The impact of B-cell perturbations on pneumococcal conjugate vaccine response in HIV-infected adults

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Johannesson, Thomas G ^a   Søgaard, Ole S ^a   Tolstrup, Martin ^a   Petersen, Mikkel S ^a   Bernth Jensen, Jens M ^a   Østergaard, Lars ^a   Erikstrup, Christian ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AGATOLIMOD; ANTIRETROVIRUS AGENT; IMMUNOGLOBULIN G; PLACEBO; PNEUMOCOCCUS VACCINE; VIRUS RNA;

ADULT; ANTIBODY RESPONSE; ARTICLE; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; DRUG RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMORAL IMMUNITY; IMMUNOGENICITY; IMMUNOGLOBULIN BLOOD LEVEL; LYMPHOCYTE SUBPOPULATION; MAJOR CLINICAL STUDY; MALE; MEMORY CELL; PNEUMOCOCCAL INFECTION; PRE B LYMPHOCYTE; VACCINATION;

ADULT; ANTI-HIV AGENTS; ANTIBODIES, BACTERIAL; B-LYMPHOCYTES; CD4 LYMPHOCYTE COUNT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HIV INFECTIONS; HUMANS; IMMUNOLOGIC MEMORY; MALE; MIDDLE AGED; PNEUMOCOCCAL VACCINES;

EID: 84864483910     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042307     Document Type: Article

References (32)

1. Sogaard OS, Lohse N, Gerstoft J, Kronborg G, Ostergaard L, et al. (2008) Hospitalization for pneumonia among individuals with and without HIV infection, 1995-2007: a Danish population-based, nationwide cohort study. Clin Infect Dis 47: 1345-1353.
2. Kohli R, Lo Y, Homel P, Flanigan TP, Gardner LI, et al. (2006) Bacterial pneumonia, HIV therapy, and disease progression among HIV-infected women in the HIV epidemiologic research (HER) study. Clin Infect Dis 43: 90-98.
3. Nuorti JP, Butler JC, Gelling L, Kool JL, Reingold AL, et al. (2000) Epidemiologic relation between HIV and invasive pneumococcal disease in San Francisco County, California. Ann Intern Med 132: 182-190.
4. Kaplan JE, Benson C, Holmes KH, Brooks JT, Pau A, et al. (2009) Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. MMWR Recomm Rep 58: 1-207; quiz CE201-204.
5. Barry PM, Zetola N, Keruly JC, Moore RD, Gebo KA, et al. (2006) Invasive pneumococcal disease in a cohort of HIV-infected adults: incidence and risk factors, 1990-2003. AIDS 20: 437-444.
6. Dworkin MS, Ward JW, Hanson DL, Jones JL, Kaplan JE, (2001) Pneumococcal disease among human immunodeficiency virus-infected persons: incidence, risk factors, and impact of vaccination. Clin Infect Dis 32: 794-800.
7. Falco V, Jordano Q, Cruz MJ, Len O, Ribera E, et al. (2006) Serological response to pneumococcal vaccination in HAART-treated HIV-infected patients: one year follow-up study. Vaccine 24: 2567-2574.
8. Sogaard OS, Schonheyder HC, Bukh AR, Harboe ZB, Rasmussen TA, et al. (2010) Pneumococcal conjugate vaccination in persons with HIV: the effect of highly active antiretroviral therapy. AIDS 24: 1315-1322.
9. Crum-Cianflone NF, Huppler Hullsiek K, Roediger M, Ganesan A, Patel S, et al. (2010) A randomized clinical trial comparing revaccination with pneumococcal conjugate vaccine to polysaccharide vaccine among HIV-infected adults. J Infect Dis 202: 1114-1125.
10. Madhi SA, Klugman KP, Kuwanda L, Cutland C, Kayhty H, et al. (2009) Quantitative and qualitative anamnestic immune responses to pneumococcal conjugate vaccine in HIV-infected and HIV-uninfected children 5 years after vaccination. J Infect Dis 199: 1168-1176.
11. Malley R, (2010) Antibody and cell-mediated immunity to Streptococcus pneumoniae: implications for vaccine development. J Mol Med 88: 135-142.
12. Moir S, Fauci AS, (2009) B cells in HIV infection and disease. Nat Rev Immunol 9: 235-245.
13. Shen X, Tomaras GD (2010) Alterations of the B-Cell Response by HIV-1 Replication. Curr HIV/AIDS Rep.
14. Moir S, Buckner CM, Ho J, Wang W, Chen J, et al. (2010) B cells in early and chronic HIV infection: evidence for preservation of immune function associated with early initiation of antiretroviral therapy. Blood 116: 5571-5579.
15. Kruetzmann S, Rosado MM, Weber H, Germing U, Tournilhac O, et al. (2003) Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen. J Exp Med 197: 939-945.
16. Weill JC, Weller S, Reynaud CA, (2009) Human marginal zone B cells. Annu Rev Immunol 27: 267-285.
17. Weller S, Braun MC, Tan BK, Rosenwald A, Cordier C, et al. (2004) Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire. Blood 104: 3647-3654.
18. Fournier AM, Baillat V, Alix-Panabieres C, Fondere JM, Merle C, et al. (2002) Dynamics of spontaneous HIV-1 specific and non-specific B-cell responses in patients receiving antiretroviral therapy. AIDS 16: 1755-1760.
19. Hart M, Steel A, Clark SA, Moyle G, Nelson M, et al. (2007) Loss of discrete memory B cell subsets is associated with impaired immunization responses in HIV-1 infection and may be a risk factor for invasive pneumococcal disease. J Immunol 178: 8212-8220.
20. Chong Y, Ikematsu H, Kikuchi K, Yamamoto M, Murata M, et al. (2004) Selective CD27+ (memory) B cell reduction and characteristic B cell alteration in drug-naive and HAART-treated HIV type 1-infected patients. AIDS Res Hum Retroviruses 20: 219-226.
21. Moir S, Malaspina A, Ho J, Wang W, Dipoto AC, et al. (2008) Normalization of B cell counts and subpopulations after antiretroviral therapy in chronic HIV disease. J Infect Dis 197: 572-579.
22. French N, Gordon SB, Mwalukomo T, White SA, Mwafulirwa G, et al. (2010) A trial of a 7-valent pneumococcal conjugate vaccine in HIV-infected adults. N Engl J Med 362: 812-822.
23. Sogaard OS, Lohse N, Harboe ZB, Offersen R, Bukh AR, et al. (2010) Improving the immunogenicity of pneumococcal conjugate vaccine in HIV-infected adults with a toll-like receptor 9 agonist adjuvant: a randomized, controlled trial. Clin Infect Dis 51: 42-50.
24. Konradsen HB, Sorensen UB, Henrichsen J, (1993) A modified enzyme-linked immunosorbent assay for measuring type-specific anti-pneumococcal capsular polysaccharide antibodies. J Immunol Methods 164: 13-20.
25. Skovsted IC, Kerrn MB, Sonne-Hansen J, Sauer LE, Nielsen AK, et al. (2007) Purification and structure characterization of the active component in the pneumococcal 22F polysaccharide capsule used for adsorption in pneumococcal enzyme-linked immunosorbent assays. Vaccine 25: 6490-6500.
26. Martinez JE, Clutterbuck EA, Li H, Romero-Steiner S, Carlone GM, (2006) Evaluation of multiplex flow cytometric opsonophagocytic assays for determination of functional anticapsular antibodies to Streptococcus pneumoniae. Clin Vaccine Immunol 13: 459-466.
27. Warnatz K, Schlesier M, (2008) Flowcytometric phenotyping of common variable immunodeficiency. Cytometry B Clin Cytom 74: 261-271.
28. Sanz I, Wei C, Lee FE, Anolik J, (2008) Phenotypic and functional heterogeneity of human memory B cells. Semin Immunol 20: 67-82.
29. Titanji K, De Milito A, Cagigi A, Thorstensson R, Grutzmeier S, et al. (2006) Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection. Blood 108: 1580-1587.
30. Rabian C, Tschope I, Lesprit P, Katlama C, Molina JM, et al. (2010) Cellular CD4 T cell responses to the diphtheria-derived carrier protein of conjugated pneumococcal vaccine and antibody response to pneumococcal vaccination in HIV-infected adults. Clin Infect Dis 50: 1174-1183.
31. Morris L, Binley JM, Clas BA, Bonhoeffer S, Astill TP, et al. (1998) HIV-1 antigen-specific and-nonspecific B cell responses are sensitive to combination antiretroviral therapy. J Exp Med 188: 233-245.
32. Subramaniam KS, Segal R, Lyles RH, Rodriguez-Barradas MC, Pirofski LA, (2003) Qualitative change in antibody responses of human immunodeficiency virus-infected individuals to pneumococcal capsular polysaccharide vaccination associated with highly active antiretroviral therapy. J Infect Dis 187: 758-768.