Synthesis and anticancer activity evaluation of new 1,2,3-triazole-4- carboxamide derivatives

Medicinal Chemistry Research

Volumn 23, Issue 5, 2014, Pages 2426-2438

  Pokhodylo, Nazariy ^a   Shyyka, Olga ^a   Matiychuk, Vasyl ^a  

^a IVAN FRANKO NATIONAL UNIVERSITY OF LVIV   (Ukraine)

Author keywords

1,2,3 triazole 4 carboxamide; Anticancer activity; COMPARE analysis; Molecular docking

Indexed keywords

1 (3 (4 CHLOROPHENYL)BENZO[C]ISOXAZOL 5 YL) N (3 METHOXYPHENYL) 5 METHYL 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 1 [3 (4 CHLOROPHENYL) 2,1 BENZISOXAZOL 5 YL] N (FURAN 2 YLMETHYL) 5 METHYL 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 1,2,3 TRIAZOLE DERIVATIVE; 5 AMINO 1 (3,5 DIMETHYLPHENYL) N (1 METHYLETHYL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 5 AMINO N (2,4 DICHLOROPHENYL) 1 (2 METHYLPHENYL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 5 AMINO N (2,4 DIMETHOXYPHENYL) 1 (4 FLUOROPHENYL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 5 AMINO N (2,4 DIMETHOXYPHENYL) 1 [3 (TRIFLUOROMETHYL) PHENYL] 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 5 AMINO N (2,5 DICHLOROPHENYL) 1 (4 METHYLPHENYL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 5 AMINO N (2,6 DIMETHYLPHENYL) 1 (4 FLUOROPHENYL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 5 AMINO N (4 ETHYLPHENYL) 1 (4 METHOXYPHENYL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 5 AMINO N (4 FLUOROPHENYL) 1 [3 (TRIFLUOROMETHYL)PHENYL] 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 5 AMINO N (4 METHOXYPHENYL) 1 (4 METHYLPHENYL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 5 AMINO N (5 ETHYL 1,3,4 THIADIAZOL 2 YL) 1 (4 METHYLPHENYL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 5 AMINO N BENZYL 1 (4 METHYLPHENYL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 5 AMINO N CYCLOPENTYL 1 [3 (TRIFLUOROMETHYL)PHENYL] 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; 5 METHYL 1 (3 PHENYL 2,1 BENZISOXAZOL 5 YL) N [3 (TRIFLUOROMETHYL)PHENYL] 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; ANTINEOPLASTIC AGENT; CARBOXYLIC ACID DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; N (2 CHLOROPHENYL) 5 ETHYL 1 (3 PHENYL 2,1 BENZISOXAZOL 5 YL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (3 CHLOROPHENYL) 5 ETHYL 1 (3 PHENYL 2,1 BENZISOXAZOL 5 YL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (4 CHLOROPHENYL) 5 ETHYL 1 (3 PHENYL 2,1 BENZISOXAZOL 5 YL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (5 BENZYL 1,3 THIAZOL 2 YL) 1 (2 METHOXYPHENYL) 5 METHYL 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (5 BENZYL 1,3 THIAZOL 2 YL) 5 METHYL 1 PHENYL 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N [5 (3 CHLOROBENZYL) 1,3 THIAZOL 2 YL] 5 METHYL 1 (4 METHYLPHENYL) 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BRAIN CANCER; BREAST CANCER; CANCER CELL; DRUG SYNTHESIS; HUMAN; HUMAN CELL; KIDNEY CANCER; LEUKEMIA; LUNG NON SMALL CELL CANCER; MELANOMA; MOLECULAR DOCKING; OVARY CANCER;

EID: 84898775033     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-013-0841-8     Document Type: Article

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