Multiple HIV-1-specific IgG3 responses decline during acute HIV-1: Implications for detection of incident HIV infection

AIDS

Volumn 25, Issue 17, 2011, Pages 2089-2097

  Yates, Nicole L ^a,b   Lucas, Judith T ^a,b   Nolen, Tracy L ^c   Vandergrift, Nathan A ^a,b   Soderberg, Kelly A ^a,b   Seaton, Kelly E ^a,b   Denny, Thomas N ^a,b   Haynes, Barton F ^a,b   Cohen, Myron S ^d   Tomaras, Georgia D ^a,b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Surgery ^*  (United States)

^c RTI INTERNATIONAL   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

HIV 1 acute infection; HIV 1 incidence; Immunoglobulin G subclass

Indexed keywords

GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 140; GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G3 ANTIBODY; NEF PROTEIN; PROTEIN P55; PROTEIN P66; TRANSACTIVATOR PROTEIN;

ADOLESCENT; ADULT; ANTIGEN BINDING; ANTIGEN SPECIFICITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE RESPONSE; INCIDENCE; MALE; PRIORITY JOURNAL; VIRUS TRANSMISSION;

ADOLESCENT; ADULT; ALGORITHMS; ANTIBODY SPECIFICITY; ANTIGEN-ANTIBODY REACTIONS; BIOLOGICAL MARKERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HIV ANTIGENS; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; TIME FACTORS; VIRAL LOAD; YOUNG ADULT;

EID: 81155159842     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e32834b348e     Document Type: Article

References (31)

1. Levesque MC, Moody MA, Hwang KK, Marshall DJ, Whitesides JF, Amos JD, et al. Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection. PLoS Med 2009; 6:e1000107.
2. Tomaras GD, Yates NL, Liu P, Qin L, Fouda GG, Chavez LL, et al. Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma antigp41 antibodies with ineffective control of initial viremia. J Virol 2008; 82:12449-12463.
3. Cohen MS, Fidler S. HIVprevention 2010:where arewenowand where are we going?. Curr Opin HIV AIDS 2010; 5:265-268.
4. Parekh BS, Kennedy MS, Dobbs T, Pau CP, Byers R, Green T, et al. Quantitative detection of increasing HIV type 1 antibodies after seroconversion: a simple assay for detecting recent HIV infection and estimating incidence. AIDS ResHumRetrovir 2002; 18:295-307. (Pubitemid 34253148)
5. Suligoi B, Galli C, Massi M, Di Sora F, Sciandra M, Pezzotti P, et al. Precision and accuracy of a procedure for detecting recent human immunodeficiency virus infections by calculating the antibody avidity index by an automated immunoassaybased method. J Clin Microbiol 2002; 40:4015-4020. (Pubitemid 35285783)
6. Sakarovitch C, Rouet F, Murphy G, Minga AK, Alioum A, Dabis F, et al. Do tests devised to detect recent HIV-1 infection provide reliable estimates of incidence in Africa? J Acquir Immune Defic Syndr 2007; 45:115-122. (Pubitemid 46684451)
7. Pandori MW, Hackett J Jr, Louie B, Vallari A, Dowling T, Liska S, et al. Assessment of the ability of a fourth-generation immunoassay for human immunodeficiency virus (HIV) antibody and p24 antigen to detect both acute and recent HIV infections in a high-risk setting. J Clin Microbiol 2009; 47:2639-2642.
8. Karita E, Price M, Hunter E, Chomba E, Allen S, Fei L, et al. Investigating the utility of the HIV-1 BED capture enzyme immunoassay using cross-sectional and longitudinal seroconverter specimens from Africa. AIDS 2007; 21:403-408.
9. Marinda ET, Hargrove J, Preiser W, Slabbert H, van Zyl G, Levin J, et al. Significantly diminished long-term specificity of the BED capture enzyme immunoassay among patients with HIV-1 with very low CD4 counts and those on antiretroviral therapy. J Acquir Immune Defic Syndr 2010; 53:496-499.
10. Hladik W, Olara D, Mermin J, Moore D, Were W, Alexander L, et al. Effect of CD4(R) T cell count and antiretroviral treatment on two serological HIV incidence assays. AIDS Res Hum Retroviruses 2011; [Epub ahead of print] doi:10.1089/aid.2010.0347.
11. Broliden PA, Morfeldt-Mansson L, Rosen J, Jondal M, Wahren B. Fine specificity of IgG subclass response to group antigens in HIV-1-infected patients. Clin Exp Immunol 1989; 76:216-221. (Pubitemid 19150391)
12. Tomaras GD, Haynes BF. HIV-1-specific antibody responses during acute and chronic HIV-1 infection. Curr Opin HIV AIDS 2009; 4:373-379.
13. Binley JM, Klasse PJ, Cao Y, Jones I, Markowitz M, Ho DD, et al. Differential regulation of the antibody responses to Gag and Env proteins of human immunodeficiency virus type 1. J Virol 1997; 71:2799-2809. (Pubitemid 27119919)
14. Klasse J, Blomberg J. Patterns of antibodies to human immunodeficiency virus proteins in different subclasses of IgG. J Infect Dis 1987; 156:1026-1030. (Pubitemid 18017087)
15. McDougal JS, Kennedy MS, Nicholson JK, Spira TJ, Jaffe HW, Kaplan JE, et al. Antibody response to human immunodeficiency virus in homosexual men. Relation of antibody specificity, titer, and isotype to clinical status, severity of immunodeficiency, and disease progression. J Clin Invest 1987; 80:316-324.
16. Khalife J, Guy B, Capron M, Kieny MP, Ameisen JC, Montagnier L, et al. Isotypic restriction of the antibody response to human immunodeficiency virus. AIDS Res Hum Retroviruses 1988; 4:3-9. (Pubitemid 18094601)
17. Ljunggren K, Broliden PA, Morfeldt-Manson L, Jondal M, Wahren B. IgG subclass response to HIV in relation to antibody-dependent cellular cytotoxicity at different clinical stages. Clin Exp Immunol 1988; 73:343-347.
18. Wilson KM, Johnson EI, Croom HA, Richards KM, Doughty L, Cunningham PH, et al. Incidence immunoassay for distinguishing recent from established HIV-1 infection in therapy-naive populations. AIDS 2004; 18:2253-2259. (Pubitemid 39620217)
19. Fellay J, Shianna KV, Ge D, Colombo S, Ledergerber B, Weale M, et al. A whole-genome association study of major determinants for host control of HIV-1. Science 2007; 317: 944-947. (Pubitemid 47301321)
20. Fiebig EW, Heldebrant CM, Smith RI, Conrad AJ, Delwart EL, Busch MP. Intermittent low-level viremia in very early primary HIV-1 infection. J Acquir Immune Defic Syndr 2005; 39:133-137. (Pubitemid 40741109)
21. McMichael AJ, Borrow P, Tomaras GD, Goonetilleke N, Haynes BF. The immune response during acute HIV-1 infection: clues for vaccine development. Nat Rev Immunol 2010; 10:11-23.
22. Fiebig EW, Wright DJ, Rawal BD, Garrett PE, Schumacher RT, Peddada L, et al. Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection. AIDS 2003; 17:1871-1879. (Pubitemid 37070272)
23. Gao F, Weaver EA, Lu Z, Li Y, Liao HX, Ma B, et al. Antigenicity and immunogenicity of a synthetic human immunodeficiency virus type 1 group m consensus envelope glycoprotein. J Virol 2005; 79:1154-1163. (Pubitemid 40053898)
24. Liao HX, Chen X, Dixon A, Munshaw S, Moody MA, Zhang R, et al. Characterization of the Plasma Cell Repertoire in Acute HIV-1 Infection (AHI). Retrovirology 2009; 6 (Suppl 3):73.
25. Gatto D, Ruedl C, Odermatt B, Bachmann MF. Rapid response of marginal zone B cells to viral particles. J Immunol 2004; 173:4308-4316. (Pubitemid 39280658)
26. Janssen RS, Satten GA, Stramer SL, Rawal BD, O'Brien TR, Weiblen BJ, et al. New testing strategy to detect early HIV-1 infection for use in incidence estimates and for clinical and prevention purposes. JAMA 1998; 280:42-48. (Pubitemid 28414995)
27. Curtis KA, Kennedy MS, Charurat M, Nasidi A, Delaney K, Spira TJ, Owen MS. Development and characterization of a bead-based, multiplex assay for estimation of recent HIV type 1 infection. AIDS Res Hum Retroviruses [Epub ahead of print] doi:10.1089/aid.2011.0037.
28. Hallett TB, Ghys P, Barnighausen T, Yan P, Garnett GP. Errors in 'BED'-derived estimates of HIV incidence will vary by place, time and age. PLoS One 2009; 4:e5720.
29. Barnighausen T, McWalter TA, Rosner Z, Newell ML, Welte A. HIV incidence estimation using the BED capture enzyme immunoassay: systematic review and sensitivity analysis. Epidemiology 2010; 21:685-697.
30. McDougal JS, Parekh BS, Peterson ML, Branson BM, Dobbs T, Ackers M, et al. Comparison of HIV type 1 incidence observed during longitudinal follow-up with incidence estimated by cross-sectional analysis using the BED capture enzyme immunoassay. AIDS Res Hum Retroviruses 2006; 22:945-952. (Pubitemid 46100678)
31. Wang R, Lagakos SW. Augmented cross-sectional prevalence testing for estimating HIV Incidence. Biometrics 2010; 66:864-874.