The mitochondria-targeted imidazole substituted oleic acid ‘TPP-IOA’ affects mitochondrial bioenergetics and its protective efficacy in cells is influenced by cellular dependence on aerobic metabolism

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1858, Issue 1, 2017, Pages 73-85

  Maddalena, Lucas A ^a   Ghelfi, Mikel ^a   Atkinson, Jeffrey ^a   Stuart, Jeffrey A ^a  

^a BROCK UNIVERSITY   (Canada)

Author keywords

Apoptosis; Cytochrome c; Oxidative phosphorylation; Peroxidase; TPP IOA; Triphenylphosphonium

Indexed keywords

3 HYDROXYPROPYL TRIPHENYLPHOSPHONIUM CONJUGATED IMIDAZOLE SUBSTITUTED OLEIC ACID; ADENOSINE TRIPHOSPHATE; CYTOCHROME C; CYTOCHROME C PEROXIDASE; GALACTOSE; GLUCOSE; IMIDAZOLE; OLEIC ACID; OXIDOREDUCTASE INHIBITOR; RESORUFIN; UNCLASSIFIED DRUG; CARDIOLIPIN; IMIDAZOLE DERIVATIVE;

AEROBIC GLYCOLYSIS; AEROBIC METABOLISM; ANIMAL CELL; APOPTOSIS; ARTICLE; BIOENERGY; CELL RESPIRATION; CELL STRUCTURE; CONCENTRATION RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; FRAGMENTATION REACTION; HUMAN; HUMAN CELL; LIVER MITOCHONDRION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOLECULE; NONHUMAN; OXIDATION; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; REDUCTION; ANIMAL; CYTOSOL; DRUG EFFECTS; ENERGY METABOLISM; FEMALE; LONG EVANS RAT; METABOLISM; OXIDATION REDUCTION REACTION; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CARDIOLIPINS; CELL LINE, TUMOR; CELL RESPIRATION; CYTOCHROMES C; CYTOSOL; ENERGY METABOLISM; FEMALE; GALACTOSE; GLUCOSE; HUMANS; IMIDAZOLES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OLEIC ACID; OXIDATION-REDUCTION; OXIDATIVE PHOSPHORYLATION; RATS; RATS, LONG-EVANS;

EID: 84995485079     PISSN: 00052728     EISSN: 18792650     Source Type: Journal    
DOI: 10.1016/j.bbabio.2016.11.005     Document Type: Article

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