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Volumn 535, Issue 7611, 2016, Pages 299-302

Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios

(23)  Hoppe, Philipp S a,b   Schwarzfischer, Michael b   Loeffler, Dirk a,b   Kokkaliaris, Konstantinos D a,b   Hilsenbeck, Oliver a,b   Moritz, Nadine b   Endele, Max a,b   Filipczyk, Adam b   Gambardella, Adriana c   Ahmed, Nouraiz a   Etzrodt, Martin a   Coutu, Daniel L a   Rieger, Michael A b   Marr, Carsten b   Strasser, Michael K b   Schauberger, Bernhard b   Burtscher, Ingo d   Ermakova, Olga e   Bürger, Antje b   Lickert, Heiko d,f   more..

e CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR PU 1; GATA1 PROTEIN, MOUSE; ONCOPROTEIN; PROTO-ONCOGENE PROTEIN SPI-1; TRANSACTIVATOR PROTEIN;

EID: 84978698935     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature18320     Document Type: Article
Times cited : (150)

References (38)
  • 1
    • 0025977563 scopus 로고
    • Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1
    • Pevny, L. et al. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature 349, 257-260 (1991).
    • (1991) Nature , vol.349 , pp. 257-260
    • Pevny, L.1
  • 2
    • 0028136726 scopus 로고
    • Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
    • Scott, E. W., Simon, M. C., Anastasi, J., Singh, H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 265, 1573-1577 (1994).
    • (1994) Science , vol.265 , pp. 1573-1577
    • Scott, E.W.1    Simon, M.C.2    Anastasi, J.3    Singh, H.4
  • 3
    • 71449125977 scopus 로고    scopus 로고
    • Forcing cells to change lineages
    • Graf, T., Enver, T. Forcing cells to change lineages. Nature 462, 587-594 (2009).
    • (2009) Nature , vol.462 , pp. 587-594
    • Graf, T.1    Enver, T.2
  • 4
    • 0025876999 scopus 로고
    • Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter
    • Tsai, S. F., Strauss, E., Orkin, S. H. Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter. Genes Dev. 5, 919-931 (1991).
    • (1991) Genes Dev. , vol.5 , pp. 919-931
    • Tsai, S.F.1    Strauss, E.2    Orkin, S.H.3
  • 5
    • 0028826488 scopus 로고
    • PU.1 (Spi-1) autoregulates its expression in myeloid cells
    • Chen, H. et al. PU.1 (Spi-1) autoregulates its expression in myeloid cells. Oncogene 11, 1549-1560 (1995).
    • (1995) Oncogene , vol.11 , pp. 1549-1560
    • Chen, H.1
  • 6
    • 0034667672 scopus 로고    scopus 로고
    • PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding
    • Zhang, P. et al. PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding. Blood 96, 2641-2648 (2000).
    • (2000) Blood , vol.96 , pp. 2641-2648
    • Zhang, P.1
  • 7
    • 0034656393 scopus 로고    scopus 로고
    • GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription
    • Nerlov, C., Querfurth, E., Kulessa, H., Graf, T. GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription. Blood 95, 2543-2551 (2000).
    • (2000) Blood , vol.95 , pp. 2543-2551
    • Nerlov, C.1    Querfurth, E.2    Kulessa, H.3    Graf, T.4
  • 8
    • 0036070180 scopus 로고    scopus 로고
    • Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment
    • Miyamoto, T. et al. Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev. Cell 3, 137-147 (2002).
    • (2002) Dev. Cell , vol.3 , pp. 137-147
    • Miyamoto, T.1
  • 9
    • 34248199004 scopus 로고    scopus 로고
    • Bifurcation dynamics in lineagecommitment in bipotent progenitor cells
    • Huang, S., Guo, Y.-P., May, G., Enver, T. Bifurcation dynamics in lineagecommitment in bipotent progenitor cells. Dev. Biol. 305, 695-713 (2007).
    • (2007) Dev. Biol. , vol.305 , pp. 695-713
    • Huang, S.1    Guo, Y.-P.2    May, G.3    Enver, T.4
  • 10
    • 0037438387 scopus 로고    scopus 로고
    • Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis
    • Akashi, K. et al. Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis. Blood 101, 383-389 (2003).
    • (2003) Blood , vol.101 , pp. 383-389
    • Akashi, K.1
  • 11
    • 34247092922 scopus 로고    scopus 로고
    • Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors
    • Månsson, R. et al. Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors. Immunity 26, 407-419 (2007).
    • (2007) Immunity , vol.26 , pp. 407-419
    • Månsson, R.1
  • 12
    • 84922012748 scopus 로고    scopus 로고
    • Single-cell technologies sharpen up mammalian stem cell research
    • Hoppe, P. S., Coutu, D. L., Schroeder, T. Single-cell technologies sharpen up mammalian stem cell research. Nat. Cell Biol. 16, 919-927 (2014).
    • (2014) Nat. Cell Biol. , vol.16 , pp. 919-927
    • Hoppe, P.S.1    Coutu, D.L.2    Schroeder, T.3
  • 13
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • Akashi, K., Traver, D., Miyamoto, T., Weissman, I. L. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404, 193-197 (2000).
    • (2000) Nature , vol.404 , pp. 193-197
    • Akashi, K.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4
  • 14
    • 39349096526 scopus 로고    scopus 로고
    • Hematopoiesis: An evolving paradigm for stem cell biology
    • Orkin, S. H., Zon, L. I. Hematopoiesis: an evolving paradigm for stem cell biology. Cell 132, 631-644 (2008).
    • (2008) Cell , vol.132 , pp. 631-644
    • Orkin, S.H.1    Zon, L.I.2
  • 15
    • 84922629832 scopus 로고    scopus 로고
    • Quantitative single-cell approaches to stem cell research
    • Etzrodt, M., Endele, M., Schroeder, T. Quantitative single-cell approaches to stem cell research. Cell Stem Cell 15, 546-558 (2014).
    • (2014) Cell Stem Cell , vol.15 , pp. 546-558
    • Etzrodt, M.1    Endele, M.2    Schroeder, T.3
  • 16
    • 84881236410 scopus 로고    scopus 로고
    • Positive feedback between PU.1 and the cell cycle controls myeloid differentiation
    • Kueh, H. Y., Champhekar, A., Nutt, S. L., Elowitz, M. B., Rothenberg, E. V. Positive feedback between PU.1 and the cell cycle controls myeloid differentiation. Science 341, 670-673 (2013).
    • (2013) Science , vol.341 , pp. 670-673
    • Kueh, H.Y.1    Champhekar, A.2    Nutt, S.L.3    Elowitz, M.B.4    Rothenberg, E.V.5
  • 17
    • 33748850636 scopus 로고    scopus 로고
    • Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
    • Kirstetter, P., Anderson, K., Porse, B. T., Jacobsen, S. E. W., Nerlov, C. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat. Immunol. 7, 1048-1056 (2006).
    • (2006) Nat. Immunol. , vol.7 , pp. 1048-1056
    • Kirstetter, P.1    Anderson, K.2    Porse, B.T.3    Jacobsen, S.E.W.4    Nerlov, C.5
  • 18
    • 2642519463 scopus 로고    scopus 로고
    • Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor
    • Rosenbauer, F. et al. Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1. Nat. Genet. 36, 624-630 (2004).
    • (2004) PU.1. Nat. Genet. , vol.36 , pp. 624-630
    • Rosenbauer, F.1
  • 19
    • 0029978734 scopus 로고    scopus 로고
    • Spi-1/PU.1 transgenic mice develop multistep erythroleukemias
    • Moreau-Gachelin, F. et al. Spi-1/PU.1 transgenic mice develop multistep erythroleukemias. Mol. Cell. Biol. 16, 2453-2463 (1996).
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2453-2463
    • Moreau-Gachelin, F.1
  • 20
    • 0037099497 scopus 로고    scopus 로고
    • Transcription factor-mediated lineage switching reveals plasticity in primary committed progenitor cells
    • Heyworth, C., Pearson, S., May, G., Enver, T. Transcription factor-mediated lineage switching reveals plasticity in primary committed progenitor cells. EMBO J. 21, 3770-3781 (2002).
    • (2002) EMBO J. , vol.21 , pp. 3770-3781
    • Heyworth, C.1    Pearson, S.2    May, G.3    Enver, T.4
  • 21
    • 84942981648 scopus 로고    scopus 로고
    • Network plasticity of pluripotency transcription factors in embryonic stem cells
    • Filipczyk, A. et al. Network plasticity of pluripotency transcription factors in embryonic stem cells. Nat. Cell Biol. 17, 1235-1246 (2015).
    • (2015) Nat. Cell Biol. , vol.17 , pp. 1235-1246
    • Filipczyk, A.1
  • 22
    • 34848896359 scopus 로고    scopus 로고
    • Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy
    • Pronk, C. J. H. et al. Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell 1, 428-442 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 428-442
    • Pronk, C.J.H.1
  • 23
    • 34848883146 scopus 로고    scopus 로고
    • Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages
    • Arinobu, Y. et al. Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages. Cell Stem Cell 1, 416-427 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 416-427
    • Arinobu, Y.1
  • 24
    • 22344443951 scopus 로고    scopus 로고
    • Identification of eosinophil lineage-committed progenitors in the murine bone marrow
    • Iwasaki, H. et al. Identification of eosinophil lineage-committed progenitors in the murine bone marrow. J. Exp. Med. 201, 1891-1897 (2005).
    • (2005) J. Exp. Med. , vol.201 , pp. 1891-1897
    • Iwasaki, H.1
  • 25
    • 84923242836 scopus 로고    scopus 로고
    • CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: Redefinition of murine common myeloid progenitor
    • Miyawaki, K. et al. CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: redefinition of murine common myeloid progenitor. Stem Cells 33, 976-987 (2015).
    • (2015) Stem Cells , vol.33 , pp. 976-987
    • Miyawaki, K.1
  • 26
    • 84937023176 scopus 로고    scopus 로고
    • Functionally distinct subsets of lineage-biased multipotent progenitors control blood production in normal and regenerative conditions
    • Pietras, E. M. et al. Functionally distinct subsets of lineage-biased multipotent progenitors control blood production in normal and regenerative conditions. Cell Stem Cell 17, 35-46 (2015).
    • (2015) Cell Stem Cell , vol.17 , pp. 35-46
    • Pietras, E.M.1
  • 28
    • 60149102751 scopus 로고    scopus 로고
    • Continuous single-cell imaging of blood generation from haemogenic endothelium
    • Eilken, H. M., Nishikawa, S., Schroeder, T. Continuous single-cell imaging of blood generation from haemogenic endothelium. Nature 457, 896-900 (2009).
    • (2009) Nature , vol.457 , pp. 896-900
    • Eilken, H.M.1    Nishikawa, S.2    Schroeder, T.3
  • 29
    • 84978402847 scopus 로고    scopus 로고
    • Software tools for single-cell tracking and quantification of cellular and molecular properties
    • Hilsenbeck, O. et al. Software tools for single-cell tracking and quantification of cellular and molecular properties. Nat. Biotechnol. http://dx.doi.org/10.1038/nbt.3626 (2016).
    • (2016) Nat. Biotechnol.
    • Hilsenbeck, O.1
  • 30
    • 84857192635 scopus 로고    scopus 로고
    • FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors
    • Mancini, E. et al. FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors. EMBO J. 31, 351-365 (2012).
    • (2012) EMBO J. , vol.31 , pp. 351-365
    • Mancini, E.1
  • 31
    • 0030954167 scopus 로고    scopus 로고
    • Multilineage gene expression precedes commitment in the hemopoietic system
    • Hu, M. et al. Multilineage gene expression precedes commitment in the hemopoietic system. Genes Dev. 11, 774-785 (1997).
    • (1997) Genes Dev. , vol.11 , pp. 774-785
    • Hu, M.1
  • 32
    • 0037352031 scopus 로고    scopus 로고
    • A highly efficient recombineering-based method for generating conditional knockout mutations
    • Liu, P., Jenkins, N. A., Copeland, N. G. A highly efficient recombineering-based method for generating conditional knockout mutations. Genome Res. 13, 476-484 (2003).
    • (2003) Genome Res. , vol.13 , pp. 476-484
    • Liu, P.1    Jenkins, N.A.2    Copeland, N.G.3
  • 33
    • 11144267737 scopus 로고    scopus 로고
    • Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. Red fluorescent protein
    • Shaner, N. C. et al. Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat. Biotechnol. 22, 1567-1572 (2004).
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1567-1572
    • Shaner, N.C.1
  • 34
    • 0029954688 scopus 로고    scopus 로고
    • Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice
    • Dymecki, S. M. Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice. Proc. Natl Acad. Sci. USA 93, 6191-6196 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 6191-6196
    • Dymecki, S.M.1
  • 35
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel, M. J. et al. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121, 1109-1121 (2005).
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1
  • 36
    • 56549128268 scopus 로고    scopus 로고
    • Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
    • Wilson, A. et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell 135, 1118-1129 (2008).
    • (2008) Cell , vol.135 , pp. 1118-1129
    • Wilson, A.1
  • 38
    • 35748945147 scopus 로고    scopus 로고
    • An error model for protein quantification
    • Kreutz, C. et al. An error model for protein quantification. Bioinformatics 23, 2747-2753 (2007).
    • (2007) Bioinformatics , vol.23 , pp. 2747-2753
    • Kreutz, C.1


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