-
1
-
-
84905754409
-
Microfluidic organs-on-chips
-
Bhatia, S.N., Ingber, D.E., Microfluidic organs-on-chips. Nat. Biotechnol. 32 (2014), 760–772.
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 760-772
-
-
Bhatia, S.N.1
Ingber, D.E.2
-
2
-
-
0037133954
-
PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2
-
Bhunia, A.K., Piontek, K., Boletta, A., Liu, L., Qian, F., Xu, P.N., Germino, F.J., Germino, G.G., PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2. Cell 109 (2002), 157–168.
-
(2002)
Cell
, vol.109
, pp. 157-168
-
-
Bhunia, A.K.1
Piontek, K.2
Boletta, A.3
Liu, L.4
Qian, F.5
Xu, P.N.6
Germino, F.J.7
Germino, G.G.8
-
3
-
-
0037836057
-
Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure
-
Bonventre, J.V., Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure. J. Am. Soc. Nephrol. 14:Suppl 1 (2003), S55–S61.
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. S55-S61
-
-
Bonventre, J.V.1
-
4
-
-
56249098350
-
Characterisation of human tubular cell monolayers as a model of proximal tubular xenobiotic handling
-
Brown, C.D., Sayer, R., Windass, A.S., Haslam, I.S., De Broe, M.E., D'Haese, P.C., Verhulst, A., Characterisation of human tubular cell monolayers as a model of proximal tubular xenobiotic handling. Toxicol. Appl. Pharmacol. 233 (2008), 428–438.
-
(2008)
Toxicol. Appl. Pharmacol.
, vol.233
, pp. 428-438
-
-
Brown, C.D.1
Sayer, R.2
Windass, A.S.3
Haslam, I.S.4
De Broe, M.E.5
D'Haese, P.C.6
Verhulst, A.7
-
5
-
-
84908480034
-
A molecular switch for the orientation of epithelial cell polarization
-
Bryant, D.M., Roignot, J., Datta, A., Overeem, A.W., Kim, M., Yu, W., Peng, X., Eastburn, D.J., Ewald, A.J., Werb, Z., Mostov, K.E., A molecular switch for the orientation of epithelial cell polarization. Dev. Cell 31 (2014), 171–187.
-
(2014)
Dev. Cell
, vol.31
, pp. 171-187
-
-
Bryant, D.M.1
Roignot, J.2
Datta, A.3
Overeem, A.W.4
Kim, M.5
Yu, W.6
Peng, X.7
Eastburn, D.J.8
Ewald, A.J.9
Werb, Z.10
Mostov, K.E.11
-
6
-
-
84960120449
-
Fluorescence-based transport assays revisited in a human renal proximal tubule cell line
-
Caetano-Pinto, P., Janssen, M.J., Gijzen, L., Verscheijden, L., Wilmer, M.J., Masereeuw, R., Fluorescence-based transport assays revisited in a human renal proximal tubule cell line. Mol. Pharm. 13 (2016), 933–944.
-
(2016)
Mol. Pharm.
, vol.13
, pp. 933-944
-
-
Caetano-Pinto, P.1
Janssen, M.J.2
Gijzen, L.3
Verscheijden, L.4
Wilmer, M.J.5
Masereeuw, R.6
-
7
-
-
26944476343
-
Molecular identification of canine podocalyxin-like protein 1 as a renal tubulogenic regulator
-
Cheng, H.Y., Lin, Y.Y., Yu, C.Y., Chen, J.Y., Shen, K.F., Lin, W.L., Liao, H.K., Chen, Y.J., Liu, C.H., Pang, V.F., Jou, T.S., Molecular identification of canine podocalyxin-like protein 1 as a renal tubulogenic regulator. J. Am. Soc. Nephrol. 16 (2005), 1612–1622.
-
(2005)
J. Am. Soc. Nephrol.
, vol.16
, pp. 1612-1622
-
-
Cheng, H.Y.1
Lin, Y.Y.2
Yu, C.Y.3
Chen, J.Y.4
Shen, K.F.5
Lin, W.L.6
Liao, H.K.7
Chen, Y.J.8
Liu, C.H.9
Pang, V.F.10
Jou, T.S.11
-
8
-
-
84862773705
-
Transcriptomic analysis of the effect of ifosfamide on MDCK cells cultivated in microfluidic biochips
-
Choucha Snouber, L., Jacques, S., Monge, M., Legallais, C., Leclerc, E., Transcriptomic analysis of the effect of ifosfamide on MDCK cells cultivated in microfluidic biochips. Genomics 100 (2012), 27–34.
-
(2012)
Genomics
, vol.100
, pp. 27-34
-
-
Choucha Snouber, L.1
Jacques, S.2
Monge, M.3
Legallais, C.4
Leclerc, E.5
-
9
-
-
84874092834
-
Species differences in drug transporters and implications for translating preclinical findings to humans
-
Chu, X., Bleasby, K., Evers, R., Species differences in drug transporters and implications for translating preclinical findings to humans. Expert Opin. Drug Metab. Toxicol. 9 (2013), 237–252.
-
(2013)
Expert Opin. Drug Metab. Toxicol.
, vol.9
, pp. 237-252
-
-
Chu, X.1
Bleasby, K.2
Evers, R.3
-
10
-
-
28244486151
-
Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2
-
Ciarimboli, G., Ludwig, T., Lang, D., Pavenstadt, H., Koepsell, H., Piechota, H.J., Haier, J., Jaehde, U., Zisowsky, J., Schlatter, E., Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2. Am. J. Pathol. 167 (2005), 1477–1484.
-
(2005)
Am. J. Pathol.
, vol.167
, pp. 1477-1484
-
-
Ciarimboli, G.1
Ludwig, T.2
Lang, D.3
Pavenstadt, H.4
Koepsell, H.5
Piechota, H.J.6
Haier, J.7
Jaehde, U.8
Zisowsky, J.9
Schlatter, E.10
-
11
-
-
84926227818
-
Cell-cell interactions driving kidney morphogenesis
-
Combes, A.N., Davies, J.A., Little, M.H., Cell-cell interactions driving kidney morphogenesis. Curr. Top. Dev. Biol. 112 (2015), 467–508.
-
(2015)
Curr. Top. Dev. Biol.
, vol.112
, pp. 467-508
-
-
Combes, A.N.1
Davies, J.A.2
Little, M.H.3
-
12
-
-
0006241557
-
Pathophysiology of nephrotoxic cell injury
-
R.W. Schrier P.A. Philadelphia Lippincott Williams and Wilkinson
-
Cummings, B.S., Schnellmann, R.G., Pathophysiology of nephrotoxic cell injury. Schrier, R.W., Philadelphia, P.A., (eds.) Diseases of the Kindey and Urogenital Tract, 2001, Lippincott Williams and Wilkinson, 1071–1136.
-
(2001)
Diseases of the Kindey and Urogenital Tract
, pp. 1071-1136
-
-
Cummings, B.S.1
Schnellmann, R.G.2
-
13
-
-
84962429248
-
-
Delling et al., Nature 2016;
-
Delling et al., Nature 2016; http://dx.doi.org/10.1038/nature17426.
-
-
-
-
14
-
-
84875048928
-
Bioengineered 3D human kidney tissue, a platform for the determination of nephrotoxicity
-
DesRochers, T.M., Suter, L., Roth, A., Kaplan, D.L., Bioengineered 3D human kidney tissue, a platform for the determination of nephrotoxicity. PloS One, 8, 2013, e59219.
-
(2013)
PloS One
, vol.8
, pp. e59219
-
-
DesRochers, T.M.1
Suter, L.2
Roth, A.3
Kaplan, D.L.4
-
15
-
-
0032403465
-
Rapid prototyping of microfluidic systems in poly(dimethylsiloxane)
-
Duffy, D.C., McDonald, J.C., Schueller, O.J., Whitesides, G.M., Rapid prototyping of microfluidic systems in poly(dimethylsiloxane). Anal. Chem. 70 (1998), 4974–4984.
-
(1998)
Anal. Chem.
, vol.70
, pp. 4974-4984
-
-
Duffy, D.C.1
McDonald, J.C.2
Schueller, O.J.3
Whitesides, G.M.4
-
16
-
-
0023947834
-
Influence of the hepatic drug-metabolizing enzyme-inducer phenobarbitone on cyclosporine nephrotoxicity and hepatotoxicity in renal-allografted rats
-
Duncan, J.I., Heys, S.D., Thomson, A.W., Simpson, J.G., Whiting, P.H., Influence of the hepatic drug-metabolizing enzyme-inducer phenobarbitone on cyclosporine nephrotoxicity and hepatotoxicity in renal-allografted rats. Transplantation 45 (1988), 693–697.
-
(1988)
Transplantation
, vol.45
, pp. 693-697
-
-
Duncan, J.I.1
Heys, S.D.2
Thomson, A.W.3
Simpson, J.G.4
Whiting, P.H.5
-
17
-
-
84863528247
-
Normal and pathologic concentrations of uremic toxins
-
Duranton, F., Cohen, G., De Smet, R., Rodriguez, M., Jankowski, J., Vanholder, R., Argiles, A., Normal and pathologic concentrations of uremic toxins. J. Am. Soc. Nephrol. 23 (2012), 1258–1270.
-
(2012)
J. Am. Soc. Nephrol.
, vol.23
, pp. 1258-1270
-
-
Duranton, F.1
Cohen, G.2
De Smet, R.3
Rodriguez, M.4
Jankowski, J.5
Vanholder, R.6
Argiles, A.7
-
18
-
-
34047212211
-
Mitochondria are the major targets in albumin-induced apoptosis in proximal tubule cells
-
Erkan, E., Devarajan, P., Schwartz, G.J., Mitochondria are the major targets in albumin-induced apoptosis in proximal tubule cells. J. Am. Soc. Nephrol. 18 (2007), 1199–1208.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 1199-1208
-
-
Erkan, E.1
Devarajan, P.2
Schwartz, G.J.3
-
19
-
-
84855930703
-
Albumin handling by renal tubular epithelial cells in a microfluidic bioreactor
-
Ferrell, N., Ricci, K.B., Groszek, J., Marmerstein, J.T., Fissell, W.H., Albumin handling by renal tubular epithelial cells in a microfluidic bioreactor. Biotechnol. Bioeng. 109 (2012), 797–803.
-
(2012)
Biotechnol. Bioeng.
, vol.109
, pp. 797-803
-
-
Ferrell, N.1
Ricci, K.B.2
Groszek, J.3
Marmerstein, J.T.4
Fissell, W.H.5
-
20
-
-
79952370958
-
Renal replacement therapy review: past, present and future
-
Fleming, G.M., Renal replacement therapy review: past, present and future. Organogenesis 7 (2011), 2–12.
-
(2011)
Organogenesis
, vol.7
, pp. 2-12
-
-
Fleming, G.M.1
-
21
-
-
0033083552
-
Molding of deep polydimethylsiloxane microstructures for microfluidics and biological applications
-
Folch, A., Ayon, A., Hurtado, O., Schmidt, M.A., Toner, M., Molding of deep polydimethylsiloxane microstructures for microfluidics and biological applications. J. Biomech. Eng. 121 (1999), 28–34.
-
(1999)
J. Biomech. Eng.
, vol.121
, pp. 28-34
-
-
Folch, A.1
Ayon, A.2
Hurtado, O.3
Schmidt, M.A.4
Toner, M.5
-
22
-
-
84945246096
-
Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
-
Freedman, B.S., Brooks, C.R., Lam, A.Q., Fu, H., Morizane, R., Agrawal, V., Saad, A.F., Li, M.K., Hughes, M.R., Werff, R.V., Peters, D.T., Lu, J., Baccei, A., Siedlecki, A.M., Valerius, M.T., Musunuru, K., McNagny, K.M., Steinman, T.I., Zhou, J., Lerou, P.H., Bonventre, J.V., Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids. Nat. Commun., 6, 2015, 8715.
-
(2015)
Nat. Commun.
, vol.6
, pp. 8715
-
-
Freedman, B.S.1
Brooks, C.R.2
Lam, A.Q.3
Fu, H.4
Morizane, R.5
Agrawal, V.6
Saad, A.F.7
Li, M.K.8
Hughes, M.R.9
Werff, R.V.10
Peters, D.T.11
Lu, J.12
Baccei, A.13
Siedlecki, A.M.14
Valerius, M.T.15
Musunuru, K.16
McNagny, K.M.17
Steinman, T.I.18
Zhou, J.19
Lerou, P.H.20
Bonventre, J.V.21
more..
-
23
-
-
84876855574
-
Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients
-
Gorvin, C.M., Wilmer, M.J., Piret, S.E., Harding, B., van den Heuvel, L.P., Wrong, O., Jat, P.S., Lippiat, J.D., Levtchenko, E.N., Thakker, R.V., Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients. Proc. Natl. Acad. Sci. USA 110 (2013), 7014–7019.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 7014-7019
-
-
Gorvin, C.M.1
Wilmer, M.J.2
Piret, S.E.3
Harding, B.4
van den Heuvel, L.P.5
Wrong, O.6
Jat, P.S.7
Lippiat, J.D.8
Levtchenko, E.N.9
Thakker, R.V.10
-
24
-
-
0034700483
-
Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents
-
Hanaoka, K., Qian, F., Boletta, A., Bhunia, A.K., Piontek, K., Tsiokas, L., Sukhatme, V.P., Guggino, W.B., Germino, G.G., Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents. Nature 408 (2000), 990–994.
-
(2000)
Nature
, vol.408
, pp. 990-994
-
-
Hanaoka, K.1
Qian, F.2
Boletta, A.3
Bhunia, A.K.4
Piontek, K.5
Tsiokas, L.6
Sukhatme, V.P.7
Guggino, W.B.8
Germino, G.G.9
-
25
-
-
0034008388
-
Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1
-
Ho, E.S., Lin, D.C., Mendel, D.B., Cihlar, T., Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1. J. Am. Soc. Nephrol. 11 (2000), 383–393.
-
(2000)
J. Am. Soc. Nephrol.
, vol.11
, pp. 383-393
-
-
Ho, E.S.1
Lin, D.C.2
Mendel, D.B.3
Cihlar, T.4
-
26
-
-
84949024195
-
Organic anion transporter 1 is inhibited by multiple mechanisms and shows a transport mode independent of exchange
-
Hotchkiss, A.G., Gao, T., Khan, U., Berrigan, L., Li, M., Ingraham, L., Pelis, R.M., Organic anion transporter 1 is inhibited by multiple mechanisms and shows a transport mode independent of exchange. Drug Metab. Dispos. 43 (2015), 1847–1854.
-
(2015)
Drug Metab. Dispos.
, vol.43
, pp. 1847-1854
-
-
Hotchkiss, A.G.1
Gao, T.2
Khan, U.3
Berrigan, L.4
Li, M.5
Ingraham, L.6
Pelis, R.M.7
-
27
-
-
77954038080
-
Reconstituting organ-level lung functions on a chip
-
Huh, D., Matthews, B.D., Mammoto, A., Montoya-Zavala, M., Hsin, H.Y., Ingber, D.E., Reconstituting organ-level lung functions on a chip. Science 328 (2010), 1662–1668.
-
(2010)
Science
, vol.328
, pp. 1662-1668
-
-
Huh, D.1
Matthews, B.D.2
Mammoto, A.3
Montoya-Zavala, M.4
Hsin, H.Y.5
Ingber, D.E.6
-
28
-
-
84894278217
-
The bioartificial kidney: current status and future promise
-
Humes, H.D., Buffington, D., Westover, A.J., Roy, S., Fissell, W.H., The bioartificial kidney: current status and future promise. Pediatr. Nephrol. 29 (2014), 343–351.
-
(2014)
Pediatr. Nephrol.
, vol.29
, pp. 343-351
-
-
Humes, H.D.1
Buffington, D.2
Westover, A.J.3
Roy, S.4
Fissell, W.H.5
-
29
-
-
0029736790
-
Tubulogenesis from isolated single cells of adult mammalian kidney: clonal analysis with a recombinant retrovirus
-
Humes, H.D., Krauss, J.C., Cieslinski, D.A., Funke, A.J., Tubulogenesis from isolated single cells of adult mammalian kidney: clonal analysis with a recombinant retrovirus. Am. J. Physiol. 271 (1996), F42–F49.
-
(1996)
Am. J. Physiol.
, vol.271
, pp. F42-F49
-
-
Humes, H.D.1
Krauss, J.C.2
Cieslinski, D.A.3
Funke, A.J.4
-
30
-
-
0033065041
-
Tissue engineering of a bioartificial renal tubule assist device: in vitro transport and metabolic characteristics
-
Humes, H.D., MacKay, S.M., Funke, A.J., Buffington, D.A., Tissue engineering of a bioartificial renal tubule assist device: in vitro transport and metabolic characteristics. Kidney Int. 55 (1999), 2502–2514.
-
(1999)
Kidney Int.
, vol.55
, pp. 2502-2514
-
-
Humes, H.D.1
MacKay, S.M.2
Funke, A.J.3
Buffington, D.A.4
-
31
-
-
4644247004
-
Initial clinical results of the bioartificial kidney containing human cells in ICU patients with acute renal failure
-
Humes, H.D., Weitzel, W.F., Bartlett, R.H., Swaniker, F.C., Paganini, E.P., Luderer, J.R., Sobota, J., Initial clinical results of the bioartificial kidney containing human cells in ICU patients with acute renal failure. Kidney Int. 66 (2004), 1578–1588.
-
(2004)
Kidney Int.
, vol.66
, pp. 1578-1588
-
-
Humes, H.D.1
Weitzel, W.F.2
Bartlett, R.H.3
Swaniker, F.C.4
Paganini, E.P.5
Luderer, J.R.6
Sobota, J.7
-
32
-
-
79959336759
-
Repair of injured proximal tubule does not involve specialized progenitors
-
Humphreys, B.D., Czerniak, S., DiRocco, D.P., Hasnain, W., Cheema, R., Bonventre, J.V., Repair of injured proximal tubule does not involve specialized progenitors. Proc. Natl. Acad. Sci. USA 108 (2011), 9226–9231.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 9226-9231
-
-
Humphreys, B.D.1
Czerniak, S.2
DiRocco, D.P.3
Hasnain, W.4
Cheema, R.5
Bonventre, J.V.6
-
33
-
-
39749172401
-
Intrinsic epithelial cells repair the kidney after injury
-
Humphreys, B.D., Valerius, M.T., Kobayashi, A., Mugford, J.W., Soeung, S., Duffield, J.S., McMahon, A.P., Bonventre, J.V., Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell 2 (2008), 284–291.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 284-291
-
-
Humphreys, B.D.1
Valerius, M.T.2
Kobayashi, A.3
Mugford, J.W.4
Soeung, S.5
Duffield, J.S.6
McMahon, A.P.7
Bonventre, J.V.8
-
34
-
-
84901434770
-
A plasma concentration of alpha-ketoglutarate influences the kinetic interaction of ligands with organic anion transporter 1
-
Ingraham, L., Li, M., Renfro, J.L., Parker, S., Vapurcuyan, A., Hanna, I., Pelis, R.M., A plasma concentration of alpha-ketoglutarate influences the kinetic interaction of ligands with organic anion transporter 1. Mol. Pharmacol. 86 (2014), 86–95.
-
(2014)
Mol. Pharmacol.
, vol.86
, pp. 86-95
-
-
Ingraham, L.1
Li, M.2
Renfro, J.L.3
Parker, S.4
Vapurcuyan, A.5
Hanna, I.6
Pelis, R.M.7
-
35
-
-
1642390921
-
Primary cilia of human endothelial cells disassemble under laminar shear stress
-
Iomini, C., Tejada, K., Mo, W., Vaananen, H., Piperno, G., Primary cilia of human endothelial cells disassemble under laminar shear stress. J. Cell Biol. 164 (2004), 811–817.
-
(2004)
J. Cell Biol.
, vol.164
, pp. 811-817
-
-
Iomini, C.1
Tejada, K.2
Mo, W.3
Vaananen, H.4
Piperno, G.5
-
36
-
-
84926143734
-
Endo-lysosomal dysfunction in human proximal tubular epithelial cells deficient for lysosomal cystine transporter cystinosin
-
Ivanova, E.A., De Leo, M.G., Van Den Heuvel, L., Pastore, A., Dijkman, H., De Matteis, M.A., Levtchenko, E.N., Endo-lysosomal dysfunction in human proximal tubular epithelial cells deficient for lysosomal cystine transporter cystinosin. PloS One, 10, 2015, e0120998.
-
(2015)
PloS One
, vol.10
, pp. e0120998
-
-
Ivanova, E.A.1
De Leo, M.G.2
Van Den Heuvel, L.3
Pastore, A.4
Dijkman, H.5
De Matteis, M.A.6
Levtchenko, E.N.7
-
37
-
-
70349618911
-
The nephrotoxic effects of HAART
-
Izzedine, H., Harris, M., Perazella, M.A., The nephrotoxic effects of HAART. Nat. Rev. Nephrol. 5 (2009), 563–573.
-
(2009)
Nat. Rev. Nephrol.
, vol.5
, pp. 563-573
-
-
Izzedine, H.1
Harris, M.2
Perazella, M.A.3
-
38
-
-
84882590738
-
Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment
-
Jang, K.J., Mehr, A.P., Hamilton, G.A., McPartlin, L.A., Chung, S., Suh, K.Y., Ingber, D.E., Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment. Integr. Biol. 5 (2013), 1119–1129.
-
(2013)
Integr. Biol.
, vol.5
, pp. 1119-1129
-
-
Jang, K.J.1
Mehr, A.P.2
Hamilton, G.A.3
McPartlin, L.A.4
Chung, S.5
Suh, K.Y.6
Ingber, D.E.7
-
39
-
-
77951884924
-
A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells
-
Jang, K.J., Suh, K.Y., A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells. Lab Chip 10 (2010), 36–42.
-
(2010)
Lab Chip
, vol.10
, pp. 36-42
-
-
Jang, K.J.1
Suh, K.Y.2
-
40
-
-
84933055140
-
On-chip three-dimensional cell culture in phaseguides improves hepatocyte functions in vitro
-
Jang, M., Neuzil, P., Volk, T., Manz, A., Kleber, A., On-chip three-dimensional cell culture in phaseguides improves hepatocyte functions in vitro. Biomicrofluidics, 9, 2015, 034113.
-
(2015)
Biomicrofluidics
, vol.9
, pp. 034113
-
-
Jang, M.1
Neuzil, P.2
Volk, T.3
Manz, A.4
Kleber, A.5
-
41
-
-
84947079585
-
Human proximal tubule epithelial cells cultured on hollow fibers: living membranes that actively transport organic cations
-
Jansen, J., De Napoli, I.E., Fedecostante, M., Schophuizen, C.M., Chevtchik, N.V., Wilmer, M.J., van Asbeck, A.H., Croes, H.J., Pertijs, J.C., Wetzels, J.F., Hilbrands, L.B., van den Heuvel, L.P., Hoenderop, J.G., Stamatialis, D., Masereeuw, R., Human proximal tubule epithelial cells cultured on hollow fibers: living membranes that actively transport organic cations. Sci. Rep., 5, 2015, 16702.
-
(2015)
Sci. Rep.
, vol.5
, pp. 16702
-
-
Jansen, J.1
De Napoli, I.E.2
Fedecostante, M.3
Schophuizen, C.M.4
Chevtchik, N.V.5
Wilmer, M.J.6
van Asbeck, A.H.7
Croes, H.J.8
Pertijs, J.C.9
Wetzels, J.F.10
Hilbrands, L.B.11
van den Heuvel, L.P.12
Hoenderop, J.G.13
Stamatialis, D.14
Masereeuw, R.15
-
42
-
-
84921984209
-
Biotechnological challenges of bioartificial kidney engineering
-
Jansen, J., Fedecostante, M., Wilmer, M.J., van den Heuvel, L.P., Hoenderop, J.G., Masereeuw, R., Biotechnological challenges of bioartificial kidney engineering. Biotechnol. Adv. 32 (2014), 1317–1327.
-
(2014)
Biotechnol. Adv.
, vol.32
, pp. 1317-1327
-
-
Jansen, J.1
Fedecostante, M.2
Wilmer, M.J.3
van den Heuvel, L.P.4
Hoenderop, J.G.5
Masereeuw, R.6
-
43
-
-
85027933239
-
The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule
-
Jenkinson, S.E., Chung, G.W., van Loon, E., Bakar, N.S., Dalzell, A.M., Brown, C.D., The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule. Pflug. Arch.: Eur. J. Physiol. 464 (2012), 601–611.
-
(2012)
Pflug. Arch.: Eur. J. Physiol.
, vol.464
, pp. 601-611
-
-
Jenkinson, S.E.1
Chung, G.W.2
van Loon, E.3
Bakar, N.S.4
Dalzell, A.M.5
Brown, C.D.6
-
44
-
-
84862207235
-
Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow
-
Kim, H.J., Huh, D., Hamilton, G., Ingber, D.E., Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow. Lab Chip 12 (2012), 2165–2174.
-
(2012)
Lab Chip
, vol.12
, pp. 2165-2174
-
-
Kim, H.J.1
Huh, D.2
Hamilton, G.3
Ingber, D.E.4
-
45
-
-
23744449992
-
Matrigel: basement membrane matrix with biological activity
-
Kleinman, H.K., Martin, G.R., Matrigel: basement membrane matrix with biological activity. Semin. Cancer Biol. 15 (2005), 378–386.
-
(2005)
Semin. Cancer Biol.
, vol.15
, pp. 378-386
-
-
Kleinman, H.K.1
Martin, G.R.2
-
46
-
-
84875181483
-
The SLC22 family with transporters of organic cations, anions and zwitterions
-
Koepsell, H., The SLC22 family with transporters of organic cations, anions and zwitterions. Mol. Asp. Med. 34 (2013), 413–435.
-
(2013)
Mol. Asp. Med.
, vol.34
, pp. 413-435
-
-
Koepsell, H.1
-
47
-
-
84918790597
-
Akt recruits Dab2 to albumin endocytosis in the proximal tubule
-
Koral, K., Li, H., Ganesh, N., Birnbaum, M.J., Hallows, K.R., Erkan, E., Akt recruits Dab2 to albumin endocytosis in the proximal tubule. Am. J. Physiol. Ren. Physiol. 307 (2014), F1380–F1389.
-
(2014)
Am. J. Physiol. Ren. Physiol.
, vol.307
, pp. F1380-F1389
-
-
Koral, K.1
Li, H.2
Ganesh, N.3
Birnbaum, M.J.4
Hallows, K.R.5
Erkan, E.6
-
48
-
-
84925002669
-
Transport of organic anions and cations in murine embryonic kidney development and in serially-reaggregated engineered kidneys
-
Lawrence, M.L., Chang, C.H., Davies, J.A., Transport of organic anions and cations in murine embryonic kidney development and in serially-reaggregated engineered kidneys. Sci. Rep., 5, 2015, 9092.
-
(2015)
Sci. Rep.
, vol.5
, pp. 9092
-
-
Lawrence, M.L.1
Chang, C.H.2
Davies, J.A.3
-
49
-
-
77949897625
-
ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells
-
Lima, W.R., Parreira, K.S., Devuyst, O., Caplanusi, A., N'Kuli, F., Marien, B., Van Der Smissen, P., Alves, P.M., Verroust, P., Christensen, E.I., Terzi, F., Matter, K., Balda, M.S., Pierreux, C.E., Courtoy, P.J., ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells. J. Am. Soc. Nephrol. 21 (2010), 478–488.
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 478-488
-
-
Lima, W.R.1
Parreira, K.S.2
Devuyst, O.3
Caplanusi, A.4
N'Kuli, F.5
Marien, B.6
Van Der Smissen, P.7
Alves, P.M.8
Verroust, P.9
Christensen, E.I.10
Terzi, F.11
Matter, K.12
Balda, M.S.13
Pierreux, C.E.14
Courtoy, P.J.15
-
50
-
-
29744470060
-
Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease
-
Low, S.H., Vasanth, S., Larson, C.H., Mukherjee, S., Sharma, N., Kinter, M.T., Kane, M.E., Obara, T., Weimbs, T., Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease. Dev. Cell 10 (2006), 57–69.
-
(2006)
Dev. Cell
, vol.10
, pp. 57-69
-
-
Low, S.H.1
Vasanth, S.2
Larson, C.H.3
Mukherjee, S.4
Sharma, N.5
Kinter, M.T.6
Kane, M.E.7
Obara, T.8
Weimbs, T.9
-
51
-
-
41449087759
-
Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis
-
Martin-Belmonte, F., Yu, W., Rodriguez-Fraticelli, A.E., Ewald, A.J., Werb, Z., Alonso, M.A., Mostov, K., Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis. Curr. Biol. 18 (2008), 507–513.
-
(2008)
Curr. Biol.
, vol.18
, pp. 507-513
-
-
Martin-Belmonte, F.1
Yu, W.2
Rodriguez-Fraticelli, A.E.3
Ewald, A.J.4
Werb, Z.5
Alonso, M.A.6
Mostov, K.7
-
52
-
-
84930959624
-
A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
-
Maschmeyer, I., Lorenz, A.K., Schimek, K., Hasenberg, T., Ramme, A.P., Hubner, J., Lindner, M., Drewell, C., Bauer, S., Thomas, A., Sambo, N.S., Sonntag, F., Lauster, R., Marx, U., A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents. Lab Chip 15 (2015), 2688–2699.
-
(2015)
Lab Chip
, vol.15
, pp. 2688-2699
-
-
Maschmeyer, I.1
Lorenz, A.K.2
Schimek, K.3
Hasenberg, T.4
Ramme, A.P.5
Hubner, J.6
Lindner, M.7
Drewell, C.8
Bauer, S.9
Thomas, A.10
Sambo, N.S.11
Sonntag, F.12
Lauster, R.13
Marx, U.14
-
53
-
-
15844385078
-
PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein
-
Mochizuki, T., Wu, G., Hayashi, T., Xenophontos, S.L., Veldhuisen, B., Saris, J.J., Reynolds, D.M., Cai, Y., Gabow, P.A., Pierides, A., Kimberling, W.J., Breuning, M.H., Deltas, C.C., Peters, D.J., Somlo, S., PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein. Science 272 (1996), 1339–1342.
-
(1996)
Science
, vol.272
, pp. 1339-1342
-
-
Mochizuki, T.1
Wu, G.2
Hayashi, T.3
Xenophontos, S.L.4
Veldhuisen, B.5
Saris, J.J.6
Reynolds, D.M.7
Cai, Y.8
Gabow, P.A.9
Pierides, A.10
Kimberling, W.J.11
Breuning, M.H.12
Deltas, C.C.13
Peters, D.J.14
Somlo, S.15
-
54
-
-
0037317302
-
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
-
Nauli, S.M., Alenghat, F.J., Luo, Y., Williams, E., Vassilev, P., Li, X., Elia, A.E., Lu, W., Brown, E.M., Quinn, S.J., Ingber, D.E., Zhou, J., Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat. Genet. 33 (2003), 129–137.
-
(2003)
Nat. Genet.
, vol.33
, pp. 129-137
-
-
Nauli, S.M.1
Alenghat, F.J.2
Luo, Y.3
Williams, E.4
Vassilev, P.5
Li, X.6
Elia, A.E.7
Lu, W.8
Brown, E.M.9
Quinn, S.J.10
Ingber, D.E.11
Zhou, J.12
-
55
-
-
84973162078
-
Megalin and cubilin in proximal tubule protein reabsorption: from experimental models to human disease
-
Nielsen, R., Christensen, E.I., Birn, H., Megalin and cubilin in proximal tubule protein reabsorption: from experimental models to human disease. Kidney Int. 89 (2016), 58–67.
-
(2016)
Kidney Int.
, vol.89
, pp. 58-67
-
-
Nielsen, R.1
Christensen, E.I.2
Birn, H.3
-
56
-
-
84959541935
-
A human renal proximal tubule cell line with stable organic anion transporter 1 and 3 expression predictive for antiviral-induced toxicity
-
Nieskens, T.T., Peters, J.G., Schreurs, M.J., Smits, N., Woestenenk, R., Jansen, K., van der Made, T.K., Roring, M., Hilgendorf, C., Wilmer, M.J., Masereeuw, R., A human renal proximal tubule cell line with stable organic anion transporter 1 and 3 expression predictive for antiviral-induced toxicity. AAPS J. 18 (2016), 465–475.
-
(2016)
AAPS J.
, vol.18
, pp. 465-475
-
-
Nieskens, T.T.1
Peters, J.G.2
Schreurs, M.J.3
Smits, N.4
Woestenenk, R.5
Jansen, K.6
van der Made, T.K.7
Roring, M.8
Hilgendorf, C.9
Wilmer, M.J.10
Masereeuw, R.11
-
57
-
-
84946733480
-
Handling of drugs, metabolites, and uremic toxins by kidney proximal tubule drug transporters
-
Nigam, S.K., Wu, W., Bush, K.T., Hoenig, M.P., Blantz, R.C., Bhatnagar, V., Handling of drugs, metabolites, and uremic toxins by kidney proximal tubule drug transporters. Clin. J. Am. Soc. Nephrol. 10 (2015), 2039–2049.
-
(2015)
Clin. J. Am. Soc. Nephrol.
, vol.10
, pp. 2039-2049
-
-
Nigam, S.K.1
Wu, W.2
Bush, K.T.3
Hoenig, M.P.4
Blantz, R.C.5
Bhatnagar, V.6
-
58
-
-
77449119885
-
A microfluidic hepatic coculture platform for cell-based drug metabolism studies
-
Novik, E., Maguire, T.J., Chao, P., Cheng, K.C., Yarmush, M.L., A microfluidic hepatic coculture platform for cell-based drug metabolism studies. Biochem. Pharmacol. 79 (2010), 1036–1044.
-
(2010)
Biochem. Pharmacol.
, vol.79
, pp. 1036-1044
-
-
Novik, E.1
Maguire, T.J.2
Chao, P.3
Cheng, K.C.4
Yarmush, M.L.5
-
59
-
-
0021681724
-
The metabolism and nephrotoxicity of tetrafluoroethylene in the rat
-
Odum, J., Green, T., The metabolism and nephrotoxicity of tetrafluoroethylene in the rat. Toxicol. Appl. Pharmacol. 76 (1984), 306–318.
-
(1984)
Toxicol. Appl. Pharmacol.
, vol.76
, pp. 306-318
-
-
Odum, J.1
Green, T.2
-
60
-
-
44349116202
-
Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia
-
Patel, V., Li, L., Cobo-Stark, P., Shao, X., Somlo, S., Lin, F., Igarashi, P., Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia. Hum. Mol. Genet. 17 (2008), 1578–1590.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 1578-1590
-
-
Patel, V.1
Li, L.2
Cobo-Stark, P.3
Shao, X.4
Somlo, S.5
Lin, F.6
Igarashi, P.7
-
61
-
-
0035823636
-
Properties and regulation of organic cation transport in freshly isolated human proximal tubules
-
Pietig, G., Mehrens, T., Hirsch, J.R., Cetinkaya, I., Piechota, H., Schlatter, E., Properties and regulation of organic cation transport in freshly isolated human proximal tubules. J. Biol. Chem. 276 (2001), 33741–33746.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33741-33746
-
-
Pietig, G.1
Mehrens, T.2
Hirsch, J.R.3
Cetinkaya, I.4
Piechota, H.5
Schlatter, E.6
-
62
-
-
0035011872
-
Role of the basement membrane in tumor cell dormancy and cytotoxic resistance
-
Pogany, G., Timar, F., Olah, J., Harisi, R., Polony, G., Paku, S., Bocsi, J., Jeney, A., Laurie, G.W., Role of the basement membrane in tumor cell dormancy and cytotoxic resistance. Oncology 60 (2001), 274–281.
-
(2001)
Oncology
, vol.60
, pp. 274-281
-
-
Pogany, G.1
Timar, F.2
Olah, J.3
Harisi, R.4
Polony, G.5
Paku, S.6
Bocsi, J.7
Jeney, A.8
Laurie, G.W.9
-
63
-
-
63749105226
-
mTOR and the control of whole body metabolism
-
Polak, P., Hall, M.N., mTOR and the control of whole body metabolism. Curr. Opin. Cell Biol. 21 (2009), 209–218.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 209-218
-
-
Polak, P.1
Hall, M.N.2
-
64
-
-
84922266315
-
The primary cilium as sensor of fluid flow: new building blocks to the model. A review in the theme: cell signaling: proteins, pathways and mechanisms
-
Praetorius, H.A., The primary cilium as sensor of fluid flow: new building blocks to the model. A review in the theme: cell signaling: proteins, pathways and mechanisms. Am. J. Physiol. Cell Physiol. 308 (2015), C198–C208.
-
(2015)
Am. J. Physiol. Cell Physiol.
, vol.308
, pp. C198-C208
-
-
Praetorius, H.A.1
-
65
-
-
0035498717
-
Bending the MDCK cell primary cilium increases intracellular calcium
-
Praetorius, H.A., Spring, K.R., Bending the MDCK cell primary cilium increases intracellular calcium. J. Membr. Biol. 184 (2001), 71–79.
-
(2001)
J. Membr. Biol.
, vol.184
, pp. 71-79
-
-
Praetorius, H.A.1
Spring, K.R.2
-
66
-
-
0037557518
-
Removal of the MDCK cell primary cilium abolishes flow sensing
-
Praetorius, H.A., Spring, K.R., Removal of the MDCK cell primary cilium abolishes flow sensing. J. Membr. Biol. 191 (2003), 69–76.
-
(2003)
J. Membr. Biol.
, vol.191
, pp. 69-76
-
-
Praetorius, H.A.1
Spring, K.R.2
-
67
-
-
0030582668
-
The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I
-
Qian, F., Watnick, T.J., Onuchic, L.F., Germino, G.G., The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I. Cell 87 (1996), 979–987.
-
(1996)
Cell
, vol.87
, pp. 979-987
-
-
Qian, F.1
Watnick, T.J.2
Onuchic, L.F.3
Germino, G.G.4
-
68
-
-
0031105408
-
Cell lines with extended in vitro growth potential from human renal proximal tubule: characterization, response to inducers, and comparison with established cell lines
-
Racusen, L.C., Monteil, C., Sgrignoli, A., Lucskay, M., Marouillat, S., Rhim, J.G., Morin, J.P., Cell lines with extended in vitro growth potential from human renal proximal tubule: characterization, response to inducers, and comparison with established cell lines. J. Lab. Clin. Med. 129 (1997), 318–329.
-
(1997)
J. Lab. Clin. Med.
, vol.129
, pp. 318-329
-
-
Racusen, L.C.1
Monteil, C.2
Sgrignoli, A.3
Lucskay, M.4
Marouillat, S.5
Rhim, J.G.6
Morin, J.P.7
-
69
-
-
84902176106
-
Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia
-
Raghavan, V., Rbaibi, Y., Pastor-Soler, N.M., Carattino, M.D., Weisz, O.A., Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia. Proc. Natl. Acad. Sci. USA 111 (2014), 8506–8511.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 8506-8511
-
-
Raghavan, V.1
Rbaibi, Y.2
Pastor-Soler, N.M.3
Carattino, M.D.4
Weisz, O.A.5
-
70
-
-
85043118735
-
Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia
-
Raghavan, V., Rbaibi, Y., Pastor-Soler, N.M., Carattino, M.D., Weisz, O.A., Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia. Proc. Natl. Acad. Sci. USA, 2016.
-
(2016)
Proc. Natl. Acad. Sci. USA
-
-
Raghavan, V.1
Rbaibi, Y.2
Pastor-Soler, N.M.3
Carattino, M.D.4
Weisz, O.A.5
-
71
-
-
79958067466
-
Impact and frequency of different toxicities throughout the pharmaceutical life cycle
-
Redfern, W.S., Ewart, L., Hammond, T.G., Bialecki, R., Kinter, L., Lindgren, S., Impact and frequency of different toxicities throughout the pharmaceutical life cycle. Toxicologist, 2010, 1081.
-
(2010)
Toxicologist
, pp. 1081
-
-
Redfern, W.S.1
Ewart, L.2
Hammond, T.G.3
Bialecki, R.4
Kinter, L.5
Lindgren, S.6
-
72
-
-
84887223447
-
Principles and Practice of Toxicology in Public Health
-
Jones And Bartlell Publishers Sudbury, Massachusetts
-
Richards, I.S., Principles and Practice of Toxicology in Public Health. 2008, Jones And Bartlell Publishers, Sudbury, Massachusetts.
-
(2008)
-
-
Richards, I.S.1
-
74
-
-
51249105551
-
Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1
-
Sato, T., Masuda, S., Yonezawa, A., Tanihara, Y., Katsura, T., Inui, K., Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1. Biochem. Pharmacol. 76 (2008), 894–903.
-
(2008)
Biochem. Pharmacol.
, vol.76
, pp. 894-903
-
-
Sato, T.1
Masuda, S.2
Yonezawa, A.3
Tanihara, Y.4
Katsura, T.5
Inui, K.6
-
75
-
-
67649696936
-
Apical lumen formation in renal epithelia
-
Schluter, M.A., Margolis, B., Apical lumen formation in renal epithelia. J. Am. Soc. Nephrol. 20 (2009), 1444–1452.
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 1444-1452
-
-
Schluter, M.A.1
Margolis, B.2
-
76
-
-
84921831300
-
Development of a living membrane comprising a functional human renal proximal tubule cell monolayer on polyethersulfone polymeric membrane
-
Schophuizen, C.M., De Napoli, I.E., Jansen, J., Teixeira, S., Wilmer, M.J., Hoenderop, J.G., Van den Heuvel, L.P., Masereeuw, R., Stamatialis, D., Development of a living membrane comprising a functional human renal proximal tubule cell monolayer on polyethersulfone polymeric membrane. Acta Biomater. 14 (2015), 22–32.
-
(2015)
Acta Biomater.
, vol.14
, pp. 22-32
-
-
Schophuizen, C.M.1
De Napoli, I.E.2
Jansen, J.3
Teixeira, S.4
Wilmer, M.J.5
Hoenderop, J.G.6
Van den Heuvel, L.P.7
Masereeuw, R.8
Stamatialis, D.9
-
77
-
-
84890433586
-
Cationic uremic toxins affect human renal proximal tubule cell functioning through interaction with the organic cation transporter
-
Schophuizen, C.M., Wilmer, M.J., Jansen, J., Gustavsson, L., Hilgendorf, C., Hoenderop, J.G., van den Heuvel, L.P., Masereeuw, R., Cationic uremic toxins affect human renal proximal tubule cell functioning through interaction with the organic cation transporter. Pflug. Arch.: Eur. J. Physiol. 465 (2013), 1701–1714.
-
(2013)
Pflug. Arch.: Eur. J. Physiol.
, vol.465
, pp. 1701-1714
-
-
Schophuizen, C.M.1
Wilmer, M.J.2
Jansen, J.3
Gustavsson, L.4
Hilgendorf, C.5
Hoenderop, J.G.6
van den Heuvel, L.P.7
Masereeuw, R.8
-
78
-
-
77956290011
-
A novel, low-volume method for organ culture of embryonic kidneys that allows development of cortico-medullary anatomical organization
-
Sebinger, D.D., Unbekandt, M., Ganeva, V.V., Ofenbauer, A., Werner, C., Davies, J.A., A novel, low-volume method for organ culture of embryonic kidneys that allows development of cortico-medullary anatomical organization. PloS One, 5, 2010, e10550.
-
(2010)
PloS One
, vol.5
, pp. e10550
-
-
Sebinger, D.D.1
Unbekandt, M.2
Ganeva, V.V.3
Ofenbauer, A.4
Werner, C.5
Davies, J.A.6
-
79
-
-
84879589947
-
Increased curvature of hollow fiber membranes could up-regulate differential functions of renal tubular cell layers
-
Shen, C., Meng, Q., Zhang, G., Increased curvature of hollow fiber membranes could up-regulate differential functions of renal tubular cell layers. Biotechnol. Bioeng. 110 (2013), 2173–2183.
-
(2013)
Biotechnol. Bioeng.
, vol.110
, pp. 2173-2183
-
-
Shen, C.1
Meng, Q.2
Zhang, G.3
-
80
-
-
0022457103
-
Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification
-
Shen, D.W., Fojo, A., Chin, J.E., Roninson, I.B., Richert, N., Pastan, I., Gottesman, M.M., Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification. Science 232 (1986), 643–645.
-
(1986)
Science
, vol.232
, pp. 643-645
-
-
Shen, D.W.1
Fojo, A.2
Chin, J.E.3
Roninson, I.B.4
Richert, N.5
Pastan, I.6
Gottesman, M.M.7
-
81
-
-
33645769011
-
The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease
-
Shillingford, J.M., Murcia, N.S., Larson, C.H., Low, S.H., Hedgepeth, R., Brown, N., Flask, C.A., Novick, A.C., Goldfarb, D.A., Kramer-Zucker, A., Walz, G., Piontek, K.B., Germino, G.G., Weimbs, T., The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease. Proc. Natl. Acad. Sci. USA 103 (2006), 5466–5471.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 5466-5471
-
-
Shillingford, J.M.1
Murcia, N.S.2
Larson, C.H.3
Low, S.H.4
Hedgepeth, R.5
Brown, N.6
Flask, C.A.7
Novick, A.C.8
Goldfarb, D.A.9
Kramer-Zucker, A.10
Walz, G.11
Piontek, K.B.12
Germino, G.G.13
Weimbs, T.14
-
82
-
-
84960157420
-
Autosomal dominant polycystic kidney disease
-
Simms, R.J., Autosomal dominant polycystic kidney disease. Br. Med. J., 352, 2016, i679.
-
(2016)
Br. Med. J.
, vol.352
, pp. i679
-
-
Simms, R.J.1
-
83
-
-
84859635020
-
Analysis of transcriptomic and proteomic profiles demonstrates improved Madin-Darby canine kidney cell function in a renal microfluidic biochip
-
Snouber, L.C., Letourneur, F., Chafey, P., Broussard, C., Monge, M., Legallais, C., Leclerc, E., Analysis of transcriptomic and proteomic profiles demonstrates improved Madin-Darby canine kidney cell function in a renal microfluidic biochip. Biotechnol. Prog. 28 (2012), 474–484.
-
(2012)
Biotechnol. Prog.
, vol.28
, pp. 474-484
-
-
Snouber, L.C.1
Letourneur, F.2
Chafey, P.3
Broussard, C.4
Monge, M.5
Legallais, C.6
Leclerc, E.7
-
84
-
-
34447280626
-
Micropatterns of matrigel for three-dimensional epithelial cultures
-
Sodunke, T.R., Turner, K.K., Caldwell, S.A., McBride, K.W., Reginato, M.J., Noh, H.M., Micropatterns of matrigel for three-dimensional epithelial cultures. Biomaterials 28 (2007), 4006–4016.
-
(2007)
Biomaterials
, vol.28
, pp. 4006-4016
-
-
Sodunke, T.R.1
Turner, K.K.2
Caldwell, S.A.3
McBride, K.W.4
Reginato, M.J.5
Noh, H.M.6
-
85
-
-
73949109329
-
Expression and function of p-glycoprotein in normal tissues: effect on pharmacokinetics
-
Staud, F., Ceckova, M., Micuda, S., Pavek, P., Expression and function of p-glycoprotein in normal tissues: effect on pharmacokinetics. Methods Mol. Biol. 596 (2010), 199–222.
-
(2010)
Methods Mol. Biol.
, vol.596
, pp. 199-222
-
-
Staud, F.1
Ceckova, M.2
Micuda, S.3
Pavek, P.4
-
86
-
-
33846246380
-
PDMS absorption of small molecules and consequences in microfluidic applications
-
Toepke, M.W., Beebe, D.J., PDMS absorption of small molecules and consequences in microfluidic applications. Lab Chip 6 (2006), 1484–1486.
-
(2006)
Lab Chip
, vol.6
, pp. 1484-1486
-
-
Toepke, M.W.1
Beebe, D.J.2
-
87
-
-
63849121023
-
Involvement of human multidrug and toxin extrusion 1 in the drug interaction between cimetidine and metformin in renal epithelial cells
-
Tsuda, M., Terada, T., Ueba, M., Sato, T., Masuda, S., Katsura, T., Inui, K., Involvement of human multidrug and toxin extrusion 1 in the drug interaction between cimetidine and metformin in renal epithelial cells. J. Pharmacol. Exp. Ther. 329 (2009), 185–191.
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.329
, pp. 185-191
-
-
Tsuda, M.1
Terada, T.2
Ueba, M.3
Sato, T.4
Masuda, S.5
Katsura, T.6
Inui, K.7
-
88
-
-
84907168761
-
Expression profiles of genes involved in xenobiotic metabolism and disposition in human renal tissues and renal cell models
-
Van der Hauwaert, C., Savary, G., Buob, D., Leroy, X., Aubert, S., Flamand, V., Hennino, M.F., Perrais, M., Lo-Guidice, J.M., Broly, F., Cauffiez, C., Glowacki, F., Expression profiles of genes involved in xenobiotic metabolism and disposition in human renal tissues and renal cell models. Toxicol. Appl. Pharmacol. 279 (2014), 409–418.
-
(2014)
Toxicol. Appl. Pharmacol.
, vol.279
, pp. 409-418
-
-
Van der Hauwaert, C.1
Savary, G.2
Buob, D.3
Leroy, X.4
Aubert, S.5
Flamand, V.6
Hennino, M.F.7
Perrais, M.8
Lo-Guidice, J.M.9
Broly, F.10
Cauffiez, C.11
Glowacki, F.12
-
89
-
-
84934942592
-
Microfluidic 3D cell culture: from tools to tissue models
-
van Duinen, V., Trietsch, S.J., Joore, J., Vulto, P., Hankemeier, T., Microfluidic 3D cell culture: from tools to tissue models. Curr. Opin. Biotechnol. 35 (2015), 118–126.
-
(2015)
Curr. Opin. Biotechnol.
, vol.35
, pp. 118-126
-
-
van Duinen, V.1
Trietsch, S.J.2
Joore, J.3
Vulto, P.4
Hankemeier, T.5
-
90
-
-
73949083886
-
Microfluidic biochip for the perifusion of precision-cut rat liver slices for metabolism and toxicology studies
-
van Midwoud, P.M., Groothuis, G.M., Merema, M.T., Verpoorte, E., Microfluidic biochip for the perifusion of precision-cut rat liver slices for metabolism and toxicology studies. Biotechnol. Bioeng. 105 (2010), 184–194.
-
(2010)
Biotechnol. Bioeng.
, vol.105
, pp. 184-194
-
-
van Midwoud, P.M.1
Groothuis, G.M.2
Merema, M.T.3
Verpoorte, E.4
-
91
-
-
84860439214
-
Comparison of biocompatibility and adsorption properties of different plastics for advanced microfluidic cell and tissue culture models
-
van Midwoud, P.M., Janse, A., Merema, M.T., Groothuis, G.M., Verpoorte, E., Comparison of biocompatibility and adsorption properties of different plastics for advanced microfluidic cell and tissue culture models. Anal. Chem. 84 (2012), 3938–3944.
-
(2012)
Anal. Chem.
, vol.84
, pp. 3938-3944
-
-
van Midwoud, P.M.1
Janse, A.2
Merema, M.T.3
Groothuis, G.M.4
Verpoorte, E.5
-
92
-
-
68549122719
-
Physicochemical determinants of human renal clearance
-
Varma, M.V., Feng, B., Obach, R.S., Troutman, M.D., Chupka, J., Miller, H.R., El-Kattan, A., Physicochemical determinants of human renal clearance. J. Med. Chem. 52 (2009), 4844–4852.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 4844-4852
-
-
Varma, M.V.1
Feng, B.2
Obach, R.S.3
Troutman, M.D.4
Chupka, J.5
Miller, H.R.6
El-Kattan, A.7
-
93
-
-
51349115583
-
Reducing renal uptake of radiolabeled peptides using albumin fragments
-
Vegt, E., van Eerd, J.E., Eek, A., Oyen, W.J., Wetzels, J.F., de Jong, M., Russel, F.G., Masereeuw, R., Gotthardt, M., Boerman, O.C., Reducing renal uptake of radiolabeled peptides using albumin fragments. J. Nucl. Med.: Off. Publ. Soc. Nucl. Med. 49 (2008), 1506–1511.
-
(2008)
J. Nucl. Med.: Off. Publ. Soc. Nucl. Med.
, vol.49
, pp. 1506-1511
-
-
Vegt, E.1
van Eerd, J.E.2
Eek, A.3
Oyen, W.J.4
Wetzels, J.F.5
de Jong, M.6
Russel, F.G.7
Masereeuw, R.8
Gotthardt, M.9
Boerman, O.C.10
-
94
-
-
48449092858
-
Alterations in renal cilium length during transient complete ureteral obstruction in the mouse
-
Wang, L., Weidenfeld, R., Verghese, E., Ricardo, S.D., Deane, J.A., Alterations in renal cilium length during transient complete ureteral obstruction in the mouse. J. Anat. 213 (2008), 79–85.
-
(2008)
J. Anat.
, vol.213
, pp. 79-85
-
-
Wang, L.1
Weidenfeld, R.2
Verghese, E.3
Ricardo, S.D.4
Deane, J.A.5
-
95
-
-
36649014876
-
Apical junctional complexes and cell polarity
-
Wang, Q., Margolis, B., Apical junctional complexes and cell polarity. Kidney Int. 72 (2007), 1448–1458.
-
(2007)
Kidney Int.
, vol.72
, pp. 1448-1458
-
-
Wang, Q.1
Margolis, B.2
-
96
-
-
0036726312
-
beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
-
Weaver, V.M., Lelievre, S., Lakins, J.N., Chrenek, M.A., Jones, J.C., Giancotti, F., Werb, Z., Bissell, M.J., beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell 2 (2002), 205–216.
-
(2002)
Cancer Cell
, vol.2
, pp. 205-216
-
-
Weaver, V.M.1
Lelievre, S.2
Lakins, J.N.3
Chrenek, M.A.4
Jones, J.C.5
Giancotti, F.6
Werb, Z.7
Bissell, M.J.8
-
97
-
-
78349266424
-
The pathogenesis of cystinosis: mechanisms beyond cystine accumulation
-
Wilmer, M.J., Emma, F., Levtchenko, E.N., The pathogenesis of cystinosis: mechanisms beyond cystine accumulation. Am. J. Physiol. Ren. Physiol. 299 (2010), F905–F916.
-
(2010)
Am. J. Physiol. Ren. Physiol.
, vol.299
, pp. F905-F916
-
-
Wilmer, M.J.1
Emma, F.2
Levtchenko, E.N.3
-
98
-
-
79954571291
-
Cysteamine restores glutathione redox status in cultured cystinotic proximal tubular epithelial cells
-
Wilmer, M.J., Kluijtmans, L.A., van der Velden, T.J., Willems, P.H., Scheffer, P.G., Masereeuw, R., Monnens, L.A., van den Heuvel, L.P., Levtchenko, E.N., Cysteamine restores glutathione redox status in cultured cystinotic proximal tubular epithelial cells. Biochim. Biophys. Acta 1812 (2011), 643–651.
-
(2011)
Biochim. Biophys. Acta
, vol.1812
, pp. 643-651
-
-
Wilmer, M.J.1
Kluijtmans, L.A.2
van der Velden, T.J.3
Willems, P.H.4
Scheffer, P.G.5
Masereeuw, R.6
Monnens, L.A.7
van den Heuvel, L.P.8
Levtchenko, E.N.9
-
99
-
-
84960177173
-
Kidney-on-a-chip technology for drug-induced nephrotoxicity screening
-
Wilmer, M.J., Ng, C.P., Lanz, H.L., Vulto, P., Suter-Dick, L., Masereeuw, R., Kidney-on-a-chip technology for drug-induced nephrotoxicity screening. Trends Biotechnol. 34 (2016), 156–170.
-
(2016)
Trends Biotechnol.
, vol.34
, pp. 156-170
-
-
Wilmer, M.J.1
Ng, C.P.2
Lanz, H.L.3
Vulto, P.4
Suter-Dick, L.5
Masereeuw, R.6
-
100
-
-
77949269535
-
Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters
-
Wilmer, M.J., Saleem, M.A., Masereeuw, R., Ni, L., van der Velden, T.J., Russel, F.G., Mathieson, P.W., Monnens, L.A., van den Heuvel, L.P., Levtchenko, E.N., Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters. Cell Tissue Res. 339 (2010), 449–457.
-
(2010)
Cell Tissue Res.
, vol.339
, pp. 449-457
-
-
Wilmer, M.J.1
Saleem, M.A.2
Masereeuw, R.3
Ni, L.4
van der Velden, T.J.5
Russel, F.G.6
Mathieson, P.W.7
Monnens, L.A.8
van den Heuvel, L.P.9
Levtchenko, E.N.10
-
101
-
-
12844272106
-
Beta1-integrin orients epithelial polarity via Rac1 and laminin
-
Yu, W., Datta, A., Leroy, P., O'Brien, L.E., Mak, G., Jou, T.S., Matlin, K.S., Mostov, K.E., Zegers, M.M., Beta1-integrin orients epithelial polarity via Rac1 and laminin. Mol. Biol. Cell 16 (2005), 433–445.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 433-445
-
-
Yu, W.1
Datta, A.2
Leroy, P.3
O'Brien, L.E.4
Mak, G.5
Jou, T.S.6
Matlin, K.S.7
Mostov, K.E.8
Zegers, M.M.9
-
102
-
-
72049119863
-
Towards a human-on-chip: culturing multiple cell types on a chip with compartmentalized microenvironments
-
Zhang, C., Zhao, Z., Abdul Rahim, N.A., van Noort, D., Yu, H., Towards a human-on-chip: culturing multiple cell types on a chip with compartmentalized microenvironments. Lab Chip 9 (2009), 3185–3192.
-
(2009)
Lab Chip
, vol.9
, pp. 3185-3192
-
-
Zhang, C.1
Zhao, Z.2
Abdul Rahim, N.A.3
van Noort, D.4
Yu, H.5
|