메뉴 건너뛰기




Volumn 6, Issue 3, 2016, Pages 272-286

Research for new drugs for elimination of onchocerciasis in Africa

Author keywords

Africa; Discovery; Drug development; Elimination; Implementation research; Onchocerciasis

Indexed keywords

ALBENDAZOLE; EMODEPSIDE; FLUBENDAZOLE; IVERMECTIN; MOXIDECTIN; NEW DRUG; ANTIFILARIAL AGENT;

EID: 84999736795     PISSN: None     EISSN: 22113207     Source Type: Journal    
DOI: 10.1016/j.ijpddr.2016.04.002     Document Type: Review
Times cited : (66)

References (169)
  • 1
    • 84966293178 scopus 로고    scopus 로고
    • Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis
    • Abegunde, A.T., Ahuja, R.M., Okafor, N.J., Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis. Cochrane. Database. Syst. Rev., 1, 2016, CD011146.
    • (2016) Cochrane. Database. Syst. Rev. , vol.1 , pp. CD011146
    • Abegunde, A.T.1    Ahuja, R.M.2    Okafor, N.J.3
  • 2
    • 85006471791 scopus 로고    scopus 로고
    • 2009 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control
    • (Ouagadougou)
    • African Programme for Onchocerciasis Control (APOC), 2009 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control., 2009 (Ouagadougou).
    • (2009)
    • African Programme for Onchocerciasis Control (APOC)1
  • 3
    • 85006389865 scopus 로고    scopus 로고
    • 2010 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control
    • (Ouagadougou)
    • African Programme for Onchocerciasis Control (APOC), 2010 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control., 2010 http://www.who.int/entity/apoc/publications/APR_2010_EN_28Oct2010_Progress_report_final_printed_version.pdf (Ouagadougou).
    • (2010)
    • African Programme for Onchocerciasis Control (APOC)1
  • 4
    • 84857944312 scopus 로고    scopus 로고
    • Conceptual and operational framework of onchocerciasis elimination with ivermectin treatment
    • WHO/APOC/MG/10.1 World Health Organization/African Programme for Onchocerciasis Control (WHO/APOC/MG/10.1) (Ouagadougou)
    • African Programme for Onchocerciasis Control (APOC), Conceptual and operational framework of onchocerciasis elimination with ivermectin treatment. WHO/APOC/MG/10.1, (eds.) African Programme for Onchocerciasis Control, 2010, World Health Organization/African Programme for Onchocerciasis Control (WHO/APOC/MG/10.1) www.who.int/apoc/oncho_elimination_report_english.pdf (Ouagadougou).
    • (2010) African Programme for Onchocerciasis Control
    • African Programme for Onchocerciasis Control (APOC)1
  • 5
    • 85006455153 scopus 로고    scopus 로고
    • 2011 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control
    • (Ouagadougou)
    • African Programme for Onchocerciasis Control (APOC), 2011 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control., 2011 http://www.who.int/entity/apoc/publications/JZF17_OK_EN_APOC_ProgressReport2011.pdf (Ouagadougou).
    • (2011)
    • African Programme for Onchocerciasis Control (APOC)1
  • 6
    • 85006338785 scopus 로고    scopus 로고
    • 2012 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control
    • (Ouagadougou)
    • African Programme for Onchocerciasis Control (APOC), 2012 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control., 2012 http://www.who.int/entity/apoc/publications/ENAPOCPR2012_ProgressReport2012.pdf (Ouagadougou).
    • (2012)
    • African Programme for Onchocerciasis Control (APOC)1
  • 7
    • 85006458907 scopus 로고    scopus 로고
    • Final Communiqué of the 18th Session of the Joint Action Forum (JAF18) of APOC
    • African Programme for Onchocerciasis Control (APOC), Final Communiqué of the 18th Session of the Joint Action Forum (JAF18) of APOC. 2012 http://www.who.int/apoc/publications/recommendations/en/index.html].
    • (2012)
    • African Programme for Onchocerciasis Control (APOC)1
  • 8
    • 85006330154 scopus 로고    scopus 로고
    • 2013 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control
    • (Ouagadougou)
    • African Programme for Onchocerciasis Control (APOC), 2013 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control., 2013 (Ouagadougou).
    • (2013)
    • African Programme for Onchocerciasis Control (APOC)1
  • 9
    • 85006438165 scopus 로고    scopus 로고
    • 2014 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control
    • African Programme for Onchocerciasis Control (APOC), 2014 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control., 2014.
    • (2014)
    • African Programme for Onchocerciasis Control (APOC)1
  • 10
    • 85006453969 scopus 로고    scopus 로고
    • 2015 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control
    • (Ouagadougou)
    • African Programme for Onchocerciasis Control (APOC), 2015 Progress ReportWorld Health Organization/African Programme for Onchocerciasis Control., 2015 (Ouagadougou).
    • (2015)
    • African Programme for Onchocerciasis Control (APOC)1
  • 12
    • 84919485386 scopus 로고    scopus 로고
    • Assessing resources for implementing a community directed intervention (CDI) strategy in delivering multiple health interventions in urban poor communities in Southwestern Nigeria: a qualitative study
    • Ajayi, I.O., Jegede, A.S., Falade, C.O., Sommerfeld, J., Assessing resources for implementing a community directed intervention (CDI) strategy in delivering multiple health interventions in urban poor communities in Southwestern Nigeria: a qualitative study. Infect. Dis. Poverty, 2, 2013, 25.
    • (2013) Infect. Dis. Poverty , vol.2 , pp. 25
    • Ajayi, I.O.1    Jegede, A.S.2    Falade, C.O.3    Sommerfeld, J.4
  • 13
    • 84963039366 scopus 로고
    • The first use of ivermectin for the treatment of onchocerciasis in Yemen
    • Al-Qubati, Y., The first use of ivermectin for the treatment of onchocerciasis in Yemen. Trans. R. Soc. Trop. Med. Hyg., 88, 1994, 343.
    • (1994) Trans. R. Soc. Trop. Med. Hyg. , vol.88 , pp. 343
    • Al-Qubati, Y.1
  • 14
    • 6844226207 scopus 로고    scopus 로고
    • Onchodermatitis (sowda) in patients in Yemen. Clinical and histologic course after treatment with ivermectin
    • Al-Qubati, Y., Reynouard, F., Kumar, F., Gaxotte, P., Richard-Lenoble, D., Onchodermatitis (sowda) in patients in Yemen. Clinical and histologic course after treatment with ivermectin. Sante 7 (1997), 391–395.
    • (1997) Sante , vol.7 , pp. 391-395
    • Al-Qubati, Y.1    Reynouard, F.2    Kumar, F.3    Gaxotte, P.4    Richard-Lenoble, D.5
  • 15
    • 0036801051 scopus 로고    scopus 로고
    • Immunocompetence may be important in the effectiveness of Mectizan (ivermectin) in the treatment of human onchocerciasis
    • Ali, M.M., Mukhtar, M.M., Baraka, O.Z., Homeida, M.M., Kheir, M.M., Mackenzie, C.D., Immunocompetence may be important in the effectiveness of Mectizan (ivermectin) in the treatment of human onchocerciasis. Acta Trop. 84 (2002), 49–53.
    • (2002) Acta Trop. , vol.84 , pp. 49-53
    • Ali, M.M.1    Mukhtar, M.M.2    Baraka, O.Z.3    Homeida, M.M.4    Kheir, M.M.5    Mackenzie, C.D.6
  • 16
    • 0019513481 scopus 로고
    • Loasis as a possible trigger of African endomyocardial fibrosis: a case report from Nigeria
    • Andy, J.J., Bishara, F.F., Soyinka, O.O., Odesanmi, W.O., Loasis as a possible trigger of African endomyocardial fibrosis: a case report from Nigeria. Acta Trop. 38 (1981), 179–186.
    • (1981) Acta Trop. , vol.38 , pp. 179-186
    • Andy, J.J.1    Bishara, F.F.2    Soyinka, O.O.3    Odesanmi, W.O.4
  • 17
    • 84884692755 scopus 로고    scopus 로고
    • Progress towards eliminating onchocerciasis in the WHO region of the Americas: verification by WHO of elimination of transmission in Colombia
    • Anonymous, Progress towards eliminating onchocerciasis in the WHO region of the Americas: verification by WHO of elimination of transmission in Colombia. Wkly. Epidemiol. Rec. 88 (2013), 381–385.
    • (2013) Wkly. Epidemiol. Rec. , vol.88 , pp. 381-385
    • Anonymous1
  • 18
    • 84952785163 scopus 로고    scopus 로고
    • Progress toward eliminating onchocerciasis in the WHO region of the Americas: verification of elimination of transmission in Mexico
    • Anonymous, Progress toward eliminating onchocerciasis in the WHO region of the Americas: verification of elimination of transmission in Mexico. Wkly. Epidemiol. Rec. 90 (2015), 577–581.
    • (2015) Wkly. Epidemiol. Rec. , vol.90 , pp. 577-581
    • Anonymous1
  • 19
    • 0018821163 scopus 로고
    • The chemotherapy of onchocerciasis II. Quantitation of the clinical reaction to microfilaricides
    • Awadzi, K., The chemotherapy of onchocerciasis II. Quantitation of the clinical reaction to microfilaricides. Ann. Trop. Med. Parasitol. 74 (1980), 189–197.
    • (1980) Ann. Trop. Med. Parasitol. , vol.74 , pp. 189-197
    • Awadzi, K.1
  • 20
  • 21
    • 0032937972 scopus 로고    scopus 로고
    • The effects of high-dose ivermectin regimens on Onchocerca volvulus in onchocerciasis patients
    • Awadzi, K., Attah, S.K., Addy, E.T., Opoku, N.O., Quartey, B.T., The effects of high-dose ivermectin regimens on Onchocerca volvulus in onchocerciasis patients. Trans. R. Soc. Trop. Med. Hyg. 93 (1999), 189–194.
    • (1999) Trans. R. Soc. Trop. Med. Hyg. , vol.93 , pp. 189-194
    • Awadzi, K.1    Attah, S.K.2    Addy, E.T.3    Opoku, N.O.4    Quartey, B.T.5
  • 24
    • 0025346231 scopus 로고
    • Reactions to ivermectin treatment in onchocerciasis patients
    • Awadzi, K., Dadzie, K.Y., De, S.G., Remme, J., Reactions to ivermectin treatment in onchocerciasis patients. Acta Leiden. 59 (1990), 193–199.
    • (1990) Acta Leiden. , vol.59 , pp. 193-199
    • Awadzi, K.1    Dadzie, K.Y.2    De, S.G.3    Remme, J.4
  • 26
    • 0026788540 scopus 로고
    • Diethylcarbamazine in the treatment of patients with onchocerciasis
    • Awadzi, K., Gilles, H.M., Diethylcarbamazine in the treatment of patients with onchocerciasis. Br. J. Clin. Pharmacol. 34 (1992), 281–288.
    • (1992) Br. J. Clin. Pharmacol. , vol.34 , pp. 281-288
    • Awadzi, K.1    Gilles, H.M.2
  • 27
    • 84903471480 scopus 로고    scopus 로고
    • A randomized, single-ascending-dose, ivermectin-controlled, double-blind study of moxidectin in onchocerca volvulus infection
    • Awadzi, K., Opoku, N.O., Attah, S.K., Lazdins-Helds, J., Kuesel, A.C., A randomized, single-ascending-dose, ivermectin-controlled, double-blind study of moxidectin in onchocerca volvulus infection. PLoS.Negl. Trop. Dis., 8, 2014, e2953.
    • (2014) PLoS.Negl. Trop. Dis. , vol.8 , pp. e2953
    • Awadzi, K.1    Opoku, N.O.2    Attah, S.K.3    Lazdins-Helds, J.4    Kuesel, A.C.5
  • 28
    • 85006472482 scopus 로고    scopus 로고
    • Is O. volvulus suboptimal response to ivermectin a result of selection under ivermectin pressure? Insights from a study comparing ivermectin and moxidectin in areas without prior ivermectin mass treatment
    • 431
    • Bakajika, D.K., Kanza, E., Howard, H., Opoku, N., Tchatchu, J.-P.L., Kataliko, K., Kwapor, M., Attah, S.K., Vaillant, M., Olliaro, P., Halleux, C.M., Kuesel, A.C., Is O. volvulus suboptimal response to ivermectin a result of selection under ivermectin pressure? Insights from a study comparing ivermectin and moxidectin in areas without prior ivermectin mass treatment. Am. J. Trop. Med. Hyg., 89(Suppl. l.), 2013 431.
    • (2013) Am. J. Trop. Med. Hyg. , vol.89
    • Bakajika, D.K.1    Kanza, E.2    Howard, H.3    Opoku, N.4    Tchatchu, J.-P.L.5    Kataliko, K.6    Kwapor, M.7    Attah, S.K.8    Vaillant, M.9    Olliaro, P.10    Halleux, C.M.11    Kuesel, A.C.12
  • 29
    • 61849096677 scopus 로고    scopus 로고
    • Onchocerca-Simulium interactions and the population and evolutionary biology of Onchocerca volvulus
    • Basanez, M.G., Churcher, T.S., Grillet, M.E., Onchocerca-Simulium interactions and the population and evolutionary biology of Onchocerca volvulus. Adv. Parasitol. 68 (2009), 263–313.
    • (2009) Adv. Parasitol. , vol.68 , pp. 263-313
    • Basanez, M.G.1    Churcher, T.S.2    Grillet, M.E.3
  • 31
    • 0035450930 scopus 로고    scopus 로고
    • Models for the population biology and control of human onchocerciasis
    • Basanez, M.G., Ricardez-Esquinca, J., Models for the population biology and control of human onchocerciasis. Trends Parasitol. 17 (2001), 430–438.
    • (2001) Trends Parasitol. , vol.17 , pp. 430-438
    • Basanez, M.G.1    Ricardez-Esquinca, J.2
  • 32
    • 0031897090 scopus 로고    scopus 로고
    • The onchocerciasis control program in West Africa (OCP): essential characteristics
    • Benton, B., Dadzie, Y., Boatin, B., The onchocerciasis control program in West Africa (OCP): essential characteristics. Sante, 8, 1998, 26.
    • (1998) Sante , vol.8 , pp. 26
    • Benton, B.1    Dadzie, Y.2    Boatin, B.3
  • 33
    • 0018823055 scopus 로고
    • Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate
    • Bird, A.C., el-Sheikh, H., Anderson, J., Fuglsang, H., Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate. Br. J. Ophthalmol. 64 (1980), 191–200.
    • (1980) Br. J. Ophthalmol. , vol.64 , pp. 191-200
    • Bird, A.C.1    el-Sheikh, H.2    Anderson, J.3    Fuglsang, H.4
  • 34
    • 55849099995 scopus 로고    scopus 로고
    • The onchocerciasis control programme in West Africa (OCP)
    • Boatin, B., The onchocerciasis control programme in West Africa (OCP). Ann. Trop. Med. Parasitol. 102:Suppl. 1 (2008), 13–17.
    • (2008) Ann. Trop. Med. Parasitol. , vol.102 , pp. 13-17
    • Boatin, B.1
  • 35
    • 33646904206 scopus 로고    scopus 로고
    • Control of onchocerciasis
    • Boatin, B.A., Richards, F.O. Jr., Control of onchocerciasis. Adv. Parasitol. 61 (2006), 349–394.
    • (2006) Adv. Parasitol. , vol.61 , pp. 349-394
    • Boatin, B.A.1    Richards, F.O.2
  • 36
    • 0027428378 scopus 로고
    • Prophylactic activity of tetracycline against Brugia pahangi infection in jirds (Meriones unguiculatus)
    • Bosshardt, S.C., McCall, J.W., Coleman, S.U., Jones, K.L., Petit, T.A., Klei, T.R., Prophylactic activity of tetracycline against Brugia pahangi infection in jirds (Meriones unguiculatus). J. Parasitol. 79 (1993), 775–777.
    • (1993) J. Parasitol. , vol.79 , pp. 775-777
    • Bosshardt, S.C.1    McCall, J.W.2    Coleman, S.U.3    Jones, K.L.4    Petit, T.A.5    Klei, T.R.6
  • 38
    • 2942618342 scopus 로고    scopus 로고
    • Clinical picture, epidemiology and outcome of Loa-associated serious adverse events related to mass ivermectin treatment of onchocerciasis in Cameroon
    • Boussinesq, M., Gardon, J., Gardon-Wendel, N., Chippaux, J.P., Clinical picture, epidemiology and outcome of Loa-associated serious adverse events related to mass ivermectin treatment of onchocerciasis in Cameroon. Filaria. J., 2(Suppl. 1), 2003, S4.
    • (2003) Filaria. J. , vol.2 , pp. S4
    • Boussinesq, M.1    Gardon, J.2    Gardon-Wendel, N.3    Chippaux, J.P.4
  • 41
    • 84946732049 scopus 로고    scopus 로고
    • The potential for community-directed interventions: reaching underserved populations in Africa
    • Brieger, W.R., Sommerfeld, J.U., Amazigo, U.V., The potential for community-directed interventions: reaching underserved populations in Africa. Int. Q.Community Health Educ. 35 (2015), 295–316.
    • (2015) Int. Q.Community Health Educ. , vol.35 , pp. 295-316
    • Brieger, W.R.1    Sommerfeld, J.U.2    Amazigo, U.V.3
  • 42
    • 2942514530 scopus 로고    scopus 로고
    • Obligatory symbiotic Wolbachia endobacteria are absent from Loa loa
    • Buttner, D.W., Wanji, S., Bazzocchi, C., Bain, O., Fischer, P., Obligatory symbiotic Wolbachia endobacteria are absent from Loa loa. Filaria. J., 2, 2003, 10.
    • (2003) Filaria. J. , vol.2 , pp. 10
    • Buttner, D.W.1    Wanji, S.2    Bazzocchi, C.3    Bain, O.4    Fischer, P.5
  • 43
    • 84860539108 scopus 로고    scopus 로고
    • History of avermectin and ivermectin, with notes on the history of other macrocyclic lactone antiparasitic agents
    • Campbell, W.C., History of avermectin and ivermectin, with notes on the history of other macrocyclic lactone antiparasitic agents. Curr. Pharm. Biotechnol. 13 (2012), 853–865.
    • (2012) Curr. Pharm. Biotechnol. , vol.13 , pp. 853-865
    • Campbell, W.C.1
  • 44
    • 70349838505 scopus 로고    scopus 로고
    • Flubendazole in cystic echinococcosis therapy: pharmaco-parasitological evaluation in mice
    • Ceballos, L., Elissondo, M., Bruni, S.S., Denegri, G., Alvarez, L., Lanusse, C., Flubendazole in cystic echinococcosis therapy: pharmaco-parasitological evaluation in mice. Parasitol. Int. 58 (2009), 354–358.
    • (2009) Parasitol. Int. , vol.58 , pp. 354-358
    • Ceballos, L.1    Elissondo, M.2    Bruni, S.S.3    Denegri, G.4    Alvarez, L.5    Lanusse, C.6
  • 45
    • 84901815702 scopus 로고    scopus 로고
    • Exploring the potential of flubendazole in filariasis control: evaluation of the systemic exposure for different pharmaceutical preparations
    • Ceballos, L., Mackenzie, C., Geary, T., Alvarez, L., Lanusse, C., Exploring the potential of flubendazole in filariasis control: evaluation of the systemic exposure for different pharmaceutical preparations. PLoS.Negl. Trop. Dis., 8, 2014, e2838.
    • (2014) PLoS.Negl. Trop. Dis. , vol.8 , pp. e2838
    • Ceballos, L.1    Mackenzie, C.2    Geary, T.3    Alvarez, L.4    Lanusse, C.5
  • 46
    • 84878328410 scopus 로고    scopus 로고
    • Progress toward elimination of onchocerciasis in the americas - 1993-2012
    • Center for Disease Control (CDC), Progress toward elimination of onchocerciasis in the americas - 1993-2012. MMWR Morb.Mortal.Wkly.Rep 62 (2013), 405–408.
    • (2013) MMWR Morb.Mortal.Wkly.Rep , vol.62 , pp. 405-408
    • Center for Disease Control (CDC)1
  • 49
    • 84920155954 scopus 로고    scopus 로고
    • Elimination of African onchocerciasis: modeling the impact of increasing the frequency of ivermectin mass treatment
    • Coffeng, L.E., Stolk, W.A., Hoerauf, A., Habbema, D., Bakker, R., Hopkins, A.D., de Vlas, S.J., Elimination of African onchocerciasis: modeling the impact of increasing the frequency of ivermectin mass treatment. PLoS.One, 9, 2014, e115886.
    • (2014) PLoS.One , vol.9 , pp. e115886
    • Coffeng, L.E.1    Stolk, W.A.2    Hoerauf, A.3    Habbema, D.4    Bakker, R.5    Hopkins, A.D.6    de Vlas, S.J.7
  • 52
    • 77950611794 scopus 로고    scopus 로고
    • Accelerating drug development and approval
    • Cole, P., Accelerating drug development and approval. Drug News Perspect. 23 (2010), 37–47.
    • (2010) Drug News Perspect. , vol.23 , pp. 37-47
    • Cole, P.1
  • 53
    • 38849155626 scopus 로고    scopus 로고
    • Research and Development in the Pharmaceutical Industry
    • Pub. No 2589
    • Congress of the United States - Congressional Budget Office, Research and Development in the Pharmaceutical Industry. 2006 Pub. No 2589 http://www.cbo.gov/ftpdocs/76xx/doc7615/10-02-DrugR-D.pdf.
    • (2006)
    • Congress of the United States - Congressional Budget Office1
  • 58
    • 0038101035 scopus 로고    scopus 로고
    • Final report of the conference on the eradicability of Onchocerciasis
    • Dadzie, Y., Neira, M., Hopkins, D., Final report of the conference on the eradicability of Onchocerciasis. Filaria. J., 2, 2003, 2.
    • (2003) Filaria. J. , vol.2 , pp. 2
    • Dadzie, Y.1    Neira, M.2    Hopkins, D.3
  • 59
    • 33644776503 scopus 로고    scopus 로고
    • Assessment of microfilarial loads in the skin of onchocerciasis patients after treatment with different regimens of doxycycline plus ivermectin
    • Debrah, A.Y., Mand, S., Marfo-Debrekyei, Y., Larbi, J., Adjei, O., Hoerauf, A., Assessment of microfilarial loads in the skin of onchocerciasis patients after treatment with different regimens of doxycycline plus ivermectin. Filaria. J., 5, 2006, 1.
    • (2006) Filaria. J. , vol.5 , pp. 1
    • Debrah, A.Y.1    Mand, S.2    Marfo-Debrekyei, Y.3    Larbi, J.4    Adjei, O.5    Hoerauf, A.6
  • 64
    • 0037374498 scopus 로고    scopus 로고
    • The price of innovation: new estimates of drug development costs
    • Dimasi, J.A., Hansen, R.W., Grabowski, H.G., The price of innovation: new estimates of drug development costs. J.Health Econ. 22 (2003), 151–185.
    • (2003) J.Health Econ. , vol.22 , pp. 151-185
    • Dimasi, J.A.1    Hansen, R.W.2    Grabowski, H.G.3
  • 66
    • 0025732019 scopus 로고
    • Observations and reflections on the immature stages of Onchocerca volvulus in the human host
    • Duke, B.O., Observations and reflections on the immature stages of Onchocerca volvulus in the human host. Ann. Trop. Med. Parasitol. 85 (1991), 103–110.
    • (1991) Ann. Trop. Med. Parasitol. , vol.85 , pp. 103-110
    • Duke, B.O.1
  • 67
    • 84874278208 scopus 로고    scopus 로고
    • New advancement in anthelmintic drugs in veterinary medicine
    • Epe, C., Kaminsky, R., New advancement in anthelmintic drugs in veterinary medicine. Trends Parasitol. 29 (2013), 129–134.
    • (2013) Trends Parasitol. , vol.29 , pp. 129-134
    • Epe, C.1    Kaminsky, R.2
  • 69
    • 84862688087 scopus 로고    scopus 로고
    • The FDA's Drug Review Process: Ensuring Drugs Are Safe and Effective
    • Food and Drug Administration of the United States of America, The FDA's Drug Review Process: Ensuring Drugs Are Safe and Effective. 2012 http://www.fda.gov/drugs/resourcesforyou/consumers/ucm143534.htm.
    • (2012)
    • Food and Drug Administration of the United States of America1
  • 70
    • 0021826592 scopus 로고
    • The Mazzotti reaction following treatment of onchocerciasis with diethylcarbamazine: clinical severity as a function of infection intensity
    • Francis, H., Awadzi, K., Ottesen, E.A., The Mazzotti reaction following treatment of onchocerciasis with diethylcarbamazine: clinical severity as a function of infection intensity. Am. J. Trop. Med. Hyg. 34 (1985), 529–536.
    • (1985) Am. J. Trop. Med. Hyg. , vol.34 , pp. 529-536
    • Francis, H.1    Awadzi, K.2    Ottesen, E.A.3
  • 71
    • 0023607247 scopus 로고
    • The chemotherapy of onchocerciasis. XII. The prediction of microfilarial loads in patients with onchocerciasis after treatment with diethylcarbamazine in northern Ghana
    • Fulford, A.J., Macfarlane, S.B., Awadzi, K., Bell, D.R., Gilles, H.M., The chemotherapy of onchocerciasis. XII. The prediction of microfilarial loads in patients with onchocerciasis after treatment with diethylcarbamazine in northern Ghana. Ann. Trop. Med. Parasitol. 81 (1987), 701–711.
    • (1987) Ann. Trop. Med. Parasitol. , vol.81 , pp. 701-711
    • Fulford, A.J.1    Macfarlane, S.B.2    Awadzi, K.3    Bell, D.R.4    Gilles, H.M.5
  • 72
    • 0030981519 scopus 로고    scopus 로고
    • Serious reactions after mass treatment of onchocerciasis with ivermectin in an area endemic for Loa loa infection
    • Gardon, J., Gardon-Wendel, N., Demanga, N., Kamgno, J., Chippaux, J.P., Boussinesq, M., Serious reactions after mass treatment of onchocerciasis with ivermectin in an area endemic for Loa loa infection. Lancet 350 (1997), 18–22.
    • (1997) Lancet , vol.350 , pp. 18-22
    • Gardon, J.1    Gardon-Wendel, N.2    Demanga, N.3    Kamgno, J.4    Chippaux, J.P.5    Boussinesq, M.6
  • 73
    • 0032149610 scopus 로고    scopus 로고
    • Preliminary results on the effect of tetracycline on the embryogenesis and symbiotic bacteria (Wolbachia) of Dirofilaria immitis. An update and discussion
    • Genchi, C., Sacchi, L., Bandi, C., Venco, L., Preliminary results on the effect of tetracycline on the embryogenesis and symbiotic bacteria (Wolbachia) of Dirofilaria immitis. An update and discussion. Parassitologia 40 (1998), 247–249.
    • (1998) Parassitologia , vol.40 , pp. 247-249
    • Genchi, C.1    Sacchi, L.2    Bandi, C.3    Venco, L.4
  • 77
    • 0036022148 scopus 로고    scopus 로고
    • Cyclooctadepsipeptides–a new class of anthelmintically active compounds
    • Harder, A., von Samson-Himmelstjerna, G., Cyclooctadepsipeptides–a new class of anthelmintically active compounds. Parasitol. Res. 88 (2002), 481–488.
    • (2002) Parasitol. Res. , vol.88 , pp. 481-488
    • Harder, A.1    von Samson-Himmelstjerna, G.2
  • 78
    • 13644251110 scopus 로고    scopus 로고
    • Programmatic and communication issues in relation to serious adverse events following ivermectin treatment in areas Co-endemic for onchocerciasis and loiasis
    • Haselow, N.J., Akame, J., Evini, C., Akongo, S., Programmatic and communication issues in relation to serious adverse events following ivermectin treatment in areas Co-endemic for onchocerciasis and loiasis. Filaria. J., 2(Suppl. 1), 2003, S10.
    • (2003) Filaria. J. , vol.2 , pp. S10
    • Haselow, N.J.1    Akame, J.2    Evini, C.3    Akongo, S.4
  • 80
    • 0035810631 scopus 로고    scopus 로고
    • Depletion of wolbachia endobacteria in Onchocerca volvulus by doxycycline and microfilaridermia after ivermectin treatment
    • Hoerauf, A., Mand, S., Adjei, O., Fleischer, B., Buttner, D.W., Depletion of wolbachia endobacteria in Onchocerca volvulus by doxycycline and microfilaridermia after ivermectin treatment. Lancet 357 (2001), 1415–1416.
    • (2001) Lancet , vol.357 , pp. 1415-1416
    • Hoerauf, A.1    Mand, S.2    Adjei, O.3    Fleischer, B.4    Buttner, D.W.5
  • 81
    • 0037388065 scopus 로고    scopus 로고
    • Doxycycline in the treatment of human onchocerciasis: kinetics of Wolbachia endobacteria reduction and of inhibition of embryogenesis in female Onchocerca worms
    • Hoerauf, A., Mand, S., Volkmann, L., Buttner, M., Marfo-Debrekyei, Y., Taylor, M., Adjei, O., Buttner, D.W., Doxycycline in the treatment of human onchocerciasis: kinetics of Wolbachia endobacteria reduction and of inhibition of embryogenesis in female Onchocerca worms. Microbes. Infect. 5 (2003), 261–273.
    • (2003) Microbes. Infect. , vol.5 , pp. 261-273
    • Hoerauf, A.1    Mand, S.2    Volkmann, L.3    Buttner, M.4    Marfo-Debrekyei, Y.5    Taylor, M.6    Adjei, O.7    Buttner, D.W.8
  • 88
    • 85006471820 scopus 로고    scopus 로고
    • IFPMA Presentation to WHO Expert Working Group on Funding R&D for Diseases of the Developing World
    • (accessed 15.01.16.)
    • International Federation of Pharmaceutical Manufacturers & Associations, IFPMA Presentation to WHO Expert Working Group on Funding R&D for Diseases of the Developing World. 2009 (accessed 15.01.16.) www.who.int/phi/IFPMA_FundingR&D_Jan09.ppt.
    • (2009)
    • International Federation of Pharmaceutical Manufacturers & Associations1
  • 90
    • 84962361031 scopus 로고    scopus 로고
    • Effect of two or six doses 800 mg of albendazole every two months on loa loa microfilaraemia: a double blind, randomized, placebo-controlled trial
    • Kamgno, J., Nguipdop-Djomo, P., Gounoue, R., Tejiokem, M., Kuesel, A.C., Effect of two or six doses 800 mg of albendazole every two months on loa loa microfilaraemia: a double blind, randomized, placebo-controlled trial. PLoS.Negl. Trop. Dis., 10, 2016, e0004492.
    • (2016) PLoS.Negl. Trop. Dis. , vol.10 , pp. e0004492
    • Kamgno, J.1    Nguipdop-Djomo, P.2    Gounoue, R.3    Tejiokem, M.4    Kuesel, A.C.5
  • 91
    • 85006394750 scopus 로고    scopus 로고
    • Opthalmological findings from a study comparing the effect of a single dose of 150 microgram/kg ivermectin and of 8 mg moxidectin on microfilariae levels in Onchocerca volvulus infections
    • Kanza, E., Nyathirombo, A., Larbelee, J., Addy, E.T., Bakajika, D.K., Howard, H., Vaillant, M., Olliaro, P., Halleux, C.M., Kuesel, A.C., Opthalmological findings from a study comparing the effect of a single dose of 150 microgram/kg ivermectin and of 8 mg moxidectin on microfilariae levels in Onchocerca volvulus infections. Am. J. Trop. Med. Hyg., 89(Suppl. l), 2013, 79.
    • (2013) Am. J. Trop. Med. Hyg. , vol.89 , pp. 79
    • Kanza, E.1    Nyathirombo, A.2    Larbelee, J.3    Addy, E.T.4    Bakajika, D.K.5    Howard, H.6    Vaillant, M.7    Olliaro, P.8    Halleux, C.M.9    Kuesel, A.C.10
  • 92
    • 84945290539 scopus 로고    scopus 로고
    • Experience with the priority review voucher program for drug development
    • Kesselheim, A.S., Maggs, L.R., Sarpatwari, A., Experience with the priority review voucher program for drug development. JAMA 314 (2015), 1687–1688.
    • (2015) JAMA , vol.314 , pp. 1687-1688
    • Kesselheim, A.S.1    Maggs, L.R.2    Sarpatwari, A.3
  • 93
    • 4344645978 scopus 로고    scopus 로고
    • Can the pharmaceutical industry reduce attrition rates?
    • Kola, I., Landis, J., Can the pharmaceutical industry reduce attrition rates?. Nat.Rev. Drug Discov. 3 (2004), 711–715.
    • (2004) Nat.Rev. Drug Discov. , vol.3 , pp. 711-715
    • Kola, I.1    Landis, J.2
  • 98
    • 0017727943 scopus 로고
    • Intracytoplasmic bacteria in Onchocerca volvulus
    • Kozek, W.J., Marroquin, H.F., Intracytoplasmic bacteria in Onchocerca volvulus. Am. J. Trop. Med. Hyg. 26 (1977), 663–678.
    • (1977) Am. J. Trop. Med. Hyg. , vol.26 , pp. 663-678
    • Kozek, W.J.1    Marroquin, H.F.2
  • 103
    • 84905238699 scopus 로고    scopus 로고
    • In vivo preliminary investigations of the effects of the benzimidazole anthelmintic drug flubendazole on rat embryos and fetuses
    • Longo, M., Zanoncelli, S., Messina, M., Scandale, I., Mackenzie, C., Geary, T., Marsh, K., Lindley, D., Mazue, G., In vivo preliminary investigations of the effects of the benzimidazole anthelmintic drug flubendazole on rat embryos and fetuses. Reprod. Toxicol. 49C (2014), 33–42.
    • (2014) Reprod. Toxicol. , vol.49C , pp. 33-42
    • Longo, M.1    Zanoncelli, S.2    Messina, M.3    Scandale, I.4    Mackenzie, C.5    Geary, T.6    Marsh, K.7    Lindley, D.8    Mazue, G.9
  • 104
    • 84901749338 scopus 로고    scopus 로고
    • Interruption of infection transmission in the onchocerciasis focus of Ecuador leading to the cessation of ivermectin distribution
    • Lovato, R., Guevara, A., Guderian, R., Proano, R., Unnasch, T., Criollo, H., Hassan, H.K., Mackenzie, C.D., Interruption of infection transmission in the onchocerciasis focus of Ecuador leading to the cessation of ivermectin distribution. PLoS.Negl. Trop. Dis., 8, 2014, e2821.
    • (2014) PLoS.Negl. Trop. Dis. , vol.8 , pp. e2821
    • Lovato, R.1    Guevara, A.2    Guderian, R.3    Proano, R.4    Unnasch, T.5    Criollo, H.6    Hassan, H.K.7    Mackenzie, C.D.8
  • 106
    • 79957608338 scopus 로고    scopus 로고
    • Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs
    • Mackenzie, C.D., Geary, T.G., Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs. Expert. Rev. Anti. Infect. Ther. 9 (2011), 497–501.
    • (2011) Expert. Rev. Anti. Infect. Ther. , vol.9 , pp. 497-501
    • Mackenzie, C.D.1    Geary, T.G.2
  • 107
    • 26844460047 scopus 로고    scopus 로고
    • Possible pathogenic pathways in the adverse clinical events seen following ivermectin administration to onchocerciasis patients
    • Mackenzie, C.D., Geary, T.G., Gerlach, J.A., Possible pathogenic pathways in the adverse clinical events seen following ivermectin administration to onchocerciasis patients. Filaria. J., 2(Suppl. 1), 2003, S5.
    • (2003) Filaria. J. , vol.2 , pp. S5
    • Mackenzie, C.D.1    Geary, T.G.2    Gerlach, J.A.3
  • 109
    • 26844462535 scopus 로고    scopus 로고
    • Recommendations for the Treatment of Onchocerciasis with Mectizan in Areas Co-endemic for Onchocerciasis and Loiasis
    • http://www.mectizan.org/key-mectizan-expert-committee-recommendations
    • Mectizan Expert Committee and APOC Technical Consultative Committee, Recommendations for the Treatment of Onchocerciasis with Mectizan in Areas Co-endemic for Onchocerciasis and Loiasis. 2004 http://www.who.int/apoc/publications/recommendations/en/index.html http://www.mectizan.org/key-mectizan-expert-committee-recommendations.
    • (2004)
    • Mectizan Expert Committee and APOC Technical Consultative Committee1
  • 111
    • 84904519630 scopus 로고    scopus 로고
    • The geographic distribution of Onchocerciasis in the 20 participating countries of the African programme for Onchocerciasis control: (1) priority areas for ivermectin treatment
    • Noma, M., Zoure, H.G., Tekle, A.H., Enyong, P.A., Nwoke, B.E., Remme, J.H., The geographic distribution of Onchocerciasis in the 20 participating countries of the African programme for Onchocerciasis control: (1) priority areas for ivermectin treatment. Parasit. Vectors, 7, 2014, 325.
    • (2014) Parasit. Vectors , vol.7 , pp. 325
    • Noma, M.1    Zoure, H.G.2    Tekle, A.H.3    Enyong, P.A.4    Nwoke, B.E.5    Remme, J.H.6
  • 112
    • 0022494813 scopus 로고
    • Loa loa infection in temporary residents of endemic regions: recognition of a hyperresponsive syndrome with characteristic clinical manifestations
    • Nutman, T.B., Miller, K.D., Mulligan, M., Ottesen, E.A., Loa loa infection in temporary residents of endemic regions: recognition of a hyperresponsive syndrome with characteristic clinical manifestations. J. Infect. Dis. 154 (1986), 10–18.
    • (1986) J. Infect. Dis. , vol.154 , pp. 10-18
    • Nutman, T.B.1    Miller, K.D.2    Mulligan, M.3    Ottesen, E.A.4
  • 115
    • 85006455190 scopus 로고    scopus 로고
    • Efficacy of a single oral dose of 8 mg Moxidectin vs. 150 ug/kg ivermectin in onchocerca volvulus infection: results of a randomized, double-blind single dose phase 3 study in areas without mass treatment with ivermectin in Liberia, Ghana and DRC
    • Opoku, N.O., Bakajika, D.K., Kanza, E., Howard, H., Attah, S.K., Tchatchu, J.-P.L., Kataliko, K., Kpawor, M., Vaillant, M., Halleux, C.M., Olliaro, P.L., Kuesel, A.C., Efficacy of a single oral dose of 8 mg Moxidectin vs. 150 ug/kg ivermectin in onchocerca volvulus infection: results of a randomized, double-blind single dose phase 3 study in areas without mass treatment with ivermectin in Liberia, Ghana and DRC. Trop.Med.Int Health, 18(Suppl. 1), 2013, 58.
    • (2013) Trop.Med.Int Health , vol.18 , pp. 58
    • Opoku, N.O.1    Bakajika, D.K.2    Kanza, E.3    Howard, H.4    Attah, S.K.5    Tchatchu, J.-P.L.6    Kataliko, K.7    Kpawor, M.8    Vaillant, M.9    Halleux, C.M.10    Olliaro, P.L.11    Kuesel, A.C.12
  • 117
    • 34250196496 scopus 로고    scopus 로고
    • Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: a two-phase epidemiological study
    • Osei-Atweneboana, M.Y., Eng, J.K., Boakye, D.A., Gyapong, J.O., Prichard, R.K., Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: a two-phase epidemiological study. Lancet 369 (2007), 2021–2029.
    • (2007) Lancet , vol.369 , pp. 2021-2029
    • Osei-Atweneboana, M.Y.1    Eng, J.K.2    Boakye, D.A.3    Gyapong, J.O.4    Prichard, R.K.5
  • 120
    • 84929104373 scopus 로고    scopus 로고
    • The impact of two semiannual treatments with albendazole alone on lymphatic filariasis and soil-transmitted helminth infections: a community-based study in the Republic of Congo
    • Pion, S.D., Chesnais, C.B., Bopda, J., Louya, F., Fischer, P.U., Majewski, A.C., Weil, G.J., Boussinesq, M., Missamou, F., The impact of two semiannual treatments with albendazole alone on lymphatic filariasis and soil-transmitted helminth infections: a community-based study in the Republic of Congo. Am. J. Trop. Med. Hyg. 92 (2015), 959–966.
    • (2015) Am. J. Trop. Med. Hyg. , vol.92 , pp. 959-966
    • Pion, S.D.1    Chesnais, C.B.2    Bopda, J.3    Louya, F.4    Fischer, P.U.5    Majewski, A.C.6    Weil, G.J.7    Boussinesq, M.8    Missamou, F.9
  • 121
    • 80054033652 scopus 로고    scopus 로고
    • Individual host factors associated with Onchocerca volvulus microfilarial densities 15, 80 and 180 days after a first dose of ivermectin
    • Pion, S.D., Grout, L., Kamgno, J., Nana-Djeunga, H., Boussinesq, M., Individual host factors associated with Onchocerca volvulus microfilarial densities 15, 80 and 180 days after a first dose of ivermectin. Acta Trop. 120:Suppl. 1 (2011), S91–S99.
    • (2011) Acta Trop. , vol.120 , pp. S91-S99
    • Pion, S.D.1    Grout, L.2    Kamgno, J.3    Nana-Djeunga, H.4    Boussinesq, M.5
  • 122
    • 84874786546 scopus 로고    scopus 로고
    • Dynamics of Onchocerca volvulus microfilarial densities after ivermectin treatment in an ivermectin-naive and a multiply treated population from Cameroon
    • Pion, S.D., Nana-Djeunga, H.C., Kamgno, J., Tendongfor, N., Wanji, S., Njiokou, F., Prichard, R.K., Boussinesq, M., Dynamics of Onchocerca volvulus microfilarial densities after ivermectin treatment in an ivermectin-naive and a multiply treated population from Cameroon. PLoS.Negl. Trop. Dis., 7, 2013, e2084.
    • (2013) PLoS.Negl. Trop. Dis. , vol.7 , pp. e2084
    • Pion, S.D.1    Nana-Djeunga, H.C.2    Kamgno, J.3    Tendongfor, N.4    Wanji, S.5    Njiokou, F.6    Prichard, R.K.7    Boussinesq, M.8
  • 124
    • 0026023124 scopus 로고
    • The reproductive lifespan of Onchocerca volvulus in West African savanna
    • Plaisier, A.P., van Oortmarssen, G.J., Remme, J., Habbema, J.D., The reproductive lifespan of Onchocerca volvulus in West African savanna. Acta Trop. 48 (1991), 271–284.
    • (1991) Acta Trop. , vol.48 , pp. 271-284
    • Plaisier, A.P.1    van Oortmarssen, G.J.2    Remme, J.3    Habbema, J.D.4
  • 126
    • 0023039260 scopus 로고
    • A force-of-infection model for onchocerciasis and its applications in the epidemiological evaluation of the Onchocerciasis Control Programme in the Volta River basin area
    • Remme, J., Ba, O., Dadzie, K.Y., Karam, M., A force-of-infection model for onchocerciasis and its applications in the epidemiological evaluation of the Onchocerciasis Control Programme in the Volta River basin area. Bull. World Health Organ 64 (1986), 667–681.
    • (1986) Bull. World Health Organ , vol.64 , pp. 667-681
    • Remme, J.1    Ba, O.2    Dadzie, K.Y.3    Karam, M.4
  • 127
    • 0024445534 scopus 로고
    • A community trial of ivermectin in the onchocerciasis focus of Asubende, Ghana. I. Effect on the microfilarial reservoir and the transmission of Onchocerca volvulus
    • Remme, J., Baker, R.H., DeSole, G., Dadzie, K.Y., Walsh, J.F., Adams, M.A., Alley, E.S., Avissey, H.S., A community trial of ivermectin in the onchocerciasis focus of Asubende, Ghana. I. Effect on the microfilarial reservoir and the transmission of Onchocerca volvulus. Trop. Med. Parasitol. 40 (1989), 367–374.
    • (1989) Trop. Med. Parasitol. , vol.40 , pp. 367-374
    • Remme, J.1    Baker, R.H.2    DeSole, G.3    Dadzie, K.Y.4    Walsh, J.F.5    Adams, M.A.6    Alley, E.S.7    Avissey, H.S.8
  • 128
    • 0025350357 scopus 로고
    • The predicted and observed decline in onchocerciasis infection during 14 years of successful control of Simulium spp. in west Africa
    • Remme, J., DeSole, G., van Oortmarssen, G.J., The predicted and observed decline in onchocerciasis infection during 14 years of successful control of Simulium spp. in west Africa. Bull. World Health Organ 68 (1990), 331–339.
    • (1990) Bull. World Health Organ , vol.68 , pp. 331-339
    • Remme, J.1    DeSole, G.2    van Oortmarssen, G.J.3
  • 129
    • 1342322716 scopus 로고    scopus 로고
    • Research for control: the onchocerciasis experience
    • Remme, J.H., Research for control: the onchocerciasis experience. Trop.Med.Int. Health 9 (2004), 243–254.
    • (2004) Trop.Med.Int. Health , vol.9 , pp. 243-254
    • Remme, J.H.1
  • 132
    • 77956562112 scopus 로고    scopus 로고
    • Introduction of European priority review vouchers to encourage development of new medicines for neglected diseases
    • Ridley, D.B., Sanchez, A.C., Introduction of European priority review vouchers to encourage development of new medicines for neglected diseases. Lancet 376 (2010), 922–927.
    • (2010) Lancet , vol.376 , pp. 922-927
    • Ridley, D.B.1    Sanchez, A.C.2
  • 133
    • 84865967881 scopus 로고    scopus 로고
    • The impact of the US priority review voucher on private-sector investment in global health research and development
    • Robertson, A.S., Stefanakis, R., Joseph, D., Moree, M., The impact of the US priority review voucher on private-sector investment in global health research and development. PLoS.Negl. Trop. Dis., 6, 2012, e1750.
    • (2012) PLoS.Negl. Trop. Dis. , vol.6 , pp. e1750
    • Robertson, A.S.1    Stefanakis, R.2    Joseph, D.3    Moree, M.4
  • 136
    • 84901391699 scopus 로고    scopus 로고
    • The use of the United States FDA programs as a strategy to advance the development of drug products for neglected tropical diseases
    • Sachs-Barrable, K., Conway, J., Gershkovich, P., Ibrahim, F., Wasan, K.M., The use of the United States FDA programs as a strategy to advance the development of drug products for neglected tropical diseases. Drug Dev. Ind. Pharm. 40 (2014), 1429–1434.
    • (2014) Drug Dev. Ind. Pharm. , vol.40 , pp. 1429-1434
    • Sachs-Barrable, K.1    Conway, J.2    Gershkovich, P.3    Ibrahim, F.4    Wasan, K.M.5
  • 137
    • 42449109752 scopus 로고    scopus 로고
    • Report of a scientific working group on serious adverse events following Mectizan(R) treatment of onchocerciasis in loa loa endemic areas
    • Scientific Working Group on Serious Adverse Events in Loa Loa endemic areas, Report of a scientific working group on serious adverse events following Mectizan(R) treatment of onchocerciasis in loa loa endemic areas. Filaria. J., 2(Suppl. 1), 2003, S2, 10.1186/1475-2883-2-S1-S2.
    • (2003) Filaria. J. , vol.2 , pp. S2
    • Scientific Working Group on Serious Adverse Events in Loa Loa endemic areas1
  • 139
    • 70350342535 scopus 로고    scopus 로고
    • In defence of priority review vouchers
    • Sonderholm, J., In defence of priority review vouchers. Bioethics 23 (2009), 413–420.
    • (2009) Bioethics , vol.23 , pp. 413-420
    • Sonderholm, J.1
  • 141
    • 84945187293 scopus 로고    scopus 로고
    • Required duration of mass ivermectin treatment for onchocerciasis elimination in Africa: a comparative modelling analysis
    • Stolk, W.A., Walker, M., Coffeng, L.E., Basanez, M.G., de Vlas, S.J., Required duration of mass ivermectin treatment for onchocerciasis elimination in Africa: a comparative modelling analysis. Parasit. Vectors, 8, 2015, 552.
    • (2015) Parasit. Vectors , vol.8 , pp. 552
    • Stolk, W.A.1    Walker, M.2    Coffeng, L.E.3    Basanez, M.G.4    de Vlas, S.J.5
  • 142
    • 0029856573 scopus 로고    scopus 로고
    • Onchocerca volvulus and O. lienalis: the microfilaricidal activity of moxidectin compared with that of ivermectin in vitro and in vivo
    • Tagboto, S.K., Townson, S., Onchocerca volvulus and O. lienalis: the microfilaricidal activity of moxidectin compared with that of ivermectin in vitro and in vivo. Ann. Trop. Med. Parasitol. 90 (1996), 497–505.
    • (1996) Ann. Trop. Med. Parasitol. , vol.90 , pp. 497-505
    • Tagboto, S.K.1    Townson, S.2
  • 143
    • 79960131845 scopus 로고    scopus 로고
    • Onchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment
    • Tamarozzi, F., Halliday, A., Gentil, K., Hoerauf, A., Pearlman, E., Taylor, M.J., Onchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment. Clin. Microbiol. Rev. 24 (2011), 459–468.
    • (2011) Clin. Microbiol. Rev. , vol.24 , pp. 459-468
    • Tamarozzi, F.1    Halliday, A.2    Gentil, K.3    Hoerauf, A.4    Pearlman, E.5    Taylor, M.J.6
  • 144
    • 0034191876 scopus 로고    scopus 로고
    • Wolbachia bacteria of filarial nematodes: a target for control?
    • Taylor, M.J., Bandi, C., Hoerauf, A.M., Lazdins, J., Wolbachia bacteria of filarial nematodes: a target for control?. Parasitol. Today 16 (2000), 179–180.
    • (2000) Parasitol. Today , vol.16 , pp. 179-180
    • Taylor, M.J.1    Bandi, C.2    Hoerauf, A.M.3    Lazdins, J.4
  • 145
    • 84891846369 scopus 로고    scopus 로고
    • Anti-Wolbachia drug discovery and development: safe macrofilaricides for onchocerciasis and lymphatic filariasis
    • Taylor, M.J., Hoerauf, A., Townson, S., Slatko, B.E., Ward, S.A., Anti-Wolbachia drug discovery and development: safe macrofilaricides for onchocerciasis and lymphatic filariasis. Parasitology 141 (2014), 119–127.
    • (2014) Parasitology , vol.141 , pp. 119-127
    • Taylor, M.J.1    Hoerauf, A.2    Townson, S.3    Slatko, B.E.4    Ward, S.A.5
  • 146
    • 84856564960 scopus 로고    scopus 로고
    • Impact of long-term treatment of onchocerciasis with ivermectin in Kaduna State, Nigeria: first evidence of the potential for elimination in the operational area of the African Programme for Onchocerciasis Control
    • Tekle, A.H., Elhassan, E., Isiyaku, S., Amazigo, U.V., Bush, S., Noma, M., Cousens, S., Abiose, A., Remme, J.H., Impact of long-term treatment of onchocerciasis with ivermectin in Kaduna State, Nigeria: first evidence of the potential for elimination in the operational area of the African Programme for Onchocerciasis Control. Parasit. Vectors, 5, 2012, 28.
    • (2012) Parasit. Vectors , vol.5 , pp. 28
    • Tekle, A.H.1    Elhassan, E.2    Isiyaku, S.3    Amazigo, U.V.4    Bush, S.5    Noma, M.6    Cousens, S.7    Abiose, A.8    Remme, J.H.9
  • 147
    • 51149120446 scopus 로고    scopus 로고
    • Activity of the cyclooctadepsipeptide emodepside against onchocerca gutturosa, onchocerca lienalis and brugia pahangi
    • Townson, S., Freeman, A., Harris, A., Harder, A., Activity of the cyclooctadepsipeptide emodepside against onchocerca gutturosa, onchocerca lienalis and brugia pahangi. Am. J. Trop. Med. Hyg., 73, 2005, 93.
    • (2005) Am. J. Trop. Med. Hyg. , vol.73 , pp. 93
    • Townson, S.1    Freeman, A.2    Harris, A.3    Harder, A.4
  • 150
    • 84926681814 scopus 로고    scopus 로고
    • The potential impact of moxidectin on onchocerciasis elimination in Africa: an economic evaluation based on the Phase II clinical trial data
    • Turner, H.C., Walker, M., Attah, S.K., Opoku, N.O., Awadzi, K., Kuesel, A.C., Basanez, M.G., The potential impact of moxidectin on onchocerciasis elimination in Africa: an economic evaluation based on the Phase II clinical trial data. Parasit. Vectors, 8, 2015, 167.
    • (2015) Parasit. Vectors , vol.8 , pp. 167
    • Turner, H.C.1    Walker, M.2    Attah, S.K.3    Opoku, N.O.4    Awadzi, K.5    Kuesel, A.C.6    Basanez, M.G.7
  • 151
    • 84902118155 scopus 로고    scopus 로고
    • Modelling the impact of ivermectin on River Blindness and its burden of morbidity and mortality in African Savannah: EpiOncho projections
    • Turner, H.C., Walker, M., Churcher, T.S., Basanez, M.G., Modelling the impact of ivermectin on River Blindness and its burden of morbidity and mortality in African Savannah: EpiOncho projections. Parasit. Vectors, 7, 2014, 241.
    • (2014) Parasit. Vectors , vol.7 , pp. 241
    • Turner, H.C.1    Walker, M.2    Churcher, T.S.3    Basanez, M.G.4
  • 153
    • 84966659014 scopus 로고    scopus 로고
    • Genotoxicity of flubendazole and its metabolites in vitro and the impact of a new formulation on in vivo aneugenicity
    • (Epub Oct 6 2015)
    • Tweats, D.J., Johnson, G.E., Scandale, I., Whitwell, J., Evans, D.B., Genotoxicity of flubendazole and its metabolites in vitro and the impact of a new formulation on in vivo aneugenicity. Mutagenesis 31 (2016), 309–321, 10.1093/mutage/gev070 (Epub Oct 6 2015).
    • (2016) Mutagenesis , vol.31 , pp. 309-321
    • Tweats, D.J.1    Johnson, G.E.2    Scandale, I.3    Whitwell, J.4    Evans, D.B.5
  • 154
    • 0041757704 scopus 로고    scopus 로고
    • Loa loa encephalopathy temporally related to ivermectin administration reported from onchocerciasis mass treatment programs from 1989 to 2001: implications for the future
    • Twum-Danso, N.A., Loa loa encephalopathy temporally related to ivermectin administration reported from onchocerciasis mass treatment programs from 1989 to 2001: implications for the future. Filaria. J., 2(Suppl. 1), 2003, S7.
    • (2003) Filaria. J. , vol.2 , pp. S7
    • Twum-Danso, N.A.1
  • 155
    • 0042759615 scopus 로고    scopus 로고
    • Serious adverse events following treatment with ivermectin for onchocerciasis control: a review of reported cases
    • Twum-Danso, N.A., Serious adverse events following treatment with ivermectin for onchocerciasis control: a review of reported cases. Filaria. J., 2(Suppl. 1), 2003, S3.
    • (2003) Filaria. J. , vol.2 , pp. S3
    • Twum-Danso, N.A.1
  • 156
    • 0042736852 scopus 로고    scopus 로고
    • Variation in incidence of serious adverse events after onchocerciasis treatment with ivermectin in areas of Cameroon co-endemic for loiasis
    • Twum-Danso, N.A., Meredith, S.E., Variation in incidence of serious adverse events after onchocerciasis treatment with ivermectin in areas of Cameroon co-endemic for loiasis. Trop.Med.Int Health 8 (2003), 820–831.
    • (2003) Trop.Med.Int Health , vol.8 , pp. 820-831
    • Twum-Danso, N.A.1    Meredith, S.E.2
  • 157
    • 15944380075 scopus 로고    scopus 로고
    • Efficacy of two cyclooctadepsipeptides, PF1022A and emodepside, against anthelmintic-resistant nematodes in sheep and cattle
    • von Samson-Himmelstjerna, G., Harder, A., Sangster, N.C., Coles, G.C., Efficacy of two cyclooctadepsipeptides, PF1022A and emodepside, against anthelmintic-resistant nematodes in sheep and cattle. Parasitology 130 (2005), 343–347.
    • (2005) Parasitology , vol.130 , pp. 343-347
    • von Samson-Himmelstjerna, G.1    Harder, A.2    Sangster, N.C.3    Coles, G.C.4
  • 158
    • 84926646741 scopus 로고    scopus 로고
    • Therapeutic efficacy and macrofilaricidal activity of doxycycline for the treatment of river blindness
    • Walker, M., Specht, S., Churcher, T.S., Hoerauf, A., Taylor, M.J., Basanez, M.G., Therapeutic efficacy and macrofilaricidal activity of doxycycline for the treatment of river blindness. Clin. Infect. Dis. 60 (2015), 1199–1207.
    • (2015) Clin. Infect. Dis. , vol.60 , pp. 1199-1207
    • Walker, M.1    Specht, S.2    Churcher, T.S.3    Hoerauf, A.4    Taylor, M.J.5    Basanez, M.G.6
  • 160
    • 84885012883 scopus 로고    scopus 로고
    • River blindness eliminated in Colombia
    • West, S., Munoz, B., Sommer, A., River blindness eliminated in Colombia. Ophthalmic Epidemiol. 20 (2013), 258–259.
    • (2013) Ophthalmic Epidemiol. , vol.20 , pp. 258-259
    • West, S.1    Munoz, B.2    Sommer, A.3
  • 161
    • 85006464335 scopus 로고    scopus 로고
    • Tropical Disease Research: Progress 2003-2004WHO/TDR (TDR/GEN/05.1
    • (accessed 15.01.16.), Geneva
    • WHO/TDR, Tropical Disease Research: Progress 2003-2004WHO/TDR (TDR/GEN/05.1. 2005 http://www.who.int/tdr/publications/about-tdr/annual-reports/en/ (accessed 15.01.16.), Geneva.
    • (2005)
    • WHO/TDR1
  • 162
    • 0037282198 scopus 로고    scopus 로고
    • The effect of the anthelmintic emodepside at the neuromuscular junction of the parasitic nematode Ascaris suum
    • Willson, J., Amliwala, K., Harder, A., Holden-Dye, L., Walker, R.J., The effect of the anthelmintic emodepside at the neuromuscular junction of the parasitic nematode Ascaris suum. Parasitology 126 (2003), 79–86.
    • (2003) Parasitology , vol.126 , pp. 79-86
    • Willson, J.1    Amliwala, K.2    Harder, A.3    Holden-Dye, L.4    Walker, R.J.5
  • 163
    • 85006349289 scopus 로고
    • Onchocerciasis and its Control. Report of a WHO Expert Committee on Onchocerciasis ControlWorld Health Organization
    • World Health Organization, Onchocerciasis and its Control. Report of a WHO Expert Committee on Onchocerciasis ControlWorld Health Organization., 1995.
    • (1995)
    • World Health Organization1
  • 164
    • 84859003061 scopus 로고    scopus 로고
    • Accelerating Work to Overcome the Global Impact of Neglected Tropical Diseases. A Roadmap for Implementation (WHO/HTM/NTD/2012.1)World Health Organization
    • (Geneva)
    • World Health Organization, Accelerating Work to Overcome the Global Impact of Neglected Tropical Diseases. A Roadmap for Implementation (WHO/HTM/NTD/2012.1)World Health Organization. 2012 http://whqlibdoc.who.int/hq/2012/WHO_HTM_NTD_2012.1_eng.pdf (Geneva).
    • (2012)
    • World Health Organization1
  • 165
    • 84872157086 scopus 로고    scopus 로고
    • Provisional Strategy for Interruption Lymphatic Filariasis Transmission in Loiasis-endemic Countries. Report of the Meeting on Lymphatic Filariasis, Malaria and Integrated Vector Management, Accra, Ghana
    • March 2012
    • World Health Organization, Provisional Strategy for Interruption Lymphatic Filariasis Transmission in Loiasis-endemic Countries. Report of the Meeting on Lymphatic Filariasis, Malaria and Integrated Vector Management, Accra, Ghana., 2012 March 2012 http://www.who.int/iris/bitstream/10665/75139/3/WHO_HTM_NTD_PCT_2012.6_eng.pdf?u.
    • (2012)
    • World Health Organization1
  • 166
    • 84974564348 scopus 로고    scopus 로고
    • Guidelines for Stopping Mass Drug Administration and Verifying Elimination of Human Onchocerciasis: Criteria and Procedures
    • World Health Organization Geneva
    • World Health Organization, Guidelines for Stopping Mass Drug Administration and Verifying Elimination of Human Onchocerciasis: Criteria and Procedures. 2016, World Health Organization, Geneva.
    • (2016)
    • World Health Organization1
  • 168
    • 84904528181 scopus 로고    scopus 로고
    • The geographic distribution of onchocerciasis in the 20 participating countries of the African Programme for Onchocerciasis control: (2) pre-control endemicity levels and estimated number infected
    • Zoure, H.G., Noma, M., Tekle, A.H., Amazigo, U.V., Diggle, P.J., Giorgi, E., Remme, J.H., The geographic distribution of onchocerciasis in the 20 participating countries of the African Programme for Onchocerciasis control: (2) pre-control endemicity levels and estimated number infected. Parasit. Vectors, 7, 2014, 326.
    • (2014) Parasit. Vectors , vol.7 , pp. 326
    • Zoure, H.G.1    Noma, M.2    Tekle, A.H.3    Amazigo, U.V.4    Diggle, P.J.5    Giorgi, E.6    Remme, J.H.7
  • 169
    • 79959815095 scopus 로고    scopus 로고
    • The geographic distribution of Loa loa in Africa: results of large-scale implementation of the Rapid Assessment Procedure for Loiasis (RAPLOA)
    • Zoure, H.G., Wanji, S., Noma, M., Amazigo, U.V., Diggle, P.J., Tekle, A.H., Remme, J.H., The geographic distribution of Loa loa in Africa: results of large-scale implementation of the Rapid Assessment Procedure for Loiasis (RAPLOA). PLoS.Negl. Trop. Dis., 5, 2011, e1210.
    • (2011) PLoS.Negl. Trop. Dis. , vol.5 , pp. e1210
    • Zoure, H.G.1    Wanji, S.2    Noma, M.3    Amazigo, U.V.4    Diggle, P.J.5    Tekle, A.H.6    Remme, J.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.