Ultrasonic-assisted synthesis of 1,4-disubstituted 1,2,3-triazoles via various terminal acetylenes and azide and their quorum sensing inhibition

Ultrasonics Sonochemistry

Volumn 36, Issue , 2017, Pages 343-353

  Zhang, Da wei ^a   Zhang, Yu min ^a   Li, Jing ^a   Zhao, Tian qi ^a   Gu, Qiang ^a   Lin, Feng ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

1,2,3 Triazole; 1,3 Dispolar cycloaddition; Isoxazole; Quorum sensing; Thymidine; Ultrasonic heating

Indexed keywords

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

1,2,3-TRIAZOLE; ISOXAZOLES; QUORUM-SENSING; THYMIDINE; ULTRASONIC HEATING;

COPPER COMPOUNDS;

1 [ 4 HYDROXY 5 [[4 [[(3 PHENYLISOXAZOL 5 YL) METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 4 HYDROXY 5 [[4 [[[3 (2 METHOXYPHENYL)ISOXAZOL 5 YL]METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 4 HYDROXY 5 [[4 [[[3 (3 NITROPHENYL)ISOXAZOL 5 YL]METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 4 HYDROXY 5 [[4 [[[3 (4 METHOXYPHENYL)ISOXAZOL 5 YL]METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 4 HYDROXY 5 [[4 [[[3 (PARA TOLYL)ISOXAZOL 5 YL]METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 4 HYDROXY 5 [[4 [[[3 (PYRIDIN 2 YL)ISOXAZOL 5 YL]METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 4 HYDROXY 5 [[4 [[[3 (STYRYL)ISOXAZOL 5 YL]METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 4 [4 [[[3 (2 CHLOROPHENYL)ISOXAZOL 5 YL]METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 4 [4 [[[3 [4 (TERT BUTYL)PHENYL]ISOXAZOL 5 YL]METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 5 (HYDROXYMETHYL) 4 [4 [[(3 PHENYLISOXAZOL 5 YL)METHOXY]METHYL] 1H 1,2, 3 TRIAZOL 1 YL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 5 (HYDROXYMETHYL) 4 [4 [[[3 (3 NITROPHENYL)ISOXAZOL 5 YL]METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 5 (HYDROXYMETHYL) 4 [4 [[[3 (4 METHOXYPHENYL)METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 5 (HYDROXYMETHYL) 4 [4 [[[3 (PARA TOLYL)ISOXAZOL 5 YL]METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 5 [[4 [[[3 (2 CHLOROPHENYL)ISOXAZOL 5 Y] METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL] 4 HYDROXYTETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 5 [[4 [[[3 (4 BROMOPHENYL)ISOXAZOL 5 YL]METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 5 [[4 [[[3 (4 CHLOROPHENYL)ISOXAZOL 5 Y] METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL] 4 HYDROXYTETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 5 [[4 [[[3 (4 FLUOROPHENYL)ISOXAZOL 5 YL]METHOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]METHYL]TETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1 [ 5 [[4 [[[3 [4 (TERT BUTYL)PHENYL]ISOXAZOL 5 YL]METHOXY]METHYL] 1H1,2,3 TRIAZOL 1 YL]METHYL] 4 HYDROXYTETRAHYDROFURAN 2 YL] 5 METHYLPYRIMIDINE 2,4(1H,3H) DIONE; 1,2,3 TRIAZOLE DERIVATIVE; ACETYLENE DERIVATIVE; ANTIBIOTIC AGENT; AZIDE; HOMOSERINE; LACTONE DERIVATIVE; N DECANOYL LEVO HOMOSERINE LACTONE; UNCLASSIFIED DRUG; ALKYNE; ANTIINFECTIVE AGENT; TRIAZOLE DERIVATIVE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYST; CHROMOBACTERIUM VIOLACEUM; CONTROLLED STUDY; CYCLOADDITION; DIMERIZATION; DRUG SYNTHESIS; IC50; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUORUM SENSING; ULTRASOUND; CHEMISTRY; CHROMOBACTERIUM; CYTOLOGY; DRUG EFFECT; SYNTHESIS;

ALKYNES; ANTI-BACTERIAL AGENTS; AZIDES; CHEMISTRY TECHNIQUES, SYNTHETIC; CHROMOBACTERIUM; QUORUM SENSING; TRIAZOLES; ULTRASONIC WAVES;

EID: 85006264100     PISSN: 13504177     EISSN: 18732828     Source Type: Journal    
DOI: 10.1016/j.ultsonch.2016.12.011     Document Type: Article

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