5′-silylated 3′-1,2,3-triazolyl thymidine analogues as inhibitors of West Nile Virus and Dengue virus

Journal of Medicinal Chemistry

Volumn 58, Issue 9, 2015, Pages 4016-4028

  Vernekar, Sanjeev Kumar V ^a   Qiu, Li ^a   Zhang, Jing ^b   Kankanala, Jayakanth ^a   Li, Hongmin ^b,c   Geraghty, Robert J ^a   Wang, Zhengqiang ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b WADSWORTH CENTER   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 SILYLATED 3 1,2,3 TRIAZOLYL THYMIDINE DERIVATIVE; 5 SILYLATED NUCLEOSIDE; METHYLTRANSFERASE; NUCLEOSIDE; S ADENOSYLMETHIONINE; THYMIDINE DERIVATIVE; TRIAZOLE; UNCLASSIFIED DRUG; ZIDOVUDINE; ANTIVIRUS AGENT; SILANE DERIVATIVE; TRIAZOLE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING ASSAY; CONTROLLED STUDY; DENGUE VIRUS; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR MODEL; PLAQUE ASSAY; STRUCTURE ACTIVITY RELATION; WEST NILE VIRUS; ANALOGS AND DERIVATIVES; BINDING COMPETITION; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; MOLECULAR DOCKING; STEREOISOMERISM;

ANTIVIRAL AGENTS; BINDING, COMPETITIVE; DENGUE VIRUS; DOSE-RESPONSE RELATIONSHIP, DRUG; HIV-1; METHYLTRANSFERASES; MOLECULAR DOCKING SIMULATION; S-ADENOSYLMETHIONINE; SILANES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES; WEST NILE VIRUS; ZIDOVUDINE;

EID: 84929346603     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.5b00327     Document Type: Article

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