A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death

Nature Communications

Volumn 2, Issue 1, 2011, Pages

  Atkinson, Jeffrey ^a,b   Kapralov, Alexandr A ^a   Yanamala, Naveena ^a,c   Tyurina, Yulia Y ^a   Amoscato, Andrew A ^a   Pearce, Linda ^a   Peterson, Jim ^a   Huang, Zhentai ^a   Jiang, Jianfei ^a   Samhan Arias, Alejandro K ^a   Maeda, Akihiro ^a   Feng, Weihong ^a   Wasserloos, Karla ^a   Belikova, Natalia A ^a   Tyurin, Vladimir A ^a   Wang, Hong ^a,d   Fletcher, Jackie ^a,b   Wang, Yongsheng ^a,b   Vlasova, Irina I ^a   Klein Seetharaman, Judith ^c   Stoyanovsky, Detcho A ^a   Bayîr, Hülya ^a,c   Pitt, Bruce R ^a   Epperly, Michael W ^a,e   Greenberger, Joel S ^a,e   Kagan, Valerian E ^a   more..

^a UNIVERSITY OF PITTSBURGH   (United States)

^b BROCK UNIVERSITY   (Canada)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^e UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYPROPYL TRIPHENYLPHOSPHONIUM 12 (1H IMIDAZOL 1 YL)(Z) OCTADEC 9 ENOIC ACID; 3 HYDROXYPROPYL TRIPHENYLPHOSPHONIUM 12 (1H IMIDAZOL 1 YL)OCTADECANOIC ACID; 3 HYDROXYPROPYL TRIPHENYLPHOSPHONIUM METHYL 12 (IMIDAZOL 1 YL)(Z) OCTADEC 9 ENOATE; 3 HYDROXYPROPYL TRIPHENYLPHOSPHONIUM12 (IMIDAZOL 1 YL)DODECANOIC ACID; CARDIOLIPIN; CYTOCHROME C; IMIDAZOLE; OLEIC ACID; PEROXIDASE; STEARIC ACID; UNCLASSIFIED DRUG; CYTOCHROME C PEROXIDASE; ENZYME INHIBITOR; RADIOPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; FEMALE; MITOCHONDRION; MOUSE; NONHUMAN; RADIATION EXPOSURE; RADIATION PROTECTION; ANIMAL; C57BL MOUSE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ELECTRON SPIN RESONANCE; ENZYMOLOGY; MOLECULAR DYNAMICS;

MUS;

ANIMALS; CELL DEATH; CYTOCHROME-C PEROXIDASE; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYME INHIBITORS; FEMALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; RADIATION-PROTECTIVE AGENTS;

EID: 80055056709     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms1499     Document Type: Article

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