메뉴 건너뛰기




Volumn 28, Issue 9, 2012, Pages 385-394

Anthelmintic cyclcooctadepsipeptides: Complex in structure and mode of action

Author keywords

Anthelmintic cyclcooctadepsipeptides; Emodepside; Lathrophilin; PF1022A; PF1022A synthesis; Rosellinia; SLO 1

Indexed keywords

CYCLCOOCTADEPSIPEPTIDE PF1022A; CYCLODEPSIPEPTIDE; EMODEPSIDE; UNCLASSIFIED DRUG;

EID: 84865187698     PISSN: 14714922     EISSN: 14715007     Source Type: Journal    
DOI: 10.1016/j.pt.2012.06.005     Document Type: Review
Times cited : (49)

References (102)
  • 1
    • 0036170245 scopus 로고    scopus 로고
    • Chemotherapeutic approaches to nematodes: current knowledge and outlook
    • Harder A. Chemotherapeutic approaches to nematodes: current knowledge and outlook. Parasitol. Res. 2002, 88:272-277.
    • (2002) Parasitol. Res. , vol.88 , pp. 272-277
    • Harder, A.1
  • 3
    • 34347394336 scopus 로고    scopus 로고
    • Mode of action of levamisole and pyrantel, anthelmintic resistance, E153 and Q57
    • Martin R.J., Robertson A.P. Mode of action of levamisole and pyrantel, anthelmintic resistance, E153 and Q57. Parasitology 2007, 134:1093-1104.
    • (2007) Parasitology , vol.134 , pp. 1093-1104
    • Martin, R.J.1    Robertson, A.P.2
  • 4
    • 77958126455 scopus 로고    scopus 로고
    • Monepantel allosterically activates DEG-3/DES-2 channels of the gastrointestinal nematode Haemonchus contortus
    • Rufener L., et al. Monepantel allosterically activates DEG-3/DES-2 channels of the gastrointestinal nematode Haemonchus contortus. Mol. Pharmacol. 2010, 78:895-902.
    • (2010) Mol. Pharmacol. , vol.78 , pp. 895-902
    • Rufener, L.1
  • 5
    • 40749099893 scopus 로고    scopus 로고
    • A new class of anthelmintics effective against drug-resistant nematodes
    • Kaminsky R., et al. A new class of anthelmintics effective against drug-resistant nematodes. Nature 2008, 452:176-180.
    • (2008) Nature , vol.452 , pp. 176-180
    • Kaminsky, R.1
  • 6
    • 42449084148 scopus 로고    scopus 로고
    • Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis
    • Keiser J., Utzinger J. Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis. JAMA 2008, 299:1937-1948.
    • (2008) JAMA , vol.299 , pp. 1937-1948
    • Keiser, J.1    Utzinger, J.2
  • 7
    • 13944283020 scopus 로고    scopus 로고
    • Satoshi Omura: in pursuit of nature's bounty
    • Crump A., Otoguro K. Satoshi Omura: in pursuit of nature's bounty. Trends Parasitol. 2005, 21:126-132.
    • (2005) Trends Parasitol. , vol.21 , pp. 126-132
    • Crump, A.1    Otoguro, K.2
  • 8
    • 80051775550 scopus 로고    scopus 로고
    • Progress and challenges in the discovery of macrofilaricidal drugs
    • Geary T.G., Mackenzie C.D. Progress and challenges in the discovery of macrofilaricidal drugs. Expert Rev. Anti Infect. Ther. 2011, 9:681-695.
    • (2011) Expert Rev. Anti Infect. Ther. , vol.9 , pp. 681-695
    • Geary, T.G.1    Mackenzie, C.D.2
  • 9
    • 77953669706 scopus 로고    scopus 로고
    • Field efficacy and safety of an oral formulation of the novel combination anthelmintic, derquantel-abamectin, in sheep in New Zealand
    • Little P.R., et al. Field efficacy and safety of an oral formulation of the novel combination anthelmintic, derquantel-abamectin, in sheep in New Zealand. N. Z. Vet. J. 2010, 58:121-129.
    • (2010) N. Z. Vet. J. , vol.58 , pp. 121-129
    • Little, P.R.1
  • 10
    • 4444328499 scopus 로고    scopus 로고
    • Drug resistance in veterinary helminths
    • Wolstenholme A.J., et al. Drug resistance in veterinary helminths. Trends Parasitol. 2004, 20:469-476.
    • (2004) Trends Parasitol. , vol.20 , pp. 469-476
    • Wolstenholme, A.J.1
  • 11
    • 59849129784 scopus 로고    scopus 로고
    • Monitoring the efficacy of ivermectin and albendazole against gastro intestinal nematodes of cattle in Northern Europe
    • Demeler J., et al. Monitoring the efficacy of ivermectin and albendazole against gastro intestinal nematodes of cattle in Northern Europe. Vet. Parasitol. 2009, 160:109-115.
    • (2009) Vet. Parasitol. , vol.160 , pp. 109-115
    • Demeler, J.1
  • 12
    • 0036746954 scopus 로고    scopus 로고
    • Anthelmintic resistance in nematodes of horses
    • Kaplan R.M. Anthelmintic resistance in nematodes of horses. Vet. Res. 2002, 33:491-507.
    • (2002) Vet. Res. , vol.33 , pp. 491-507
    • Kaplan, R.M.1
  • 13
    • 33846573834 scopus 로고    scopus 로고
    • Cases of reduced cyathostomin egg-reappearance period and failure of Parascaris equorum egg count reduction following ivermectin treatment as well as survey on pyrantel efficacy on German horse farms
    • von Samson-Himmelstjerna G., et al. Cases of reduced cyathostomin egg-reappearance period and failure of Parascaris equorum egg count reduction following ivermectin treatment as well as survey on pyrantel efficacy on German horse farms. Vet. Parasitol. 2007, 144:74-80.
    • (2007) Vet. Parasitol. , vol.144 , pp. 74-80
    • von Samson-Himmelstjerna, G.1
  • 14
    • 0026683249 scopus 로고
    • A new anthelmintic cyclodepsipeptide, PF1022A
    • Sasaki T., et al. A new anthelmintic cyclodepsipeptide, PF1022A. J. Antibiot. (Tokyo) 1992, 45:692-697.
    • (1992) J. Antibiot. (Tokyo) , vol.45 , pp. 692-697
    • Sasaki, T.1
  • 15
    • 3042837917 scopus 로고    scopus 로고
    • Taxonomic position of the fungus producing the anthelmintic PF1022 based on the 18S rRNA gene base sequence
    • Miyadoh S., et al. Taxonomic position of the fungus producing the anthelmintic PF1022 based on the 18S rRNA gene base sequence. Nippon Kingakukai Kaiho 2000, 41:183-188.
    • (2000) Nippon Kingakukai Kaiho , vol.41 , pp. 183-188
    • Miyadoh, S.1
  • 16
    • 84865192088 scopus 로고    scopus 로고
    • Meiji Seika Kaisha, Ltd., Japan. Process for producing cyclodepsipeptide compounds with microorganisms, PCT Int. Appl.
    • WO 9805655 A1 19980212, ref. CAN 128:179454
    • Ohyama, M. et al. Meiji Seika Kaisha, Ltd., Japan. Process for producing cyclodepsipeptide compounds with microorganisms, PCT Int. Appl., WO 9805655 A1 19980212, ref. CAN 128:179454.
    • Ohyama, M.1
  • 17
    • 0000834267 scopus 로고
    • Bassianolide - new insecticidal cyclodepsipeptide from Beauveria bassiana and Verticillium lecanii
    • Suzuki A., et al. Bassianolide - new insecticidal cyclodepsipeptide from Beauveria bassiana and Verticillium lecanii. Tetrahedron Lett. 1977, 18:2167-2170.
    • (1977) Tetrahedron Lett. , vol.18 , pp. 2167-2170
    • Suzuki, A.1
  • 18
    • 11144225918 scopus 로고    scopus 로고
    • Emodepside, a cyclo-octadepsipeptide anthelmintic with a novel mode of action
    • Amliwala K., et al. Emodepside, a cyclo-octadepsipeptide anthelmintic with a novel mode of action. Drugs Future 2004, 29:1015-1024.
    • (2004) Drugs Future , vol.29 , pp. 1015-1024
    • Amliwala, K.1
  • 19
    • 84865162950 scopus 로고    scopus 로고
    • Cyclooctadepsipeptides - an anthelmintically active class of compounds exhibiting a novel mode of action
    • Wiley-VCH, P.M. Selzer (Ed.)
    • Harder A., et al. Cyclooctadepsipeptides - an anthelmintically active class of compounds exhibiting a novel mode of action. Antiparasitic and Antibacterial Drug Discovery: From Molecular Targets to Drug Candidates 2009, 339-356. Wiley-VCH. P.M. Selzer (Ed.).
    • (2009) Antiparasitic and Antibacterial Drug Discovery: From Molecular Targets to Drug Candidates , pp. 339-356
    • Harder, A.1
  • 20
    • 0041331791 scopus 로고    scopus 로고
    • Cyclooctadepsipeptides - an anthelmintically active class of compounds exhibiting a novel mode of action
    • Harder A., et al. Cyclooctadepsipeptides - an anthelmintically active class of compounds exhibiting a novel mode of action. Int. J. Antimicrob. Agents 2003, 22:318-331.
    • (2003) Int. J. Antimicrob. Agents , vol.22 , pp. 318-331
    • Harder, A.1
  • 21
    • 0038195791 scopus 로고    scopus 로고
    • PF1022A and related cyclodepsipeptides - a novel class of anthelmintics
    • Scherkenbeck J., et al. PF1022A and related cyclodepsipeptides - a novel class of anthelmintics. Curr. Top. Med. Chem. 2002, 2:759-777.
    • (2002) Curr. Top. Med. Chem. , vol.2 , pp. 759-777
    • Scherkenbeck, J.1
  • 22
    • 84865190802 scopus 로고
    • Fujisawa Pharmaceutical Co., Ltd.
    • Japan. Preparation of depsipeptides derivatives as anthelmintics. PCT Int. Appl., WO 9319053 A1 19930930; ref. CAN 121:134806
    • Nishiyama, H. et al. (1993) Fujisawa Pharmaceutical Co., Ltd., Japan. Preparation of depsipeptides derivatives as anthelmintics. PCT Int. Appl., 118 pp. WO 9319053 A1 19930930; ref. CAN 121:134806.
    • (1993) , pp. 118
    • Nishiyama, H.1
  • 23
    • 60349090957 scopus 로고    scopus 로고
    • In vitro synthesis of new cyclodepsipeptides of the PF1022-type: probing the α-D-hydroxy acid tolerance of PH1022 synthetase
    • Müller J., et al. In vitro synthesis of new cyclodepsipeptides of the PF1022-type: probing the α-D-hydroxy acid tolerance of PH1022 synthetase. Chembiochem 2009, 10:323-328.
    • (2009) Chembiochem , vol.10 , pp. 323-328
    • Müller, J.1
  • 24
    • 0034625433 scopus 로고    scopus 로고
    • Biosynthesis of PF1022A and related cyclooctadepsipeptides
    • Weckwerth W., et al. Biosynthesis of PF1022A and related cyclooctadepsipeptides. J. Biol. Chem. 2000, 275:17909-17915.
    • (2000) J. Biol. Chem. , vol.275 , pp. 17909-17915
    • Weckwerth, W.1
  • 25
    • 0028284699 scopus 로고
    • The peptide synthetase catalyzing cyclosporine production in Tolypocladium niveum is encoded by a giant 45.8-kilobase open reading frame
    • Weber G., et al. The peptide synthetase catalyzing cyclosporine production in Tolypocladium niveum is encoded by a giant 45.8-kilobase open reading frame. Curr. Genet. 1994, 26:120-125.
    • (1994) Curr. Genet. , vol.26 , pp. 120-125
    • Weber, G.1
  • 26
    • 3042742578 scopus 로고    scopus 로고
    • Para-position derivatives of fungal anthelmintic cyclodepsipeptides engineered with Streptomyces venezuelae antibiotic biosynthetic genes
    • Yanai K., et al. Para-position derivatives of fungal anthelmintic cyclodepsipeptides engineered with Streptomyces venezuelae antibiotic biosynthetic genes. Nat. Biotechnol. 2004, 22:848-855.
    • (2004) Nat. Biotechnol. , vol.22 , pp. 848-855
    • Yanai, K.1
  • 27
    • 0000789375 scopus 로고
    • Neuropharmacological mechanism of action of PF1022A, an antinematode anthelmintic with a new structure of cyclic depsipeptide, on Angiostrongylus cantonensis and isolated frog rectus
    • Terada M. Neuropharmacological mechanism of action of PF1022A, an antinematode anthelmintic with a new structure of cyclic depsipeptide, on Angiostrongylus cantonensis and isolated frog rectus. Jpn. J. Parasitol. 1992, 41:108-117.
    • (1992) Jpn. J. Parasitol. , vol.41 , pp. 108-117
    • Terada, M.1
  • 28
    • 0031689882 scopus 로고    scopus 로고
    • Effects of amorphous and polymorphs of PF1022A, a new antinematode drug, on Angiostrongylus costaricensis in mice
    • Kachi S., et al. Effects of amorphous and polymorphs of PF1022A, a new antinematode drug, on Angiostrongylus costaricensis in mice. Jpn. J. Parasitol. 1998, 77:235-245.
    • (1998) Jpn. J. Parasitol. , vol.77 , pp. 235-245
    • Kachi, S.1
  • 29
    • 0030466249 scopus 로고    scopus 로고
    • Anthelmintic actions of the cyclic depsipeptide PF1022A and its electrophysiological effects on muscle cells of Ascaris suum
    • Martin R.J., et al. Anthelmintic actions of the cyclic depsipeptide PF1022A and its electrophysiological effects on muscle cells of Ascaris suum. Pestic. Sci. 1996, 48:343-349.
    • (1996) Pestic. Sci. , vol.48 , pp. 343-349
    • Martin, R.J.1
  • 30
    • 0000953375 scopus 로고
    • Effects of PF1022A on developing larvae of Angiostrongylus costaricensis in mice, with special reference to route, dose and formulation
    • Terada M., et al. Effects of PF1022A on developing larvae of Angiostrongylus costaricensis in mice, with special reference to route, dose and formulation. Jpn. J. Parasitol. 1993, 42:199-210.
    • (1993) Jpn. J. Parasitol. , vol.42 , pp. 199-210
    • Terada, M.1
  • 31
    • 0001137848 scopus 로고
    • Effects of PF1022A, a newly developed gabergic anthelmintic, on adult stage of Angiostrongylus cantonensis in rats
    • Akyol C.V., et al. Effects of PF1022A, a newly developed gabergic anthelmintic, on adult stage of Angiostrongylus cantonensis in rats. Jpn. J. Parasitol. 1993, 42:220-226.
    • (1993) Jpn. J. Parasitol. , vol.42 , pp. 220-226
    • Akyol, C.V.1
  • 32
    • 0001339149 scopus 로고
    • Effects of PF1022A on Angiostrongylus cantonensis staying in the central nervous system of rats and mice
    • Kachi S., et al. Effects of PF1022A on Angiostrongylus cantonensis staying in the central nervous system of rats and mice. Jpn. J. Parasitol. 1994, 43:483-488.
    • (1994) Jpn. J. Parasitol. , vol.43 , pp. 483-488
    • Kachi, S.1
  • 33
    • 0028811598 scopus 로고
    • Effects of PF1022A on adult Angiostrongylus cantonensis in the pulmonary arteries and larvae migration into the central nervous system of rats
    • Kachi S., et al. Effects of PF1022A on adult Angiostrongylus cantonensis in the pulmonary arteries and larvae migration into the central nervous system of rats. Parasitol. Res. 1995, 81:631-637.
    • (1995) Parasitol. Res. , vol.81 , pp. 631-637
    • Kachi, S.1
  • 34
    • 0032076726 scopus 로고    scopus 로고
    • Effects of anthelmintics with different modes of action on the behavior and development of Caenorhabditis elegans
    • Bernt U., et al. Effects of anthelmintics with different modes of action on the behavior and development of Caenorhabditis elegans. Fundam. Appl. Nematol. 1998, 21:251-263.
    • (1998) Fundam. Appl. Nematol. , vol.21 , pp. 251-263
    • Bernt, U.1
  • 35
    • 0034788818 scopus 로고    scopus 로고
    • Activity of the cyclic depsipeptide emodepside (BAY 44-4400) against larval and adult stages of nematodes in rodents and the influence on worm survival
    • Harder A., von Samson-Himmelstjerna G. Activity of the cyclic depsipeptide emodepside (BAY 44-4400) against larval and adult stages of nematodes in rodents and the influence on worm survival. Parasitol. Res. 2001, 87:924-928.
    • (2001) Parasitol. Res. , vol.87 , pp. 924-928
    • Harder, A.1    von Samson-Himmelstjerna, G.2
  • 36
    • 0033647085 scopus 로고    scopus 로고
    • Synergistic action of BAY 44-4400 and piperazine on nematodes of the mouse in-vitro and in-vivo: a light and transmission electron microscopic study
    • Nicolay F., et al. Synergistic action of BAY 44-4400 and piperazine on nematodes of the mouse in-vitro and in-vivo: a light and transmission electron microscopic study. Parasitol. Res. 2000, 86:982-992.
    • (2000) Parasitol. Res. , vol.86 , pp. 982-992
    • Nicolay, F.1
  • 37
    • 34547397989 scopus 로고    scopus 로고
    • Efficacy of a combination of emodepside plus praziquantel against larval and adult stages of nematodes (Trichuris muris, Angiostrongylus cantonensis) in rodents
    • Schmahl G., et al. Efficacy of a combination of emodepside plus praziquantel against larval and adult stages of nematodes (Trichuris muris, Angiostrongylus cantonensis) in rodents. Parasitol. Res. 2007, 101:S77-S84.
    • (2007) Parasitol. Res. , vol.101
    • Schmahl, G.1
  • 38
    • 0029089287 scopus 로고
    • Anthelmintic profile of the cyclodepsipeptide PF1022A in in-vitro and in-vivo models
    • Conder G.A., et al. Anthelmintic profile of the cyclodepsipeptide PF1022A in in-vitro and in-vivo models. J. Antibiot. 1995, 48:820-823.
    • (1995) J. Antibiot. , vol.48 , pp. 820-823
    • Conder, G.A.1
  • 39
    • 26844562026 scopus 로고    scopus 로고
    • Effects of a combination of emodepside and praziquantel on parasites of reptiles and rodents
    • Mehlhorn H., et al. Effects of a combination of emodepside and praziquantel on parasites of reptiles and rodents. Parasitol. Res. 2005, 97(Suppl. 1):S65-S69.
    • (2005) Parasitol. Res. , vol.97 , Issue.SUPPL. 1
    • Mehlhorn, H.1
  • 40
    • 26844431981 scopus 로고    scopus 로고
    • Efficacy of a topically administered combination of emodepside and praziquantel against mature and immature Ancylostoma tubaeforme in domestic cats
    • Altreuther G., et al. Efficacy of a topically administered combination of emodepside and praziquantel against mature and immature Ancylostoma tubaeforme in domestic cats. Parasitol. Res. 2005, 97(Suppl. 1):S51-S57.
    • (2005) Parasitol. Res. , vol.97 , Issue.SUPPL. 1
    • Altreuther, G.1
  • 41
    • 26844472830 scopus 로고    scopus 로고
    • Field evaluation of the efficacy and safety of emodepside/praziquantel spot-on solution against naturally acquired nematode and cestode infections in domestic cats
    • Altreuther G., et al. Field evaluation of the efficacy and safety of emodepside/praziquantel spot-on solution against naturally acquired nematode and cestode infections in domestic cats. Parasitol. Res. 2005, 97(Suppl. 1):S58-S64.
    • (2005) Parasitol. Res. , vol.97 , Issue.SUPPL. 1
    • Altreuther, G.1
  • 42
    • 80052382495 scopus 로고    scopus 로고
    • ® oral suspension for dogs) against naturally acquired nematode and Isospora spp. infections in dogs
    • ® oral suspension for dogs) against naturally acquired nematode and Isospora spp. infections in dogs. Parasitol. Res. 2011, 109(Suppl. 1):S21-S28.
    • (2011) Parasitol. Res. , vol.109 , Issue.SUPPL. 1
    • Altreuther, G.1
  • 43
    • 80052373524 scopus 로고    scopus 로고
    • ® oral suspension for dogs) against prepatent and patent infection with Isospora canis and Isospora ohioensis-complex in dogs
    • ® oral suspension for dogs) against prepatent and patent infection with Isospora canis and Isospora ohioensis-complex in dogs. Parasitol. Res. 2011, 109(Suppl. 1):S9-S20.
    • (2011) Parasitol. Res. , vol.109 , Issue.SUPPL. 1
    • Altreuther, G.1
  • 44
    • 0000048061 scopus 로고
    • Anthelmintic effects of PF1022, a new cyclic depsipeptide, on the intestinal nematodes in dogs and cats
    • Proceedings of the 110th Meeting of the Japanese Soc. Vet. Science
    • Fukashe, T. et al. (1990) Anthelmintic effects of PF1022, a new cyclic depsipeptide, on the intestinal nematodes in dogs and cats. Proceedings of the 110th Meeting of the Japanese Soc. Vet. Science, p. 122.
    • (1990) , pp. 122
    • Fukashe, T.1
  • 45
    • 26844554115 scopus 로고    scopus 로고
    • Evaluation of the efficacy of emodepside plus praziquantel topical solution against ascarid infections (Toxocara cati or Toxascaris leonina) in cats
    • Reinemeyer C.R., et al. Evaluation of the efficacy of emodepside plus praziquantel topical solution against ascarid infections (Toxocara cati or Toxascaris leonina) in cats. Parasitol. Res. 2005, 97(Suppl. 1):S41-S50.
    • (2005) Parasitol. Res. , vol.97 , Issue.SUPPL. 1
    • Reinemeyer, C.R.1
  • 46
    • 80052350973 scopus 로고    scopus 로고
    • ® oral suspension for dogs (0.1% emodepside and 2% toltrazuril) against experimental nematode (Toxocara cati and Ancylostoma tubaeforme) infections in cats
    • ® oral suspension for dogs (0.1% emodepside and 2% toltrazuril) against experimental nematode (Toxocara cati and Ancylostoma tubaeforme) infections in cats. Parasitol. Res. 2011, 109(Suppl. 1):S37-S43.
    • (2011) Parasitol. Res. , vol.109 , Issue.SUPPL. 1
    • Petry, G.1
  • 47
    • 80052373774 scopus 로고    scopus 로고
    • ® oral suspension for dogs) against mixed experimental Isospora felis/Isospora rivolta infection in cats
    • ® oral suspension for dogs) against mixed experimental Isospora felis/Isospora rivolta infection in cats. Parasitol. Res. 2011, 109(Suppl. 1):S29-S36.
    • (2011) Parasitol. Res. , vol.109 , Issue.SUPPL. 1
    • Petry, G.1
  • 48
    • 34547403123 scopus 로고    scopus 로고
    • Efficacy of emodepside plus praziquantel topical solution against immature stages of nematodes (Ancylostoma sp. and Toxocara sp.) in cats
    • Schaper R., et al. Efficacy of emodepside plus praziquantel topical solution against immature stages of nematodes (Ancylostoma sp. and Toxocara sp.) in cats. Parasitol. Res. 2007, 101:S63-S68.
    • (2007) Parasitol. Res. , vol.101
    • Schaper, R.1
  • 49
    • 80052360368 scopus 로고    scopus 로고
    • ® oral suspension for dogs) against Toxocara canis, Uncinaria stenocephala and Ancylostoma caninum in dogs
    • ® oral suspension for dogs) against Toxocara canis, Uncinaria stenocephala and Ancylostoma caninum in dogs. Parasitol. Res. 2011, 109(Suppl. 1):S1-S8.
    • (2011) Parasitol. Res. , vol.109 , Issue.SUPPL. 1
    • Schimmel, A.1
  • 50
    • 0033813307 scopus 로고    scopus 로고
    • In vivo activities of the new anthelmintic depsipeptide PF1022A
    • von Samson-Himmelstjerna G., et al. In vivo activities of the new anthelmintic depsipeptide PF1022A. Parasitol. Res. 2000, 86:194-199.
    • (2000) Parasitol. Res. , vol.86 , pp. 194-199
    • von Samson-Himmelstjerna, G.1
  • 51
    • 15944380075 scopus 로고    scopus 로고
    • Efficacy of two cyclooctadepsipeptides, PF1022A and emodepside, against anthelmintic-resistant nematodes in sheep and cattle
    • von Samson-Himmelstjerna G., et al. Efficacy of two cyclooctadepsipeptides, PF1022A and emodepside, against anthelmintic-resistant nematodes in sheep and cattle. Parasitology 2005, 130:343-347.
    • (2005) Parasitology , vol.130 , pp. 343-347
    • von Samson-Himmelstjerna, G.1
  • 52
    • 0035452083 scopus 로고    scopus 로고
    • Effects of Bay 44-4400, a new cyclodepsipeptide, on developing stages of filariae (Acanthocheilonema viteae, Brugia malayi, Litomosoides sigmodontis) in the rodent Mastomys coucha
    • Zahner H., et al. Effects of Bay 44-4400, a new cyclodepsipeptide, on developing stages of filariae (Acanthocheilonema viteae, Brugia malayi, Litomosoides sigmodontis) in the rodent Mastomys coucha. Acta Trop. 2001, 80:19-28.
    • (2001) Acta Trop. , vol.80 , pp. 19-28
    • Zahner, H.1
  • 53
    • 0034790061 scopus 로고    scopus 로고
    • Filaricidal efficacy of anthelmintically active cyclodepsipeptides
    • Zahner H., et al. Filaricidal efficacy of anthelmintically active cyclodepsipeptides. Int. J. Parasitol. 2001, 31:1515-1522.
    • (2001) Int. J. Parasitol. , vol.31 , pp. 1515-1522
    • Zahner, H.1
  • 54
    • 0030468527 scopus 로고    scopus 로고
    • Ionophorous and anthelmintic activity of PF1022A, a cyclooctadepsipeptide, are not related
    • Gessner G., et al. Ionophorous and anthelmintic activity of PF1022A, a cyclooctadepsipeptide, are not related. Pestic. Sci. 1996, 48:399-407.
    • (1996) Pestic. Sci. , vol.48 , pp. 399-407
    • Gessner, G.1
  • 55
    • 0037282198 scopus 로고    scopus 로고
    • The effect of the anthelmintic emodepside at the neuromuscular junction of the parasitic nematode Ascaris suum
    • Willson J., et al. The effect of the anthelmintic emodepside at the neuromuscular junction of the parasitic nematode Ascaris suum. Parasitology 2003, 126:79-86.
    • (2003) Parasitology , vol.126 , pp. 79-86
    • Willson, J.1
  • 56
    • 84865166404 scopus 로고    scopus 로고
    • A possible mechanism for the action of the novel anthelmintic emodepside, using Ascaris suum body wall muscle preparations
    • Willson J., et al. A possible mechanism for the action of the novel anthelmintic emodepside, using Ascaris suum body wall muscle preparations. J. Physiol. 2001, 536:132-133.
    • (2001) J. Physiol. , vol.536 , pp. 132-133
    • Willson, J.1
  • 57
    • 0030045460 scopus 로고    scopus 로고
    • Characterization of subtypes of γ-aminobutyric acid receptors in an Ascaris muscle preparation by binding assay and binding of PF1022A, a new anthelmintic, on the receptors
    • Chen W., et al. Characterization of subtypes of γ-aminobutyric acid receptors in an Ascaris muscle preparation by binding assay and binding of PF1022A, a new anthelmintic, on the receptors. Parasitol. Res. 1996, 82:97-101.
    • (1996) Parasitol. Res. , vol.82 , pp. 97-101
    • Chen, W.1
  • 58
    • 84987138245 scopus 로고
    • Studies involving avermectin and the 4-aminobutyric acid (GABA) receptor of Ascaris suum muscle
    • Holden-Dye L., et al. Studies involving avermectin and the 4-aminobutyric acid (GABA) receptor of Ascaris suum muscle. Pest Manag. Sci. 1988, 24:231-245.
    • (1988) Pest Manag. Sci. , vol.24 , pp. 231-245
    • Holden-Dye, L.1
  • 60
    • 0033361969 scopus 로고    scopus 로고
    • One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction
    • Richmond J.E., Jorgensen E.M. One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction. Nat. Neurosci. 1999, 2:791-797.
    • (1999) Nat. Neurosci. , vol.2 , pp. 791-797
    • Richmond, J.E.1    Jorgensen, E.M.2
  • 61
    • 0033169088 scopus 로고    scopus 로고
    • The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor
    • Bamber B.A., et al. The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor. J. Neurosci. 1999, 19:5348-5359.
    • (1999) J. Neurosci. , vol.19 , pp. 5348-5359
    • Bamber, B.A.1
  • 62
    • 14844334970 scopus 로고    scopus 로고
    • The composition of the GABA receptor at the Caenorhabditis elegans neuromuscular junction
    • Bamber B.A., et al. The composition of the GABA receptor at the Caenorhabditis elegans neuromuscular junction. Br. J. Pharmacol. 2005, 144:502-509.
    • (2005) Br. J. Pharmacol. , vol.144 , pp. 502-509
    • Bamber, B.A.1
  • 63
    • 84863815883 scopus 로고    scopus 로고
    • Decreased emodepside sensitivity in unc-49 γ-aminobutyric acid (GABA)-receptor-deficient Caenorhabditis elegans
    • Miltsch S.M., et al. Decreased emodepside sensitivity in unc-49 γ-aminobutyric acid (GABA)-receptor-deficient Caenorhabditis elegans. Int. J. Parasitol. 2012, 42:761-770.
    • (2012) Int. J. Parasitol. , vol.42 , pp. 761-770
    • Miltsch, S.M.1
  • 64
    • 0035348158 scopus 로고    scopus 로고
    • Latrophilin-like receptor from the parasitic nematode Haemonchus contortus as target for the anthelmintic depsipeptide PF1022A
    • Saeger B., et al. Latrophilin-like receptor from the parasitic nematode Haemonchus contortus as target for the anthelmintic depsipeptide PF1022A. FASEB J. 2001, 15:1332-1334.
    • (2001) FASEB J. , vol.15 , pp. 1332-1334
    • Saeger, B.1
  • 65
    • 84858027355 scopus 로고    scopus 로고
    • FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development
    • O'Sullivan M.L., et al. FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development. Neuron 2012, 73:903-910.
    • (2012) Neuron , vol.73 , pp. 903-910
    • O'Sullivan, M.L.1
  • 66
    • 79961071808 scopus 로고    scopus 로고
    • Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities
    • Silva J.P., et al. Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:12113-12118.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 12113-12118
    • Silva, J.P.1
  • 67
    • 84858597379 scopus 로고    scopus 로고
    • High affinity neurexin binding to cell adhesion G-protein-coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex
    • Boucard A.A., et al. High affinity neurexin binding to cell adhesion G-protein-coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex. J. Biol. Chem. 2012, 287:9399-9413.
    • (2012) J. Biol. Chem. , vol.287 , pp. 9399-9413
    • Boucard, A.A.1
  • 68
    • 68249141238 scopus 로고    scopus 로고
    • The putative cyclooctadepsipeptide receptor depsiphilin of the canine hookworm Ancylostoma caninum
    • Krüger N., et al. The putative cyclooctadepsipeptide receptor depsiphilin of the canine hookworm Ancylostoma caninum. Parasitol. Res. 2009, 105(Suppl 1):91-100.
    • (2009) Parasitol. Res. , vol.105 , Issue.SUPPL. 1 , pp. 91-100
    • Krüger, N.1
  • 69
    • 26844574375 scopus 로고    scopus 로고
    • Putative G protein-coupled receptors in parasitic nematodes - potential targets for the new anthelmintic class cyclooctadepsipeptides?
    • Welz C., et al. Putative G protein-coupled receptors in parasitic nematodes - potential targets for the new anthelmintic class cyclooctadepsipeptides?. Parasitol. Res. 2005, 97(Suppl. 1):S22-S32.
    • (2005) Parasitol. Res. , vol.97 , Issue.SUPPL. 1
    • Welz, C.1
  • 70
    • 1542314825 scopus 로고    scopus 로고
    • Latrophilin is required for toxicity of black widow spider venom in Caenorhabditis elegans
    • Mee C.J., et al. Latrophilin is required for toxicity of black widow spider venom in Caenorhabditis elegans. Biochem. J. 2004, 378:185-191.
    • (2004) Biochem. J. , vol.378 , pp. 185-191
    • Mee, C.J.1
  • 71
    • 35148867124 scopus 로고    scopus 로고
    • The calcium-activated potassium channel, SLO-1, is required for the action of the novel cyclo-octadepsipeptide anthelmintic, emodepside, in Caenorhabditis elegans
    • Guest M., et al. The calcium-activated potassium channel, SLO-1, is required for the action of the novel cyclo-octadepsipeptide anthelmintic, emodepside, in Caenorhabditis elegans. Int. J. Parasitol. 2007, 37:1577-1588.
    • (2007) Int. J. Parasitol. , vol.37 , pp. 1577-1588
    • Guest, M.1
  • 72
    • 4143086112 scopus 로고    scopus 로고
    • Latrotoxin receptor signaling engages the UNC-13-dependent vesicle-priming pathway in C. elegans
    • Willson J., et al. Latrotoxin receptor signaling engages the UNC-13-dependent vesicle-priming pathway in C. elegans. Curr. Biol. 2004, 14:1374-1379.
    • (2004) Curr. Biol. , vol.14 , pp. 1374-1379
    • Willson, J.1
  • 73
    • 33746315609 scopus 로고    scopus 로고
    • The FLP-side of nematodes
    • McVeigh P., et al. The FLP-side of nematodes. Trends Parasitol. 2006, 22:385-396.
    • (2006) Trends Parasitol. , vol.22 , pp. 385-396
    • McVeigh, P.1
  • 74
    • 59849122946 scopus 로고    scopus 로고
    • FMRFamide-like neuropeptides as putative ligands of the latrophilin-like HC110-R from Haemonchus contortus
    • Mühlfeld S., et al. FMRFamide-like neuropeptides as putative ligands of the latrophilin-like HC110-R from Haemonchus contortus. Mol. Biochem. Parasitol. 2009, 164:162-164.
    • (2009) Mol. Biochem. Parasitol. , vol.164 , pp. 162-164
    • Mühlfeld, S.1
  • 75
    • 33947379230 scopus 로고    scopus 로고
    • Effects of the novel anthelmintic emodepside on the locomotion, egg-laying behaviour and development of Caenorhabditis elegans
    • Bull K., et al. Effects of the novel anthelmintic emodepside on the locomotion, egg-laying behaviour and development of Caenorhabditis elegans. Int. J. Parasitol. 2007, 37:627-636.
    • (2007) Int. J. Parasitol. , vol.37 , pp. 627-636
    • Bull, K.1
  • 76
    • 84861694065 scopus 로고    scopus 로고
    • Molecular and genetic determinants of the inhibitory action of emodepside on C. elegans muscle
    • Division of Cell Sciences 2005, University of Southampton PhD Thesis: Southampton
    • Amliwala, K. (2005) Molecular and genetic determinants of the inhibitory action of emodepside on C. elegans muscle, Division of Cell Sciences 2005, University of Southampton PhD Thesis: Southampton.
    • (2005)
    • Amliwala, K.1
  • 77
    • 79955750096 scopus 로고    scopus 로고
    • SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants
    • Welz C., et al. SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants. PLoS Pathog. 2011, 7:e1001330.
    • (2011) PLoS Pathog. , vol.7
    • Welz, C.1
  • 78
    • 79956336717 scopus 로고    scopus 로고
    • Selective toxicity of the anthelmintic emodepside revealed by heterologous expression of human KCNMA1 in Caenorhabditis elegans
    • Crisford A., et al. Selective toxicity of the anthelmintic emodepside revealed by heterologous expression of human KCNMA1 in Caenorhabditis elegans. Mol. Pharmacol. 2011, 79:1031-1043.
    • (2011) Mol. Pharmacol. , vol.79 , pp. 1031-1043
    • Crisford, A.1
  • 79
    • 80052250730 scopus 로고    scopus 로고
    • On the mode of action of emodepside: slow effects on membrane potential and voltage-activated currents in Ascaris suum
    • Buxton S.K., et al. On the mode of action of emodepside: slow effects on membrane potential and voltage-activated currents in Ascaris suum. Br. J. Pharmacol. 2011, 164:453-470.
    • (2011) Br. J. Pharmacol. , vol.164 , pp. 453-470
    • Buxton, S.K.1
  • 80
    • 0142243144 scopus 로고    scopus 로고
    • Conditional protein phosphorylation regulates BK channel activity in rat cerebellar Purkinje neurons
    • Widmer H.A., et al. Conditional protein phosphorylation regulates BK channel activity in rat cerebellar Purkinje neurons. J. Physiol. 2003, 552:379-391.
    • (2003) J. Physiol. , vol.552 , pp. 379-391
    • Widmer, H.A.1
  • 81
    • 33646825244 scopus 로고    scopus 로고
    • 2+ channels via latrophilin in beta-cells
    • 2+ channels via latrophilin in beta-cells. J. Biol. Chem. 2006, 281:5522-5531.
    • (2006) J. Biol. Chem. , vol.281 , pp. 5522-5531
    • Lajus, S.1
  • 82
    • 84861691324 scopus 로고    scopus 로고
    • Worms take to the slo lane: a perspective on the mode of action of emodepside
    • Holden-Dye L., et al. Worms take to the slo lane: a perspective on the mode of action of emodepside. Invert. Neurosci. 2012, 12:29-36.
    • (2012) Invert. Neurosci. , vol.12 , pp. 29-36
    • Holden-Dye, L.1
  • 83
    • 36448951543 scopus 로고    scopus 로고
    • SLO, SLO, quick, quick, slow: calcium-activated potassium channels as regulators of Caenorhabditis elegans behaviour and targets for anthelmintics
    • Holden-Dye L., et al. SLO, SLO, quick, quick, slow: calcium-activated potassium channels as regulators of Caenorhabditis elegans behaviour and targets for anthelmintics. Invert. Neurosci. 2007, 7:199-208.
    • (2007) Invert. Neurosci. , vol.7 , pp. 199-208
    • Holden-Dye, L.1
  • 84
    • 4444290353 scopus 로고    scopus 로고
    • Veterinary anthelmintics: old and new
    • McKellar Q.A., Jackson F. Veterinary anthelmintics: old and new. Trends Parasitol. 2004, 20:456-461.
    • (2004) Trends Parasitol. , vol.20 , pp. 456-461
    • McKellar, Q.A.1    Jackson, F.2
  • 85
    • 0024273591 scopus 로고
    • The role of the cytoskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazoles
    • Lacey E. The role of the cytoskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazoles. Int. J. Parasitol. 1988, 18:885-936.
    • (1988) Int. J. Parasitol. , vol.18 , pp. 885-936
    • Lacey, E.1
  • 86
    • 0030767507 scopus 로고    scopus 로고
    • Modes of action of anthelmintic drugs
    • Martin R.J. Modes of action of anthelmintic drugs. Vet. J. 1997, 154:11-34.
    • (1997) Vet. J. , vol.154 , pp. 11-34
    • Martin, R.J.1
  • 87
    • 0033549902 scopus 로고    scopus 로고
    • Soluble guanylyl cyclases in Caenorhabditis elegans: NO is not the answer
    • Morton D.B., et al. Soluble guanylyl cyclases in Caenorhabditis elegans: NO is not the answer. Curr. Biol. 1999, 9:R546-R547.
    • (1999) Curr. Biol. , vol.9
    • Morton, D.B.1
  • 88
    • 0028033957 scopus 로고
    • Synthesis of PF1022A, an anthelmintic cyclodepsipeptide
    • Dutton F.E., Nelson S.J. Synthesis of PF1022A, an anthelmintic cyclodepsipeptide. J. Antibiot. (Tokyo) 1994, 47:1322-1327.
    • (1994) J. Antibiot. (Tokyo) , vol.47 , pp. 1322-1327
    • Dutton, F.E.1    Nelson, S.J.2
  • 89
    • 0002280019 scopus 로고
    • Synthesis and anthelmintic activity of the cyclodepsipeptide, PF1022A
    • Kobayashi M., et al. Synthesis and anthelmintic activity of the cyclodepsipeptide, PF1022A. Sankyo Kenkyusho Nenpo 1994, 46:67-75.
    • (1994) Sankyo Kenkyusho Nenpo , vol.46 , pp. 67-75
    • Kobayashi, M.1
  • 90
    • 0031016106 scopus 로고    scopus 로고
    • Solid-phase synthesis of cyclooctadepsipeptide PF1022A analogs using a cyclization-cleavage method with oxime resin
    • Lee B.H. Solid-phase synthesis of cyclooctadepsipeptide PF1022A analogs using a cyclization-cleavage method with oxime resin. Tetrahedron Lett. 1997, 38:757-760.
    • (1997) Tetrahedron Lett. , vol.38 , pp. 757-760
    • Lee, B.H.1
  • 91
    • 85007991332 scopus 로고
    • Total synthesis of the anthelmintic cyclodepsipeptide PF1022A
    • Ohyama M., et al. Total synthesis of the anthelmintic cyclodepsipeptide PF1022A. Biosci. Biotechnol. Biochem. 1994, 58:1193-1194.
    • (1994) Biosci. Biotechnol. Biochem. , vol.58 , pp. 1193-1194
    • Ohyama, M.1
  • 92
    • 0029079727 scopus 로고
    • A highly efficient synthesis of the anthelmintic cyclooctadepsipeptide PF1022A
    • Scherkenbeck J., et al. A highly efficient synthesis of the anthelmintic cyclooctadepsipeptide PF1022A. Tetrahedron 1995, 51:8459-8470.
    • (1995) Tetrahedron , vol.51 , pp. 8459-8470
    • Scherkenbeck, J.1
  • 93
    • 77950243797 scopus 로고    scopus 로고
    • Chemistry of anthelmintic cyclodepsipeptides
    • Ohyama M., et al. Chemistry of anthelmintic cyclodepsipeptides. Sci. Rep. Meiji Seika Kaisha 2006, 45:8-31.
    • (2006) Sci. Rep. Meiji Seika Kaisha , vol.45 , pp. 8-31
    • Ohyama, M.1
  • 94
    • 17544395284 scopus 로고    scopus 로고
    • PF1022A - a novel anthelmintic cyclooctadepsipeptide. Modification and exchange of the N-methyl leucine residues
    • Scherkenbeck J., et al. PF1022A - a novel anthelmintic cyclooctadepsipeptide. Modification and exchange of the N-methyl leucine residues. Bioorg. Med. Chem. Lett. 1998, 8:1035-1040.
    • (1998) Bioorg. Med. Chem. Lett. , vol.8 , pp. 1035-1040
    • Scherkenbeck, J.1
  • 95
    • 0034763130 scopus 로고    scopus 로고
    • Synthesis and anthelmintic activity of thioamide analogues of cyclic octadepsipeptides such as PF1022A
    • Jeschke P., et al. Synthesis and anthelmintic activity of thioamide analogues of cyclic octadepsipeptides such as PF1022A. Pest Manag. Sci. 2001, 57:1000-1006.
    • (2001) Pest Manag. Sci. , vol.57 , pp. 1000-1006
    • Jeschke, P.1
  • 96
    • 18744394963 scopus 로고    scopus 로고
    • Synthesis of anthelmintically active N-methylated amidoxime analogues of the cyclic octadepsipeptide PF1022A
    • Jeschke P., et al. Synthesis of anthelmintically active N-methylated amidoxime analogues of the cyclic octadepsipeptide PF1022A. Pest Manag. Sci. 2002, 58:1205-1215.
    • (2002) Pest Manag. Sci. , vol.58 , pp. 1205-1215
    • Jeschke, P.1
  • 97
    • 84865156069 scopus 로고    scopus 로고
    • Bayer AG. Desoxycyclodepsipeptides and their use for combating endoparasites, WO 98/55469 A1
    • Dyker, H. et al. (1998) Bayer AG. Desoxycyclodepsipeptides and their use for combating endoparasites, WO 98/55469 A1.
    • (1998)
    • Dyker, H.1
  • 98
    • 0035356075 scopus 로고    scopus 로고
    • Azadepsipeptides: synthesis and evaluation of a novel class of peptidomimetics
    • Dyker H., et al. Azadepsipeptides: synthesis and evaluation of a novel class of peptidomimetics. J. Org. Chem. 2001, 66:3760-3766.
    • (2001) J. Org. Chem. , vol.66 , pp. 3760-3766
    • Dyker, H.1
  • 99
    • 0033014855 scopus 로고    scopus 로고
    • Synthesis, conformational studies and anthelmintic activity of constrained PF1022A analogue
    • Scherkenbeck J., et al. Synthesis, conformational studies and anthelmintic activity of constrained PF1022A analogue. Pestic. Sci. 1999, 55:457-461.
    • (1999) Pestic. Sci. , vol.55 , pp. 457-461
    • Scherkenbeck, J.1
  • 100
    • 0032560774 scopus 로고    scopus 로고
    • Epsilon-lactam analogs of the anthelmintic cyclodepsipeptide PF1022A
    • Dutton F.E., Lee B.H. Epsilon-lactam analogs of the anthelmintic cyclodepsipeptide PF1022A. Tetrahedron Lett. 1998, 39:5313-5316.
    • (1998) Tetrahedron Lett. , vol.39 , pp. 5313-5316
    • Dutton, F.E.1    Lee, B.H.2
  • 101
    • 8844260502 scopus 로고    scopus 로고
    • Chimeric cyclodepsipeptides as mimetics for the anthelmintic PF1022A
    • Dyker H., et al. Chimeric cyclodepsipeptides as mimetics for the anthelmintic PF1022A. Bioorg. Med. Chem. Lett. 2004, 14:6129-6132.
    • (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 6129-6132
    • Dyker, H.1
  • 102
    • 26844507116 scopus 로고    scopus 로고
    • Influence of the cyclooctadepsipeptides PF1022A and PF1022E as natural products on the design of semi-synthetic anthelmintics such as emodepside
    • Jeschke R., et al. Influence of the cyclooctadepsipeptides PF1022A and PF1022E as natural products on the design of semi-synthetic anthelmintics such as emodepside. Parasitol. Res. 2005, 97(Suppl. 1):S11-S16.
    • (2005) Parasitol. Res. , vol.97 , Issue.SUPPL. 1
    • Jeschke, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.