메뉴 건너뛰기




Volumn 275, Issue 1, 2017, Pages 33-48

B-cell responses to HIV infection

Author keywords

B cells; HIV; HIV specific humoral immunity; pathogenesis; persisting viremia

Indexed keywords

GLYCOPROTEIN GP 140; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NEUTRALIZING ANTIBODY;

EID: 85010869940     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/imr.12502     Document Type: Review
Times cited : (129)

References (173)
  • 2
    • 84930392104 scopus 로고    scopus 로고
    • Checkpoints that control B cell development
    • Melchers F. Checkpoints that control B cell development. J Clin Invest. 2015;125:2203–2210.
    • (2015) J Clin Invest , vol.125 , pp. 2203-2210
    • Melchers, F.1
  • 3
    • 84901258891 scopus 로고    scopus 로고
    • Differences in mouse and human nonmemory B cell pools
    • Benitez A, Weldon AJ, Tatosyan L, et al. Differences in mouse and human nonmemory B cell pools. J Immunol. 2014;192:4610–4619.
    • (2014) J Immunol , vol.192 , pp. 4610-4619
    • Benitez, A.1    Weldon, A.J.2    Tatosyan, L.3
  • 4
    • 33144461111 scopus 로고    scopus 로고
    • Appearance of immature/transitional B cells in HIV-infected individuals with advanced disease: correlation with increased IL-7
    • Malaspina A, Moir S, Ho J, et al. Appearance of immature/transitional B cells in HIV-infected individuals with advanced disease: correlation with increased IL-7. Proc Natl Acad Sci U S A. 2006;103:2262–2267.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2262-2267
    • Malaspina, A.1    Moir, S.2    Ho, J.3
  • 5
    • 0035478494 scopus 로고    scopus 로고
    • Bm1-Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjogren's syndrome
    • Bohnhorst JO, Bjorgan MB, Thoen JE, Natvig JB, Thompson KM. Bm1-Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjogren's syndrome. J Immunol. 2001;167:3610–3618.
    • (2001) J Immunol , vol.167 , pp. 3610-3618
    • Bohnhorst, J.O.1    Bjorgan, M.B.2    Thoen, J.E.3    Natvig, J.B.4    Thompson, K.M.5
  • 6
    • 0034278588 scopus 로고    scopus 로고
    • Circulating human B cells that express surrogate light chains and edited receptors
    • Meffre E, Davis E, Schiff C, et al. Circulating human B cells that express surrogate light chains and edited receptors. Nat Immunol. 2000;1:207–213.
    • (2000) Nat Immunol , vol.1 , pp. 207-213
    • Meffre, E.1    Davis, E.2    Schiff, C.3
  • 7
    • 19344376101 scopus 로고    scopus 로고
    • Identification and characterization of circulating human transitional B cells
    • Sims GP, Ettinger R, Shirota Y, Yarboro CH, Illei GG, Lipsky PE. Identification and characterization of circulating human transitional B cells. Blood. 2005;105:4390–4398.
    • (2005) Blood , vol.105 , pp. 4390-4398
    • Sims, G.P.1    Ettinger, R.2    Shirota, Y.3    Yarboro, C.H.4    Illei, G.G.5    Lipsky, P.E.6
  • 8
    • 33847401590 scopus 로고    scopus 로고
    • + T lymphocytopenia is associated with increases in immature/transitional B cells and serum levels of IL-7
    • + T lymphocytopenia is associated with increases in immature/transitional B cells and serum levels of IL-7. Blood. 2007;109:2086–2088.
    • (2007) Blood , vol.109 , pp. 2086-2088
    • Malaspina, A.1    Moir, S.2    Chaitt, D.G.3
  • 9
    • 72449140060 scopus 로고    scopus 로고
    • Novel human transitional B cell populations revealed by B cell depletion therapy
    • Palanichamy A, Barnard J, Zheng B, et al. Novel human transitional B cell populations revealed by B cell depletion therapy. J Immunol. 2009;182:5982–5993.
    • (2009) J Immunol , vol.182 , pp. 5982-5993
    • Palanichamy, A.1    Barnard, J.2    Zheng, B.3
  • 10
    • 84955185358 scopus 로고    scopus 로고
    • Autoimmune Disease in Primary Immunodeficiency: At the Crossroads of Anti-Infective Immunity and Self-Tolerance
    • Saifi M, Wysocki CA. Autoimmune Disease in Primary Immunodeficiency: At the Crossroads of Anti-Infective Immunity and Self-Tolerance. Immunol Allergy Clin North Am. 2015;35:731–752.
    • (2015) Immunol Allergy Clin North Am , vol.35 , pp. 731-752
    • Saifi, M.1    Wysocki, C.A.2
  • 11
    • 0020516865 scopus 로고
    • Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome
    • Lane HC, Masur H, Edgar LC, Whalen G, Rook AH, Fauci AS. Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome. N Engl J Med. 1983;309:453–458.
    • (1983) N Engl J Med , vol.309 , pp. 453-458
    • Lane, H.C.1    Masur, H.2    Edgar, L.C.3    Whalen, G.4    Rook, A.H.5    Fauci, A.S.6
  • 12
    • 4544264445 scopus 로고    scopus 로고
    • Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily
    • Moir S, Malaspina A, Pickeral OK, et al. Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily. J Exp Med. 2004;200:587–599.
    • (2004) J Exp Med , vol.200 , pp. 587-599
    • Moir, S.1    Malaspina, A.2    Pickeral, O.K.3
  • 13
    • 80053399756 scopus 로고    scopus 로고
    • Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis
    • van Grevenynghe J, Cubas RA, Noto A, et al. Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis. J Clin Invest. 2011;121:3877–3888.
    • (2011) J Clin Invest , vol.121 , pp. 3877-3888
    • van Grevenynghe, J.1    Cubas, R.A.2    Noto, A.3
  • 14
    • 46049112339 scopus 로고    scopus 로고
    • Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals
    • Moir S, Ho J, Malaspina A, et al. Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. J Exp Med. 2008;205:1797–1805.
    • (2008) J Exp Med , vol.205 , pp. 1797-1805
    • Moir, S.1    Ho, J.2    Malaspina, A.3
  • 15
    • 68049135892 scopus 로고    scopus 로고
    • Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection
    • Levesque MC, Moody MA, Hwang KK, et al. Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection. PLoS Med. 2009;6:e1000107.
    • (2009) PLoS Med , vol.6
    • Levesque, M.C.1    Moody, M.A.2    Hwang, K.K.3
  • 16
    • 84885743368 scopus 로고    scopus 로고
    • + memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses
    • + memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses. Immunity. 2013;39:758–769.
    • (2013) Immunity , vol.39 , pp. 758-769
    • Locci, M.1    Havenar-Daughton, C.2    Landais, E.3
  • 17
    • 79958074866 scopus 로고    scopus 로고
    • Upregulation of IL-21 receptor on B cells and IL-21 secretion distinguishes novel 2009 H1N1 vaccine responders from nonresponders among HIV-infected persons on combination antiretroviral therapy
    • Pallikkuth S, Pilakka Kanthikeel S, Silva SY, et al. Upregulation of IL-21 receptor on B cells and IL-21 secretion distinguishes novel 2009 H1N1 vaccine responders from nonresponders among HIV-infected persons on combination antiretroviral therapy. J Immunol. 2011;186:6173–6181.
    • (2011) J Immunol , vol.186 , pp. 6173-6181
    • Pallikkuth, S.1    Pilakka Kanthikeel, S.2    Silva, S.Y.3
  • 18
    • 84878454838 scopus 로고    scopus 로고
    • Inadequate T follicular cell help impairs B cell immunity during HIV infection
    • Cubas RA, Mudd JC, Savoye AL, et al. Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nat Med. 2013;19:494–499.
    • (2013) Nat Med , vol.19 , pp. 494-499
    • Cubas, R.A.1    Mudd, J.C.2    Savoye, A.L.3
  • 19
    • 84962558674 scopus 로고    scopus 로고
    • A lymphomagenic role for HIV beyond immune suppression?
    • Dolcetti R, Gloghini A, Caruso A, Carbone A. A lymphomagenic role for HIV beyond immune suppression? Blood. 2016;127:1403–1409.
    • (2016) Blood , vol.127 , pp. 1403-1409
    • Dolcetti, R.1    Gloghini, A.2    Caruso, A.3    Carbone, A.4
  • 20
    • 84903765782 scopus 로고    scopus 로고
    • Abnormal B cell memory subsets dominate HIV-specific responses in infected individuals
    • Kardava L, Moir S, Shah N, et al. Abnormal B cell memory subsets dominate HIV-specific responses in infected individuals. J Clin Invest. 2014;124:3252–3262.
    • (2014) J Clin Invest , vol.124 , pp. 3252-3262
    • Kardava, L.1    Moir, S.2    Shah, N.3
  • 21
    • 84923814773 scopus 로고    scopus 로고
    • Antibody B cell responses in HIV-1 infection
    • Mouquet H. Antibody B cell responses in HIV-1 infection. Trends Immunol. 2014;35:549–561.
    • (2014) Trends Immunol , vol.35 , pp. 549-561
    • Mouquet, H.1
  • 22
    • 33748176405 scopus 로고    scopus 로고
    • Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection
    • Titanji K, De Milito A, Cagigi A, et al. Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection. Blood. 2006;108:1580–1587.
    • (2006) Blood , vol.108 , pp. 1580-1587
    • Titanji, K.1    De Milito, A.2    Cagigi, A.3
  • 23
    • 34250176946 scopus 로고    scopus 로고
    • Loss of discrete memory B cell subsets is associated with impaired immunization responses in HIV-1 infection and may be a risk factor for invasive pneumococcal disease
    • Hart M, Steel A, Clark SA, et al. Loss of discrete memory B cell subsets is associated with impaired immunization responses in HIV-1 infection and may be a risk factor for invasive pneumococcal disease. J. Immunol. 2007;178:8212–8220.
    • (2007) J. Immunol , vol.178 , pp. 8212-8220
    • Hart, M.1    Steel, A.2    Clark, S.A.3
  • 24
    • 78650440267 scopus 로고    scopus 로고
    • B cells in early and chronic HIV infection: evidence for preservation of immune function associated with early initiation of antiretroviral therapy
    • Moir S, Buckner CM, Ho J, et al. B cells in early and chronic HIV infection: evidence for preservation of immune function associated with early initiation of antiretroviral therapy. Blood. 2010;116:5571–5579.
    • (2010) Blood , vol.116 , pp. 5571-5579
    • Moir, S.1    Buckner, C.M.2    Ho, J.3
  • 25
    • 85010899527 scopus 로고    scopus 로고
    • HIV-dependent depletion of influenza-specific memory B cells impacts B cell responsiveness to seasonal influenza immunisation
    • Wheatley AK, Kristensen AB, Lay WN, Kent SJ. HIV-dependent depletion of influenza-specific memory B cells impacts B cell responsiveness to seasonal influenza immunisation. Sci Rep. 2016;6:26478.
    • (2016) Sci Rep , vol.6 , pp. 26478
    • Wheatley, A.K.1    Kristensen, A.B.2    Lay, W.N.3    Kent, S.J.4
  • 26
    • 33845876648 scopus 로고    scopus 로고
    • Two overrepresented B cell populations in HIV-infected individuals undergo apoptosis by different mechanisms
    • Ho J, Moir S, Malaspina A, et al. Two overrepresented B cell populations in HIV-infected individuals undergo apoptosis by different mechanisms. Proc Natl Acad Sci USA. 2006;103:19436–19441.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 19436-19441
    • Ho, J.1    Moir, S.2    Malaspina, A.3
  • 28
    • 21344434534 scopus 로고    scopus 로고
    • Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies
    • Haynes BF, Fleming J, St Clair EW, et al. Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies. Science. 2005;308:1906–1908.
    • (2005) Science , vol.308 , pp. 1906-1908
    • Haynes, B.F.1    Fleming, J.2    St Clair, E.W.3
  • 29
    • 84898463606 scopus 로고    scopus 로고
    • Autoreactivity in HIV-1 broadly neutralizing antibodies: implications for their function and induction by vaccination
    • Verkoczy L, Diaz M. Autoreactivity in HIV-1 broadly neutralizing antibodies: implications for their function and induction by vaccination. Curr Opin HIV AIDS. 2014;9:224–234.
    • (2014) Curr Opin HIV AIDS , vol.9 , pp. 224-234
    • Verkoczy, L.1    Diaz, M.2
  • 30
    • 0034605036 scopus 로고    scopus 로고
    • B cells of HIV-1-infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cells
    • Moir S, Malaspina A, Li Y, et al. B cells of HIV-1-infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cells. J Exp Med. 2000;192:637–646.
    • (2000) J Exp Med , vol.192 , pp. 637-646
    • Moir, S.1    Malaspina, A.2    Li, Y.3
  • 31
    • 84953281245 scopus 로고    scopus 로고
    • Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes
    • Heesters BA, Lindqvist M, Vagefi PA, et al. Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes. PLoS Pathog. 2015;11:e1005285.
    • (2015) PLoS Pathog , vol.11
    • Heesters, B.A.1    Lindqvist, M.2    Vagefi, P.A.3
  • 32
    • 84888009485 scopus 로고    scopus 로고
    • The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-beta1 production and FcRL4 expression
    • Jelicic K, Cimbro R, Nawaz F, et al. The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-beta1 production and FcRL4 expression. Nat Immunol. 2013;14:1256–1265.
    • (2013) Nat Immunol , vol.14 , pp. 1256-1265
    • Jelicic, K.1    Cimbro, R.2    Nawaz, F.3
  • 33
    • 69049119032 scopus 로고    scopus 로고
    • HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits
    • Xu W, Santini PA, Sullivan JS, et al. HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits. Nat Immunol. 2009;10:1008–1017.
    • (2009) Nat Immunol , vol.10 , pp. 1008-1017
    • Xu, W.1    Santini, P.A.2    Sullivan, J.S.3
  • 34
    • 0038342442 scopus 로고    scopus 로고
    • HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection
    • Swingler S, Brichacek B, Jacque JM, Ulich C, Zhou J, Stevenson M. HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection. Nature. 2003;424:213–219.
    • (2003) Nature , vol.424 , pp. 213-219
    • Swingler, S.1    Brichacek, B.2    Jacque, J.M.3    Ulich, C.4    Zhou, J.5    Stevenson, M.6
  • 35
    • 33947431615 scopus 로고    scopus 로고
    • Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion
    • van Zelm MC, Szczepanski T, van der Burg M, van Dongen JJ. Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion. J Exp Med. 2007;204:645–655.
    • (2007) J Exp Med , vol.204 , pp. 645-655
    • van Zelm, M.C.1    Szczepanski, T.2    van der Burg, M.3    van Dongen, J.J.4
  • 36
    • 80052171651 scopus 로고    scopus 로고
    • Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways
    • Berkowska MA, Driessen GJ, Bikos V, et al. Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways. Blood. 2011;118:2150–2158.
    • (2011) Blood , vol.118 , pp. 2150-2158
    • Berkowska, M.A.1    Driessen, G.J.2    Bikos, V.3
  • 37
    • 84923813876 scopus 로고    scopus 로고
    • Dynamics of B cells in germinal centres
    • De Silva NS, Klein U. Dynamics of B cells in germinal centres. Nat Rev Immunol. 2015;15:137–148.
    • (2015) Nat Rev Immunol , vol.15 , pp. 137-148
    • De Silva, N.S.1    Klein, U.2
  • 39
    • 84958831765 scopus 로고    scopus 로고
    • A temporal switch in the germinal center determines differential output of memory B and plasma cells
    • Weisel FJ, Zuccarino-Catania GV, Chikina M, Shlomchik MJ. A temporal switch in the germinal center determines differential output of memory B and plasma cells. Immunity. 2016;44:116–130.
    • (2016) Immunity , vol.44 , pp. 116-130
    • Weisel, F.J.1    Zuccarino-Catania, G.V.2    Chikina, M.3    Shlomchik, M.J.4
  • 40
    • 84908428884 scopus 로고    scopus 로고
    • Plasticity and complexity of B cell responses against persisting pathogens
    • Perez-Shibayama C, Gil-Cruz C, Ludewig B. Plasticity and complexity of B cell responses against persisting pathogens. Immunol Lett. 2014;162:53–58.
    • (2014) Immunol Lett , vol.162 , pp. 53-58
    • Perez-Shibayama, C.1    Gil-Cruz, C.2    Ludewig, B.3
  • 41
    • 84884499482 scopus 로고    scopus 로고
    • Impairment of B-cell functions during HIV-1 infection
    • Amu S, Ruffin N, Rethi B, Chiodi F. Impairment of B-cell functions during HIV-1 infection. AIDS. 2013;27:2323–2334.
    • (2013) AIDS , vol.27 , pp. 2323-2334
    • Amu, S.1    Ruffin, N.2    Rethi, B.3    Chiodi, F.4
  • 42
    • 84879284427 scopus 로고    scopus 로고
    • Insights into B cells and HIV-specific B-cell responses in HIV-infected individuals
    • Moir S, Fauci AS. Insights into B cells and HIV-specific B-cell responses in HIV-infected individuals. Immunol Rev. 2013;254:207–224.
    • (2013) Immunol Rev , vol.254 , pp. 207-224
    • Moir, S.1    Fauci, A.S.2
  • 43
    • 84866679186 scopus 로고    scopus 로고
    • Tools to therapeutically harness the human antibody response
    • Wilson PC, Andrews SF. Tools to therapeutically harness the human antibody response. Nat Rev Immunol. 2012;12:709–719.
    • (2012) Nat Rev Immunol , vol.12 , pp. 709-719
    • Wilson, P.C.1    Andrews, S.F.2
  • 44
    • 84883801440 scopus 로고    scopus 로고
    • Diversity among memory B cells: origin, consequences, and utility
    • Tarlinton D, Good-Jacobson K. Diversity among memory B cells: origin, consequences, and utility. Science. 2013;341:1205–1211.
    • (2013) Science , vol.341 , pp. 1205-1211
    • Tarlinton, D.1    Good-Jacobson, K.2
  • 45
    • 0032476611 scopus 로고    scopus 로고
    • + peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells
    • + peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. J Exp Med. 1998;188:1679–1689.
    • (1998) J Exp Med , vol.188 , pp. 1679-1689
    • Klein, U.1    Rajewsky, K.2    Kuppers, R.3
  • 46
    • 33748509736 scopus 로고    scopus 로고
    • + B cell population in peripheral blood expressing VH genes with low frequency of somatic mutation
    • + B cell population in peripheral blood expressing VH genes with low frequency of somatic mutation. J Immunol. 2006;177:3728–3736.
    • (2006) J Immunol , vol.177 , pp. 3728-3736
    • Fecteau, J.F.1    Cote, G.2    Neron, S.3
  • 49
    • 25144475070 scopus 로고    scopus 로고
    • Expression of the immunoregulatory molecule FcRH4 defines a distinctive tissue-based population of memory B cells
    • Ehrhardt GR, Hsu JT, Gartland L, et al. Expression of the immunoregulatory molecule FcRH4 defines a distinctive tissue-based population of memory B cells. J Exp Med. 2005;202:783–791.
    • (2005) J Exp Med , vol.202 , pp. 783-791
    • Ehrhardt, G.R.1    Hsu, J.T.2    Gartland, L.3
  • 50
    • 35349014587 scopus 로고    scopus 로고
    • Molecular Signature of CD8(+) T Cell Exhaustion during Chronic Viral Infection
    • Wherry EJ, Ha SJ, Kaech SM, et al. Molecular Signature of CD8(+) T Cell Exhaustion during Chronic Viral Infection. Immunity. 2007;27:670–684.
    • (2007) Immunity , vol.27 , pp. 670-684
    • Wherry, E.J.1    Ha, S.J.2    Kaech, S.M.3
  • 51
    • 84940118728 scopus 로고    scopus 로고
    • Age-Associated B Cells: A T-bet-Dependent effector with roles in protective and pathogenic immunity
    • Rubtsova K, Rubtsov AV, Cancro MP, Marrack P. Age-Associated B Cells: A T-bet-Dependent effector with roles in protective and pathogenic immunity. J Immunol. 2015;195:1933–1937.
    • (2015) J Immunol , vol.195 , pp. 1933-1937
    • Rubtsova, K.1    Rubtsov, A.V.2    Cancro, M.P.3    Marrack, P.4
  • 52
    • 63749100579 scopus 로고    scopus 로고
    • A method for identification of HIV gp140 binding memory B cells in human blood
    • Scheid JF, Mouquet H, Feldhahn N, et al. A method for identification of HIV gp140 binding memory B cells in human blood. J Immunol Methods. 2009;343:65–67.
    • (2009) J Immunol Methods , vol.343 , pp. 65-67
    • Scheid, J.F.1    Mouquet, H.2    Feldhahn, N.3
  • 53
    • 84981158037 scopus 로고    scopus 로고
    • Maturational characteristics of HIV-specific antibodies in viremic individuals
    • Meffre E, Louie A, Bannock J, et al. Maturational characteristics of HIV-specific antibodies in viremic individuals. JCI Insight. 2016;1:e84610.
    • (2016) JCI Insight , vol.1
    • Meffre, E.1    Louie, A.2    Bannock, J.3
  • 54
    • 13544251387 scopus 로고    scopus 로고
    • Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response
    • Odendahl M, Mei H, Hoyer BF, et al. Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response. Blood. 2005;105:1614–1621.
    • (2005) Blood , vol.105 , pp. 1614-1621
    • Odendahl, M.1    Mei, H.2    Hoyer, B.F.3
  • 55
    • 84874182011 scopus 로고    scopus 로고
    • Origin and Function of Circulating Plasmablasts during Acute Viral Infections
    • Fink K. Origin and Function of Circulating Plasmablasts during Acute Viral Infections. Front Immunol. 2012;3:78.
    • (2012) Front Immunol , vol.3 , pp. 78
    • Fink, K.1
  • 56
    • 84884137500 scopus 로고    scopus 로고
    • Correlates of protection against influenza infection in humans–on the path to a universal vaccine?
    • Li CK, Rappuoli R, Xu XN. Correlates of protection against influenza infection in humans–on the path to a universal vaccine? Curr Opin Immunol. 2013;25:470–476.
    • (2013) Curr Opin Immunol , vol.25 , pp. 470-476
    • Li, C.K.1    Rappuoli, R.2    Xu, X.N.3
  • 57
    • 84954457040 scopus 로고    scopus 로고
    • c-Myb is required for plasma cell migration to bone marrow after immunization or infection
    • Good-Jacobson KL, O'Donnell K, Belz GT, Nutt SL, Tarlinton DM. c-Myb is required for plasma cell migration to bone marrow after immunization or infection. J Exp Med. 2015;212:1001–1009.
    • (2015) J Exp Med , vol.212 , pp. 1001-1009
    • Good-Jacobson, K.L.1    O'Donnell, K.2    Belz, G.T.3    Nutt, S.L.4    Tarlinton, D.M.5
  • 58
    • 84877329810 scopus 로고    scopus 로고
    • Characterization of plasmablasts in the blood of HIV-infected viremic individuals: evidence for nonspecific immune activation
    • Buckner CM, Moir S, Ho J, et al. Characterization of plasmablasts in the blood of HIV-infected viremic individuals: evidence for nonspecific immune activation. J Virol. 2013;87:5800–5811.
    • (2013) J Virol , vol.87 , pp. 5800-5811
    • Buckner, C.M.1    Moir, S.2    Ho, J.3
  • 59
    • 80055118908 scopus 로고    scopus 로고
    • Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated
    • Liao HX, Chen X, Munshaw S, et al. Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated. J Exp Med. 2011;208:2237–2249.
    • (2011) J Exp Med , vol.208 , pp. 2237-2249
    • Liao, H.X.1    Chen, X.2    Munshaw, S.3
  • 60
    • 63849146905 scopus 로고    scopus 로고
    • Blood-borne human plasma cells in steady state are derived from mucosal immune responses
    • Mei HE, Yoshida T, Sime W, et al. Blood-borne human plasma cells in steady state are derived from mucosal immune responses. Blood. 2009;113:2461–2469.
    • (2009) Blood , vol.113 , pp. 2461-2469
    • Mei, H.E.1    Yoshida, T.2    Sime, W.3
  • 61
    • 84865997747 scopus 로고    scopus 로고
    • Expansion of HIV-specific T follicular helper cells in chronic HIV infection
    • Lindqvist M, van Lunzen J, Soghoian DZ, et al. Expansion of HIV-specific T follicular helper cells in chronic HIV infection. J Clin Invest. 2012;122:3271–3280.
    • (2012) J Clin Invest , vol.122 , pp. 3271-3280
    • Lindqvist, M.1    van Lunzen, J.2    Soghoian, D.Z.3
  • 62
    • 84901804635 scopus 로고    scopus 로고
    • CXCR4/IgG-expressing plasma cells are associated with human gastrointestinal tissue inflammation
    • Buckner CM, Moir S, Kardava L, et al. CXCR4/IgG-expressing plasma cells are associated with human gastrointestinal tissue inflammation. J Allergy Clin Immunol. 2014;133(1676–1685):e1675.
    • (2014) J Allergy Clin Immunol , vol.133 , Issue.1676-1685
    • Buckner, C.M.1    Moir, S.2    Kardava, L.3
  • 63
    • 1642393388 scopus 로고    scopus 로고
    • Intestinal B cell hyperactivity in AIDS is controlled by highly active antiretroviral therapy
    • Nilssen DE, Oktedalen O, Brandtzaeg P. Intestinal B cell hyperactivity in AIDS is controlled by highly active antiretroviral therapy. Gut. 2004;53:487–493.
    • (2004) Gut , vol.53 , pp. 487-493
    • Nilssen, D.E.1    Oktedalen, O.2    Brandtzaeg, P.3
  • 64
    • 14244257818 scopus 로고    scopus 로고
    • Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization
    • Blink EJ, Light A, Kallies A, Nutt SL, Hodgkin PD, Tarlinton DM. Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization. J Exp Med. 2005;201:545–554.
    • (2005) J Exp Med , vol.201 , pp. 545-554
    • Blink, E.J.1    Light, A.2    Kallies, A.3    Nutt, S.L.4    Hodgkin, P.D.5    Tarlinton, D.M.6
  • 65
    • 81355127378 scopus 로고    scopus 로고
    • Staying alive: regulation of plasma cell survival
    • Tangye SG. Staying alive: regulation of plasma cell survival. Trends Immunol. 2011;32:595–602.
    • (2011) Trends Immunol , vol.32 , pp. 595-602
    • Tangye, S.G.1
  • 66
    • 84959212384 scopus 로고    scopus 로고
    • Role of Flow Cytometry in the Diagnosis and Prognosis of Plasma Cell Myeloma
    • Olteanu H. Role of Flow Cytometry in the Diagnosis and Prognosis of Plasma Cell Myeloma. Surg Pathol Clin. 2016;9:101–116.
    • (2016) Surg Pathol Clin , vol.9 , pp. 101-116
    • Olteanu, H.1
  • 67
    • 84931424223 scopus 로고    scopus 로고
    • Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus
    • Tipton CM, Fucile CF, Darce J, et al. Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus. Nat Immunol. 2015;16:755–765.
    • (2015) Nat Immunol , vol.16 , pp. 755-765
    • Tipton, C.M.1    Fucile, C.F.2    Darce, J.3
  • 68
    • 84937714861 scopus 로고    scopus 로고
    • Long-lived plasma cells are contained within the CD19(-)CD38(hi)CD138(+) subset in human bone marrow
    • Halliley JL, Tipton CM, Liesveld J, et al. Long-lived plasma cells are contained within the CD19(-)CD38(hi)CD138(+) subset in human bone marrow. Immunity. 2015;43:132–145.
    • (2015) Immunity , vol.43 , pp. 132-145
    • Halliley, J.L.1    Tipton, C.M.2    Liesveld, J.3
  • 69
    • 84924559557 scopus 로고    scopus 로고
    • Bone Marrow Plasma cells Are a Primary Source of Serum HIV-1-Specific Antibodies in Chronically Infected Individuals
    • Montezuma-Rusca JM, Moir S, Kardava L, et al. Bone Marrow Plasma cells Are a Primary Source of Serum HIV-1-Specific Antibodies in Chronically Infected Individuals. J Immunol. 2015;194:2561–2568.
    • (2015) J Immunol , vol.194 , pp. 2561-2568
    • Montezuma-Rusca, J.M.1    Moir, S.2    Kardava, L.3
  • 70
    • 0024339394 scopus 로고
    • Lymphadenopathy in HIV infection: histological classification and staging
    • Ost A, Baroni CD, Biberfeld P, et al. Lymphadenopathy in HIV infection: histological classification and staging. APMIS Suppl. 1989;8:7–15.
    • (1989) APMIS Suppl , vol.8 , pp. 7-15
    • Ost, A.1    Baroni, C.D.2    Biberfeld, P.3
  • 71
    • 0023203128 scopus 로고
    • Stages in LAV/HTLV-III lymphadenitis. I. Histological and immunohistological classification
    • Pallesen G, Gerstoft J, Mathiesen L. Stages in LAV/HTLV-III lymphadenitis. I. Histological and immunohistological classification. Scand J Immunol. 1987;25:83–91.
    • (1987) Scand J Immunol , vol.25 , pp. 83-91
    • Pallesen, G.1    Gerstoft, J.2    Mathiesen, L.3
  • 72
    • 84950153720 scopus 로고    scopus 로고
    • Age-associated B cells: key mediators of both protective and autoreactive humoral responses
    • Naradikian MS, Hao Y, Cancro MP. Age-associated B cells: key mediators of both protective and autoreactive humoral responses. Immunol Rev. 2016;269:118–129.
    • (2016) Immunol Rev , vol.269 , pp. 118-129
    • Naradikian, M.S.1    Hao, Y.2    Cancro, M.P.3
  • 73
    • 1842840003 scopus 로고    scopus 로고
    • Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system
    • Crotty S, Aubert RD, Glidewell J, Ahmed R. Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system. J Immunol Methods. 2004;286:111–122.
    • (2004) J Immunol Methods , vol.286 , pp. 111-122
    • Crotty, S.1    Aubert, R.D.2    Glidewell, J.3    Ahmed, R.4
  • 74
    • 84880967962 scopus 로고    scopus 로고
    • A functional BCR in human IgA and IgM plasma cells
    • Pinto D, Montani E, Bolli M, et al. A functional BCR in human IgA and IgM plasma cells. Blood. 2013;121:4110–4114.
    • (2013) Blood , vol.121 , pp. 4110-4114
    • Pinto, D.1    Montani, E.2    Bolli, M.3
  • 75
    • 0029743737 scopus 로고    scopus 로고
    • Phenotypic analysis of antigen-specific T lymphocytes
    • Altman JD, Moss PA, Goulder PJ, et al. Phenotypic analysis of antigen-specific T lymphocytes. Science. 1996;274:94–96.
    • (1996) Science , vol.274 , pp. 94-96
    • Altman, J.D.1    Moss, P.A.2    Goulder, P.J.3
  • 76
    • 84866495323 scopus 로고    scopus 로고
    • Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies
    • Kwong PD, Mascola JR. Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies. Immunity. 2012;37:412–425.
    • (2012) Immunity , vol.37 , pp. 412-425
    • Kwong, P.D.1    Mascola, J.R.2
  • 77
    • 84949035265 scopus 로고    scopus 로고
    • HIV-specific B cell response in patients with broadly neutralizing serum activity
    • Scheid JF. HIV-specific B cell response in patients with broadly neutralizing serum activity. Science. 2015;350:1175.
    • (2015) Science , vol.350 , pp. 1175
    • Scheid, J.F.1
  • 78
    • 82955201800 scopus 로고    scopus 로고
    • Prospects for an HIV vaccine: leading B cells down the right path
    • Moir S, Malaspina A, Fauci AS. Prospects for an HIV vaccine: leading B cells down the right path. Nat Struct Mol Biol. 2011;18:1317–1321.
    • (2011) Nat Struct Mol Biol , vol.18 , pp. 1317-1321
    • Moir, S.1    Malaspina, A.2    Fauci, A.S.3
  • 79
    • 70349249520 scopus 로고    scopus 로고
    • Selective expansion of HIV-1 envelope glycoprotein-specific B cell subsets recognizing distinct structural elements following immunization
    • Dosenovic P, Chakrabarti B, Soldemo M, et al. Selective expansion of HIV-1 envelope glycoprotein-specific B cell subsets recognizing distinct structural elements following immunization. J Immunol. 2009;183:3373–3382.
    • (2009) J Immunol , vol.183 , pp. 3373-3382
    • Dosenovic, P.1    Chakrabarti, B.2    Soldemo, M.3
  • 80
    • 80053584837 scopus 로고    scopus 로고
    • Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting
    • Morris L, Chen X, Alam M, et al. Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting. PLoS ONE. 2011;6:e23532.
    • (2011) PLoS ONE , vol.6
    • Morris, L.1    Chen, X.2    Alam, M.3
  • 81
    • 84936803233 scopus 로고    scopus 로고
    • H5N1 Vaccine-Elicited Memory B Cells Are Genetically Constrained by the IGHV Locus in the Recognition of a Neutralizing Epitope in the Hemagglutinin Stem
    • Wheatley AK, Whittle JR, Lingwood D, et al. H5N1 Vaccine-Elicited Memory B Cells Are Genetically Constrained by the IGHV Locus in the Recognition of a Neutralizing Epitope in the Hemagglutinin Stem. J Immunol. 2015;195:602–610.
    • (2015) J Immunol , vol.195 , pp. 602-610
    • Wheatley, A.K.1    Whittle, J.R.2    Lingwood, D.3
  • 82
    • 79960546363 scopus 로고    scopus 로고
    • Ex vivo characterization and isolation of rare memory B cells with antigen tetramers
    • Franz B, May KF Jr, Dranoff G, Wucherpfennig K. Ex vivo characterization and isolation of rare memory B cells with antigen tetramers. Blood. 2011;118:348–357.
    • (2011) Blood , vol.118 , pp. 348-357
    • Franz, B.1    May, K.F.2    Dranoff, G.3    Wucherpfennig, K.4
  • 83
    • 84896917279 scopus 로고    scopus 로고
    • Flow cytometry reveals that H5N1 vaccination elicits cross-reactive stem-directed antibodies from multiple Ig heavy-chain lineages
    • Whittle JR, Wheatley AK, Wu L, et al. Flow cytometry reveals that H5N1 vaccination elicits cross-reactive stem-directed antibodies from multiple Ig heavy-chain lineages. J Virol. 2014;88:4047–4057.
    • (2014) J Virol , vol.88 , pp. 4047-4057
    • Whittle, J.R.1    Wheatley, A.K.2    Wu, L.3
  • 84
    • 84874572370 scopus 로고    scopus 로고
    • Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies
    • Muellenbeck MF, Ueberheide B, Amulic B, et al. Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies. J Exp Med. 2013;210:389–399.
    • (2013) J Exp Med , vol.210 , pp. 389-399
    • Muellenbeck, M.F.1    Ueberheide, B.2    Amulic, B.3
  • 85
    • 84964474595 scopus 로고    scopus 로고
    • Rapid isolation of dengue-neutralizing antibodies from single cell-sorted human antigen-specific memory B-cell cultures
    • Cox KS, Tang A, Chen Z, et al. Rapid isolation of dengue-neutralizing antibodies from single cell-sorted human antigen-specific memory B-cell cultures. MAbs. 2016;8:129–140.
    • (2016) MAbs , vol.8 , pp. 129-140
    • Cox, K.S.1    Tang, A.2    Chen, Z.3
  • 86
    • 49149093819 scopus 로고    scopus 로고
    • Immunodominance of the VH1-46 antibody gene segment in the primary repertoire of human rotavirus-specific B cells is reduced in the memory compartment through somatic mutation of nondominant clones
    • Tian C, Luskin GK, Dischert KM, Higginbotham JN, Shepherd BE, Crowe JE Jr. Immunodominance of the VH1-46 antibody gene segment in the primary repertoire of human rotavirus-specific B cells is reduced in the memory compartment through somatic mutation of nondominant clones. J Immunol. 2008;180:3279–3288.
    • (2008) J Immunol , vol.180 , pp. 3279-3288
    • Tian, C.1    Luskin, G.K.2    Dischert, K.M.3    Higginbotham, J.N.4    Shepherd, B.E.5    Crowe, J.E.6
  • 87
    • 84908329318 scopus 로고    scopus 로고
    • Characteristics of memory B cells elicited by a highly efficacious HPV vaccine in subjects with no pre-existing immunity
    • Scherer EM, Smith RA, Simonich CA, Niyonzima N, Carter JJ, Galloway DA. Characteristics of memory B cells elicited by a highly efficacious HPV vaccine in subjects with no pre-existing immunity. PLoS Pathog. 2014;10:e1004461.
    • (2014) PLoS Pathog , vol.10
    • Scherer, E.M.1    Smith, R.A.2    Simonich, C.A.3    Niyonzima, N.4    Carter, J.J.5    Galloway, D.A.6
  • 88
    • 84869077778 scopus 로고    scopus 로고
    • HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins
    • Li Y, O'Dell S, Wilson R, et al. HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins. J Virol. 2012;86:11231–11241.
    • (2012) J Virol , vol.86 , pp. 11231-11241
    • Li, Y.1    O'Dell, S.2    Wilson, R.3
  • 89
    • 84863769888 scopus 로고    scopus 로고
    • The development of CD4 binding site antibodies during HIV-1 infection
    • Lynch RM, Tran L, Louder MK, et al. The development of CD4 binding site antibodies during HIV-1 infection. J Virol. 2012;86:7588–7595.
    • (2012) J Virol , vol.86 , pp. 7588-7595
    • Lynch, R.M.1    Tran, L.2    Louder, M.K.3
  • 90
    • 84873098187 scopus 로고    scopus 로고
    • A universal nanoparticle cell secretion capture assay
    • Fitzgerald W, Grivel JC. A universal nanoparticle cell secretion capture assay. Cytometry A. 2013;83:205–211.
    • (2013) Cytometry A , vol.83 , pp. 205-211
    • Fitzgerald, W.1    Grivel, J.C.2
  • 91
    • 84930948323 scopus 로고    scopus 로고
    • New approaches to HIV vaccine development
    • Haynes BF. New approaches to HIV vaccine development. Curr Opin Immunol. 2015;35:39–47.
    • (2015) Curr Opin Immunol , vol.35 , pp. 39-47
    • Haynes, B.F.1
  • 92
    • 84917705974 scopus 로고    scopus 로고
    • Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex
    • Sok D, van Gils MJ, Pauthner M, et al. Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex. Proc Natl Acad Sci U S A. 2014;111:17624–17629.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 17624-17629
    • Sok, D.1    van Gils, M.J.2    Pauthner, M.3
  • 93
    • 80052925616 scopus 로고    scopus 로고
    • Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding
    • Scheid JF, Mouquet H, Ueberheide B, et al. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science. 2011;333:1633–1637.
    • (2011) Science , vol.333 , pp. 1633-1637
    • Scheid, J.F.1    Mouquet, H.2    Ueberheide, B.3
  • 94
    • 80052942203 scopus 로고    scopus 로고
    • Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing
    • Wu X, Zhou T, Zhu J, et al. Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science. 2011;333:1593–1602.
    • (2011) Science , vol.333 , pp. 1593-1602
    • Wu, X.1    Zhou, T.2    Zhu, J.3
  • 95
    • 84863915210 scopus 로고    scopus 로고
    • High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site
    • Sundling C, Li Y, Huynh N, et al. High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site. Sci Transl Med. 2012;4:142ra196.
    • (2012) Sci Transl Med , vol.4 , pp. 142ra196
    • Sundling, C.1    Li, Y.2    Huynh, N.3
  • 96
    • 0024404415 scopus 로고
    • HIV-1-specific B cell activation. A major constituent of spontaneous B cell activation during HIV-1 infection
    • Amadori A, Zamarchi R, Ciminale V, et al. HIV-1-specific B cell activation. A major constituent of spontaneous B cell activation during HIV-1 infection. J Immunol. 1989;143:2146–2152.
    • (1989) J Immunol , vol.143 , pp. 2146-2152
    • Amadori, A.1    Zamarchi, R.2    Ciminale, V.3
  • 97
    • 73949138822 scopus 로고    scopus 로고
    • Loss of HIV-specific memory B-cells as a potential mechanism for the dysfunction of the humoral immune response against HIV
    • Bussmann BM, Reiche S, Bieniek B, Krznaric I, Ackermann F, Jassoy C. Loss of HIV-specific memory B-cells as a potential mechanism for the dysfunction of the humoral immune response against HIV. Virology. 2010;397:7–13.
    • (2010) Virology , vol.397 , pp. 7-13
    • Bussmann, B.M.1    Reiche, S.2    Bieniek, B.3    Krznaric, I.4    Ackermann, F.5    Jassoy, C.6
  • 98
    • 0742287274 scopus 로고    scopus 로고
    • Detection of peripheral HIV-1-specific memory B cells in patients untreated or receiving highly active antiretroviral therapy
    • Fondere JM, Huguet MF, Yssel H, et al. Detection of peripheral HIV-1-specific memory B cells in patients untreated or receiving highly active antiretroviral therapy. AIDS. 2003;17:2323–2330.
    • (2003) AIDS , vol.17 , pp. 2323-2330
    • Fondere, J.M.1    Huguet, M.F.2    Yssel, H.3
  • 99
    • 77649318846 scopus 로고    scopus 로고
    • Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals
    • Corti D, Langedijk JP, Hinz A, et al. Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals. PLoS ONE. 2010;5:e8805.
    • (2010) PLoS ONE , vol.5
    • Corti, D.1    Langedijk, J.P.2    Hinz, A.3
  • 100
    • 80053132436 scopus 로고    scopus 로고
    • Broad neutralization coverage of HIV by multiple highly potent antibodies
    • Walker LM, Huber M, Doores KJ, et al. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature. 2011;477:466–470.
    • (2011) Nature , vol.477 , pp. 466-470
    • Walker, L.M.1    Huber, M.2    Doores, K.J.3
  • 101
    • 70349887757 scopus 로고    scopus 로고
    • Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
    • Walker LM, Phogat SK, Chan-Hui PY, et al. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science. 2009;326:285–289.
    • (2009) Science , vol.326 , pp. 285-289
    • Walker, L.M.1    Phogat, S.K.2    Chan-Hui, P.Y.3
  • 102
    • 84899991983 scopus 로고    scopus 로고
    • Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
    • Doria-Rose NA, Schramm CA, Gorman J, et al. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature. 2014;509:55–62.
    • (2014) Nature , vol.509 , pp. 55-62
    • Doria-Rose, N.A.1    Schramm, C.A.2    Gorman, J.3
  • 103
    • 84866493348 scopus 로고    scopus 로고
    • Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
    • Huang J, Ofek G, Laub L, et al. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature. 2012;491:406–412.
    • (2012) Nature , vol.491 , pp. 406-412
    • Huang, J.1    Ofek, G.2    Laub, L.3
  • 104
    • 84921607768 scopus 로고    scopus 로고
    • Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface
    • Huang J, Kang BH, Pancera M, et al. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface. Nature. 2014;515:138–142.
    • (2014) Nature , vol.515 , pp. 138-142
    • Huang, J.1    Kang, B.H.2    Pancera, M.3
  • 105
    • 84884991510 scopus 로고    scopus 로고
    • Isolation of human monoclonal antibodies from peripheral blood B cells
    • Huang J, Doria-Rose NA, Longo NS, et al. Isolation of human monoclonal antibodies from peripheral blood B cells. Nat Protoc. 2013;8:1907–1915.
    • (2013) Nat Protoc , vol.8 , pp. 1907-1915
    • Huang, J.1    Doria-Rose, N.A.2    Longo, N.S.3
  • 106
    • 84958825022 scopus 로고    scopus 로고
    • Efficient methods to isolate human monoclonal antibodies from memory B cells and plasma cells
    • Corti D, Lanzavecchia A. Efficient methods to isolate human monoclonal antibodies from memory B cells and plasma cells. Microbiol Spectr. 2014;2:AID-0018-2014.
    • (2014) Microbiol Spectr , vol.2
    • Corti, D.1    Lanzavecchia, A.2
  • 107
    • 79952282195 scopus 로고    scopus 로고
    • Different B cell populations mediate early and late memory during an endogenous immune response
    • Pape KA, Taylor JJ, Maul RW, Gearhart PJ, Jenkins MK. Different B cell populations mediate early and late memory during an endogenous immune response. Science. 2011;331:1203–1207.
    • (2011) Science , vol.331 , pp. 1203-1207
    • Pape, K.A.1    Taylor, J.J.2    Maul, R.W.3    Gearhart, P.J.4    Jenkins, M.K.5
  • 108
    • 77953643545 scopus 로고    scopus 로고
    • Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy
    • Cagigi A, Nilsson A, Pensieroso S, Chiodi F. Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy. Lancet Infect Dis. 2010;10:499–503.
    • (2010) Lancet Infect Dis , vol.10 , pp. 499-503
    • Cagigi, A.1    Nilsson, A.2    Pensieroso, S.3    Chiodi, F.4
  • 109
    • 0041828179 scopus 로고    scopus 로고
    • Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection
    • Fiebig EW, Wright DJ, Rawal BD, et al. Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection. AIDS. 2003;17:1871–1879.
    • (2003) AIDS , vol.17 , pp. 1871-1879
    • Fiebig, E.W.1    Wright, D.J.2    Rawal, B.D.3
  • 110
    • 57349127300 scopus 로고    scopus 로고
    • Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia
    • Tomaras GD, Yates NL, Liu P, et al. Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia. J Virol. 2008;82:12449–12463.
    • (2008) J Virol , vol.82 , pp. 12449-12463
    • Tomaras, G.D.1    Yates, N.L.2    Liu, P.3
  • 111
    • 81155159842 scopus 로고    scopus 로고
    • Multiple HIV-1-specific IgG3 responses decline during acute HIV-1: implications for detection of incident HIV infection
    • Yates NL, Lucas JT, Nolen TL, et al. Multiple HIV-1-specific IgG3 responses decline during acute HIV-1: implications for detection of incident HIV infection. AIDS. 2011;25:2089–2097.
    • (2011) AIDS , vol.25 , pp. 2089-2097
    • Yates, N.L.1    Lucas, J.T.2    Nolen, T.L.3
  • 112
    • 84942930366 scopus 로고    scopus 로고
    • Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centers
    • Budeus B, Schweigle de Reynoso S, Przekopowitz M, Hoffmann D, Seifert M, Kuppers R. Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centers. Proc Natl Acad Sci USA. 2015;112:E5281–E5289.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. E5281-E5289
    • Budeus, B.1    Schweigle de Reynoso, S.2    Przekopowitz, M.3    Hoffmann, D.4    Seifert, M.5    Kuppers, R.6
  • 113
    • 29744464695 scopus 로고    scopus 로고
    • ABCB1 transporter discriminates human resting naive B cells from cycling transitional and memory B cells
    • Wirths S, Lanzavecchia A. ABCB1 transporter discriminates human resting naive B cells from cycling transitional and memory B cells. Eur J Immunol. 2005;35:3433–3441.
    • (2005) Eur J Immunol , vol.35 , pp. 3433-3441
    • Wirths, S.1    Lanzavecchia, A.2
  • 114
    • 77953681422 scopus 로고    scopus 로고
    • Stability of IgG isotypes in serum
    • Correia IR. Stability of IgG isotypes in serum. MAbs. 2010;2:221–232.
    • (2010) MAbs , vol.2 , pp. 221-232
    • Correia, I.R.1
  • 115
    • 84899087118 scopus 로고    scopus 로고
    • Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination
    • Yates NL, Liao HX, Fong Y, et al. Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination. Sci Transl Med. 2014;6:228ra239.
    • (2014) Sci Transl Med , vol.6 , pp. 228ra239
    • Yates, N.L.1    Liao, H.X.2    Fong, Y.3
  • 116
    • 84946223348 scopus 로고    scopus 로고
    • Dissecting polyclonal vaccine-induced humoral immunity against HIV using systems serology
    • Chung AW, Kumar MP, Arnold KB, et al. Dissecting polyclonal vaccine-induced humoral immunity against HIV using systems serology. Cell. 2015;163:988–998.
    • (2015) Cell , vol.163 , pp. 988-998
    • Chung, A.W.1    Kumar, M.P.2    Arnold, K.B.3
  • 117
    • 84919949772 scopus 로고    scopus 로고
    • HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteria
    • Trama AM, Moody MA, Alam SM, et al. HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteria. Cell Host Microbe. 2014;16:215–226.
    • (2014) Cell Host Microbe , vol.16 , pp. 215-226
    • Trama, A.M.1    Moody, M.A.2    Alam, S.M.3
  • 118
    • 84940192994 scopus 로고    scopus 로고
    • Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies
    • Williams WB, Liao HX, Moody MA, et al. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies. Science. 2015;349:aab1253.
    • (2015) Science , vol.349 , pp. aab1253
    • Williams, W.B.1    Liao, H.X.2    Moody, M.A.3
  • 119
    • 0028235930 scopus 로고
    • Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS
    • Muster T, Guinea R, Trkola A, et al. Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS. J Virol. 1994;68:4031–4034.
    • (1994) J Virol , vol.68 , pp. 4031-4034
    • Muster, T.1    Guinea, R.2    Trkola, A.3
  • 120
    • 0035701421 scopus 로고    scopus 로고
    • A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1
    • Stiegler G, Kunert R, Purtscher M, et al. A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1. AIDS Res Hum Retroviruses. 2001;17:1757–1765.
    • (2001) AIDS Res Hum Retroviruses , vol.17 , pp. 1757-1765
    • Stiegler, G.1    Kunert, R.2    Purtscher, M.3
  • 121
    • 84897051685 scopus 로고    scopus 로고
    • The imperfect control of self-reactive germinal center B cells
    • Brink R. The imperfect control of self-reactive germinal center B cells. Curr Opin Immunol. 2014;28:97–101.
    • (2014) Curr Opin Immunol , vol.28 , pp. 97-101
    • Brink, R.1
  • 123
    • 77957355961 scopus 로고    scopus 로고
    • Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
    • Mouquet H, Scheid JF, Zoller MJ, et al. Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation. Nature. 2010;467:591–595.
    • (2010) Nature , vol.467 , pp. 591-595
    • Mouquet, H.1    Scheid, J.F.2    Zoller, M.J.3
  • 124
    • 84919430580 scopus 로고    scopus 로고
    • Polyreactivity and autoreactivity among HIV-1 antibodies
    • Liu M, Yang G, Wiehe K, et al. Polyreactivity and autoreactivity among HIV-1 antibodies. J Virol. 2015;89:784–798.
    • (2015) J Virol , vol.89 , pp. 784-798
    • Liu, M.1    Yang, G.2    Wiehe, K.3
  • 125
    • 84929896699 scopus 로고    scopus 로고
    • Antibody responses to envelope glycoproteins in HIV-1 infection
    • Burton DR, Mascola JR. Antibody responses to envelope glycoproteins in HIV-1 infection. Nat Immunol. 2015;16:571–576.
    • (2015) Nat Immunol , vol.16 , pp. 571-576
    • Burton, D.R.1    Mascola, J.R.2
  • 126
    • 73949084963 scopus 로고    scopus 로고
    • Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables
    • Doria-Rose NA, Klein RM, Daniels MG, et al. Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables. J Virol. 2010;84:1631–1636.
    • (2010) J Virol , vol.84 , pp. 1631-1636
    • Doria-Rose, N.A.1    Klein, R.M.2    Daniels, M.G.3
  • 127
    • 70349298392 scopus 로고    scopus 로고
    • Breadth of neutralizing antibody response to human immunodeficiency virus type 1 is affected by factors early in infection but does not influence disease progression
    • Piantadosi A, Panteleeff D, Blish CA, et al. Breadth of neutralizing antibody response to human immunodeficiency virus type 1 is affected by factors early in infection but does not influence disease progression. J Virol. 2009;83:10269–10274.
    • (2009) J Virol , vol.83 , pp. 10269-10274
    • Piantadosi, A.1    Panteleeff, D.2    Blish, C.A.3
  • 128
    • 79955389756 scopus 로고    scopus 로고
    • + T cell decline and high viral load during acute infection
    • + T cell decline and high viral load during acute infection. J Virol. 2011;85:4828–4840.
    • (2011) J Virol , vol.85 , pp. 4828-4840
    • Gray, E.S.1    Madiga, M.C.2    Hermanus, T.3
  • 129
    • 84956714697 scopus 로고    scopus 로고
    • Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort
    • Landais E, Huang X, Havenar-Daughton C, et al. Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort. PLoS Pathog. 2016;12:e1005369.
    • (2016) PLoS Pathog , vol.12
    • Landais, E.1    Huang, X.2    Havenar-Daughton, C.3
  • 131
    • 80055104586 scopus 로고    scopus 로고
    • Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals
    • Tomaras GD, Binley JM, Gray ES, et al. Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals. J Virol. 2011;85:11502–11519.
    • (2011) J Virol , vol.85 , pp. 11502-11519
    • Tomaras, G.D.1    Binley, J.M.2    Gray, E.S.3
  • 132
    • 63849131879 scopus 로고    scopus 로고
    • Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
    • Scheid JF, Mouquet H, Feldhahn N, et al. Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals. Nature. 2009;458:636–640.
    • (2009) Nature , vol.458 , pp. 636-640
    • Scheid, J.F.1    Mouquet, H.2    Feldhahn, N.3
  • 133
    • 80052531336 scopus 로고    scopus 로고
    • Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses
    • Mouquet H, Klein F, Scheid JF, et al. Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. PLoS ONE. 2011;6:e24078.
    • (2011) PLoS ONE , vol.6
    • Mouquet, H.1    Klein, F.2    Scheid, J.F.3
  • 134
    • 84937761089 scopus 로고    scopus 로고
    • Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection
    • Wu X, Zhang Z, Schramm CA, et al. Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell. 2015;161:470–485.
    • (2015) Cell , vol.161 , pp. 470-485
    • Wu, X.1    Zhang, Z.2    Schramm, C.A.3
  • 135
    • 84876797103 scopus 로고    scopus 로고
    • Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
    • Liao HX, Lynch R, Zhou T, et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature. 2013;496:469–476.
    • (2013) Nature , vol.496 , pp. 469-476
    • Liao, H.X.1    Lynch, R.2    Zhou, T.3
  • 136
    • 84946576244 scopus 로고    scopus 로고
    • Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies
    • Bhiman JN, Anthony C, Doria-Rose NA, et al. Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies. Nat Med. 2015;21:1332–1336.
    • (2015) Nat Med , vol.21 , pp. 1332-1336
    • Bhiman, J.N.1    Anthony, C.2    Doria-Rose, N.A.3
  • 137
    • 79952579682 scopus 로고    scopus 로고
    • Potent and broad neutralization of HIV-1 subtype C by plasma antibodies targeting a quaternary epitope including residues in the V2 loop
    • Moore PL, Gray ES, Sheward D, et al. Potent and broad neutralization of HIV-1 subtype C by plasma antibodies targeting a quaternary epitope including residues in the V2 loop. J Virol. 2011;85:3128–3141.
    • (2011) J Virol , vol.85 , pp. 3128-3141
    • Moore, P.L.1    Gray, E.S.2    Sheward, D.3
  • 138
    • 84966341056 scopus 로고    scopus 로고
    • HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1
    • Schoofs T, Klein F, Braunschweig M, et al. HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1. Science. 2016;352:997–1001.
    • (2016) Science , vol.352 , pp. 997-1001
    • Schoofs, T.1    Klein, F.2    Braunschweig, M.3
  • 139
    • 77954920017 scopus 로고    scopus 로고
    • Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
    • Wu X, Yang ZY, Li Y, et al. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science. 2010;329:856–861.
    • (2010) Science , vol.329 , pp. 856-861
    • Wu, X.1    Yang, Z.Y.2    Li, Y.3
  • 140
    • 84930418589 scopus 로고    scopus 로고
    • Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors
    • Zhou T, Lynch RM, Chen L, et al. Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell. 2015;161:1280–1292.
    • (2015) Cell , vol.161 , pp. 1280-1292
    • Zhou, T.1    Lynch, R.M.2    Chen, L.3
  • 141
    • 77749306129 scopus 로고    scopus 로고
    • Cross-reactive neutralizing humoral immunity does not protect from HIV type 1 disease progression
    • Euler Z, van Gils MJ, Bunnik EM, et al. Cross-reactive neutralizing humoral immunity does not protect from HIV type 1 disease progression. J Infect Dis. 2010;201:1045–1053.
    • (2010) J Infect Dis , vol.201 , pp. 1045-1053
    • Euler, Z.1    van Gils, M.J.2    Bunnik, E.M.3
  • 142
    • 84925844719 scopus 로고    scopus 로고
    • Virological features associated with the development of broadly neutralizing antibodies to HIV-1
    • Moore PL, Williamson C, Morris L. Virological features associated with the development of broadly neutralizing antibodies to HIV-1. Trends Microbiol. 2015;23:204–211.
    • (2015) Trends Microbiol , vol.23 , pp. 204-211
    • Moore, P.L.1    Williamson, C.2    Morris, L.3
  • 144
    • 40049100634 scopus 로고    scopus 로고
    • Normalization of B cell counts and subpopulations after antiretroviral therapy in chronic HIV disease
    • Moir S, Malaspina A, Ho J, et al. Normalization of B cell counts and subpopulations after antiretroviral therapy in chronic HIV disease. J Infect Dis. 2008;197:572–579.
    • (2008) J Infect Dis , vol.197 , pp. 572-579
    • Moir, S.1    Malaspina, A.2    Ho, J.3
  • 145
    • 66149114013 scopus 로고    scopus 로고
    • Timing of HAART defines the integrity of memory B cells and the longevity of humoral responses in HIV-1 vertically-infected children
    • Pensieroso S, Cagigi A, Palma P, et al. Timing of HAART defines the integrity of memory B cells and the longevity of humoral responses in HIV-1 vertically-infected children. Proc Natl Acad Sci U S A. 2009;106:7939–7944.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 7939-7944
    • Pensieroso, S.1    Cagigi, A.2    Palma, P.3
  • 146
    • 84864483910 scopus 로고    scopus 로고
    • The impact of B-cell perturbations on pneumococcal conjugate vaccine response in HIV-infected adults
    • Johannesson TG, Sogaard OS, Tolstrup M, et al. The impact of B-cell perturbations on pneumococcal conjugate vaccine response in HIV-infected adults. PLoS ONE. 2012;7:e42307.
    • (2012) PLoS ONE , vol.7
    • Johannesson, T.G.1    Sogaard, O.S.2    Tolstrup, M.3
  • 147
    • 78650969171 scopus 로고    scopus 로고
    • High expression levels of B lymphocyte stimulator (BLyS) by dendritic cells correlate with HIV-related B-cell disease progression in humans
    • Fontaine J, Chagnon-Choquet J, Valcke HS, et al. High expression levels of B lymphocyte stimulator (BLyS) by dendritic cells correlate with HIV-related B-cell disease progression in humans. Blood. 2011;117:145–155.
    • (2011) Blood , vol.117 , pp. 145-155
    • Fontaine, J.1    Chagnon-Choquet, J.2    Valcke, H.S.3
  • 148
    • 0037032065 scopus 로고    scopus 로고
    • Dynamics of spontaneous HIV-1 specific and non-specific B-cell responses in patients receiving antiretroviral therapy
    • Fournier AM, Baillat V, Alix-Panabieres C, et al. Dynamics of spontaneous HIV-1 specific and non-specific B-cell responses in patients receiving antiretroviral therapy. AIDS. 2002;16:1755–1760.
    • (2002) AIDS , vol.16 , pp. 1755-1760
    • Fournier, A.M.1    Baillat, V.2    Alix-Panabieres, C.3
  • 149
    • 77955431162 scopus 로고    scopus 로고
    • The impact of active HIV-1 replication on the physiological age-related decline of immature-transitional B-cells in HIV-1 infected children
    • Cagigi A, Palma P, Nilsson A, et al. The impact of active HIV-1 replication on the physiological age-related decline of immature-transitional B-cells in HIV-1 infected children. AIDS. 2010;24:2075–2080.
    • (2010) AIDS , vol.24 , pp. 2075-2080
    • Cagigi, A.1    Palma, P.2    Nilsson, A.3
  • 150
    • 70349916366 scopus 로고    scopus 로고
    • Memory B cell function in HIV-infected children-decreased memory B cells despite ART
    • Ghosh S, Feyen O, Jebran AF, et al. Memory B cell function in HIV-infected children-decreased memory B cells despite ART. Pediatr Res. 2009;66:185–190.
    • (2009) Pediatr Res , vol.66 , pp. 185-190
    • Ghosh, S.1    Feyen, O.2    Jebran, A.F.3
  • 151
    • 84937719532 scopus 로고    scopus 로고
    • Control of viremia enables acquisition of resting memory B cells with age and normalization of activated B cell phenotypes in HIV-infected children
    • Muema DM, Macharia GN, Hassan AS, et al. Control of viremia enables acquisition of resting memory B cells with age and normalization of activated B cell phenotypes in HIV-infected children. J Immunol. 2015;195:1082–1091.
    • (2015) J Immunol , vol.195 , pp. 1082-1091
    • Muema, D.M.1    Macharia, G.N.2    Hassan, A.S.3
  • 152
    • 77957377793 scopus 로고    scopus 로고
    • Characterising B cell numbers and memory B cells in HIV infected and uninfected Malawian adults
    • Longwe H, Gordon S, Malamba R, French N. Characterising B cell numbers and memory B cells in HIV infected and uninfected Malawian adults. BMC Infect Dis. 2010;10:280.
    • (2010) BMC Infect Dis , vol.10 , pp. 280
    • Longwe, H.1    Gordon, S.2    Malamba, R.3    French, N.4
  • 153
    • 27944503534 scopus 로고    scopus 로고
    • Primary HIV-1 infection sets the stage for important B lymphocyte dysfunctions
    • Titanji K, Chiodi F, Bellocco R, et al. Primary HIV-1 infection sets the stage for important B lymphocyte dysfunctions. AIDS. 2005;19:1947–1955.
    • (2005) AIDS , vol.19 , pp. 1947-1955
    • Titanji, K.1    Chiodi, F.2    Bellocco, R.3
  • 154
    • 84886303941 scopus 로고    scopus 로고
    • Evolution of broadly cross-reactive HIV-1-neutralizing activity: therapy-associated decline, positive association with detectable viremia, and partial restoration of B-cell subpopulations
    • Ferreira CB, Merino-Mansilla A, Llano A, et al. Evolution of broadly cross-reactive HIV-1-neutralizing activity: therapy-associated decline, positive association with detectable viremia, and partial restoration of B-cell subpopulations. J Virol. 2013;87:12227–12236.
    • (2013) J Virol , vol.87 , pp. 12227-12236
    • Ferreira, C.B.1    Merino-Mansilla, A.2    Llano, A.3
  • 156
    • 84886885848 scopus 로고    scopus 로고
    • Lack of B cell dysfunction is associated with functional, gp120-dominant antibody responses in breast milk of simian immunodeficiency virus-infected African green monkeys
    • Amos JD, Wilks AB, Fouda GG, et al. Lack of B cell dysfunction is associated with functional, gp120-dominant antibody responses in breast milk of simian immunodeficiency virus-infected African green monkeys. J Virol. 2013;87:11121–11134.
    • (2013) J Virol , vol.87 , pp. 11121-11134
    • Amos, J.D.1    Wilks, A.B.2    Fouda, G.G.3
  • 157
    • 84898605219 scopus 로고    scopus 로고
    • HIV-1 specific antibody titers and neutralization among chronically infected patients on long-term suppressive antiretroviral therapy (ART): a cross-sectional study
    • Gach JS, Achenbach CJ, Chromikova V, et al. HIV-1 specific antibody titers and neutralization among chronically infected patients on long-term suppressive antiretroviral therapy (ART): a cross-sectional study. PLoS ONE. 2014;9:e85371.
    • (2014) PLoS ONE , vol.9
    • Gach, J.S.1    Achenbach, C.J.2    Chromikova, V.3
  • 158
    • 84929866964 scopus 로고    scopus 로고
    • Success and failure of the cellular immune response against HIV-1
    • Migueles SA, Connors M. Success and failure of the cellular immune response against HIV-1. Nat Immunol. 2015;16:563–570.
    • (2015) Nat Immunol , vol.16 , pp. 563-570
    • Migueles, S.A.1    Connors, M.2
  • 159
    • 84879614980 scopus 로고    scopus 로고
    • Unravelling the mechanisms of durable control of HIV-1
    • Walker BD, Yu XG. Unravelling the mechanisms of durable control of HIV-1. Nat Rev Immunol. 2013;13:487–498.
    • (2013) Nat Rev Immunol , vol.13 , pp. 487-498
    • Walker, B.D.1    Yu, X.G.2
  • 160
    • 0031875614 scopus 로고    scopus 로고
    • HIV-1 antigen-specific and -nonspecific B cell responses are sensitive to combination antiretroviral therapy
    • Morris L, Binley JM, Clas BA, et al. HIV-1 antigen-specific and -nonspecific B cell responses are sensitive to combination antiretroviral therapy. J Exp Med. 1998;188:233–245.
    • (1998) J Exp Med , vol.188 , pp. 233-245
    • Morris, L.1    Binley, J.M.2    Clas, B.A.3
  • 161
    • 62649166814 scopus 로고    scopus 로고
    • Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection
    • Guan Y, Sajadi MM, Kamin-Lewis R, et al. Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection. Proc Natl Acad Sci U S A. 2009;106:3952–3957.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3952-3957
    • Guan, Y.1    Sajadi, M.M.2    Kamin-Lewis, R.3
  • 162
    • 84981167153 scopus 로고    scopus 로고
    • Maintenance of HIV-specific memory B-cell responses in elite controllers despite low viral burdens
    • Buckner CM, Kardava L, Zhang X, et al. Maintenance of HIV-specific memory B-cell responses in elite controllers despite low viral burdens. J Infect Dis. 2016;214:390–398.
    • (2016) J Infect Dis , vol.214 , pp. 390-398
    • Buckner, C.M.1    Kardava, L.2    Zhang, X.3
  • 163
    • 84957677798 scopus 로고    scopus 로고
    • Regulation of germinal center B-cell differentiation
    • Zhang Y, Garcia-Ibanez L, Toellner KM. Regulation of germinal center B-cell differentiation. Immunol Rev. 2016;270:8–19.
    • (2016) Immunol Rev , vol.270 , pp. 8-19
    • Zhang, Y.1    Garcia-Ibanez, L.2    Toellner, K.M.3
  • 164
    • 84865395104 scopus 로고    scopus 로고
    • CD4 T follicular helper cell dynamics during SIV infection
    • Petrovas C, Yamamoto T, Gerner MY, et al. CD4 T follicular helper cell dynamics during SIV infection. J Clin Invest. 2012;122:3281–3294.
    • (2012) J Clin Invest , vol.122 , pp. 3281-3294
    • Petrovas, C.1    Yamamoto, T.2    Gerner, M.Y.3
  • 165
    • 84859415408 scopus 로고    scopus 로고
    • Spatial alterations between CD4(+) T follicular helper, B, and CD8(+) T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape
    • Hong JJ, Amancha PK, Rogers K, Ansari AA, Villinger F. Spatial alterations between CD4(+) T follicular helper, B, and CD8(+) T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape. J Immunol. 2012;188:3247–3256.
    • (2012) J Immunol , vol.188 , pp. 3247-3256
    • Hong, J.J.1    Amancha, P.K.2    Rogers, K.3    Ansari, A.A.4    Villinger, F.5
  • 166
    • 84874519282 scopus 로고    scopus 로고
    • Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production
    • Perreau M, Savoye AL, De Crignis E, et al. Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production. J Exp Med. 2013;210:143–156.
    • (2013) J Exp Med , vol.210 , pp. 143-156
    • Perreau, M.1    Savoye, A.L.2    De Crignis, E.3
  • 167
    • 84906043406 scopus 로고    scopus 로고
    • The dysfunction of T follicular helper cells
    • Cubas R, Perreau M. The dysfunction of T follicular helper cells. Curr Opin HIV AIDS. 2014;9:485–491.
    • (2014) Curr Opin HIV AIDS , vol.9 , pp. 485-491
    • Cubas, R.1    Perreau, M.2
  • 168
    • 84906054665 scopus 로고    scopus 로고
    • B-cell exhaustion in HIV infection: the role of immune activation
    • Moir S, Fauci AS. B-cell exhaustion in HIV infection: the role of immune activation. Curr Opin HIV AIDS. 2014;9:472–477.
    • (2014) Curr Opin HIV AIDS , vol.9 , pp. 472-477
    • Moir, S.1    Fauci, A.S.2
  • 169
    • 84937837169 scopus 로고    scopus 로고
    • Molecular and cellular insights into T cell exhaustion
    • Wherry EJ, Kurachi M. Molecular and cellular insights into T cell exhaustion. Nat Rev Immunol. 2015;15:486–499.
    • (2015) Nat Rev Immunol , vol.15 , pp. 486-499
    • Wherry, E.J.1    Kurachi, M.2
  • 170
    • 84898545152 scopus 로고    scopus 로고
    • T follicular helper cells and HIV/SIV-specific antibody responses
    • Petrovas C, Koup RA. T follicular helper cells and HIV/SIV-specific antibody responses. Curr Opin HIV AIDS. 2014;9:235–241.
    • (2014) Curr Opin HIV AIDS , vol.9 , pp. 235-241
    • Petrovas, C.1    Koup, R.A.2
  • 171
    • 84908377312 scopus 로고    scopus 로고
    • + helper T cells and B cell activation predict the breadth of neutralizing antibody responses in chronic HIV-1 infection
    • + helper T cells and B cell activation predict the breadth of neutralizing antibody responses in chronic HIV-1 infection. J Virol. 2014;88:13310–13321.
    • (2014) J Virol , vol.88 , pp. 13310-13321
    • Cohen, K.1    Altfeld, M.2    Alter, G.3    Stamatatos, L.4
  • 172
    • 84893746319 scopus 로고    scopus 로고
    • Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection
    • Boswell KL, Paris R, Boritz E, et al. Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection. PLoS Pathog. 2014;10:e1003853.
    • (2014) PLoS Pathog , vol.10
    • Boswell, K.L.1    Paris, R.2    Boritz, E.3
  • 173
    • 84885962913 scopus 로고    scopus 로고
    • GagPol-specific CD4(+) T-cells increase the antibody response to Env by intrastructural help
    • Nabi G, Genannt Bonsmann MS, Tenbusch M, et al. GagPol-specific CD4(+) T-cells increase the antibody response to Env by intrastructural help. Retrovirology. 2013;10:117.
    • (2013) Retrovirology , vol.10 , pp. 117
    • Nabi, G.1    Genannt Bonsmann, M.S.2    Tenbusch, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.