-
1
-
-
75149149098
-
Loss of parietal cell expression of sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells
-
Xiao C, Ogle SA, Schumacher MA, Orr-Asman MA, Miller ML, Lertkowit N, Varro A, Hollande F, Zavros Y. Loss of parietal cell expression of sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells. Gastroenterology 2010;138:550-61.
-
(2010)
Gastroenterology
, vol.138
, pp. 550-561
-
-
Xiao, C.1
Ogle, S.A.2
Schumacher, M.A.3
Orr-Asman, M.A.4
Miller, M.L.5
Lertkowit, N.6
Varro, A.7
Hollande, F.8
Zavros, Y.9
-
2
-
-
0036839405
-
Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract
-
van den Brink GR, Hardwick JC, Nielsen C, Xu C, ten Kate FJ, Glickman J, van Deventer SJ, Roberts DJ, Peppelenbosch MP. Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract. Gut 2002;51:628-33.
-
(2002)
Gut
, vol.51
, pp. 628-633
-
-
van den Brink, G.R.1
Hardwick, J.C.2
Nielsen, C.3
Xu, C.4
ten Kate, F.J.5
Glickman, J.6
van Deventer, S.J.7
Roberts, D.J.8
Peppelenbosch, M.P.9
-
3
-
-
51149106366
-
+-ATPase-containing membranes in gastric parietal cells and secreted with histamine stimulation
-
+-ATPase-containing membranes in gastric parietal cells and secreted with histamine stimulation. Am J Physiol 2008;295:G99-111.
-
(2008)
Am J Physiol
, vol.295
, pp. G99-111
-
-
Zavros, Y.1
Orr, M.A.2
Xiao, C.3
Malinowska, D.H.4
-
4
-
-
84862824410
-
Gastric sonic hedgehog acts as a macrophage chemoattractant during the immune response to Helicobacter pylori
-
Schumacher MA, Donnelly JM, Engevik AC, Xiao C, Yang L, Kenny S, Varro A, Hollande F, Samuelson LC, Zavros Y. Gastric sonic hedgehog acts as a macrophage chemoattractant during the immune response to Helicobacter pylori. Gastroenterology 2012;142:1150-9.
-
(2012)
Gastroenterology
, vol.142
, pp. 1150-1159
-
-
Schumacher, M.A.1
Donnelly, J.M.2
Engevik, A.C.3
Xiao, C.4
Yang, L.5
Kenny, S.6
Varro, A.7
Hollande, F.8
Samuelson, L.C.9
Zavros, Y.10
-
5
-
-
84871780214
-
Sonic Hedgehog contributes to gastric mucosal restitution after injury
-
Xiao C, Feng R, Engevik A, et al. Sonic Hedgehog contributes to gastric mucosal restitution after injury. Lab Invest 2013;93:96-111.
-
(2013)
Lab Invest
, vol.93
, pp. 96-111
-
-
Xiao, C.1
Feng, R.2
Engevik, A.3
-
6
-
-
84888272896
-
The acid-secreting parietal cell as an endocrine source of sonic hedgehog during gastric repair
-
Engevik AC, Feng R, Yang L, Zavros Y. The acid-secreting parietal cell as an endocrine source of sonic hedgehog during gastric repair. Endocrinology 2013;154:4627-39.
-
(2013)
Endocrinology
, vol.154
, pp. 4627-4639
-
-
Engevik, A.C.1
Feng, R.2
Yang, L.3
Zavros, Y.4
-
8
-
-
39149133212
-
NF-kappaB activation during acute Helicobacter pylori infection in mice
-
Ferrero RL, Avé P, Ndiaye D, Bambou JC, Huerre MR, Philpott DJ, Mémet S. NF-kappaB activation during acute Helicobacter pylori infection in mice. Infect Immun 2008;76:551-61.
-
(2008)
Infect Immun
, vol.76
, pp. 551-561
-
-
Ferrero, R.L.1
Avé, P.2
Ndiaye, D.3
Bambou, J.C.4
Huerre, M.R.5
Philpott, D.J.6
Mémet, S.7
-
9
-
-
21544441173
-
NF-kappaB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein
-
Brandt S, Kwok T, Hartig R, König W, Backert S. NF-kappaB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein. Proc Natl Acad Sci U S A 2005;102:9300-5.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9300-9305
-
-
Brandt, S.1
Kwok, T.2
Hartig, R.3
König, W.4
Backert, S.5
-
10
-
-
77951749929
-
Effect of Helicobacter pylori infection on the sonic hedgehog signaling pathway in gastric cancer cells
-
Kim JH, Choi YJ, Lee SH, Shin HS, Lee IO, Kim YJ, Kim H, Yang WI, Kim H, Lee YC. Effect of Helicobacter pylori infection on the sonic hedgehog signaling pathway in gastric cancer cells. Oncol Rep 2010;23:1523-8.
-
(2010)
Oncol Rep
, vol.23
, pp. 1523-1528
-
-
Kim, J.H.1
Choi, Y.J.2
Lee, S.H.3
Shin, H.S.4
Lee, I.O.5
Kim, Y.J.6
Kim, H.7
Yang, W.I.8
Kim, H.9
Lee, Y.C.10
-
11
-
-
84869068038
-
CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: implications for bidirectional tumor-stromal interactions
-
Singh AP, Arora S, Bhardwaj A, Srivastava SK, Kadakia MP, Wang B, Grizzle WE, Owen LB, Singh S. CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: implications for bidirectional tumor-stromal interactions. J Biol Chem 2012;287:39115-24.
-
(2012)
J Biol Chem
, vol.287
, pp. 39115-39124
-
-
Singh, A.P.1
Arora, S.2
Bhardwaj, A.3
Srivastava, S.K.4
Kadakia, M.P.5
Wang, B.6
Grizzle, W.E.7
Owen, L.B.8
Singh, S.9
-
12
-
-
84887833141
-
NOD2-nitric oxide-responsive microRNA-146a activates Sonic hedgehog signaling to orchestrate inflammatory responses in murine model of inflammatory bowel disease
-
Ghorpade DS, Sinha AY, Holla S, Singh V, Balaji KN. NOD2-nitric oxide-responsive microRNA-146a activates Sonic hedgehog signaling to orchestrate inflammatory responses in murine model of inflammatory bowel disease. J Biol Chem 2013;288:33037-48.
-
(2013)
J Biol Chem
, vol.288
, pp. 33037-33048
-
-
Ghorpade, D.S.1
Sinha, A.Y.2
Holla, S.3
Singh, V.4
Balaji, K.N.5
-
13
-
-
58249124375
-
Characterization of sonic hedgehog as a novel NF-kappaB target gene that promotes NF-kappaB-mediated apoptosis resistance and tumor growth in vivo
-
Kasperczyk H, Baumann B, Debatin KM, Fulda S. Characterization of sonic hedgehog as a novel NF-kappaB target gene that promotes NF-kappaB-mediated apoptosis resistance and tumor growth in vivo. FASEB J 2009;23:21-33.
-
(2009)
FASEB J
, vol.23
, pp. 21-33
-
-
Kasperczyk, H.1
Baumann, B.2
Debatin, K.M.3
Fulda, S.4
-
14
-
-
34250336769
-
De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis
-
El-Zaatari MTA, Grabowska AM, Kumari R, Scotting PJ, Kaye P, Atherton J, Clarke PA, Powe DG, Watson SA. De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis. Br J Cancer 2007;96:1855-61.
-
(2007)
Br J Cancer
, vol.96
, pp. 1855-1861
-
-
El-Zaatari, M.T.A.1
Grabowska, A.M.2
Kumari, R.3
Scotting, P.J.4
Kaye, P.5
Atherton, J.6
Clarke, P.A.7
Powe, D.G.8
Watson, S.A.9
-
15
-
-
73049116186
-
Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro
-
Barker N, Huch M, Kujala P, et al. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 2010;6:25-36.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 25-36
-
-
Barker, N.1
Huch, M.2
Kujala, P.3
-
16
-
-
84902654361
-
Establishment of gastrointestinal epithelial organoids
-
Mahe MM, Aihara E, Schumacher MA, Zavros Y, Montrose MH, Helmrath MA, Sato T, Shroyer NF. Establishment of gastrointestinal epithelial organoids. Curr Protoc Mouse Biol 2013;3:217-40.
-
(2013)
Curr Protoc Mouse Biol
, vol.3
, pp. 217-240
-
-
Mahe, M.M.1
Aihara, E.2
Schumacher, M.A.3
Zavros, Y.4
Montrose, M.H.5
Helmrath, M.A.6
Sato, T.7
Shroyer, N.F.8
-
17
-
-
84906938767
-
Indian hedgehog mediates gastrin-induced proliferation in stomach of adult mice
-
In Press.
-
Feng R, Aihara E, Kenny S, Yang L, Li J, Varro A, Montrose MH, Shroyer NF, Wang TC, Shivdasani RA, Zavros Y. Indian hedgehog mediates gastrin-induced proliferation in stomach of adult mice. Gastroenterology 2014;147:655-66, In Press.
-
(2014)
Gastroenterology
, vol.147
, pp. 655-666
-
-
Feng, R.1
Aihara, E.2
Kenny, S.3
Yang, L.4
Li, J.5
Varro, A.6
Montrose, M.H.7
Shroyer, N.F.8
Wang, T.C.9
Shivdasani, R.A.10
Zavros, Y.11
-
18
-
-
84885672388
-
Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium
-
Stange DE, Koo BK, Huch M, et al. Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium. Cell 2013;155:357-68.
-
(2013)
Cell
, vol.155
, pp. 357-368
-
-
Stange, D.E.1
Koo, B.K.2
Huch, M.3
-
19
-
-
0027173990
-
Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer
-
Covacci A, Censini S, Bugnoli M, et al. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci U S A 1993;90:5791-5.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 5791-5795
-
-
Covacci, A.1
Censini, S.2
Bugnoli, M.3
-
20
-
-
0029963677
-
cag, a pathogenicity island of Helicobacter pylori, encodes type I- specific and disease-associated virulence factors
-
Censini S, Lange C, Xiang Z, Crabtree JE, Ghiara P, Borodovsky M, Rappuoli R, Covacci A. cag, a pathogenicity island of Helicobacter pylori, encodes type I- specific and disease-associated virulence factors. Proc Natl Acad Sci U S A 1996;93:14648-53.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14648-14653
-
-
Censini, S.1
Lange, C.2
Xiang, Z.3
Crabtree, J.E.4
Ghiara, P.5
Borodovsky, M.6
Rappuoli, R.7
Covacci, A.8
-
21
-
-
0038780624
-
Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA
-
Amieva MR, Vogelmann R, Covacci A, Tompkins LS, Nelson WJ, Falkow S. Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Science 2003;300:1430-4.
-
(2003)
Science
, vol.300
, pp. 1430-1434
-
-
Amieva, M.R.1
Vogelmann, R.2
Covacci, A.3
Tompkins, L.S.4
Nelson, W.J.5
Falkow, S.6
-
22
-
-
4944245876
-
Phosphorylation-independent effects of CagA during interaction between Helicobacter pylori and T84 polarized monolayers
-
El-Etr SH, Mueller A, Tompkins LS, Falkow S, Merrell DS. Phosphorylation-independent effects of CagA during interaction between Helicobacter pylori and T84 polarized monolayers. J Infect Dis 2004;190:1516-23.
-
(2004)
J Infect Dis
, vol.190
, pp. 1516-1523
-
-
El-Etr, S.H.1
Mueller, A.2
Tompkins, L.S.3
Falkow, S.4
Merrell, D.S.5
-
23
-
-
0037069449
-
Cag pathogenicity island-specific responses of gastric epithelial cells to Helicobacter pylori infection
-
Guillemin K, Salama NR, Tompkins LS, Falkow S. Cag pathogenicity island-specific responses of gastric epithelial cells to Helicobacter pylori infection. Proc Natl Acad Sci U S A 2002;99:15136-41.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 15136-15141
-
-
Guillemin, K.1
Salama, N.R.2
Tompkins, L.S.3
Falkow, S.4
-
24
-
-
0033953359
-
Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation
-
Stein M, Rappuoli R, Covacci A. Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation. Proc Natl Acad Sci U S A 2000;97:1263-8.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 1263-1268
-
-
Stein, M.1
Rappuoli, R.2
Covacci, A.3
-
25
-
-
0033456273
-
Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori
-
Segal ED, Cha J, Lo J, Falkow S, Tompkins LS. Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori. Proc Natl Acad Sci U S A 1999;96:14559-64.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 14559-14564
-
-
Segal, E.D.1
Cha, J.2
Lo, J.3
Falkow, S.4
Tompkins, L.S.5
-
26
-
-
0030941212
-
A standardized mouse model of Helicobacter pylori infection: introducing the Sydney strain
-
Lee A, O'Rourke J, Ungria M, Robertson B, Daskalopoulos G, Dixon MF. A standardized mouse model of Helicobacter pylori infection: introducing the Sydney strain. Gastroenterology 1997;112:1386-97.
-
(1997)
Gastroenterology
, vol.112
, pp. 1386-1397
-
-
Lee, A.1
O'Rourke, J.2
Ungria, M.3
Robertson, B.4
Daskalopoulos, G.5
Dixon, M.F.6
-
27
-
-
42549128765
-
R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis
-
Bell SM, Schreiner CM, Wert SE, Mucenski ML, Scott WJ, Whitsett JA. R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis. Development 2008;135:1049-58.
-
(2008)
Development
, vol.135
, pp. 1049-1058
-
-
Bell, S.M.1
Schreiner, C.M.2
Wert, S.E.3
Mucenski, M.L.4
Scott, W.J.5
Whitsett, J.A.6
-
28
-
-
0036797045
-
Helicobacter pylori enter and survive within multivesicular vacuoles of epithelial cells
-
Amieva MR, Salama NR, Tompkins LS, Falkow S. Helicobacter pylori enter and survive within multivesicular vacuoles of epithelial cells. Cell Microbiol 2002;4:677-90.
-
(2002)
Cell Microbiol
, vol.4
, pp. 677-690
-
-
Amieva, M.R.1
Salama, N.R.2
Tompkins, L.S.3
Falkow, S.4
-
31
-
-
84887577062
-
Loss of NHE3 alters gut microbiota composition and influences Bacteroides thetaiotaomicron growth
-
Engevik MA, Aihara E, Montrose MH, Shull GE, Hassett DJ, Worrell RT. Loss of NHE3 alters gut microbiota composition and influences Bacteroides thetaiotaomicron growth. Am J Physiol Gastrointest Liver Physiol 2013;305:G697-711.
-
(2013)
Am J Physiol Gastrointest Liver Physiol
, vol.305
, pp. G697-G711
-
-
Engevik, M.A.1
Aihara, E.2
Montrose, M.H.3
Shull, G.E.4
Hassett, D.J.5
Worrell, R.T.6
-
32
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak K, Schmittgen T. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25:402-8.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.1
Schmittgen, T.2
-
33
-
-
19944381545
-
Down-regulation of a morphogen (sonic hedgehog) gradient in the gastric epithelium of Helicobacter pylori-infected Mongolian gerbils
-
Suzuki H, Minegishi Y, Nomoto Y, Ota T, Masaoka T, van den Brink GR, Hibi T. Down-regulation of a morphogen (sonic hedgehog) gradient in the gastric epithelium of Helicobacter pylori-infected Mongolian gerbils. J Pathol 2005;206:186-97.
-
(2005)
J Pathol
, vol.206
, pp. 186-197
-
-
Suzuki, H.1
Minegishi, Y.2
Nomoto, Y.3
Ota, T.4
Masaoka, T.5
van den Brink, G.R.6
Hibi, T.7
-
34
-
-
16844362860
-
Evidence that loss of sonic hedgehog is an indicator of Helicobater pylori-induced atrophic gastritis progressing to gastric cancer
-
Shiotani A, Iishi H, Uedo N, Ishiguro S, Tatsuta M, Nakae Y, Kumamoto M, Merchant JL. Evidence that loss of sonic hedgehog is an indicator of Helicobater pylori-induced atrophic gastritis progressing to gastric cancer. Am J Gastroenterol 2005;100:581-7.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 581-587
-
-
Shiotani, A.1
Iishi, H.2
Uedo, N.3
Ishiguro, S.4
Tatsuta, M.5
Nakae, Y.6
Kumamoto, M.7
Merchant, J.L.8
-
35
-
-
38149027631
-
Cyclopamine inhibition of the sonic hedgehog pathway in the stomach requires concomitant acid inhibition
-
El-Zaatari MGA, McKenzie AJ, Powe DG, Scotting PJ, Watson SA. Cyclopamine inhibition of the sonic hedgehog pathway in the stomach requires concomitant acid inhibition. Regul Pept 2008;146:131-9.
-
(2008)
Regul Pept
, vol.146
, pp. 131-139
-
-
El-Zaatari, M.G.A.1
McKenzie, A.J.2
Powe, D.G.3
Scotting, P.J.4
Watson, S.A.5
-
36
-
-
0037044575
-
The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation
-
Hoffmann A, Levchenko A, Scott ML, Baltimore D. The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science 2002;298:1241-5.
-
(2002)
Science
, vol.298
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
Baltimore, D.4
-
37
-
-
0030772159
-
Helicobacter pylori infection activates NF-kB in gastric epithelial cells
-
Keates S, Hitti YS, Upton M, Kelly CP. Helicobacter pylori infection activates NF-kB in gastric epithelial cells. Gastroenterology 1997;113:1099-109.
-
(1997)
Gastroenterology
, vol.113
, pp. 1099-1109
-
-
Keates, S.1
Hitti, Y.S.2
Upton, M.3
Kelly, C.P.4
-
38
-
-
0029561158
-
Heightened inflammatory response and cytokine expression in vivo to cagA+ Helicobacter pylori strains
-
Peek RM Jr., Miller GG, Tham KT, Perez-Perez GI, Zhao X, Atherton JC, Blaser MJ. Heightened inflammatory response and cytokine expression in vivo to cagA+ Helicobacter pylori strains. Lab Invest 1995;73:760-70.
-
(1995)
Lab Invest
, vol.73
, pp. 760-770
-
-
Peek Jr., R.M.1
Miller, G.G.2
Tham, K.T.3
Perez-Perez, G.I.4
Zhao, X.5
Atherton, J.C.6
Blaser, M.J.7
-
39
-
-
0029043658
-
Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach
-
Blaser JM, Perez-Perez GI, Kleanthous H, et al. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995;55:2111-5.
-
(1995)
Cancer Res
, vol.55
, pp. 2111-2115
-
-
Blaser, J.M.1
Perez-Perez, G.I.2
Kleanthous, H.3
|