Design, synthesis, and antitumor activity of bile acid-polyamine-nucleoside conjugates

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 11, 2007, Pages 2983-2986

  Wu, Dimao ^a   Ji, Sanhao ^a   Wu, Yan ^a   Ju, Yong ^a,b   Zhao, Yufen ^a  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b LANZHOU UNIVERSITY   (China)

Author keywords

3 Azido 3 deoxythymidine (AZT); Antitumor prodrug; Bile acid; Conjugate; Phosphoramidate; Polyamine

Indexed keywords

AMIDE; BILE ACID; BILE ACID CONJUGATE; CISPLATIN; FLUOROURACIL; NUCLEOSIDE DERIVATIVE; PACLITAXEL; POLYAMINE DERIVATIVE; PRODRUG; ZIDOVUDINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOASSAY; CANCER; CANCER THERAPY; COMBINATION CHEMOTHERAPY; DRUG BIOAVAILABILITY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG MECHANISM; DRUG STABILITY; DRUG STRUCTURE; HELA CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; KIDNEY CANCER; UTERINE CERVIX CANCER;

AMIDES; ANTINEOPLASTIC AGENTS; BILE ACIDS AND SALTS; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; DRUG DESIGN; HELA CELLS; HUMANS; NUCLEOSIDES; PHOSPHORIC ACIDS; POLYAMINES; PRODRUGS; ZIDOVUDINE;

EID: 34247895612     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.03.067     Document Type: Article

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