Lung surfactant metabolism: early in life, early in disease and target in cell therapy

Cell and Tissue Research

Volumn 367, Issue 3, 2017, Pages 721-735

  Lopez Rodriguez, Elena ^a,b   Gay Jordi, Gemma ^c,d   Mucci, Adele ^a,e,f   Lachmann, Nico ^a,e   Serrano Mollar, Anna ^c,d  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Member of the German Center for Lung Research   (Germany)

^c INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^d INSTITUTO DE SALUD CARLOS III   (Spain)

^e Young Research Group Translational Hematology of Congenital Diseases   (Germany)

^f RG Reprogramming and Gene Therapy   (Germany)

Author keywords

Alveolar epithelial type II cells; Alveolar macrophages; Lung fibrosis; Lung surfactant; Pulmonary alveolar proteinosis

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN A1; APOLIPOPROTEIN E; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR ALPHA; JANUS KINASE 2; LOW DENSITY LIPOPROTEIN RECEPTOR; LUNG SURFACTANT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STAT5 PROTEIN; TRANSCRIPTION FACTOR PU 1; UNCLASSIFIED DRUG;

CELL DIFFERENTIATION; CELL TRANSPLANTATION; DRUG METABOLISM; ENZYME PHOSPHORYLATION; HUMAN; INTERNALIZATION; LIPID HOMEOSTASIS; LIPID STORAGE; LIPID TRANSPORT; LUNG ALVEOLUS EPITHELIUM CELL; LUNG ALVEOLUS MACROPHAGE; LUNG ALVEOLUS PROTEINOSIS; LUNG ALVEOLUS SURFACE TENSION; LUNG FIBROSIS; MECHANICAL STRESS; PROTEIN BINDING; PROTEIN LOCALIZATION; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL THERAPY; DISEASES; ENDOCYTOSIS; LUNG; METABOLISM;

ANIMALS; CELL- AND TISSUE-BASED THERAPY; DISEASE; ENDOCYTOSIS; HUMANS; LUNG; MACROPHAGES, ALVEOLAR; PULMONARY SURFACTANTS;

EID: 84992413001     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-016-2520-9     Document Type: Review

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