Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

Journal of Experimental Medicine

Volumn 208, Issue 11, 2011, Pages 2237-2249

  Liao, Hua Xin ^a   Chen, Xi ^a   Munshaw, Supriya ^a   Zhang, Ruijun ^a   Marshall, Dawn J ^a   Vandergrift, Nathan ^a   Whitesides, John F ^a   Lu, Xiaozhi ^a   Yu, Jae Sung ^a   Hwang, Kwan Ki ^a   Gao, Feng ^a   Markowitz, Martin ^b   Heath, Sonya L ^c   Bar, Katharine J ^c   Goepfert, Paul A ^c   Montefiori, David C ^a   Shaw, George C ^c   Alam, S Munir ^a   Margolis, David M ^d   Denny, Thomas N ^a   Boyd, Scott D ^e   Marshal, Eleanor ^e   Egholm, Michael ^f   Simen, Birgitte B ^f   Hanczaruk, Bozena ^f   Fire, Andrew Z ^e   Voss, Gerald ^g   Kelsoe, Garnett ^a   Tomaras, Georgia D ^a   Moody, M Anthony ^a   Kepler, Thomas B ^a   Haynes, Barton F ^a   more..

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b AARON DIAMOND AIDS RESEARCH CENTER   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

^e STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f 454 Life Sciences ^*  (United States)

^g GLAXOSMITHKLINE BIOLOGICALS   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 41;

ADULT; ANTIBODY ISOLATION; ANTIGEN BINDING; ARTICLE; CELL ISOLATION; CLINICAL ARTICLE; ENVELOPE GENE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN TISSUE; IMMUNOSTIMULATION; INFECTION; MALE; MEMORY CELL; PLASMA CELL; PRIORITY JOURNAL; SOMATIC MUTATION; VIRUS MUTATION;

ADULT; CELL LINEAGE; FEMALE; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS; MALE; MUTATION; PHYLOGENY; PLASMA CELLS; SEQUENCE ANALYSIS, DNA; VIRAL LOAD; VIREMIA;

EID: 80055118908     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20110363     Document Type: Article

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