Bone marrow plasma cells are a primary source of serum HIV-1-specific antibodies in chronically infected individuals

Journal of Immunology

Volumn 194, Issue 6, 2015, Pages 2561-2568

  Montezuma Rusca, Jairo M ^a   Moir, Susan ^a   Kardava, Lela ^a   Buckner, Clarisa M ^a   Louie, Aaron ^a   Kim, Leo J Y ^a,e   Santich, Brian H ^a,f   Wang, Wei ^a   Fankuchen, Olivia R ^a   Diaz, Gabriella ^b   Daub, Janine R ^a   Rosenzweig, Sergio D ^c   Chun, Tae Wook ^a   Li, Yuxing ^a,d,g   Braylan, Raul C ^c   Calvo, Katherine R ^c   Fauci, Anthony S ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e CASE WESTERN RESERVE UNIVERSITY   (United States)

^f Gerstner Sloan Kettering Graduate School of Biomedical Sciences   (United States)

^g UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; NEUTRALIZING ANTIBODY; VIRUS ENVELOPE PROTEIN;

ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; BONE MARROW BIOPSY; BONE MARROW PLASMA CELL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN TISSUE; HYPERGAMMAGLOBULINEMIA; MALE; MEMORY CELL; PLASMA CELL; PRE B LYMPHOCYTE; PRIORITY JOURNAL; YOUNG ADULT; BLOOD; BONE MARROW; BONE MARROW CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HOST PATHOGEN INTERACTION; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; LYMPHOCYTE COUNT; METABOLISM; PHYSIOLOGY; VIROLOGY;

ADULT; ANTIBODIES, NEUTRALIZING; B-LYMPHOCYTE SUBSETS; B-LYMPHOCYTES; BONE MARROW; BONE MARROW CELLS; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HIV ANTIBODIES; HIV INFECTIONS; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOLOGIC MEMORY; LYMPHOCYTE COUNT; MALE; PLASMA CELLS; PRECURSOR CELLS, B-LYMPHOID; YOUNG ADULT;

EID: 84924559557     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402424     Document Type: Article

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