Human sirtuins: Structures and flexibility

Journal of Structural Biology

Volumn 196, Issue 3, 2016, Pages 534-542

  Sacconnay, Lionel ^a   Carrupt, Pierre Alain ^a   Nurisso, Alessandra ^a,b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Conformational changes; Modulators; Protein protein interactions; Sirtuins; Structure based drug design

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; ALANINE; LYSINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SIRTUIN; SIRTUIN 1; SIRTUIN 2; SIRTUIN 3; SIRTUIN 4; SIRTUIN 6; SIRTUIN 7;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; BETA SHEET; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTALLOGRAPHY; DIMERIZATION; ENZYME CONFORMATION; HUMAN; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; AGING; CHEMISTRY; NEOPLASM; ULTRASTRUCTURE; X RAY CRYSTALLOGRAPHY;

AGING; CRYSTALLOGRAPHY, X-RAY; HUMANS; NEOPLASMS; SIRTUINS;

EID: 84994052060     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2016.10.008     Document Type: Review

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