Intratracheal exposure of common marmosets to MERS-CoV Jordan-n3/2012 or MERS-CoV EMC/2012 isolates does not result in lethal disease

Virology

Volumn 485, Issue , 2015, Pages 422-430

  Johnson, Reed F ^a   Via, Laura E ^a   Kumar, Mia R ^a   Cornish, Joseph P ^a   Yellayi, Srikanth ^a   Huzella, Louis ^a   Postnikova, Elena ^a   Oberlander, Nicholas ^a   Bartos, Christopher ^a   Ork, Britini L ^a   Mazur, Steven ^a   Allan, Cindy ^a   Holbrook, Michael R ^a   Solomon, Jeffrey ^b   Johnson, Joshua C ^a   Pickel, James ^c   Hensley, Lisa E ^a   Jahrling, Peter B ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Animal model; Coronavirus; MERS; MERS CoV; Middle East Respiratory Syndrome; Nonhuman primate

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; BODY TEMPERATURE; BREATHING RATE; CALLITRICHINAE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE COURSE; INOCULATION; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS EMC/2012; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS JORDAN N3/2012; NONHUMAN; OXYGEN SATURATION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; VIRUS INACTIVATION; VIRUS INFECTION; VIRUS ISOLATION; VIRUS REPLICATION; VIRUS STRAIN; ANIMAL; BIOPSY; CALLITHRIX; CHLOROCEBUS AETHIOPS; CORONAVIRUS INFECTION; DISEASE MODEL; GENETICS; IMMUNOLOGY; KIDNEY; LUNG; MONKEY DISEASES; MORTALITY; PATHOLOGY; PHYSIOLOGY; SEVERITY OF ILLNESS INDEX; VERO CELL LINE; VETERINARY; VIROLOGY;

VIRUS ANTIBODY; VIRUS RNA;

ANIMALS; ANTIBODIES, VIRAL; BIOPSY; CALLITHRIX; CERCOPITHECUS AETHIOPS; CORONAVIRUS INFECTIONS; DISEASE MODELS, ANIMAL; KIDNEY; LUNG; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MONKEY DISEASES; RNA, VIRAL; SEVERITY OF ILLNESS INDEX; TOMOGRAPHY, X-RAY COMPUTED; VERO CELLS;

EID: 84940777670     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2015.07.013     Document Type: Article

References (23)

1. Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. Basic local alignment search tool. J. Mol. Biol. 1990, 215:403-410.
2. Arabi Y.M., Arifi A.A., Balkhy H.H., Najm H., Aldawood A.S., Ghabashi A., Hawa H., Alothman A., Khaldi A., Al Raiy B. Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection. Ann. Intern. Med. 2014, 160:389-397.
3. Assiri A., Al-Tawfiq J.A., Al-Rabeeah A.A., Al-Rabiah F.A., Al-Hajjar S., Al-Barrak A., Flemban H., Al-Nassir W.N., Balkhy H.H., Al-Hakeem R.F., Makhdoom H.Q., Zumla A.I., Memish Z.A. Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect. Dis. 2013, 13:752-761.
4. Channappanavar R., Fett C., Zhao J., Meyerholz D.K., Perlman S. Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection. J. Virol. 2014, 88:11034-11044.
5. Channappanavar R., Zhao J., Perlman S. T cell-mediated immune response to respiratory coronaviruses. Immunol. Res. 2014, 59:118-128.
6. Coleman C.M., Matthews K.L., Goicochea L., Frieman M.B. Wild-type and innate immune-deficient mice are not susceptible to the Middle East respiratory syndrome coronavirus. J. Gen. Virol. 2014, 95:408-412.
7. Cotten M., Lam T.T., Watson S.J., Palser A.L., Petrova V., Grant P., Pybus O.G., Rambaut A., Guan Y., Pillay D., Kellam P., Nastouli E. Full-genome deep sequencing and phylogenetic analysis of novel human betacoronavirus. Emerg. Infect. Dis. 2013, 19:736-742b.
8. de Wit E., Rasmussen A.L., Falzarano D., Bushmaker T., Feldmann F., Brining D.L., Fischer E.R., Martellaro C., Okumura A., Chang J., Scott D., Benecke A.G., Katze M.G., Feldmann H., Munster V.J. Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques. Proc. Natl. Acad. Sci. USA 2013, 110:16598-16603.
9. Dyall J., Johnson R.F., Chen D.Y., Huzella L., Ragland D.R., Mollura D.J., Byrum R., Reba R.C., Jennings G., Jahrling P.B., Blaney J.E., Paragas J. Evaluation of monkeypox disease progression by molecular imaging. J. Infect. Dis. 2011, 204:1902-1911.
10. Elke G., Fuld M.K., Halaweish A.F., Grychtol B., Weiler N., Hoffman E.A., Frerichs I. Quantification of ventilation distribution in regional lung injury by electrical impedance tomography and xenon computed tomography. Physiol. Meas. 2013, 34:1303-1318.
11. Falzarano D., de Wit E., Feldmann F., Rasmussen A.L., Okumura A., Peng X., Thomas M.J., van Doremalen N., Haddock E., Nagy L., LaCasse R., Liu T., Zhu J., McLellan J.S., Scott D.P., Katze M.G., Feldmann H., Munster V.J. Infection with MERS-CoV causes lethal pneumonia in the common marmoset. PLoS Pathog. 2014, 10:e1004250.
12. Falzarano D., de Wit E., Rasmussen A.L., Feldmann F., Okumura A., Scott D.P., Brining D., Bushmaker T., Martellaro C., Baseler L., Benecke A.G., Katze M.G., Munster V.J., Feldmann H. Treatment with interferon-alpha2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques. Nat. Med. 2013, 19:1313-1317.
13. Frey K.G., Redden C.L., Bishop-Lilly K.A., Johnson R., Hensley L.E., Raviprakash K., Luke T., Kochel T., Mokashi V.P., Defang GN. Full-genome sequence of human betacoronavirus 2c Jordan-N3/2012 after serial passage in mammalian cells. Genome Announc. 2014, 2(3). e00324-14. 10.1128/genomeA.00324-14.
14. Goujon M., McWilliam H., Li W., Valentin F., Squizzato S., Paern J., Lopez R. A new bioinformatics analysis tools framework at EMBL-EBI. Nucleic Acids Res. 2010, 38:W695-W699.
15. Jonsson C.B., Camp J.V., Wu A., Zheng H., Kraenzle J.L., Biller A.E., Vanover C.D., Chu Y.K., Ng C.K., Proctor M., Sherwood L., Steffen M.C., Mollura D.J. Molecular imaging reveals a progressive pulmonary inflammation in lower airways in ferrets infected with 2009 H1N1 pandemic influenza virus. PLoS One 2012, 7:e40094.
16. Li M., Jirapatnakul A., Biancardi A., Riccio M.L., Weiss R.S., Reeves A.P. Growth pattern analysis of murine lung neoplasms by advanced semi-automated quantification of micro-CT images. PLoS One 2013, 8:e83806.
17. McWilliam H., Li W., Uludag M., Squizzato S., Park Y.M., Buso N., Cowley A.P., Lopez R. Analysis tool web services from the EMBL-EBI. Nucleic Acids Res. 2013, 41:W597-W600.
18. Romanova A.L., Nemeth A.J., Berman M.D., Guth J.C., Liotta E.M., Naidech A.M., Maas M.B. Magnetic resonance imaging versus computed tomography for identification and quantification of intraventricular hemorrhage. J. Stroke Cerebrovasc. Dis.: Off. J. Natl. Stroke Assoc. 2014, 23:2036-2040.
19. Sievers F., Wilm A., Dineen D., Gibson T.J., Karplus K., Li W., Lopez R., McWilliam H., Remmert M., Soding J., Thompson J.D., Higgins D.G. Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega. Mol. Syst. Biol. 2011, 7:539.
20. Via L.E., Weiner D.M., Schimel D., Lin P.L., Dayao E., Tankersley S.L., Cai Y., Coleman M.T., Tomko J., Paripati P., Orandle M., Kastenmayer R.J., Tartakovsky M., Rosenthal A., Portevin D., Eum S.Y., Lahouar S., Gagneux S., Young D.B., Flynn J.L., Barry C.E. Differential virulence and disease progression following Mycobacterium tuberculosis complex infection of the common marmoset (Callithrix jacchus). Infect. Immun. 2013, 81:2909-2919.
21. Yao Y., Bao L., Deng W., Xu L., Li F., Lv Q., Yu P., Chen T., Xu Y., Zhu H., Yuan J., Gu S., Wei Q., Chen H., Yuen K.Y., Qin C. An animal model of MERS produced by infection of rhesus macaques with MERS coronavirus. J. Infect. Dis. 2014, 209:236-242.
22. Zaki A.M., van Boheemen S., Bestebroer T.M., Osterhaus A.D., Fouchier R.A. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N. Engl. J. Med. 2012, 367:1814-1820.
23. Zhao J., Li K., Wohlford-Lenane C., Agnihothram S.S., Fett C., Zhao J., Gale M.J., Baric R.S., Enjuanes L., Gallagher T., McCray P.B., Perlman S. Rapid generation of a mouse model for Middle East respiratory syndrome. Proc. Natl. Acad. Sci. USA 2014, 111:4970-4975.