Characterization of the Ca2+-Gated and Voltage-Dependent K+-Channel Slo-1 of Nematodes and Its Interaction with Emodepside

PLoS Neglected Tropical Diseases

Volumn 8, Issue 12, 2014, Pages

  Kulke, Daniel ^a,b   von Samson Himmelstjerna, Georg ^a   Miltsch, Sandra M ^a   Wolstenholme, Adrian J ^c   Jex, Aaron R ^d   Gasser, Robin B ^d   Ballesteros, Cristina ^e   Geary, Timothy G ^e   Keiser, Jennifer ^f   Townson, Simon ^g   Harder, Achim ^h   Krücken, Jürgen ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b BAYER PHARMA AG   (Germany)

^c UNIVERSITY OF GEORGIA   (United States)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e MCGILL UNIVERSITY   (Canada)

^f SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^g NORTHWICK PARK INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^h HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; EMODEPSIDE; TRANSCRIPTOME; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL; ANTHELMINTIC AGENT; CAENORHABDITIS ELEGANS PROTEIN; CALCIUM; DEPSIPEPTIDE; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; SLO-1 PROTEIN, C ELEGANS;

ADULT; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FEMALE; GENE; GENE AMPLIFICATION; GENE SEQUENCE; MALE; MEMBRANE POTENTIAL; MICROINJECTION; NEMATODE; NONHUMAN; OOCYTE; PHYLOGENETIC TREE; PHYLOGENY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SLO 1 GENE; VOLTAGE CLAMP TECHNIQUE; XENOPUS LAEVIS; ANIMAL; CAENORHABDITIS ELEGANS; DRUG EFFECTS; GENETICS; METABOLISM; PATCH CLAMP TECHNIQUE; PHYSIOLOGY;

ANIMALS; ANTHELMINTICS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CALCIUM; DEPSIPEPTIDES; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; PATCH-CLAMP TECHNIQUES; PHYLOGENY; XENOPUS LAEVIS;

EID: 84925436104     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0003401     Document Type: Article

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