutations in cultured human intestinal stem cells. Nature 521:43–47. doi:10.1038/nature14415.
-
(2015)
Nature
, vol.521
, pp. 43-47
-
-
Drost, J.1
van Jaarsveld, R.H.2
Ponsioen, B.3
-
24
-
-
84959357347
-
Organoids as an in vitro model of human development and disease
-
Fatehullah A, Tan SH, Barker N (2016) Organoids as an in vitro model of human development and disease. Nat Cell Biol 18:246–254. doi:10.1038/ncb3312.
-
(2016)
Nat Cell Biol
, vol.18
, pp. 246-254
-
-
Fatehullah, A.1
Tan, S.H.2
Barker, N.3
-
25
-
-
84906938767
-
Indian hedgehog mediates gastrin-induced proliferation in stomach of adult mice
-
Feng R, Aihara E, Kenny S et al (2014) Indian hedgehog mediates gastrin-induced proliferation in stomach of adult mice. Gastroenterology 147(655–666):e9. doi:10.1053/j.gastro.2014.05.006.
-
(2014)
Gastroenterology
, vol.147
, Issue.655-666
, pp. 9
-
-
Feng, R.1
Aihara, E.2
Kenny, S.3
-
26
-
-
84971516758
-
A colorectal tumor organoid library demonstrates progressive loss of niche factor requirements during tumorigenesis
-
Fujii M, Shimokawa M, Date S et al (2016) A colorectal tumor organoid library demonstrates progressive loss of niche factor requirements during tumorigenesis. Cell Stem Cell. doi:10.1016/j.stem.2016.04.003.
-
(2016)
Cell Stem Cell
-
-
Fujii, M.1
Shimokawa, M.2
Date, S.3
-
27
-
-
0023493924
-
Proliferative effects of urogastrone-EGF on the intestinal epithelium
-
Goodlad RA, Wilson TJ, Lenton W et al (1987) Proliferative effects of urogastrone-EGF on the intestinal epithelium. Gut 28:37–43.
-
(1987)
Gut
, vol.28
, pp. 37-43
-
-
Goodlad, R.A.1
Wilson, T.J.2
Lenton, W.3
-
28
-
-
84954214835
-
Mist1 expressing gastric stem cells maintain the normal and neoplastic gastric epithelium and are supported by a perivascular stem cell niche
-
Hayakawa Y, Ariyama H, Stancikova J et al (2015a) Mist1 expressing gastric stem cells maintain the normal and neoplastic gastric epithelium and are supported by a perivascular stem cell niche. Cancer Cell 28:800–814. doi:10.1016/j.ccell.2015.10.003.
-
(2015)
Cancer Cell
, vol.28
, pp. 800-814
-
-
Hayakawa, Y.1
Ariyama, H.2
Stancikova, J.3
-
29
-
-
84924371079
-
CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis
-
Hayakawa Y, Jin G, Wang H et al (2015b) CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis. Gut 64:544–553. doi:10.1136/gutjnl-2014-307190.
-
(2015)
Gut
, vol.64
, pp. 544-553
-
-
Hayakawa, Y.1
Jin, G.2
Wang, H.3
-
30
-
-
0025343810
-
Bacterial adhesion and disease activity in Helicobacter associated chronic gastritis
-
Hessey SJ, Spencer J, Wyatt JI et al (1990) Bacterial adhesion and disease activity in Helicobacter associated chronic gastritis. Gut 31:134–138.
-
(1990)
Gut
, vol.31
, pp. 134-138
-
-
Hessey, S.J.1
Spencer, J.2
Wyatt, J.I.3
-
31
-
-
84942991269
-
Chemodetection and destruction of host urea allows Helicobacter pylori to locate the epithelium
-
Huang JY, Sweeney EG, Sigal M et al (2015) Chemodetection and destruction of host urea allows Helicobacter pylori to locate the epithelium. Cell Host Microbe 18:147–156. doi:10.1016/j. chom.2015.07.002.
-
(2015)
Cell Host Microbe
, vol.18
, pp. 147-156
-
-
Huang, J.Y.1
Sweeney, E.G.2
Sigal, M.3
-
32
-
-
84942121762
-
Modeling mouse and human development using organoid cultures
-
Huch M, Koo B-K (2015) Modeling mouse and human development using organoid cultures. Dev Camb Engl 142:3113–3125. doi:10.1242/dev.118570.
-
(2015)
Dev Camb Engl
, vol.142
, pp. 3113-3125
-
-
Huch, M.1
Koo, B.-K.2
-
33
-
-
84885846800
-
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis
-
Huch M, Bonfanti P, Boj SF et al (2013) Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis. EMBO J 32:2708–2721. doi:10.1038/emboj.2013.204.
-
(2013)
EMBO J
, vol.32
, pp. 2708-2721
-
-
Huch, M.1
Bonfanti, P.2
Boj, S.F.3
-
34
-
-
0027263559
-
Dynamics of epithelial cells in the corpus of the mouse stomach. IV. Bidirectional migration of parietal cells ending in their gradual degeneration and loss
-
Karam SM (1993) Dynamics of epithelial cells in the corpus of the mouse stomach. IV. Bidirectional migration of parietal cells ending in their gradual degeneration and loss. Anat Rec 236:314–332. doi:10.1002/ar.1092360205.
-
(1993)
Anat Rec
, vol.236
, pp. 314-332
-
-
Karam, S.M.1
-
35
-
-
0027174442
-
Dynamics of epithelial cells in the corpus of the mouse stomach. III. Inward migration of neck cells followed by progressive transformation into zymogenic cells
-
Karam SM, Leblond CP (1993a) Dynamics of epithelial cells in the corpus of the mouse stomach. III. Inward migration of neck cells followed by progressive transformation into zymogenic cells. Anat Rec 236:297–313. doi:10.1002/ar.1092360204.
-
(1993)
Anat Rec
, vol.236
, pp. 297-313
-
-
Karam, S.M.1
Leblond, C.P.2
-
36
-
-
0027195468
-
Dynamics of epithelial cells in the corpus of the mouse stomach. II. Outward migration of pit cells
-
Karam SM, Leblond CP (1993b) Dynamics of epithelial cells in the corpus of the mouse stomach. II. Outward migration of pit cells. Anat Rec 236:280–296. doi:10.1002/ar.1092360203.
-
(1993)
Anat Rec
, vol.236
, pp. 280-296
-
-
Karam, S.M.1
Leblond, C.P.2
-
37
-
-
84907552531
-
Identification of multipotent luminal progenitor cells in human prostate organoid cultures
-
Karthaus WR, Iaquinta PJ, Drost J et al (2014) Identification of multipotent luminal progenitor cells in human prostate organoid cultures. Cell 159:163–175. doi:10.1016/j.cell.2014.08.017.
-
(2014)
Cell
, vol.159
, pp. 163-175
-
-
Karthaus, W.R.1
Iaquinta, P.J.2
Drost, J.3
-
38
-
-
84875554273
-
Establishment of a long-term three-dimensional primary culture of mouse glandular stomach epithelial cells within the stem cell niche
-
Katano T, Ootani A, Mizoshita T et al (2013) Establishment of a long-term three-dimensional primary culture of mouse glandular stomach epithelial cells within the stem cell niche. Biochem Biophys Res Commun 432:558–563. doi:10.1016/j.bbrc.2013.02.051.
-
(2013)
Biochem Biophys Res Commun
, vol.432
, pp. 558-563
-
-
Katano, T.1
Ootani, A.2
Mizoshita, T.3
-
39
-
-
84949504069
-
The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids
-
Kessler M, Hoffmann K, Brinkmann V et al (2015) The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids. Nat Commun 6:8989. doi:10.1038/ncomms9989.
-
(2015)
Nat Commun
, vol.6
, pp. 8989
-
-
Kessler, M.1
Hoffmann, K.2
Brinkmann, V.3
-
40
-
-
84856490464
-
Controlled gene expression in primary Lgr5 organoid cultures
-
Koo B-K, Stange DE, Sato T et al (2012) Controlled gene expression in primary Lgr5 organoid cultures. Nat Methods 9:81–83. doi:10.1038/nmeth.1802.
-
(2012)
Nat Methods
, vol.9
, pp. 81-83
-
-
Koo, B.-K.1
Stange, D.E.2
Sato, T.3
-
41
-
-
84856090845
-
Lineage tracing
-
Kretzschmar K, Watt FM (2012) Lineage tracing. Cell 148:33–45. doi:10.1016/j.cell.2012.01.002.
-
(2012)
Cell
, vol.148
, pp. 33-45
-
-
Kretzschmar, K.1
Watt, F.M.2
-
42
-
-
84904396621
-
Organogenesis in a dish: Modeling development and disease using organoid technologies
-
Lancaster MA, Knoblich JA (2014) Organogenesis in a dish: modeling development and disease using organoid technologies. Science 345:1247125. doi:10.1126/science.1247125.
-
(2014)
Science
, vol.345
-
-
Lancaster, M.A.1
Knoblich, J.A.2
-
43
-
-
0031905670
-
Animal models for host-pathogen interaction studies
-
Lee A (1998) Animal models for host-pathogen interaction studies. Br Med Bull 54:163–173.
-
(1998)
Br Med Bull
, vol.54
, pp. 163-173
-
-
Lee, A.1
-
44
-
-
0021966480
-
Dynamic histology of the antral epithelium in the mouse stomach: IV. Ultrastructure and renewal of gland cells
-
Lee ER, Leblond CP (1985a) Dynamic histology of the antral epithelium in the mouse stomach: IV. Ultrastructure and renewal of gland cells. Am J Anat 172:241–259.
-
(1985)
Am J Anat
, vol.172
, pp. 241-259
-
-
Lee, E.R.1
Leblond, C.P.2
-
45
-
-
0021957288
-
Dynamic histology of the antral epithelium in the mouse stomach: II. Ultrastructure and renewal of isthmal cells
-
Lee ER, Leblond CP (1985b) Dynamic histology of the antral epithelium in the mouse stomach: II. Ultrastructure and renewal of isthmal cells. Am J Anat 172:205–224. doi:10.1002/aja.1001720304.
-
(1985)
Am J Anat
, vol.172
, pp. 205-224
-
-
Lee, E.R.1
Leblond, C.P.2
-
46
-
-
0020071305
-
Division of the mouse gastric mucosa into zymogenic and mucous regions on the basis of gland features
-
Lee ER, Trasler J, Dwivedi S, Leblond CP (1982) Division of the mouse gastric mucosa into zymogenic and mucous regions on the basis of gland features. Am J Anat 164:187–207. doi:10.1002/aja.1001640302.
-
(1982)
Am J Anat
, vol.164
, pp. 187-207
-
-
Lee, E.R.1
Trasler, J.2
Dwivedi, S.3
Leblond, C.P.4
-
47
-
-
84861972831
-
Wnt signaling through inhibition of b-Catenin degradation in an intact Axin1 complex
-
Li VSW, Ng SS, Boersema PJ et al (2012) Wnt signaling through inhibition of b-Catenin degradation in an intact Axin1 complex. Cell 149:1245–1256. doi:10.1016/j.cell.2012.05.002.
-
(2012)
Cell
, vol.149
, pp. 1245-1256
-
-
Li, V.1
Ng, S.S.2
Boersema, P.J.3
-
48
-
-
84904066077
-
Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture
-
Li X, Nadauld L, Ootani A et al (2014) Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture. Nat Med 20:769–777. doi:10.1038/nm.3585.
-
(2014)
Nat Med
, vol.20
, pp. 769-777
-
-
Li, X.1
Nadauld, L.2
Ootani, A.3
-
50
-
-
84924422753
-
Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids
-
Matano M, Date S, Shimokawa M et al (2015) Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids. Nat Med. doi:10.1038/nm.3802.
-
(2015)
Nat Med
-
-
Matano, M.1
Date, S.2
Shimokawa, M.3
-
51
-
-
80955137949
-
Generating human intestinal tissue from pluripotent stem cells in vitro
-
McCracken KW, Howell JC, Wells JM, Spence JR (2011) Generating human intestinal tissue from pluripotent stem cells in vitro. Nat Protoc 6:1920–1928. doi:10.1038/nprot.2011.410.
-
(2011)
Nat Protoc
, vol.6
, pp. 1920-1928
-
-
McCracken, K.W.1
Howell, J.C.2
Wells, J.M.3
Spence, J.R.4
-
52
-
-
84918561297
-
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
-
McCracken KW, Catá EM, Crawford CM et al (2014) Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. Nature 516:400–404. doi:10.1038/nature13863.
-
(2014)
Nature
, vol.516
, pp. 400-404
-
-
McCracken, K.W.1
Catá, E.M.2
Crawford, C.M.3
-
53
-
-
84937574058
-
Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract
-
Mills JC, Sansom OJ (2015) Reserve stem cells: differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract. Sci Signal 8:re8. doi:10.1126/scisignal.aaa7540.
-
(2015)
Sci Signal
, vol.8
-
-
Mills, J.C.1
Sansom, O.J.2
-
54
-
-
84859717291
-
C-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains
-
Mueller D, Tegtmeyer N, Brandt S, Yamaoka Y, De Poire E, Sgouras D, Wessler S, Torres J, Smolka A, Backert S (2012) c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains. J Clin Invest 122:1553–1566. doi:10.1172/JCI61143.
-
(2012)
J Clin Invest
, vol.122
, pp. 1553-1566
-
-
Mueller, D.1
Tegtmeyer, N.2
Brandt, S.3
Yamaoka, Y.4
de Poire, E.5
Sgouras, D.6
Wessler, S.7
Torres, J.8
Smolka, A.9
Backert, S.10
-
55
-
-
84938700713
-
Generation of stomach tissue from mouse embryonic stem cells
-
Noguchi TK, Ninomiya N, Sekine M et al (2015) Generation of stomach tissue from mouse embryonic stem cells. Nat Cell Biol 17:984–993. doi:10.1038/ncb3200.
-
(2015)
Nat Cell Biol
, vol.17
, pp. 984-993
-
-
Noguchi, T.K.1
Ninomiya, N.2
Sekine, M.3
-
56
-
-
84990068792
-
The Mongolian Gerbil: A robust model of Helicobacter pylori-induced gastric inflammation and cancer
-
Noto JM, Romero-Gallo J, Piazuelo MB, Peek RM (2016) The Mongolian Gerbil: a robust model of Helicobacter pylori-induced gastric inflammation and cancer. Methods Mol Biol Clifton NJ 1422:263–280. doi:10.1007/978-1-4939-3603-8_24.
-
(2016)
Methods Mol Biol Clifton NJ
, vol.1422
, pp. 263-280
-
-
Noto, J.M.1
Romero-Gallo, J.2
Piazuelo, M.B.3
Peek, R.M.4
-
57
-
-
33846910009
-
FGF10 signaling controls stomach morphogenesis
-
Nyeng P, Norgaard GA, Kobberup S, Jensen J (2007) FGF10 signaling controls stomach morphogenesis. Dev Biol 303:295–310. doi:10.1016/j.ydbio.2006.11.017.
-
(2007)
Dev Biol
, vol.303
, pp. 295-310
-
-
Nyeng, P.1
Norgaard, G.A.2
Kobberup, S.3
Jensen, J.4
-
58
-
-
0034685651
-
An air-liquid interface promotes the differentiation of gastric surface mucous cells (GSM06) in culture
-
Ootani A, Toda S, Fujimoto K, Sugihara H (2000) An air-liquid interface promotes the differentiation of gastric surface mucous cells (GSM06) in culture. Biochem Biophys Res Commun 271:741–746. doi:10.1006/bbrc.2000.2673.
-
(2000)
Biochem Biophys Res Commun
, vol.271
, pp. 741-746
-
-
Ootani, A.1
Toda, S.2
Fujimoto, K.3
Sugihara, H.4
-
59
-
-
0037906431
-
Foveolar differentiation of mouse gastric mucosa in vitro
-
Ootani A, Toda S, Fujimoto K, Sugihara H (2003) Foveolar differentiation of mouse gastric mucosa in vitro. Am J Pathol 162:1905–1912. doi:10.1016/S0002-9440(10)64324-6.
-
(2003)
Am J Pathol
, vol.162
, pp. 1905-1912
-
-
Ootani, A.1
Toda, S.2
Fujimoto, K.3
Sugihara, H.4
-
60
-
-
67349157318
-
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche
-
Ootani A, Li X, Sangiorgi E et al (2009) Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche. Nat Med 15:701–706. doi:10.1038/nm.1951.
-
(2009)
Nat Med
, vol.15
, pp. 701-706
-
-
Ootani, A.1
Li, X.2
Sangiorgi, E.3
-
61
-
-
84884996155
-
The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis
-
Posselt G, Backert S, Wessler S (2013) The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis. Cell Commun Signal CCS 11:77. doi:10.1186/1478-811x-11-77.
-
(2013)
Cell Commun Signal CCS
, vol.11
, pp. 77
-
-
Posselt, G.1
Backert, S.2
Wessler, S.3
-
62
-
-
36549009168
-
Prospective identification of a multilineage progenitor in murine stomach epithelium
-
Qiao XT, Ziel JW, McKimpson W et al (2007) Prospective identification of a multilineage progenitor in murine stomach epithelium. Gastroenterology 133(1989–1998):e3. doi:10.1053/j.gastro.2007.09.031.
-
(2007)
Gastroenterology
, vol.133
, Issue.1989-1998
-
-
Qiao, X.T.1
Ziel, J.W.2
McKimpson, W.3
-
63
-
-
84876688065
-
Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation
-
Radulescu S, Ridgway RA, Cordero J et al (2013) Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation. Oncogene 32:2048–2057. doi:10.1038/onc.2012.224.
-
(2013)
Oncogene
, vol.32
, pp. 2048-2057
-
-
Radulescu, S.1
Ridgway, R.A.2
Cordero, J.3
-
64
-
-
0031656148
-
Helicobacter pylori-infected human antral primary cell cultures: Effect on gastrin cell function
-
Richter-Dahlfors A, Heczko U, Meloche RM et al (1998) Helicobacter pylori-infected human antral primary cell cultures: effect on gastrin cell function. Am J Physiol 275:G393–G401.
-
(1998)
Am J Physiol
, vol.275
, pp. G393-G401
-
-
Richter-Dahlfors, A.1
Heczko, U.2
Meloche, R.M.3
-
65
-
-
84878760040
-
Growing self-organizing mini-guts from a single intestinal stem cell: Mechanism and applications
-
Sato T, Clevers H (2013) Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 340:1190–1194. doi:10.1126/science.1234852.
-
(2013)
Science
, vol.340
, pp. 1190-1194
-
-
Sato, T.1
Clevers, H.2
-
66
-
-
67349123408
-
Single Lgr5 stem cells build crypt villus structures in vitro without a mesenchymal niche
-
Sato T, Vries RG, Snippert HJ et al (2009) Single Lgr5 stem cells build crypt villus structures in vitro without a mesenchymal niche. Nature 459:262–265. doi:10.1038/nature07935.
-
(2009)
Nature
, vol.459
, pp. 262-265
-
-
Sato, T.1
Vries, R.G.2
Snippert, H.J.3
-
67
-
-
80054857419
-
Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and barrett’s epithelium
-
Sato T, Stange DE, Ferrante M et al (2011) Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and barrett’s epithelium. Gastroenterology 141:1762–1772. doi:10.1053/j.gastro.2011.07.050.
-
(2011)
Gastroenterology
, vol.141
, pp. 1762-1772
-
-
Sato, T.1
Stange, D.E.2
Ferrante, M.3
-
68
-
-
84930016564
-
Salmonella manipulation of host signaling pathways provokes cellular transformation associated with gallbladder carcinoma
-
Scanu T, Spaapen RM, Bakker JM et al (2015) Salmonella manipulation of host signaling pathways provokes cellular transformation associated with gallbladder carcinoma. Cell Host Microbe 17:763–774. doi:10.1016/j.chom.2015.05.002.
-
(2015)
Cell Host Microbe
, vol.17
, pp. 763-774
-
-
Scanu, T.1
Spaapen, R.M.2
Bakker, J.M.3
-
69
-
-
84958987439
-
A novel human gastric primary cell culture system for modelling Helicobacter pylori infection in vitro
-
Schlaermann P, Toelle B, Berger H et al (2016) A novel human gastric primary cell culture system for modelling Helicobacter pylori infection in vitro. Gut. doi:10.1136/gutjnl-2014-307949.
-
(2016)
Gut
-
-
Schlaermann, P.1
Toelle, B.2
Berger, H.3
-
70
-
-
1842788063
-
The spatial orientation of Helicobacter pylori in the gastric mucus
-
Schreiber S, Konradt M, Groll C et al (2004) The spatial orientation of Helicobacter pylori in the gastric mucus. Proc Natl Acad Sci USA 101:5024–5029. doi:10.1073/pnas.0308386101.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 5024-5029
-
-
Schreiber, S.1
Konradt, M.2
Groll, C.3
-
71
-
-
84927690290
-
The use of murine-derived fundic organoids in studies of gastric physiology: The use of fundic organoids
-
Schumacher MA, Aihara E, Feng R, et al (2015a) The use of murine-derived fundic organoids in studies of gastric physiology: the use of fundic organoids. J Physiol. doi:10.1113/jphysiol.2014.283028.
-
(2015)
J Physiol
-
-
Schumacher, M.A.1
Aihara, E.2
Feng, R.3
-
72
-
-
84920877107
-
Helicobacter pylori-induced sonic hedgehog expression is regulated by NFjB pathway activation: The use of a novel in vitro model to study epithelial response to infection
-
Schumacher MA, Feng R, Aihara E et al (2015b) Helicobacter pylori-induced sonic hedgehog expression is regulated by NFjB pathway activation: the use of a novel in vitro model to study epithelial response to infection. Helicobacter 20:19–28. doi:10.1111/hel.12152.
-
(2015)
Helicobacter
, vol.20
, pp. 19-28
-
-
Schumacher, M.A.1
Feng, R.2
Aihara, E.3
-
73
-
-
84885773392
-
Generation of BAC transgenic epithelial organoids
-
Schwank G, Andersson-Rolf A, Koo B-K et al (2013a) Generation of BAC transgenic epithelial organoids. PLoS ONE 8:e76871. doi:10.1371/journal.pone.0076871.
-
(2013)
Plos ONE
, pp. 8
-
-
Schwank, G.1
Ersson-Rolf, A.2
Koo, B.-K.3
-
74
-
-
84890033064
-
Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients
-
Schwank G, Koo B-K, Sasselli V et al (2013b) Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell 13:653–658. doi:10.1016/j.stem.2013.11.002.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 653-658
-
-
Schwank, G.1
Koo, B.-K.2
Sasselli, V.3
-
75
-
-
0036510363
-
Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo
-
Selbach M, Moese S, Hauck CR, Meyer TF, Backert S (2002) Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo. J Biol Chem 277:6775–6778. doi:10.1074/jbc.C100754200.
-
(2002)
J Biol Chem
, vol.277
, pp. 6775-6778
-
-
Selbach, M.1
Moese, S.2
Hauck, C.R.3
Meyer, T.F.4
Backert, S.5
-
76
-
-
0031816886
-
Bacterial factors and immune pathogenesis in Helicobacter pylori infection
-
Shimoyama T, Crabtree J (1998) Bacterial factors and immune pathogenesis in Helicobacter pylori infection. Gut 43:S2–S5.
-
(1998)
Gut
, vol.43
, pp. S2-S5
-
-
Shimoyama, T.1
Crabtree, J.2
-
77
-
-
84928393314
-
Bending gradients: How the intestinal stem cell gets its home
-
Shyer AE, Huycke TR, Lee C et al (2015) Bending gradients: how the intestinal stem cell gets its home. Cell 161:569–580. doi:10.1016/j.cell.2015.03.041.
-
(2015)
Cell
, vol.161
, pp. 569-580
-
-
Shyer, A.E.1
Huycke, T.R.2
Lee, C.3
-
78
-
-
84887613180
-
Helicobacter pylori induces type 4 secretion system-dependent, but CagA-independent activation of IjBs and NF-jB/RelA at early time points
-
Sokolova O, Borgmann M, Rieke C et al (2013) Helicobacter pylori induces type 4 secretion system-dependent, but CagA-independent activation of IjBs and NF-jB/RelA at early time points. Int J Med Microbiol 303:548–552. doi:10.1016/j.ijmm.2013.07.008.
-
(2013)
Int J Med Microbiol
, vol.303
, pp. 548-552
-
-
Sokolova, O.1
Borgmann, M.2
Rieke, C.3
-
79
-
-
84988557153
-
Animal models of Helicobacter pylori infection
-
Backert S, Yamaoka Y, Japan, Tokyo
-
Solnick JV, Eaton KA, Peek RM (2016) Animal models of Helicobacter pylori infection. In: Backert S, Yamaoka Y (eds) Helicobacter pylori research: from bench to bedside. Springer, Japan, Tokyo, pp 273–297. doi:10.1242/dmm.000364.
-
(2016)
Helicobacter Pylori Research: From Bench to Bedside. Springer
, pp. 273-297
-
-
Solnick, J.V.1
Eaton, K.A.2
Peek, R.M.3
-
80
-
-
84885672388
-
Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium
-
Stange DE, Koo B-K, Huch M et al (2013) Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium. Cell 155:357–368. doi:10.1016/j.cell.2013.09.008.
-
(2013)
Cell
, vol.155
, pp. 357-368
-
-
Stange, D.E.1
Koo, B.-K.2
Huch, M.3
-
81
-
-
78751560396
-
High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array
-
Tung Y-C, Hsiao AY, Allen SG et al (2011) High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array. The Analyst 136:473–478. doi:10.1039/c0an00609b
-
(2011)
The Analyst
, vol.136
, pp. 473-478
-
-
Tung, Y.-C.1
Hsiao, A.Y.2
Allen, S.G.3
-
82
-
-
84928974420
-
Prospective derivation of a living organoid biobank of colorectal cancer patients
-
Van de Wetering M, Francies HE, Francis JM et al (2015) Prospective derivation of a living organoid biobank of colorectal cancer patients. Cell 161:933–945. doi:10.1016/j.cell.2015.03.053.
-
(2015)
Cell
, vol.161
, pp. 933-945
-
-
van De Wetering, M.1
Francies, H.E.2
Francis, J.M.3
-
83
-
-
0034907949
-
Sonic hedgehog regulates gastric gland morphogenesis in man and mouse
-
Van Den Brink GR, Hardwick JCH, Peppelenbosch MP et al (2001) Sonic hedgehog regulates gastric gland morphogenesis in man and mouse. Gastroenterology 121:317–328. doi:10.1053/gast.2001.26261.
-
(2001)
Gastroenterology
, vol.121
, pp. 317-328
-
-
Van Den Brink, G.R.1
Hardwick, J.2
Peppelenbosch, M.P.3
-
84
-
-
84934985095
-
Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays
-
VanDussen KL, Marinshaw JM, Shaikh N et al (2015) Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays. Gut 64:911–920. doi:10.1136/gutjnl-2013-306651.
-
(2015)
Gut
, vol.64
, pp. 911-920
-
-
Vandussen, K.L.1
Marinshaw, J.M.2
Shaikh, N.3
-
85
-
-
0029861301
-
Processing and proliferative effects of human progastrin in transgenic mice
-
Wang TC, Koh TJ, Varro A et al (1996) Processing and proliferative effects of human progastrin in transgenic mice. J Clin Invest 98:1918–1929. doi:10.1172/JCI118993.
-
(1996)
J Clin Invest
, vol.98
, pp. 1918-1929
-
-
Wang, T.C.1
Koh, T.J.2
Varro, A.3
-
86
-
-
84920247287
-
Unidentified curved bacilli on gastric epithelium in active chronic gastritis
-
Warren JR, Marshall B (1983) Unidentified curved bacilli on gastric epithelium in active chronic gastritis. The Lancet 321:1273–1275. doi:10.1016/S0140-6736(83)92719-8.
-
(1983)
The Lancet
, vol.321
, pp. 1273-1275
-
-
Warren, J.R.1
Marshall, B.2
-
87
-
-
84893283877
-
How to make an intestine
-
Wells JM, Spence JR (2014) How to make an intestine. Development 141:752–760. doi:10.1242/dev.097386.
-
(2014)
Development
, vol.141
, pp. 752-760
-
-
Wells, J.M.1
Spence, J.R.2
-
88
-
-
85013211780
-
Organoids as model systems for gastrointestinal diseases: Tissue engineering meets genetic engineering
-
Werner K, Weitz J, Stange DE (2016) Organoids as model systems for gastrointestinal diseases: tissue engineering meets genetic engineering. Curr Pathobiol Rep 4:1–9. doi:10.1007/s40139-016-0100-z
-
(2016)
Curr Pathobiol Rep
, vol.4
, pp. 1-9
-
-
Werner, K.1
Weitz, J.2
Stange, D.E.3
-
89
-
-
84929660818
-
Helicobacter pylori targets cancer-associated apical-junctional constituents in gastroids and gastric epithelial cells
-
Wroblewski LE, Piazuelo MB, Chaturvedi R et al (2014) Helicobacter pylori targets cancer-associated apical-junctional constituents in gastroids and gastric epithelial cells. Gut. doi:10.1136/gutjnl-2014-307650.
-
(2014)
Gut
-
-
Wroblewski, L.E.1
Piazuelo, M.B.2
Chaturvedi, R.3
-
90
-
-
34250205971
-
AGS and other tissue culture cells can unknowingly be persistently infected with PIV5; a virus that blocks interferon signalling by degrading STAT1
-
Young DF, Carlos TS, Hagmaier K et al (2007) AGS and other tissue culture cells can unknowingly be persistently infected with PIV5; a virus that blocks interferon signalling by degrading STAT1. Virology 365:238–240. doi:10.1016/j.virol.2007.03.061.
-
(2007)
Virology
, vol.365
, pp. 238-240
-
-
Young, D.F.1
Carlos, T.S.2
Hagmaier, K.3
|