메뉴 건너뛰기




Volumn 9, Issue 3, 2014, Pages 235-241

T follicular helper cells and HIV/SIV-specific antibody responses

Author keywords

Antibodies; HIV; simian immunodeficiency virus; T follicular helper cells

Indexed keywords

CD27 ANTIGEN; CD40 ANTIGEN; CD40 LIGAND; CD45RA ANTIGEN; CD45RO ANTIGEN; CD57 ANTIGEN; CHEMOKINE RECEPTOR CXCR5; GAMMA INTERFERON; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NEUTRALIZING ANTIBODY; SIMIAN IMMUNODEFICIENCY VIRUS VACCINE; STAT1 PROTEIN; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; VACCINE; VIRUS ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY;

EID: 84898545152     PISSN: 1746630X     EISSN: 17466318     Source Type: Journal    
DOI: 10.1097/COH.0000000000000053     Document Type: Review
Times cited : (24)

References (70)
  • 1
    • 84859393693 scopus 로고    scopus 로고
    • Immune-correlates analysis of an HIV-1 vaccine efficacy trial
    • Haynes BF, Gilbert PB, McElrath MJ, et al. Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med 2012; 366:1275-1286.
    • (2012) N Engl J Med , vol.366 , pp. 1275-1286
    • Haynes, B.F.1    Gilbert, P.B.2    McElrath, M.J.3
  • 2
    • 84872809067 scopus 로고    scopus 로고
    • Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2
    • Liao HX, Bonsignori M, Alam SM, et al. Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2. Immunity 2013; 38:176-186.
    • (2013) Immunity , vol.38 , pp. 176-186
    • Liao, H.X.1    Bonsignori, M.2    Alam, S.M.3
  • 3
    • 84877618448 scopus 로고    scopus 로고
    • Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization
    • Georgiev IS, Doria-Rose NA, Zhou T, et al. Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization. Science 2013; 340:751-756.
    • (2013) Science , vol.340 , pp. 751-756
    • Georgiev, I.S.1    Doria-Rose, N.A.2    Zhou, T.3
  • 4
    • 84866493348 scopus 로고    scopus 로고
    • Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
    • Huang J, Ofek G, Laub L, et al. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature 2012; 491:406-412.
    • (2012) Nature , vol.491 , pp. 406-412
    • Huang, J.1    Ofek, G.2    Laub, L.3
  • 5
    • 83455254775 scopus 로고    scopus 로고
    • Structure of HIV-1 gp120V1/V2 domain with broadly neutralizing antibody PG9
    • McLellan JS, Pancera M, Carrico C, et al. Structure of HIV-1 gp120V1/V2 domain with broadly neutralizing antibody PG9. Nature 2011; 480:336-343.
    • (2011) Nature , vol.480 , pp. 336-343
    • McLellan, J.S.1    Pancera, M.2    Carrico, C.3
  • 6
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH)
    • Crotty S. Follicular helper CD4 T cells (TFH). Annu Rev Immunol 2011; 29:621-663.
    • (2011) Annu Rev Immunol , vol.29 , pp. 621-663
    • Crotty, S.1
  • 7
    • 84873640954 scopus 로고    scopus 로고
    • Transcriptional regulation of follicular T-helper (Tfh) cells
    • Liu X, Nurieva RI, Dong C. Transcriptional regulation of follicular T-helper (Tfh) cells. Immunol Rev 2013; 252:139-145.
    • (2013) Immunol Rev , vol.252 , pp. 139-145
    • Liu, X.1    Nurieva, R.I.2    Dong, C.3
  • 8
    • 79956079578 scopus 로고    scopus 로고
    • Germinal center B and follicular helper T cells: Siblings cousins or just good friends?
    • Nutt SL, Tarlinton DM. Germinal center B and follicular helper T cells: siblings, cousins or just good friends? Nat Immunol 2011; 12:472-477.
    • (2011) Nat Immunol , vol.12 , pp. 472-477
    • Nutt, S.L.1    Tarlinton, D.M.2
  • 9
    • 27744498868 scopus 로고    scopus 로고
    • Follicular B helper T cells in antibody responses and autoimmunity
    • Vinuesa CG, Tangye SG, Moser B, et al. Follicular B helper T cells in antibody responses and autoimmunity. Nat Rev Immunol 2005; 5:853-865.
    • (2005) Nat Rev Immunol , vol.5 , pp. 853-865
    • Vinuesa, C.G.1    Tangye, S.G.2    Moser, B.3
  • 10
    • 79951672553 scopus 로고    scopus 로고
    • Regulation of T follicular helper cell formation and function by antigen presenting cells
    • Deenick EK, Ma CS, Brink R, et al. Regulation of T follicular helper cell formation and function by antigen presenting cells. Curr Opin Immunol 2011; 23:111-118.
    • (2011) Curr Opin Immunol , vol.23 , pp. 111-118
    • Deenick, E.K.1    Ma, C.S.2    Brink, R.3
  • 11
    • 38049144850 scopus 로고    scopus 로고
    • Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1 high germinal center-associated subpopulation
    • Haynes NM, Allen CD, Lesley R, et al. Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1 high germinal center-associated subpopulation. J Immunol 2007; 179:5099-5108.
    • (2007) J Immunol , vol.179 , pp. 5099-5108
    • Haynes, N.M.1    Allen, C.D.2    Lesley, R.3
  • 12
    • 69249101229 scopus 로고    scopus 로고
    • Bcl6 mediates the development of T follicular helper cells
    • Nurieva RI, Chung Y, Martinez GJ, et al. Bcl6 mediates the development of T follicular helper cells. Science 2009; 325:1001-1005.
    • (2009) Science , vol.325 , pp. 1001-1005
    • Nurieva, R.I.1    Chung, Y.2    Martinez, G.J.3
  • 13
    • 62849126473 scopus 로고    scopus 로고
    • The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding
    • Fazilleau N, McHeyzer-Williams LJ, Rosen H, et al. The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding. Nat Immunol 2009; 10:375-384.
    • (2009) Nat Immunol , vol.10 , pp. 375-384
    • Fazilleau, N.1    McHeyzer-Williams, L.J.2    Rosen, H.3
  • 14
    • 80051618656 scopus 로고    scopus 로고
    • Cutting edge: Dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation
    • Goenka R, Barnett LG, Silver JS, et al. Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation. J Immunol 2011; 187:1091-1095.
    • (2011) J Immunol , vol.187 , pp. 1091-1095
    • Goenka, R.1    Barnett, L.G.2    Silver, J.S.3
  • 15
    • 24744448228 scopus 로고    scopus 로고
    • Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help
    • Hardtke S, Ohl L, Forster R. Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help. Blood 2005; 106:1924-1931.
    • (2005) Blood , vol.106 , pp. 1924-1931
    • Hardtke, S.1    Ohl, L.2    Forster, R.3
  • 16
    • 79959328032 scopus 로고    scopus 로고
    • ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
    • Choi YS, Kageyama R, Eto D, et al. ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity 2011; 34:932-946.
    • (2011) Immunity , vol.34 , pp. 932-946
    • Choi, Y.S.1    Kageyama, R.2    Eto, D.3
  • 17
    • 8544229946 scopus 로고    scopus 로고
    • SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1
    • Cannons JL, Yu LJ, Hill B, et al. SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1. Immunity 2004; 21:693-706.
    • (2004) Immunity , vol.21 , pp. 693-706
    • Cannons, J.L.1    Yu, L.J.2    Hill, B.3
  • 18
    • 53649107278 scopus 로고    scopus 로고
    • SAP-controlled T-B cell interactions underlie germinal centre formation
    • Qi H, Cannons JL, Klauschen F, et al. SAP-controlled T-B cell interactions underlie germinal centre formation. Nature 2008; 455:764-769.
    • (2008) Nature , vol.455 , pp. 764-769
    • Qi, H.1    Cannons, J.L.2    Klauschen, F.3
  • 19
    • 79956104027 scopus 로고    scopus 로고
    • Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells
    • Fahey LM, Wilson EB, Elsaesser H, et al. Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells. J Exp Med 2011; 208:987-999.
    • (2011) J Exp Med , vol.208 , pp. 987-999
    • Fahey, L.M.1    Wilson, E.B.2    Elsaesser, H.3
  • 20
    • 65549134481 scopus 로고    scopus 로고
    • T follicular helper cells differentiate from Th2 cells in response to helminth antigens
    • Glatman Zaretsky A, Taylor JJ, King IL, et al. T follicular helper cells differentiate from Th2 cells in response to helminth antigens. J Exp Med 2009; 206:991-999.
    • (2009) J Exp Med , vol.206 , pp. 991-999
    • Glatman Zaretsky, A.1    Taylor, J.J.2    King, I.L.3
  • 21
    • 46749151286 scopus 로고    scopus 로고
    • Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
    • Nurieva RI, Chung Y, Hwang D, et al. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity 2008; 29:138-149.
    • (2008) Immunity , vol.29 , pp. 138-149
    • Nurieva, R.I.1    Chung, Y.2    Hwang, D.3
  • 22
    • 81055157812 scopus 로고    scopus 로고
    • Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection
    • Harker JA, Lewis GM, Mack L, et al. Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection. Science 2011; 334:825-829.
    • (2011) Science , vol.334 , pp. 825-829
    • Harker, J.A.1    Lewis, G.M.2    Mack, L.3
  • 23
    • 79956125257 scopus 로고    scopus 로고
    • + effector and central memory T cells
    • + effector and central memory T cells. Nat Immunol 2011; 12:467-471.
    • (2011) Nat Immunol , vol.12 , pp. 467-471
    • Pepper, M.1    Jenkins, M.K.2
  • 24
    • 84881252552 scopus 로고    scopus 로고
    • T follicular helper cell dynamics in germinal centers
    • Shulman Z, Gitlin AD, Targ S, et al. T follicular helper cell dynamics in germinal centers. Science 2013; 341:673-677.
    • (2013) Science , vol.341 , pp. 673-677
    • Shulman, Z.1    Gitlin, A.D.2    Targ, S.3
  • 25
    • 84859897308 scopus 로고    scopus 로고
    • The development and fate of follicular helper T cells defined by an IL-21 reporter mouse
    • Luthje K, Kallies A, Shimohakamada Y, et al. The development and fate of follicular helper T cells defined by an IL-21 reporter mouse. Nat Immunol 2012; 13:491-498.
    • (2012) Nat Immunol , vol.13 , pp. 491-498
    • Luthje, K.1    Kallies, A.2    Shimohakamada, Y.3
  • 26
    • 84859487740 scopus 로고    scopus 로고
    • STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function
    • Nurieva RI, Podd A, Chen Y, et al. STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function. J Biol Chem 2012; 287:11234-11239.
    • (2012) J Biol Chem , vol.287 , pp. 11234-11239
    • Nurieva, R.I.1    Podd, A.2    Chen, Y.3
  • 27
    • 84891765853 scopus 로고    scopus 로고
    • Regulatory mechanisms that control T-follicular helper and T-helper 1 cell flexibility
    • Weinmann AS. Regulatory mechanisms that control T-follicular helper and T-helper 1 cell flexibility. Immunol Cell Biol 2013; 92:34-39.
    • (2013) Immunol Cell Biol , vol.92 , pp. 34-39
    • Weinmann, A.S.1
  • 28
    • 0034129629 scopus 로고    scopus 로고
    • Signaling and transcription in T helper development
    • Murphy KM, Ouyang W, Farrar JD, et al. Signaling and transcription in T helper development. Annu Rev Immunol 2000; 18:451-494.
    • (2000) Annu Rev Immunol , vol.18 , pp. 451-494
    • Murphy, K.M.1    Ouyang, W.2    Farrar, J.D.3
  • 29
    • 84875417243 scopus 로고    scopus 로고
    • Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation
    • Choi YS, Eto D, Yang JA, et al. Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation. J Immunol 2013; 190:3049-3053.
    • (2013) J Immunol , vol.190 , pp. 3049-3053
    • Choi, Y.S.1    Eto, D.2    Yang, J.A.3
  • 30
    • 77957256910 scopus 로고    scopus 로고
    • The elusive identity of T follicular helper cells
    • Yu D, Vinuesa CG. The elusive identity of T follicular helper cells. Trends Immunol 2010; 31:377-383.
    • (2010) Trends Immunol , vol.31 , pp. 377-383
    • Yu, D.1    Vinuesa, C.G.2
  • 31
    • 84875549975 scopus 로고    scopus 로고
    • Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype
    • Baumjohann D, Preite S, Reboldi A, et al. Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype. Immunity 2013; 38:596-605.
    • (2013) Immunity , vol.38 , pp. 596-605
    • Baumjohann, D.1    Preite, S.2    Reboldi, A.3
  • 32
    • 84860336456 scopus 로고    scopus 로고
    • CD80 expression on B cells regulates murine T follicular helper development, germinal center B cell survival, and plasma cell generation
    • Good-Jacobson KL, Song E, Anderson S, et al. CD80 expression on B cells regulates murine T follicular helper development, germinal center B cell survival, and plasma cell generation. J Immunol 2012; 188:4217-4225.
    • (2012) J Immunol , vol.188 , pp. 4217-4225
    • Good-Jacobson, K.L.1    Song, E.2    Anderson, S.3
  • 33
    • 84870283741 scopus 로고    scopus 로고
    • B and T cells collaborate in antiviral responses via IL-6 IL-21 and transcriptional activator and coactivator Oct2 and OBF-1
    • Karnowski A, Chevrier S, Belz GT, et al. B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1. J Exp Med 2012; 209:2049-2064.
    • (2012) J Exp Med , vol.209 , pp. 2049-2064
    • Karnowski, A.1    Chevrier, S.2    Belz, G.T.3
  • 34
    • 76949091588 scopus 로고    scopus 로고
    • Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84
    • Cannons JL, Qi H, Lu KT, et al. Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84. Immunity 2010; 32:253-265.
    • (2010) Immunity , vol.32 , pp. 253-265
    • Cannons, J.L.1    Qi, H.2    Lu, K.T.3
  • 35
    • 84859415408 scopus 로고    scopus 로고
    • + T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape
    • + T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape. J Immunol 2012; 188:3247-3256.
    • (2012) J Immunol , vol.188 , pp. 3247-3256
    • Hong, J.J.1    Amancha, P.K.2    Rogers, K.3
  • 36
    • 0034606359 scopus 로고    scopus 로고
    • Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
    • Breitfeld D, Ohl L, Kremmer E, et al. Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production. J Exp Med 2000; 192:1545-1552.
    • (2000) J Exp Med , vol.192 , pp. 1545-1552
    • Breitfeld, D.1    Ohl, L.2    Kremmer, E.3
  • 37
    • 2942755979 scopus 로고    scopus 로고
    • T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells
    • Chtanova T, Tangye SG, Newton R, et al. T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells. J Immunol 2004; 173:68-78.
    • (2004) J Immunol , vol.173 , pp. 68-78
    • Chtanova, T.1    Tangye, S.G.2    Newton, R.3
  • 38
    • 4644325602 scopus 로고    scopus 로고
    • Unique gene expression program of human germinal center T helper cells
    • Kim CH, Lim HW, Kim JR, et al. Unique gene expression program of human germinal center T helper cells. Blood 2004; 104:1952-1960.
    • (2004) Blood , vol.104 , pp. 1952-1960
    • Kim, C.H.1    Lim, H.W.2    Kim, J.R.3
  • 39
    • 84865395104 scopus 로고    scopus 로고
    • CD4 T follicular helper cell dynamics during SIV infection
    • Petrovas C, Yamamoto T, Gerner MY, et al. CD4 T follicular helper cell dynamics during SIV infection. J Clin Invest 2012; 122:3281-3294.
    • (2012) J Clin Invest , vol.122 , pp. 3281-3294
    • Petrovas, C.1    Yamamoto, T.2    Gerner, M.Y.3
  • 42
    • 79961151137 scopus 로고    scopus 로고
    • Foxp3+ follicular regulatory T cells control the germinal center response
    • Linterman MA, Pierson W, Lee SK, et al. Foxp3+ follicular regulatory T cells control the germinal center response. Nat Med 2011; 17:975-982.
    • (2011) Nat Med , vol.17 , pp. 975-982
    • Linterman, M.A.1    Pierson, W.2    Lee, S.K.3
  • 45
    • 84859711533 scopus 로고    scopus 로고
    • Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation
    • Kroenke MA, Eto D, Locci M, et al. Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation. J Immunol 2012; 188:3734-3744.
    • (2012) J Immunol , vol.188 , pp. 3734-3744
    • Kroenke, M.A.1    Eto, D.2    Locci, M.3
  • 46
    • 84859711557 scopus 로고    scopus 로고
    • Functional STAT3 deficiency compromises the generation of human T follicular helper cells
    • Ma CS, Avery DT, Chan A, et al. Functional STAT3 deficiency compromises the generation of human T follicular helper cells. Blood 2012; 119:3997-4008.
    • (2012) Blood , vol.119 , pp. 3997-4008
    • Ma, C.S.1    Avery, D.T.2    Chan, A.3
  • 47
    • 79952216365 scopus 로고    scopus 로고
    • Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections
    • Zeng M, Smith AJ, Wietgrefe SW, et al. Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections. J Clin Invest 2011; 121:998-1008.
    • (2011) J Clin Invest , vol.121 , pp. 998-1008
    • Zeng, M.1    Smith, A.J.2    Wietgrefe, S.W.3
  • 48
    • 84865997747 scopus 로고    scopus 로고
    • Expansion of HIV-specific T follicular helper cells in chronic HIV infection
    • Lindqvist M, van Lunzen J, Soghoian DZ, et al. Expansion of HIV-specific T follicular helper cells in chronic HIV infection. J Clin Invest 2012; 122:3271-3280.
    • (2012) J Clin Invest , vol.122 , pp. 3271-3280
    • Lindqvist, M.1    Van Lunzen, J.2    Soghoian, D.Z.3
  • 49
    • 84874519282 scopus 로고    scopus 로고
    • Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production
    • Perreau M, Savoye AL, De Crignis E, et al. Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production. J Exp Med 2013; 210:143-156.
    • (2013) J Exp Med , vol.210 , pp. 143-156
    • Perreau, M.1    Savoye, A.L.2    De Crignis, E.3
  • 50
    • 0028244846 scopus 로고
    • Follicular dendritic cells retain HIV-1 particles on their plasma membrane, but are not productively infected in asymptomatic patients with follicular hyperplasia
    • Schmitz J, van Lunzen J, Tenner-Racz K, et al. Follicular dendritic cells retain HIV-1 particles on their plasma membrane, but are not productively infected in asymptomatic patients with follicular hyperplasia. J Immunol 1994; 153: 1352-1359.
    • (1994) J Immunol , vol.153 , pp. 1352-1359
    • Schmitz, J.1    Van Lunzen, J.2    Tenner-Racz, K.3
  • 51
    • 0036499181 scopus 로고    scopus 로고
    • Follicular dendritic cells and the persistence of HIV infectivity: The role of antibodies and Fcgamma receptors
    • Smith-Franklin BA, Keele BF, Tew JG, et al. Follicular dendritic cells and the persistence of HIV infectivity: the role of antibodies and Fcgamma receptors. J Immunol 2002; 168:2408-2414.
    • (2002) J Immunol , vol.168 , pp. 2408-2414
    • Smith-Franklin, B.A.1    Keele, B.F.2    Tew, J.G.3
  • 52
    • 84878454838 scopus 로고    scopus 로고
    • Inadequate T follicular cell help impairs B cell immunity during HIV infection
    • Cubas RA, Mudd JC, Savoye AL, et al. Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nat Med 2013; 19:494-499.
    • (2013) Nat Med , vol.19 , pp. 494-499
    • Cubas, R.A.1    Mudd, J.C.2    Savoye, A.L.3
  • 53
    • 77952557954 scopus 로고    scopus 로고
    • PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells
    • Good-Jacobson KL, Szumilas CG, Chen L, et al. PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells. Nat Immunol 2010; 11:535-542.
    • (2010) Nat Immunol , vol.11 , pp. 535-542
    • Good-Jacobson, K.L.1    Szumilas, C.G.2    Chen, L.3
  • 55
    • 0023069479 scopus 로고
    • B-cell stimulatory factor-1/interleukin 4
    • Paul WE, Ohara J. B-cell stimulatory factor-1/interleukin 4. Annu Rev Immunol 1987; 5:429-459.
    • (1987) Annu Rev Immunol , vol.5 , pp. 429-459
    • Paul, W.E.1    Ohara, J.2
  • 56
    • 0027516822 scopus 로고
    • Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS
    • Embretson J, Zupancic M, Ribas JL, et al. Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature 1993; 362:359-362.
    • (1993) Nature , vol.362 , pp. 359-362
    • Embretson, J.1    Zupancic, M.2    Ribas, J.L.3
  • 57
    • 0027538456 scopus 로고
    • HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease
    • Pantaleo G, Graziosi C, Demarest JF, et al. HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature 1993; 362:355-358.
    • (1993) Nature , vol.362 , pp. 355-358
    • Pantaleo, G.1    Graziosi, C.2    Demarest, J.F.3
  • 58
    • 0031011147 scopus 로고    scopus 로고
    • Germinal centre CD4+ T cells are an important site of HIV replication in vivo
    • Hufert FT, van Lunzen J, Janossy G, et al. Germinal centre CD4+ T cells are an important site of HIV replication in vivo. AIDS 1997; 11:849-857.
    • (1997) AIDS , vol.11 , pp. 849-857
    • Hufert, F.T.1    Van Lunzen, J.2    Janossy, G.3
  • 59
    • 84875539507 scopus 로고    scopus 로고
    • Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques
    • Xu Y, Weatherall C, Bailey M, et al. Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques. J Virol 2013; 87:3760-3773.
    • (2013) J Virol , vol.87 , pp. 3760-3773
    • Xu, Y.1    Weatherall, C.2    Bailey, M.3
  • 60
    • 84876797103 scopus 로고    scopus 로고
    • Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
    • Liao HX, Lynch R, Zhou T, et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature 2013; 496:469-476.
    • (2013) Nature , vol.496 , pp. 469-476
    • Liao, H.X.1    Lynch, R.2    Zhou, T.3
  • 61
    • 78149477766 scopus 로고    scopus 로고
    • Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter
    • Victora GD, Schwickert TA, Fooksman DR, et al. Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter. Cell 2010; 143:592-605.
    • (2010) Cell , vol.143 , pp. 592-605
    • Victora, G.D.1    Schwickert, T.A.2    Fooksman, D.R.3
  • 62
    • 79958255209 scopus 로고    scopus 로고
    • A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center
    • Schwickert TA, Victora GD, Fooksman DR, et al. A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center. J Exp Med 2011; 208:1243-1252.
    • (2011) J Exp Med , vol.208 , pp. 1243-1252
    • Schwickert, T.A.1    Victora, G.D.2    Fooksman, D.R.3
  • 63
    • 84875129611 scopus 로고    scopus 로고
    • Induction of ICOS+CXCR3+ CXCR5+ TH cells correlates with antibody responses to influenza vaccination
    • Bentebibel SE, Lopez S, Obermoser G, et al. Induction of ICOS+CXCR3+ CXCR5+ TH cells correlates with antibody responses to influenza vaccination. Sci Transl Med 2013; 5:176ra32.
    • (2013) Sci Transl Med , vol.5
    • Bentebibel, S.E.1    Lopez, S.2    Obermoser, G.3
  • 64
    • 84893746319 scopus 로고    scopus 로고
    • Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection
    • Boswell KL, Paris P, Boritz E, et al. Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection. PLoS Pathog 2014; 10:e1003853.
    • (2014) PLoS Pathog , vol.10
    • Boswell, K.L.1    Paris, P.2    Boritz, E.3
  • 65
    • 84885741984 scopus 로고    scopus 로고
    • + T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure
    • + T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure. Immunity 2013; 39:770-781.
    • (2013) Immunity , vol.39 , pp. 770-781
    • He, J.1    Tsai, L.M.2    Leong, Y.A.3
  • 66
    • 84885743368 scopus 로고    scopus 로고
    • + memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses
    • + memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses. Immunity 2013; 39:758-769.
    • (2013) Immunity , vol.39 , pp. 758-769
    • Locci, M.1    Havenar-Daughton, C.2    Landais, E.3
  • 67
    • 78751690647 scopus 로고    scopus 로고
    • + T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion
    • + T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion. Immunity 2011; 34:108-121.
    • (2011) Immunity , vol.34 , pp. 108-121
    • Morita, R.1    Schmitt, N.2    Bentebibel, S.E.3
  • 68
    • 84864555009 scopus 로고    scopus 로고
    • Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009H1N1/09 vaccine
    • Pallikkuth S, Parmigiani A, Silva SY, et al. Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009H1N1/09 vaccine. Blood 2012; 120:985-993.
    • (2012) Blood , vol.120 , pp. 985-993
    • Pallikkuth, S.1    Parmigiani, A.2    Silva, S.Y.3
  • 69
    • 84883334148 scopus 로고    scopus 로고
    • + ICOS1 +IL-21 + T cells expand after vaccination, exert helper function, and predict antibody responses
    • + ICOS1 +IL-21 + T cells expand after vaccination, exert helper function, and predict antibody responses. Proc Natl Acad Sci USA 2013; 110:14330-14335.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 14330-14335
    • Spensieri, F.1    Borgogni, E.2    Zedda, L.3
  • 70
    • 84876780521 scopus 로고    scopus 로고
    • + T cells with commitment to T follicular helper-and T helper 1-cell lineages are generated after acute viral infection
    • + T cells with commitment to T follicular helper-and T helper 1-cell lineages are generated after acute viral infection. Immunity 2013; 38:805-817.
    • (2013) Immunity , vol.38 , pp. 805-817
    • Hale, J.S.1    Youngblood, B.2    Latner, D.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.