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Volumn 38, Issue 1, 2017, Pages 71-86

Epidemic and Emerging Coronaviruses (Severe Acute Respiratory Syndrome and Middle East Respiratory Syndrome)

Author keywords

Clinical features; MERS CoV; Pathogenesis; Respiratory tract infections; SARS CoV; Treatment

Indexed keywords

ALPHA2A INTERFERON; ALPHA2B INTERFERON; ALPHA2B INTERFERON PLUS RIBAVIRIN; BETA INTERFERON; BETA1A INTERFERON; CHLOROQUINE; CORTICOSTEROID; HYDROCORTISONE; INTERFERON BETA SERINE; LOPINAVIR PLUS RITONAVIR; METHYLPREDNISOLONE; MONOCLONAL ANTIBODY; MYCOPHENOLIC ACID; NITAZOXANIDE; PLACEBO; POLYCLONAL ANTIBODY; RIBAVIRIN; VIRUS ANTIBODY;

EID: 85007621961     PISSN: 02725231     EISSN: 15578216     Source Type: Journal    
DOI: 10.1016/j.ccm.2016.11.007     Document Type: Review
Times cited : (110)

References (146)
  • 1
    • 84957818744 scopus 로고    scopus 로고
    • Coronaviruses - drug discovery and therapeutic options
    • 1 Zumla, A., Chan, J.F., Azhar, E.I., et al. Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov 15:5 (2016), 327–347.
    • (2016) Nat Rev Drug Discov , vol.15 , Issue.5 , pp. 327-347
    • Zumla, A.1    Chan, J.F.2    Azhar, E.I.3
  • 2
    • 0038523806 scopus 로고    scopus 로고
    • Identification of a novel coronavirus in patients with severe acute respiratory syndrome
    • 2 Drosten, C., Gunther, S., Preiser, W., et al. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 348 (2003), 1967–1976.
    • (2003) N Engl J Med , vol.348 , pp. 1967-1976
    • Drosten, C.1    Gunther, S.2    Preiser, W.3
  • 3
    • 0038076030 scopus 로고    scopus 로고
    • A novel coronavirus associated with severe acute respiratory syndrome
    • 3 Ksiazek, T.G., Erdman, D., Goldsmith, C.S., et al., SARS Working Group. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med 348 (2003), 1953–1966.
    • (2003) N Engl J Med , vol.348 , pp. 1953-1966
    • Ksiazek, T.G.1    Erdman, D.2    Goldsmith, C.S.3
  • 4
    • 0042198682 scopus 로고    scopus 로고
    • Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome
    • 4 Kuiken, T., Fouchier, R.A., Schutten, M., et al. Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome. Lancet 362 (2003), 263–270.
    • (2003) Lancet , vol.362 , pp. 263-270
    • Kuiken, T.1    Fouchier, R.A.2    Schutten, M.3
  • 5
    • 0013074820 scopus 로고    scopus 로고
    • A major outbreak of severe acute respiratory syndrome in Hong Kong
    • 5 Lee, N., Hui, D.S., Wu, A., et al. A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med 348 (2003), 1986–1994.
    • (2003) N Engl J Med , vol.348 , pp. 1986-1994
    • Lee, N.1    Hui, D.S.2    Wu, A.3
  • 6
    • 0013255608 scopus 로고    scopus 로고
    • A cluster of cases of severe acute respiratory syndrome in Hong Kong
    • 6 Tsang, K.W., Ho, P.L., Ooi, G.C., et al. A cluster of cases of severe acute respiratory syndrome in Hong Kong. N Engl J Med 348 (2003), 1977–1985.
    • (2003) N Engl J Med , vol.348 , pp. 1977-1985
    • Tsang, K.W.1    Ho, P.L.2    Ooi, G.C.3
  • 7
    • 0042354620 scopus 로고    scopus 로고
    • Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China
    • 7 Zhao, Z., Zhang, F., Xu, M., et al. Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China. J Med Microbiol 52 (2003), 715–720.
    • (2003) J Med Microbiol , vol.52 , pp. 715-720
    • Zhao, Z.1    Zhang, F.2    Xu, M.3
  • 8
    • 2542611561 scopus 로고    scopus 로고
    • Epidemiologic clues to SARS origin in China
    • 8 Xu, R.H., He, J.F., Evans, M.R., et al. Epidemiologic clues to SARS origin in China. Emerg Infect Dis 10 (2004), 1030–1037.
    • (2004) Emerg Infect Dis , vol.10 , pp. 1030-1037
    • Xu, R.H.1    He, J.F.2    Evans, M.R.3
  • 9
    • 10744228014 scopus 로고    scopus 로고
    • Epidemiology and cause of severe acute respiratory syndrome in Guangdong, People's Republic of China, in Feb 2003
    • 9 Zhong, N.S., Zheng, B.J., Li, Y.M., et al. Epidemiology and cause of severe acute respiratory syndrome in Guangdong, People's Republic of China, in Feb 2003. Lancet 362 (2003), 1353–1358.
    • (2003) Lancet , vol.362 , pp. 1353-1358
    • Zhong, N.S.1    Zheng, B.J.2    Li, Y.M.3
  • 10
    • 33644876694 scopus 로고    scopus 로고
    • Analysis on the characteristics of blood serum Ab-IgG detective result of severe acute respiratory syndrome patients in Guangzhou, China
    • 10 Du, L., Qiu, J.C., Wang, M., et al. Analysis on the characteristics of blood serum Ab-IgG detective result of severe acute respiratory syndrome patients in Guangzhou, China. Zhonghua Liu Xing Bing Xue Za Zhi 25 (2004), 925–928.
    • (2004) Zhonghua Liu Xing Bing Xue Za Zhi , vol.25 , pp. 925-928
    • Du, L.1    Qiu, J.C.2    Wang, M.3
  • 11
    • 0141889936 scopus 로고    scopus 로고
    • Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China
    • 11 Guan, Y., Zheng, B.J., He, Y.Q., et al. Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China. Science 302 (2003), 276–278.
    • (2003) Science , vol.302 , pp. 276-278
    • Guan, Y.1    Zheng, B.J.2    He, Y.Q.3
  • 12
    • 33644819689 scopus 로고    scopus 로고
    • SARS-CoV infection in a restaurant from palm civet
    • 12 Wang, M., Yan, M., Xu, H., et al. SARS-CoV infection in a restaurant from palm civet. Emerg Infect Dis 11 (2005), 1860–1865.
    • (2005) Emerg Infect Dis , vol.11 , pp. 1860-1865
    • Wang, M.1    Yan, M.2    Xu, H.3
  • 13
    • 20044382817 scopus 로고    scopus 로고
    • Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human
    • 13 Song, H.D., Tu, C.C., Zhang, G.W., et al. Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A 102 (2005), 2430–2435.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2430-2435
    • Song, H.D.1    Tu, C.C.2    Zhang, G.W.3
  • 14
    • 25444531712 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats
    • 14 Lau, S.K., Woo, P.C., Li, K.S., et al. Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats. Proc Natl Acad Sci 102 (2005), 14040–14045.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 14040-14045
    • Lau, S.K.1    Woo, P.C.2    Li, K.S.3
  • 15
    • 27344438916 scopus 로고    scopus 로고
    • Bats are natural reserviors of SARS-like coronaviruses
    • 15 Li, W., Shi, Z., Yu, M., et al. Bats are natural reserviors of SARS-like coronaviruses. Science 310 (2005), 676–679.
    • (2005) Science , vol.310 , pp. 676-679
    • Li, W.1    Shi, Z.2    Yu, M.3
  • 16
    • 40649112893 scopus 로고    scopus 로고
    • A review of studies on animal reservoirs of the SARS coronavirus
    • 16 Shi, Z., Hu, Z., A review of studies on animal reservoirs of the SARS coronavirus. Virus Res 133 (2008), 74–87.
    • (2008) Virus Res , vol.133 , pp. 74-87
    • Shi, Z.1    Hu, Z.2
  • 17
    • 3342993325 scopus 로고    scopus 로고
    • Persistent infection of SARS coronavirus in colonic cells in vitro
    • 17 Chan, P.K., To, K.F., Lo, A.W., et al. Persistent infection of SARS coronavirus in colonic cells in vitro. J Med Virol 74 (2004), 1–7.
    • (2004) J Med Virol , vol.74 , pp. 1-7
    • Chan, P.K.1    To, K.F.2    Lo, A.W.3
  • 18
    • 23844448345 scopus 로고    scopus 로고
    • Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry
    • 18 Simmons, G., Gosalia, D.N., Rennekamp, A.J., et al. Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry. Proc Natl Acad Sci 102 (2005), 11876–11881.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 11876-11881
    • Simmons, G.1    Gosalia, D.N.2    Rennekamp, A.J.3
  • 19
    • 0344395657 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
    • 19 Li, W., Moore, M.J., Vasilieva, N., et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 426 (2003), 450–454.
    • (2003) Nature , vol.426 , pp. 450-454
    • Li, W.1    Moore, M.J.2    Vasilieva, N.3
  • 20
    • 21844460785 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 protects from severe acute lung failure
    • 20 Imai, Y., Kuba, K., Rao, S., et al. Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature 436 (2005), 112–116.
    • (2005) Nature , vol.436 , pp. 112-116
    • Imai, Y.1    Kuba, K.2    Rao, S.3
  • 21
    • 21444437527 scopus 로고    scopus 로고
    • The 3a protein of severe acute respiratory syndrome-associated coronavirus induces apoptosis in Vero E6 cells
    • 21 Law, P.T., Wong, C.H., Au, T.C., et al. The 3a protein of severe acute respiratory syndrome-associated coronavirus induces apoptosis in Vero E6 cells. J Gen Virol 86 (2005), 1921–1930.
    • (2005) J Gen Virol , vol.86 , pp. 1921-1930
    • Law, P.T.1    Wong, C.H.2    Au, T.C.3
  • 22
    • 10044235725 scopus 로고    scopus 로고
    • Over expression of 7a, a protein specifically encoded by the severe acute respiratory syndrome coronavirus, induces apoptosis via a caspase-dependent pathway
    • 22 Tan, Y.J., Fielding, B.C., Goh, P.Y., et al. Over expression of 7a, a protein specifically encoded by the severe acute respiratory syndrome coronavirus, induces apoptosis via a caspase-dependent pathway. J Virol 78 (2004), 14043–14047.
    • (2004) J Virol , vol.78 , pp. 14043-14047
    • Tan, Y.J.1    Fielding, B.C.2    Goh, P.Y.3
  • 23
    • 0038024612 scopus 로고    scopus 로고
    • Lung pathology of fatal severe acute respiratory syndrome
    • 23 Nicholls, J.M., Poon, L.L., Lee, K.C., et al. Lung pathology of fatal severe acute respiratory syndrome. Lancet 361 (2003), 1773–1778.
    • (2003) Lancet , vol.361 , pp. 1773-1778
    • Nicholls, J.M.1    Poon, L.L.2    Lee, K.C.3
  • 24
    • 0038362701 scopus 로고    scopus 로고
    • Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study
    • 24 Peiris, J.S., Chu, C.M., Cheng, V.C., et al., HKU/UCH SARS Study Group. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet 361 (2003), 1767–1772.
    • (2003) Lancet , vol.361 , pp. 1767-1772
    • Peiris, J.S.1    Chu, C.M.2    Cheng, V.C.3
  • 25
    • 12144285615 scopus 로고    scopus 로고
    • Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome
    • 25 Wong, C.K., Lam, C.W.K., Wu, A.K., et al. Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome. Clin Exp Immunol 136 (2004), 95–103.
    • (2004) Clin Exp Immunol , vol.136 , pp. 95-103
    • Wong, C.K.1    Lam, C.W.K.2    Wu, A.K.3
  • 26
    • 77956038851 scopus 로고    scopus 로고
    • T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice
    • 26 Zhao, J., Zhao, J., Perlman, S., T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice. J Virol 84:18 (2010), 9318–9325.
    • (2010) J Virol , vol.84 , Issue.18 , pp. 9318-9325
    • Zhao, J.1    Zhao, J.2    Perlman, S.3
  • 27
    • 85012027074 scopus 로고    scopus 로고
    • Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice
    • 27 Channappanavar, R., Fehr, A.R., Vijay, R., et al. Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice. Cell Host Microbe 19:2 (2016), 181–193.
    • (2016) Cell Host Microbe , vol.19 , Issue.2 , pp. 181-193
    • Channappanavar, R.1    Fehr, A.R.2    Vijay, R.3
  • 28
    • 48249126829 scopus 로고    scopus 로고
    • IL-12 RB1 genetic variants contribute to human susceptibility to severe acute respiratory syndrome infection among Chinese
    • 28 Tang, F., Liu, W., Zhang, F., et al. IL-12 RB1 genetic variants contribute to human susceptibility to severe acute respiratory syndrome infection among Chinese. PLoS One, 3(5), 2008, e2183.
    • (2008) PLoS One , vol.3 , Issue.5 , pp. e2183
    • Tang, F.1    Liu, W.2    Zhang, F.3
  • 29
    • 20844452048 scopus 로고    scopus 로고
    • Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection
    • 29 Ip, W.K., Chan, K.H., Law, H.K., et al. Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection. J Infect Dis 191:10 (2005), 1697–1704.
    • (2005) J Infect Dis , vol.191 , Issue.10 , pp. 1697-1704
    • Ip, W.K.1    Chan, K.H.2    Law, H.K.3
  • 30
    • 0041386203 scopus 로고    scopus 로고
    • Lung pathology of severe acute respiratory syndrome (SARS): a study of 8 autopsy cases from Singapore
    • 30 Franks, T.J., Chong, P.Y., Chui, P., et al. Lung pathology of severe acute respiratory syndrome (SARS): a study of 8 autopsy cases from Singapore. Hum Pathol 34 (2003), 743–748.
    • (2003) Hum Pathol , vol.34 , pp. 743-748
    • Franks, T.J.1    Chong, P.Y.2    Chui, P.3
  • 31
    • 12144288187 scopus 로고    scopus 로고
    • Pulmonary pathological features in coronavirus associated severe acute respiratory syndrome (SARS)
    • 31 Tse, G.M., To, K.F., Chan, P.K., et al. Pulmonary pathological features in coronavirus associated severe acute respiratory syndrome (SARS). J Clin Pathol 57 (2004), 260–265.
    • (2004) J Clin Pathol , vol.57 , pp. 260-265
    • Tse, G.M.1    To, K.F.2    Chan, P.K.3
  • 32
    • 0037783502 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome in Singapore: clinical features of index patient and initial contacts
    • 32 Hsu, L.Y., Lee, C.C., Green, J.A., et al. Severe acute respiratory syndrome in Singapore: clinical features of index patient and initial contacts. Emerg Infect Dis 9 (2003), 713–717.
    • (2003) Emerg Infect Dis , vol.9 , pp. 713-717
    • Hsu, L.Y.1    Lee, C.C.2    Green, J.A.3
  • 33
    • 0037976821 scopus 로고    scopus 로고
    • Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area
    • 33 Booth, C.M., Matukas, L.M., Tomlinson, G.A., et al. Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area. JAMA 289 (2003), 2801–2809.
    • (2003) JAMA , vol.289 , pp. 2801-2809
    • Booth, C.M.1    Matukas, L.M.2    Tomlinson, G.A.3
  • 34
    • 85011025505 scopus 로고    scopus 로고
    • Summary of probable SARS cases with onset of illness from 1 November to 31 July. Available at: Accessed July 2, 2016.
    • 34 WHO. Summary of probable SARS cases with onset of illness from 1 November to 31 July 2003. Available at: http://www.who.int/csr/sars/country/table2004_04_21/en/. Accessed July 2, 2016.
    • (2003)
  • 35
    • 0346750858 scopus 로고    scopus 로고
    • The severe acute respiratory syndrome
    • 35 Peiris, J.S., Yuen, K.Y., Osterhaus, A.D., et al. The severe acute respiratory syndrome. N Engl J Med 349 (2003), 2431–2441.
    • (2003) N Engl J Med , vol.349 , pp. 2431-2441
    • Peiris, J.S.1    Yuen, K.Y.2    Osterhaus, A.D.3
  • 36
    • 0842347347 scopus 로고    scopus 로고
    • Index patient and SARS outbreak in Hong Kong
    • 36 Wong, R.S., Hui, D.S., Index patient and SARS outbreak in Hong Kong. Emerg Infect Dis 10 (2004), 339–341.
    • (2004) Emerg Infect Dis , vol.10 , pp. 339-341
    • Wong, R.S.1    Hui, D.S.2
  • 37
    • 17644397589 scopus 로고    scopus 로고
    • Temporal-spatial analysis of Severe acute respiratory syndrome among hospital inpatients
    • 37 Yu, I.T., Wong, T.W., Chiu, Y.L., et al. Temporal-spatial analysis of Severe acute respiratory syndrome among hospital inpatients. Clin Infect Dis 40 (2005), 1237–1243.
    • (2005) Clin Infect Dis , vol.40 , pp. 1237-1243
    • Yu, I.T.1    Wong, T.W.2    Chiu, Y.L.3
  • 38
    • 3042718313 scopus 로고    scopus 로고
    • The severe acute respiratory syndrome coronavirus in tears
    • 38 Loon, S.C., Teoh, S.C., Oon, L.L., et al. The severe acute respiratory syndrome coronavirus in tears. Br J Ophthalmol 88 (2004), 861–863.
    • (2004) Br J Ophthalmol , vol.88 , pp. 861-863
    • Loon, S.C.1    Teoh, S.C.2    Oon, L.L.3
  • 39
    • 1942467995 scopus 로고    scopus 로고
    • Evidence of airborne transmission of the severe acute respiratory syndrome virus
    • 39 Yu, I.T., Li, Y., Wong, T.W., et al. Evidence of airborne transmission of the severe acute respiratory syndrome virus. N Engl J Med 350 (2004), 1731–1739.
    • (2004) N Engl J Med , vol.350 , pp. 1731-1739
    • Yu, I.T.1    Li, Y.2    Wong, T.W.3
  • 40
    • 33644817673 scopus 로고    scopus 로고
    • Viral load distribution in SARS outbreak
    • 40 Chu, C.M., Cheng, V.C., Hung, I.F., et al. Viral load distribution in SARS outbreak. Emerg Infect Dis 11 (2005), 1882–1886.
    • (2005) Emerg Infect Dis , vol.11 , pp. 1882-1886
    • Chu, C.M.1    Cheng, V.C.2    Hung, I.F.3
  • 41
    • 84894233914 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome beyond Amoy Gardens: completing the incomplete legacy
    • 41 Yu, I.T., Qiu, H., Tse, L.A., et al. Severe acute respiratory syndrome beyond Amoy Gardens: completing the incomplete legacy. Clin Infect Dis 58:5 (2014), 683–686.
    • (2014) Clin Infect Dis , vol.58 , Issue.5 , pp. 683-686
    • Yu, I.T.1    Qiu, H.2    Tse, L.A.3
  • 42
    • 20244361957 scopus 로고    scopus 로고
    • Detection of airborne Severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units
    • 42 Booth, T.F., Kournikakis, B., Bastien, N., et al. Detection of airborne Severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units. J Infect Dis 191 (2005), 1472–1477.
    • (2005) J Infect Dis , vol.191 , pp. 1472-1477
    • Booth, T.F.1    Kournikakis, B.2    Bastien, N.3
  • 43
    • 3242687609 scopus 로고    scopus 로고
    • The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: an analysis of all 1755 patients
    • 43 Leung, G.M., Hedley, A.J., Ho, L.M., et al. The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: an analysis of all 1755 patients. Ann Intern Med 141 (2004), 662–673.
    • (2004) Ann Intern Med , vol.141 , pp. 662-673
    • Leung, G.M.1    Hedley, A.J.2    Ho, L.M.3
  • 44
    • 0242717589 scopus 로고    scopus 로고
    • Coronavirus as a possible cause of severe acute respiratory syndrome
    • 44 Peiris, J.S., Lai, S.T., Poon, L.L., et al. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet 361 (2003), 1319–1325.
    • (2003) Lancet , vol.361 , pp. 1319-1325
    • Peiris, J.S.1    Lai, S.T.2    Poon, L.L.3
  • 45
    • 0141483076 scopus 로고    scopus 로고
    • Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection
    • 45 Leung, W.K., To, K.F., Chan, P.K., et al. Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection. Gastroenterol 125 (2003), 1011–1017.
    • (2003) Gastroenterol , vol.125 , pp. 1011-1017
    • Leung, W.K.1    To, K.F.2    Chan, P.K.3
  • 46
    • 0344945638 scopus 로고    scopus 로고
    • Detection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndrome
    • 46 Hung, E.C., Chim, S.S., Chan, P.K., et al. Detection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndrome. Clin Chem 49 (2003), 2108–2109.
    • (2003) Clin Chem , vol.49 , pp. 2108-2109
    • Hung, E.C.1    Chim, S.S.2    Chan, P.K.3
  • 47
    • 0842325665 scopus 로고    scopus 로고
    • Possible central nervous system infection by SARS coronavirus
    • 47 Lau, K.K., Yu, W.C., Chu, C.M., et al. Possible central nervous system infection by SARS coronavirus. Emerg Infect Dis 10 (2004), 342–344.
    • (2004) Emerg Infect Dis , vol.10 , pp. 342-344
    • Lau, K.K.1    Yu, W.C.2    Chu, C.M.3
  • 48
    • 0038801260 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome (SARS) in a geriatric patient with a hip fracture. A case report
    • 48 Wong, K.C., Leung, K.S., Hui, M., Severe acute respiratory syndrome (SARS) in a geriatric patient with a hip fracture. A case report. J Bone Joint Surg Am 85A (2003), 1339–1342.
    • (2003) J Bone Joint Surg Am , vol.85A , pp. 1339-1342
    • Wong, K.C.1    Leung, K.S.2    Hui, M.3
  • 49
    • 0037648996 scopus 로고    scopus 로고
    • Clinical presentations and outcome of severe acute respiratory syndrome in children
    • 49 Hon, K.L., Leung, C.W., Cheng, W.T., et al. Clinical presentations and outcome of severe acute respiratory syndrome in children. Lancet 561 (2003), 1701–1703.
    • (2003) Lancet , vol.561 , pp. 1701-1703
    • Hon, K.L.1    Leung, C.W.2    Cheng, W.T.3
  • 50
    • 3042686631 scopus 로고    scopus 로고
    • Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome
    • 50 Wong, S.F., Chow, K.M., Leung, T.N., et al. Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome. Am J Obstet Gynecol 191 (2004), 292–297.
    • (2004) Am J Obstet Gynecol , vol.191 , pp. 292-297
    • Wong, S.F.1    Chow, K.M.2    Leung, T.N.3
  • 51
    • 33244460572 scopus 로고    scopus 로고
    • Seroprevalence of IgG antibodies to SARS-coronavirus in asymptomatic or subclinical population groups
    • 51 Leung, G.M., Lim, W.W., Ho, L.M., et al. Seroprevalence of IgG antibodies to SARS-coronavirus in asymptomatic or subclinical population groups. Epidemiol Infect 134 (2006), 211–221.
    • (2006) Epidemiol Infect , vol.134 , pp. 211-221
    • Leung, G.M.1    Lim, W.W.2    Ho, L.M.3
  • 52
    • 7044220706 scopus 로고    scopus 로고
    • Severe Acute Respiratory Syndrome (SARS): correlation of clinical outcome and radiological features
    • 52 Hui, D.S., Wong, K.T., Antonio, G.E., et al. Severe Acute Respiratory Syndrome (SARS): correlation of clinical outcome and radiological features. Radiology 233 (2004), 579–585.
    • (2004) Radiology , vol.233 , pp. 579-585
    • Hui, D.S.1    Wong, K.T.2    Antonio, G.E.3
  • 53
    • 0346993137 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome: clinical features and diagnosis
    • 53 Hui, D.S., Wong, P.C., Wang, C., Severe acute respiratory syndrome: clinical features and diagnosis. Respirol 8 (2003), S20–S24.
    • (2003) Respirol , vol.8 , pp. S20-S24
    • Hui, D.S.1    Wong, P.C.2    Wang, C.3
  • 54
    • 0037899009 scopus 로고    scopus 로고
    • Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis
    • 54 Wong, R.S., Wu, A., To, K.F., et al. Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis. Br Med J 326 (2003), 1358–1362.
    • (2003) Br Med J , vol.326 , pp. 1358-1362
    • Wong, R.S.1    Wu, A.2    To, K.F.3
  • 55
    • 0037727352 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome: radiographic appearances and pattern of progression in 138 patients
    • 55 Wong, K.T., Antonio, G.E., Hui, D.S., et al. Severe acute respiratory syndrome: radiographic appearances and pattern of progression in 138 patients. Radiology 228 (2003), 401–406.
    • (2003) Radiology , vol.228 , pp. 401-406
    • Wong, K.T.1    Antonio, G.E.2    Hui, D.S.3
  • 56
    • 18344419173 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome-related coronavirus is inhibited by interferon-α
    • 56 Stroher, U., DiCaro, A., Li, Y., et al. Severe acute respiratory syndrome-related coronavirus is inhibited by interferon-α. J Infect Dis 189 (2004), 1164–1167.
    • (2004) J Infect Dis , vol.189 , pp. 1164-1167
    • Stroher, U.1    DiCaro, A.2    Li, Y.3
  • 57
    • 12144290587 scopus 로고    scopus 로고
    • Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings
    • 57 Chu, C.M., Cheng, V.C., Hung, I.F., et al. Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings. Thorax 59 (2004), 252–256.
    • (2004) Thorax , vol.59 , pp. 252-256
    • Chu, C.M.1    Cheng, V.C.2    Hung, I.F.3
  • 58
    • 10744223243 scopus 로고    scopus 로고
    • Treatment of severe acute respiratory syndrome with lopinavir/ritonavir: a multicenter retrospective matched cohort study
    • 58 Chan, K.S., Lai, S.T., Chu, C.M., et al. Treatment of severe acute respiratory syndrome with lopinavir/ritonavir: a multicenter retrospective matched cohort study. Hong Kong Med J 9 (2003), 399–406.
    • (2003) Hong Kong Med J , vol.9 , pp. 399-406
    • Chan, K.S.1    Lai, S.T.2    Chu, C.M.3
  • 59
    • 0043200981 scopus 로고    scopus 로고
    • Treatment of SARS with human interferons
    • 59 Cinatl, J., Morgenstern, B., Bauer, G., et al. Treatment of SARS with human interferons. Lancet 362 (2003), 293–294.
    • (2003) Lancet , vol.362 , pp. 293-294
    • Cinatl, J.1    Morgenstern, B.2    Bauer, G.3
  • 60
    • 0842325670 scopus 로고    scopus 로고
    • Interferon-β 1a and SARS coronavirus replication
    • 60 Hensley, L.E., Fritz, L.E., Jahrling, P.B., et al. Interferon-β 1a and SARS coronavirus replication. Emerg Infect Dis 10 (2004), 317–319.
    • (2004) Emerg Infect Dis , vol.10 , pp. 317-319
    • Hensley, L.E.1    Fritz, L.E.2    Jahrling, P.B.3
  • 61
    • 2342645538 scopus 로고    scopus 로고
    • Pegylated interferon-α protects type 1 pneumocytes against SARS coronavirus infection in macaques
    • 61 Haagmans, B.L., Kuiken, T., Martina, B.E., et al. Pegylated interferon-α protects type 1 pneumocytes against SARS coronavirus infection in macaques. Nat Med 10 (2004), 290–293.
    • (2004) Nat Med , vol.10 , pp. 290-293
    • Haagmans, B.L.1    Kuiken, T.2    Martina, B.E.3
  • 62
    • 0348136783 scopus 로고    scopus 로고
    • Interferon Alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study
    • 62 Loutfy, M.R., Blatt, L.M., Siminovitch, K.A., et al. Interferon Alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study. JAMA 290 (2003), 3222–3228.
    • (2003) JAMA , vol.290 , pp. 3222-3228
    • Loutfy, M.R.1    Blatt, L.M.2    Siminovitch, K.A.3
  • 63
    • 20244373630 scopus 로고    scopus 로고
    • Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome
    • 63 Jiang, Y., Xu, J., Zhou, C., et al. Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome. Am J Respir Crit Care Med 171 (2005), 850–857.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 850-857
    • Jiang, Y.1    Xu, J.2    Zhou, C.3
  • 64
    • 2442581595 scopus 로고    scopus 로고
    • Severe Acute Respiratory Syndrome: report of treatment and outcome after a major outbreak
    • 64 Sung, J.J., Wu, A., Joynt, G.M., et al. Severe Acute Respiratory Syndrome: report of treatment and outcome after a major outbreak. Thorax 59 (2004), 414–420.
    • (2004) Thorax , vol.59 , pp. 414-420
    • Sung, J.J.1    Wu, A.2    Joynt, G.M.3
  • 65
    • 10744233001 scopus 로고    scopus 로고
    • Coronavirus-positive nasopharyngeal aspirate as predictor for severe acute respiratory syndrome mortality
    • 65 Tsang, O.T., Chau, T.N., Choi, K.W., et al. Coronavirus-positive nasopharyngeal aspirate as predictor for severe acute respiratory syndrome mortality. Emerg Infect Dis 9 (2003), 1381–1387.
    • (2003) Emerg Infect Dis , vol.9 , pp. 1381-1387
    • Tsang, O.T.1    Chau, T.N.2    Choi, K.W.3
  • 66
    • 0042844713 scopus 로고    scopus 로고
    • Fatal aspergillosis in a patient with SARS who was treated with corticosteroids
    • 66 Wang, H., Ding, Y., Li, X., et al. Fatal aspergillosis in a patient with SARS who was treated with corticosteroids. N Engl J Med 349 (2003), 507–508.
    • (2003) N Engl J Med , vol.349 , pp. 507-508
    • Wang, H.1    Ding, Y.2    Li, X.3
  • 67
    • 20144388654 scopus 로고    scopus 로고
    • Osteonecrosis of hip and knee in patients with severe acute respiratory syndrome treated with steroids
    • 67 Griffith, J.F., Antonio, G.E., Kumta, S.M., et al. Osteonecrosis of hip and knee in patients with severe acute respiratory syndrome treated with steroids. Radiology 235 (2005), 168–175.
    • (2005) Radiology , vol.235 , pp. 168-175
    • Griffith, J.F.1    Antonio, G.E.2    Kumta, S.M.3
  • 68
    • 5644261635 scopus 로고    scopus 로고
    • Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients
    • 68 Lee, N., Allen Chan, K.C., Hui, D.S., et al. Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients. J Clin Virol 31 (2004), 304–309.
    • (2004) J Clin Virol , vol.31 , pp. 304-309
    • Lee, N.1    Allen Chan, K.C.2    Hui, D.S.3
  • 69
    • 4043134495 scopus 로고    scopus 로고
    • Retrospective comparison of convalescent plasma with continuing high-dose methylprednisolone treatment in SARS patients
    • 69 Soo, Y., Cheng, Y., Wong, R., et al. Retrospective comparison of convalescent plasma with continuing high-dose methylprednisolone treatment in SARS patients. Clin Microbiol Infect 10 (2004), 676–678.
    • (2004) Clin Microbiol Infect , vol.10 , pp. 676-678
    • Soo, Y.1    Cheng, Y.2    Wong, R.3
  • 70
    • 19944433718 scopus 로고    scopus 로고
    • Use of convalescent plasma therapy in SARS patients in Hong Kong
    • 70 Cheng, Y., Wong, R., Soo, Y.O., et al. Use of convalescent plasma therapy in SARS patients in Hong Kong. Eur J Clin Microbiol Infect Dis 24 (2005), 44–46.
    • (2005) Eur J Clin Microbiol Infect Dis , vol.24 , pp. 44-46
    • Cheng, Y.1    Wong, R.2    Soo, Y.O.3
  • 71
    • 84922440585 scopus 로고    scopus 로고
    • The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysis
    • 71 Mair-Jenkins, J., Saavedra-Campos, M., Baillie, J.K., et al., Convalescent Plasma Study Group. The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysis. J Infect Dis 211 (2015), 80–90.
    • (2015) J Infect Dis , vol.211 , pp. 80-90
    • Mair-Jenkins, J.1    Saavedra-Campos, M.2    Baillie, J.K.3
  • 72
    • 33947541796 scopus 로고    scopus 로고
    • Why did outbreaks of severe acute respiratory syndrome occur in some hospital wards but not in others?
    • 72 Yu, I.T., Xie, Z.H., Tsoi, K.K., et al. Why did outbreaks of severe acute respiratory syndrome occur in some hospital wards but not in others?. Clin Infect Dis 44 (2007), 1017–1025.
    • (2007) Clin Infect Dis , vol.44 , pp. 1017-1025
    • Yu, I.T.1    Xie, Z.H.2    Tsoi, K.K.3
  • 73
    • 84860369361 scopus 로고    scopus 로고
    • Aerosol generating procedures and risk of transmission of acute respiratory infections to healthcare workers: a systematic review
    • 73 Tran, K., Cimon, K., Severn, M., et al. Aerosol generating procedures and risk of transmission of acute respiratory infections to healthcare workers: a systematic review. PLoS One, 7, 2012, e35797.
    • (2012) PLoS One , vol.7 , pp. e35797
    • Tran, K.1    Cimon, K.2    Severn, M.3
  • 74
    • 84868516062 scopus 로고    scopus 로고
    • Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia
    • 74 Zaki, A.M., van Boheemen, S., Bestebroer, T.M., et al. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med 367 (2012), 1814–1820.
    • (2012) N Engl J Med , vol.367 , pp. 1814-1820
    • Zaki, A.M.1    van Boheemen, S.2    Bestebroer, T.M.3
  • 75
    • 84963872013 scopus 로고    scopus 로고
    • Middle East Respiratory Syndrome Coronavirus (MERS-CoV) – Qatar
    • Available at: Accessed July 2, 2016
    • 75 World Health Organization, Middle East Respiratory Syndrome Coronavirus (MERS-CoV) – Qatar. Disease Outbreak News, 2016 Available at: http://www.who.int/csr/don/29-june-2016-mers-qatar/en/ Accessed July 2, 2016.
    • (2016) Disease Outbreak News
    • World Health Organization1
  • 76
    • 85011033792 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus case definition for reporting to WHO interim case definition 14 July. Available at: Accessed July 2, 2016.
    • 76 WHO. Middle East respiratory syndrome coronavirus case definition for reporting to WHO interim case definition 14 July 2015. Available at: http://www.who.int/csr/disease/coronavirus_infections/case_definition/en/. Accessed July 2, 2016.
    • (2015)
  • 77
    • 84874096089 scopus 로고    scopus 로고
    • Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe
    • 77 Annan, A., Baldwin, H.J., Corman, V.M., et al. Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe. Emerg Infect Dis 19 (2013), 456–459.
    • (2013) Emerg Infect Dis , vol.19 , pp. 456-459
    • Annan, A.1    Baldwin, H.J.2    Corman, V.M.3
  • 78
    • 84884233679 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus in bats, Saudi Arabia
    • 78 Memish, Z.A., Mishra, N., Olival, K.J., et al. Middle East respiratory syndrome coronavirus in bats, Saudi Arabia. Emerg Infect Dis 19 (2013), 1819–1823.
    • (2013) Emerg Infect Dis , vol.19 , pp. 1819-1823
    • Memish, Z.A.1    Mishra, N.2    Olival, K.J.3
  • 79
    • 84958787001 scopus 로고    scopus 로고
    • Absence of Middle East respiratory syndrome coronavirus in Camelids, Kazakhstan, 2015
    • 79 Miguel, E., Perera, R.A., Baubekova, A., et al. Absence of Middle East respiratory syndrome coronavirus in Camelids, Kazakhstan, 2015. Emerg Infect Dis 22:3 (2016), 555–557.
    • (2016) Emerg Infect Dis , vol.22 , Issue.3 , pp. 555-557
    • Miguel, E.1    Perera, R.A.2    Baubekova, A.3
  • 80
    • 84931360037 scopus 로고    scopus 로고
    • Absence of MERS-coronavirus in bactrian camels, southern Mongolia, November 2014
    • 80 Chan, S.M., Damdinjav, B., Perera, R.A., et al. Absence of MERS-coronavirus in bactrian camels, southern Mongolia, November 2014. Emerg Infect Dis 21:7 (2015), 1269–1271.
    • (2015) Emerg Infect Dis , vol.21 , Issue.7 , pp. 1269-1271
    • Chan, S.M.1    Damdinjav, B.2    Perera, R.A.3
  • 81
    • 84902239619 scopus 로고    scopus 로고
    • Seroepidemiology of Middle East Respiratory Syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity
    • pii: 20828
    • 81 Hemida, M.G., Perera, R.A., Al Jassim, R.A., et al. Seroepidemiology of Middle East Respiratory Syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity. Euro Surveill, 19(23), 2014 pii: 20828.
    • (2014) Euro Surveill , vol.19 , Issue.23
    • Hemida, M.G.1    Perera, R.A.2    Al Jassim, R.A.3
  • 82
    • 84939451094 scopus 로고    scopus 로고
    • Dromedary camels and the transmission of Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
    • 82 Hemida, M.G., Elmoslemany, A., Al-Hizab, F., et al. Dromedary camels and the transmission of Middle East Respiratory Syndrome Coronavirus (MERS-CoV). Transbound Emerg Dis, 2015, 10.1111/tbed.12401.
    • (2015) Transbound Emerg Dis
    • Hemida, M.G.1    Elmoslemany, A.2    Al-Hizab, F.3
  • 83
    • 84916891516 scopus 로고    scopus 로고
    • Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: a single-center experience in Saudi Arabia
    • 83 Saad, M., Omrani, A.S., Baig, K., et al. Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: a single-center experience in Saudi Arabia. Int J Infect Dis 29 (2014), 301–306.
    • (2014) Int J Infect Dis , vol.29 , pp. 301-306
    • Saad, M.1    Omrani, A.S.2    Baig, K.3
  • 84
    • 84940313968 scopus 로고    scopus 로고
    • Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation
    • 84 Hijawi, B., Abdallat, M., Sayaydeh, A., et al. Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation. East Mediterr Health J 19:Suppl 1 (2013), S12–S18.
    • (2013) East Mediterr Health J , vol.19 , pp. S12-S18
    • Hijawi, B.1    Abdallat, M.2    Sayaydeh, A.3
  • 85
    • 84950291086 scopus 로고    scopus 로고
    • Risk factors for primary Middle East respiratory syndrome coronavirus illness in humans, Saudi Arabia, 2014
    • 85 Alraddadi, B.M., Watson, J.T., Almarashi, A., et al. Risk factors for primary Middle East respiratory syndrome coronavirus illness in humans, Saudi Arabia, 2014. Emerg Infect Dis 22:1 (2016), 49–55.
    • (2016) Emerg Infect Dis , vol.22 , Issue.1 , pp. 49-55
    • Alraddadi, B.M.1    Watson, J.T.2    Almarashi, A.3
  • 86
    • 84907331317 scopus 로고    scopus 로고
    • Transmission of MERS-coronavirus in household contacts
    • 86 Drosten, C., Meyer, B., Müller, M.A., et al. Transmission of MERS-coronavirus in household contacts. N Engl J Med 371:9 (2014), 828–835.
    • (2014) N Engl J Med , vol.371 , Issue.9 , pp. 828-835
    • Drosten, C.1    Meyer, B.2    Müller, M.A.3
  • 87
    • 84978639838 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus transmission in extended family, Saudi Arabia, 2014
    • 87 Arwady, M.A., Alraddadi, B., Basler, C., et al. Middle East respiratory syndrome coronavirus transmission in extended family, Saudi Arabia, 2014. Emerg Infect Dis 22:8 (2016), 1395–1402.
    • (2016) Emerg Infect Dis , vol.22 , Issue.8 , pp. 1395-1402
    • Arwady, M.A.1    Alraddadi, B.2    Basler, C.3
  • 88
    • 84928213277 scopus 로고    scopus 로고
    • Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study
    • 88 Müller, M.A., Meyer, B., Corman, V.M., et al. Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study. Lancet Infect Dis 15:5 (2015), 559–564.
    • (2015) Lancet Infect Dis , vol.15 , Issue.5 , pp. 559-564
    • Müller, M.A.1    Meyer, B.2    Corman, V.M.3
  • 89
    • 84880088201 scopus 로고    scopus 로고
    • Hospital outbreak of Middle East respiratory syndrome coronavirus
    • 89 Assiri, A., McGeer, A., Perl, T.M., et al. Hospital outbreak of Middle East respiratory syndrome coronavirus. N Engl J Med 369 (2013), 407–416.
    • (2013) N Engl J Med , vol.369 , pp. 407-416
    • Assiri, A.1    McGeer, A.2    Perl, T.M.3
  • 90
    • 84923796636 scopus 로고    scopus 로고
    • 2014 MERS-CoV outbreak in Jeddah–a link to health care facilities
    • 90 Oboho, I.K., Tomczyk, S.M., Al-Asmari, A.M., et al. 2014 MERS-CoV outbreak in Jeddah–a link to health care facilities. N Engl J Med 372 (2015), 846–854.
    • (2015) N Engl J Med , vol.372 , pp. 846-854
    • Oboho, I.K.1    Tomczyk, S.M.2    Al-Asmari, A.M.3
  • 91
    • 84961210719 scopus 로고    scopus 로고
    • Transmission of Middle East respiratory syndrome coronavirus infections in healthcare settings, Abu Dhabi
    • 91 Hunter, J.C., Nguyen, D., Aden, B., et al. Transmission of Middle East respiratory syndrome coronavirus infections in healthcare settings, Abu Dhabi. Emerg Infect Dis 22 (2016), 647–656.
    • (2016) Emerg Infect Dis , vol.22 , pp. 647-656
    • Hunter, J.C.1    Nguyen, D.2    Aden, B.3
  • 92
    • 84942198680 scopus 로고    scopus 로고
    • Middle east respiratory syndrome coronavirus outbreak in the Republic of Korea, 2015
    • 92 Korea Centers for Disease Control and Prevention, Middle east respiratory syndrome coronavirus outbreak in the Republic of Korea, 2015. Osong Public Health Res Perspect 6:4 (2015), 269–278.
    • (2015) Osong Public Health Res Perspect , vol.6 , Issue.4 , pp. 269-278
    • Korea Centers for Disease Control and Prevention1
  • 93
    • 84946209567 scopus 로고    scopus 로고
    • Middle east respiratory sayndrome coronavirus superspreading event involving 81 persons, Korea 2015
    • 93 Oh, M.D., Choe, P.G., Oh, H.S., et al. Middle east respiratory sayndrome coronavirus superspreading event involving 81 persons, Korea 2015. J Korean Med Sci 30:11 (2015), 1701–1705.
    • (2015) J Korean Med Sci , vol.30 , Issue.11 , pp. 1701-1705
    • Oh, M.D.1    Choe, P.G.2    Oh, H.S.3
  • 94
    • 85011101767 scopus 로고    scopus 로고
    • WHO recommends continuation of strong disease control measures to bring MERS-CoV outbreak in Republic of Korea to an end. News Release 13 June. Available at: Accessed June 14, 2015.
    • 94 WHO. WHO recommends continuation of strong disease control measures to bring MERS-CoV outbreak in Republic of Korea to an end. News Release 13 June 2013. Available at: http://www.wpro.who.int/mediacentre/releases/2015/20150613/en/. Accessed June 14, 2015.
    • (2013)
  • 95
    • 84901832669 scopus 로고    scopus 로고
    • Infection control and MERS-CoV in health-care workers
    • 95 Zumla, A., Hui, D.S., Infection control and MERS-CoV in health-care workers. Lancet 383:9932 (2014), 1869–1871.
    • (2014) Lancet , vol.383 , Issue.9932 , pp. 1869-1871
    • Zumla, A.1    Hui, D.S.2
  • 96
    • 84971623891 scopus 로고    scopus 로고
    • State of knowledge and data gaps of Middle East respiratory syndrome coronavirus (MERS-CoV) in humans
    • pii: ecurrents.outbreaks.0bf719e352e7478f8ad85fa30127ddb8
    • 96 WHO MERS-CoV Research Group. State of knowledge and data gaps of Middle East respiratory syndrome coronavirus (MERS-CoV) in humans. PLoS Curr, 5, 2013 pii: ecurrents.outbreaks.0bf719e352e7478f8ad85fa30127ddb8.
    • (2013) PLoS Curr , vol.5
  • 97
    • 84882598788 scopus 로고    scopus 로고
    • Epidemiological, demographic, and clinical characteristics of 47 cases of middle east respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study
    • 97 Assiri, A., Al-Tawfiq, J.A., Al-Rabeeah, A.A., et al. Epidemiological, demographic, and clinical characteristics of 47 cases of middle east respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect Dis 13 (2013), 752–761.
    • (2013) Lancet Infect Dis , vol.13 , pp. 752-761
    • Assiri, A.1    Al-Tawfiq, J.A.2    Al-Rabeeah, A.A.3
  • 98
    • 84880053841 scopus 로고    scopus 로고
    • Clinical features and viral diagnosis of two cases of infection with middle east respiratory syndrome coronavirus: a report of nosocomial transmission
    • 98 Guery, B., Poissy, J., el Mansouf, L., et al. Clinical features and viral diagnosis of two cases of infection with middle east respiratory syndrome coronavirus: a report of nosocomial transmission. Lancet 381 (2013), 2265–2272.
    • (2013) Lancet , vol.381 , pp. 2265-2272
    • Guery, B.1    Poissy, J.2    el Mansouf, L.3
  • 99
    • 84879055980 scopus 로고    scopus 로고
    • Family cluster of middle east respiratory syndrome coronavirus infections
    • 99 Memish, Z.A., Zumla, A.I., Al-Hakeem, R.F., et al. Family cluster of middle east respiratory syndrome coronavirus infections. N Engl J Med 368 (2013), 2487–2494.
    • (2013) N Engl J Med , vol.368 , pp. 2487-2494
    • Memish, Z.A.1    Zumla, A.I.2    Al-Hakeem, R.F.3
  • 100
    • 85011107527 scopus 로고    scopus 로고
    • Neurological complications of middle east respiratory syndrome coronavirus: a report of two cases and review of the literature
    • 100 Algahtani, H., Subahi, A., Shirah, B., Neurological complications of middle east respiratory syndrome coronavirus: a report of two cases and review of the literature. Case Rep Neurol Med, 2016, 2016, 3502683.
    • (2016) Case Rep Neurol Med , vol.2016 , pp. 3502683
    • Algahtani, H.1    Subahi, A.2    Shirah, B.3
  • 101
    • 84990924183 scopus 로고    scopus 로고
    • Middle east respiratory syndrome coronavirus infection during pregnancy: a report of 5 cases from Saudi Arabia
    • 101 Assiri, A., Abedi, G.R., Almasry, M., et al. Middle east respiratory syndrome coronavirus infection during pregnancy: a report of 5 cases from Saudi Arabia. Clin Infect Dis 63:7 (2016), 951–953.
    • (2016) Clin Infect Dis , vol.63 , Issue.7 , pp. 951-953
    • Assiri, A.1    Abedi, G.R.2    Almasry, M.3
  • 102
    • 84959301270 scopus 로고    scopus 로고
    • Impact of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) on pregnancy and perinatal outcome
    • 102 Alserehi, H., Wali, G., Alshukairi, A., et al. Impact of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) on pregnancy and perinatal outcome. BMC Infect Dis, 16, 2016, 105.
    • (2016) BMC Infect Dis , vol.16 , pp. 105
    • Alserehi, H.1    Wali, G.2    Alshukairi, A.3
  • 103
    • 84958757526 scopus 로고    scopus 로고
    • Middle east respiratory syndrome- coronavirus during pregnancy, Abu Dhabi, United Arab Emirates, 2013
    • 103 Malik, A., El Masry, K.M., Ravi, M., et al. Middle east respiratory syndrome- coronavirus during pregnancy, Abu Dhabi, United Arab Emirates, 2013. Emerg Infect Dis 22:3 (2016), 515–517.
    • (2016) Emerg Infect Dis , vol.22 , Issue.3 , pp. 515-517
    • Malik, A.1    El Masry, K.M.2    Ravi, M.3
  • 104
    • 84899886613 scopus 로고    scopus 로고
    • Stillbirth during infection with Middle East respiratory syndrome coronavirus
    • 104 Payne, D.C., Iblan, I., Alqasrawi, S., et al. Stillbirth during infection with Middle East respiratory syndrome coronavirus. J Infect Dis 209:12 (2014), 1870–1872.
    • (2014) J Infect Dis , vol.209 , Issue.12 , pp. 1870-1872
    • Payne, D.C.1    Iblan, I.2    Alqasrawi, S.3
  • 105
    • 84882614929 scopus 로고    scopus 로고
    • Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection
    • 105 Drosten, C., Seilmaier, M., Corman, V.M., et al. Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection. Lancet Infect Dis 13 (2013), 745–751.
    • (2013) Lancet Infect Dis , vol.13 , pp. 745-751
    • Drosten, C.1    Seilmaier, M.2    Corman, V.M.3
  • 106
    • 84959859547 scopus 로고    scopus 로고
    • Viral shedding and antibody response in 37 patients with Middle East respiratory syndrome coronavirus infection
    • 106 Corman, V.M., Albarrak, A.M., Omrani, A.S., et al. Viral shedding and antibody response in 37 patients with Middle East respiratory syndrome coronavirus infection. Clin Infect Dis 62:4 (2016), 477–483.
    • (2016) Clin Infect Dis , vol.62 , Issue.4 , pp. 477-483
    • Corman, V.M.1    Albarrak, A.M.2    Omrani, A.S.3
  • 107
    • 84910134528 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus (MERS-CoV) infection: chest CT findings
    • 107 Ajlan, A.M., Ahyad, R.A., Jamjoom, L.G., et al. Middle East respiratory syndrome coronavirus (MERS-CoV) infection: chest CT findings. AJR Am J Roentgenol 203:4 (2014), 782–787.
    • (2014) AJR Am J Roentgenol , vol.203 , Issue.4 , pp. 782-787
    • Ajlan, A.M.1    Ahyad, R.A.2    Jamjoom, L.G.3
  • 108
    • 84874996988 scopus 로고    scopus 로고
    • Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
    • 108 Raj, V.S., Mou, H., Smits, S.L., et al. Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature 495 (2013), 251–254.
    • (2013) Nature , vol.495 , pp. 251-254
    • Raj, V.S.1    Mou, H.2    Smits, S.L.3
  • 109
    • 84881479703 scopus 로고    scopus 로고
    • Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
    • 109 Lu, G., Hu, Y., Wang, Q., et al. Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature 500 (2013), 227–231.
    • (2013) Nature , vol.500 , pp. 227-231
    • Lu, G.1    Hu, Y.2    Wang, Q.3
  • 110
    • 84872146295 scopus 로고    scopus 로고
    • Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines
    • pii: e00515–12
    • 110 Müller, M.A., Raj, V.S., Muth, D., et al. Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines. MBio, 3(6), 2012 pii: e00515–12.
    • (2012) MBio , vol.3 , Issue.6
    • Müller, M.A.1    Raj, V.S.2    Muth, D.3
  • 111
    • 84877262971 scopus 로고    scopus 로고
    • Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications for disease pathogenesis and clinical manifestation
    • 111 Chan, J.F., Chan, K.H., Choi, G.K., et al. Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications for disease pathogenesis and clinical manifestation. J Infect Dis 207 (2013), 1743–1752.
    • (2013) J Infect Dis , vol.207 , pp. 1743-1752
    • Chan, J.F.1    Chan, K.H.2    Choi, G.K.3
  • 112
    • 84880177352 scopus 로고    scopus 로고
    • MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment
    • 112 de Wilde, A.H., Raj, V.S., Oudshoorn, D., et al. MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment. J Gen Virol 94 (2013), 1749–1760.
    • (2013) J Gen Virol , vol.94 , pp. 1749-1760
    • de Wilde, A.H.1    Raj, V.S.2    Oudshoorn, D.3
  • 113
    • 84879840922 scopus 로고    scopus 로고
    • Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin
    • 113 Falzarano, D., de Wit, E., Martellaro, C., et al. Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin. Sci Rep, 3, 2013, 1686.
    • (2013) Sci Rep , vol.3 , pp. 1686
    • Falzarano, D.1    de Wit, E.2    Martellaro, C.3
  • 114
    • 84878523342 scopus 로고    scopus 로고
    • Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures
    • 114 Chan, R.W., Chan, M.C., Agnihothram, S., et al. Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures. J Virol 87 (2013), 6604–6614.
    • (2013) J Virol , vol.87 , pp. 6604-6614
    • Chan, R.W.1    Chan, M.C.2    Agnihothram, S.3
  • 115
    • 84886258554 scopus 로고    scopus 로고
    • Emerging human middle east respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs
    • 115 Hocke, A.C., Becher, A., Knepper, J., et al. Emerging human middle east respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs. Am J Respir Crit Care Med 188:7 (2013), 882–886.
    • (2013) Am J Respir Crit Care Med , vol.188 , Issue.7 , pp. 882-886
    • Hocke, A.C.1    Becher, A.2    Knepper, J.3
  • 116
    • 84895823870 scopus 로고    scopus 로고
    • Distinct immune response in two MERS-CoV-infected patients: can we go from bench to bedside?
    • 116 Faure, E., Poissy, J., Goffard, A., et al. Distinct immune response in two MERS-CoV-infected patients: can we go from bench to bedside?. PLoS One, 9(2), 2014, e88716.
    • (2014) PLoS One , vol.9 , Issue.2 , pp. e88716
    • Faure, E.1    Poissy, J.2    Goffard, A.3
  • 117
    • 84924021563 scopus 로고    scopus 로고
    • Kinetics and pattern of viral excretion in biological specimens of two MERS-CoV cases
    • 117 Poissy, J., Goffard, A., Parmentier-Decrucq, E., et al. Kinetics and pattern of viral excretion in biological specimens of two MERS-CoV cases. J Clin Virol 61:2 (2014), 275–278.
    • (2014) J Clin Virol , vol.61 , Issue.2 , pp. 275-278
    • Poissy, J.1    Goffard, A.2    Parmentier-Decrucq, E.3
  • 118
    • 84944561083 scopus 로고    scopus 로고
    • Kinetics of serologic responses to MERS coronavirus infection in humans, South Korea
    • 118 Park, W.B., Perera, R.A., Choe, P.G., et al. Kinetics of serologic responses to MERS coronavirus infection in humans, South Korea. Emerg Infect Dis 21:12 (2015), 2186–2189.
    • (2015) Emerg Infect Dis , vol.21 , Issue.12 , pp. 2186-2189
    • Park, W.B.1    Perera, R.A.2    Choe, P.G.3
  • 119
    • 84988528106 scopus 로고    scopus 로고
    • Persistence of antibodies against middle east respiratory syndrome coronavirus
    • 119 Payne, D.C., Iblan, I., Rha, B., et al. Persistence of antibodies against middle east respiratory syndrome coronavirus. Emerg Infect Dis 22:10 (2016), 1824–1826.
    • (2016) Emerg Infect Dis , vol.22 , Issue.10 , pp. 1824-1826
    • Payne, D.C.1    Iblan, I.2    Rha, B.3
  • 120
    • 84958935377 scopus 로고    scopus 로고
    • Clinicopathologic, immunohistochemical, and ultrastructural findings of a fatal case of middle east respiratory syndrome coronavirus infection in the United Arab Emirates, April 2014
    • 120 Ng, D.L., Al Hosani, F., Keating, M.K., et al. Clinicopathologic, immunohistochemical, and ultrastructural findings of a fatal case of middle east respiratory syndrome coronavirus infection in the United Arab Emirates, April 2014. Am J Pathol 186:3 (2016), 652–658.
    • (2016) Am J Pathol , vol.186 , Issue.3 , pp. 652-658
    • Ng, D.L.1    Al Hosani, F.2    Keating, M.K.3
  • 121
    • 84961911785 scopus 로고    scopus 로고
    • A case report of a Middle East respiratory syndrome survivor with kidney biopsy results
    • 121 Cha, R.H., Yang, S.H., Moon, K.C., et al. A case report of a Middle East respiratory syndrome survivor with kidney biopsy results. J Korean Med Sci 31:4 (2016), 635–640.
    • (2016) J Korean Med Sci , vol.31 , Issue.4 , pp. 635-640
    • Cha, R.H.1    Yang, S.H.2    Moon, K.C.3
  • 122
    • 84898850857 scopus 로고    scopus 로고
    • Active replication of middle east respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis
    • 122 Zhou, J., Chu, H., Li, C., et al. Active replication of middle east respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis. J Infect Dis 209:9 (2014), 1331–1342.
    • (2014) J Infect Dis , vol.209 , Issue.9 , pp. 1331-1342
    • Zhou, J.1    Chu, H.2    Li, C.3
  • 123
    • 84902176510 scopus 로고    scopus 로고
    • Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection
    • 123 Dyall, J., Coleman, C.M., Hart, B.J., et al. Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection. Antimicrob Agents Chemother 58:8 (2014), 4885–4893.
    • (2014) Antimicrob Agents Chemother , vol.58 , Issue.8 , pp. 4885-4893
    • Dyall, J.1    Coleman, C.M.2    Hart, B.J.3
  • 124
    • 84905386648 scopus 로고    scopus 로고
    • Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture
    • 124 De Wilde, A.H., Jochmans, D., Posthuma, C.C., et al. Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture. Antimicrob Agents Chemother 58:8 (2014), 4875–4884.
    • (2014) Antimicrob Agents Chemother , vol.58 , Issue.8 , pp. 4875-4884
    • De Wilde, A.H.1    Jochmans, D.2    Posthuma, C.C.3
  • 125
    • 84887492222 scopus 로고    scopus 로고
    • Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques
    • 125 Falzarano, D., de Wit, E., Rasmussen, A.L., et al. Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques. Nat Med 19:10 (2013), 1313–1317.
    • (2013) Nat Med , vol.19 , Issue.10 , pp. 1313-1317
    • Falzarano, D.1    de Wit, E.2    Rasmussen, A.L.3
  • 126
    • 84896695450 scopus 로고    scopus 로고
    • Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study
    • 126 Al-Tawfiq, J.A., Momattin, H., Dib, J., et al. Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study. Int J Infect Dis 20 (2014), 42–46.
    • (2014) Int J Infect Dis , vol.20 , pp. 42-46
    • Al-Tawfiq, J.A.1    Momattin, H.2    Dib, J.3
  • 127
    • 84936931504 scopus 로고    scopus 로고
    • IFN-α2a or IFN-β1a in combination with ribavirin to treat Middle East respiratory syndrome coronavirus pneumonia: a retrospective study
    • 127 Shalhoub, S., Farahat, F., Al-Jiffri, A., et al. IFN-α2a or IFN-β1a in combination with ribavirin to treat Middle East respiratory syndrome coronavirus pneumonia: a retrospective study. J Antimicrob Chemother 70:7 (2015), 2129–2132.
    • (2015) J Antimicrob Chemother , vol.70 , Issue.7 , pp. 2129-2132
    • Shalhoub, S.1    Farahat, F.2    Al-Jiffri, A.3
  • 128
    • 84908285527 scopus 로고    scopus 로고
    • Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study
    • 128 Omrani, A.S., Saad, M.M., Baig, K., et al. Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study. Lancet Infect Dis 14:11 (2014), 1090–1095.
    • (2014) Lancet Infect Dis , vol.14 , Issue.11 , pp. 1090-1095
    • Omrani, A.S.1    Saad, M.M.2    Baig, K.3
  • 129
    • 84911945010 scopus 로고    scopus 로고
    • Virological and serological analysis of a recent Middle East respiratory syndrome coronavirus infection case on a triple combination antiviral regimen
    • 129 Spanakis, N., Tsiodras, S., Haagmans, B.L., et al. Virological and serological analysis of a recent Middle East respiratory syndrome coronavirus infection case on a triple combination antiviral regimen. Int J Antimicrob Agents 44:6 (2014), 528–532.
    • (2014) Int J Antimicrob Agents , vol.44 , Issue.6 , pp. 528-532
    • Spanakis, N.1    Tsiodras, S.2    Haagmans, B.L.3
  • 130
    • 84906669535 scopus 로고    scopus 로고
    • Nitazoxanide: a first-in-class broad-spectrum antiviral agent
    • 130 Rossignol, J.F., Nitazoxanide: a first-in-class broad-spectrum antiviral agent. Antiviral Res 110 (2014), 94–103.
    • (2014) Antiviral Res , vol.110 , pp. 94-103
    • Rossignol, J.F.1
  • 131
    • 84896534867 scopus 로고    scopus 로고
    • Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection
    • 131 Arabi, Y., Arifi, A.A., Balkhy, H.H., et al. Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection. Ann Intern Med 160:6 (2014), 389–397.
    • (2014) Ann Intern Med , vol.160 , Issue.6 , pp. 389-397
    • Arabi, Y.1    Arifi, A.A.2    Balkhy, H.H.3
  • 132
    • 84877095981 scopus 로고    scopus 로고
    • Adjunctive therapies and immunomodulatory agents in the management of severe influenza
    • 132 Hui, D.S., Lee, N., Chan, P.K., Adjunctive therapies and immunomodulatory agents in the management of severe influenza. Antiviral Res 98:3 (2013), 410–416.
    • (2013) Antiviral Res , vol.98 , Issue.3 , pp. 410-416
    • Hui, D.S.1    Lee, N.2    Chan, P.K.3
  • 133
    • 84887019388 scopus 로고    scopus 로고
    • Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus
    • 133 Chan, J.F., Chan, K.H., Kao, R.Y., et al. Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus. J Infect 67:6 (2013), 606–616.
    • (2013) J Infect , vol.67 , Issue.6 , pp. 606-616
    • Chan, J.F.1    Chan, K.H.2    Kao, R.Y.3
  • 134
    • 84955391557 scopus 로고    scopus 로고
    • Treatment with lopinavir/ritonavir or interferon-β1b improves outcome of MERS-CoV infection in a nonhuman primate model of common marmoset
    • 134 Chan, J.F., Yao, Y., Yeung, M.L., et al. Treatment with lopinavir/ritonavir or interferon-β1b improves outcome of MERS-CoV infection in a nonhuman primate model of common marmoset. J Infect Dis 212:12 (2015), 1904–1913.
    • (2015) J Infect Dis , vol.212 , Issue.12 , pp. 1904-1913
    • Chan, J.F.1    Yao, Y.2    Yeung, M.L.3
  • 135
    • 84925234696 scopus 로고    scopus 로고
    • MERS CoV infection in two renal transplant recipients: case report
    • 135 AlGhamdi, M., Mushtaq, F., Awn, N., et al. MERS CoV infection in two renal transplant recipients: case report. Am J Transplant 15:4 (2015), 1101–1104.
    • (2015) Am J Transplant , vol.15 , Issue.4 , pp. 1101-1104
    • AlGhamdi, M.1    Mushtaq, F.2    Awn, N.3
  • 136
    • 84900515662 scopus 로고    scopus 로고
    • Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution
    • 136 Tang, X.C., Agnihothram, S.S., Jiao, Y., et al. Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution. Proc Natl Acad Sci U S A 111:19 (2014), E2018–E2026.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.19 , pp. E2018-E2026
    • Tang, X.C.1    Agnihothram, S.S.2    Jiao, Y.3
  • 137
    • 84961381392 scopus 로고    scopus 로고
    • 3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012
    • 137 Johnson, R.F., Bagci, U., Keith, L., et al. 3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012. Virology 490 (2016), 49–58.
    • (2016) Virology , vol.490 , pp. 49-58
    • Johnson, R.F.1    Bagci, U.2    Keith, L.3
  • 138
    • 84939863145 scopus 로고    scopus 로고
    • Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
    • 138 Corti, D., Zhao, J., Pedotti, M., et al. Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus. Proc Natl Acad Sci U S A 112:33 (2015), 10473–10478.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , Issue.33 , pp. 10473-10478
    • Corti, D.1    Zhao, J.2    Pedotti, M.3
  • 139
    • 84899797757 scopus 로고    scopus 로고
    • Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein
    • 139 Jiang, L., Wang, N., Zuo, T., et al. Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein. Sci Transl Med, 6(234), 2014, 234ra59.
    • (2014) Sci Transl Med , vol.6 , Issue.234 , pp. 234ra59
    • Jiang, L.1    Wang, N.2    Zuo, T.3
  • 140
    • 84973153410 scopus 로고    scopus 로고
    • Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo
    • 140 Luke, T., Wu, H., Zhao, J., et al. Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo. Sci Transl Med, 8(326), 2016, 326ra21.
    • (2016) Sci Transl Med , vol.8 , Issue.326 , pp. 326ra21
    • Luke, T.1    Wu, H.2    Zhao, J.3
  • 141
    • 84940777670 scopus 로고    scopus 로고
    • Intratracheal exposure of common marmosets to MERS-CoV Jordan-n3/2012 or MERS-CoV EMC/2012 isolates does not result in lethal disease
    • 141 Johnson, R.F., Via, L.E., Kumar, M.R., et al. Intratracheal exposure of common marmosets to MERS-CoV Jordan-n3/2012 or MERS-CoV EMC/2012 isolates does not result in lethal disease. Virology 485 (2015), 422–430.
    • (2015) Virology , vol.485 , pp. 422-430
    • Johnson, R.F.1    Via, L.E.2    Kumar, M.R.3
  • 142
    • 85011020725 scopus 로고    scopus 로고
    • Clinical management of severe acute respiratory infection when Middle East respiratory syndrome coronavirus (MERS-CoV) infection is suspected. Interim guidance. Available at: Accessed July 3, 2015.
    • 142 WHO. Clinical management of severe acute respiratory infection when Middle East respiratory syndrome coronavirus (MERS-CoV) infection is suspected. Interim guidance. 2015. Available at: http://apps.who.int/iris/bitstream/10665/178529/1/WHO_MERS_Clinical_15.1_eng.pdf. Accessed July 3, 2015.
    • (2015)
  • 144
    • 84882918127 scopus 로고    scopus 로고
    • Interhuman transmissibility of middle east respiratory syndrome coronavirus: estimation of pandemic risk
    • 144 Breban, R., Riou, J., Fontanet, A., Interhuman transmissibility of middle east respiratory syndrome coronavirus: estimation of pandemic risk. Lancet 382 (2013), 694–699.
    • (2013) Lancet , vol.382 , pp. 694-699
    • Breban, R.1    Riou, J.2    Fontanet, A.3
  • 145
    • 84891506244 scopus 로고    scopus 로고
    • Advancing priority research on the middle east respiratory syndrome coronavirus
    • 145 Hui, D.S., Zumla, A., Advancing priority research on the middle east respiratory syndrome coronavirus. J Infect Dis 209 (2014), 173–176.
    • (2014) J Infect Dis , vol.209 , pp. 173-176
    • Hui, D.S.1    Zumla, A.2
  • 146
    • 84962487236 scopus 로고    scopus 로고
    • SARS-like WIV1-CoV poised for human emergence
    • 146 Menachery, V.D., Yount, B.L. Jr., Sims, A.C., et al. SARS-like WIV1-CoV poised for human emergence. Proc Natl Acad Sci U S A 113:11 (2016), 3048–3053.
    • (2016) Proc Natl Acad Sci U S A , vol.113 , Issue.11 , pp. 3048-3053
    • Menachery, V.D.1    Yount, B.L.2    Sims, A.C.3


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