The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression

Nature Immunology

Volumn 14, Issue 12, 2013, Pages 1256-1265

  Jelicic, Katija ^a   Cimbro, Raffaello ^a,b   Nawaz, Fatima ^a,c   Huang, Da Wei ^d   Zheng, Xin ^b   Yang, Jun ^b   Lempicki, Richard A ^b   Pascuccio, Massimiliano ^a   Van Ryk, Donald ^a   Schwing, Catherine ^a   Hiatt, Joseph ^a   Okwara, Noreen ^a   Wei, Danlan ^a   Roby, Gregg ^a   David, Antonio ^e   Hwang, Ii Young ^a   Kehrl, John H ^a   Arthos, James ^a   Cicala, Claudia ^a   Fauci, Anthony S ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d SAIC FREDERICK INC   (United States)

^e UNIVERSITY OF MESSINA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; FCRL4 RECEPTOR; GLYCOPROTEIN GP 120; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMORAL IMMUNITY; LYMPHOCYTE CULTURE; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS IMMUNITY;

ANIMALS; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; CHO CELLS; COCULTURE TECHNIQUES; CRICETINAE; CRICETULUS; FLOW CYTOMETRY; HIV ENVELOPE PROTEIN GP120; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; INTEGRINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BINDING; RECEPTORS, FC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84888009485     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2746     Document Type: Article

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