Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 17, 2013, Pages 7014-7019

  Gorvin, Caroline M ^a   Wilmer, Martijn J ^b   Piret, Sian E ^a   Harding, Brian ^a   Van Den Heuvel, Lambertus P ^c,d   Wrong, Oliver ^e   Jat, Parmjit S ^f   Lippiat, Jonathan D ^g   Levtchenko, Elena N ^c,d   Thakker, Rajesh V ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF LEUVEN   (Belgium)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

^g UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BAFILOMYCIN A1; CHLORIDE CHANNEL; CHLORIDE CHANNEL 5; MEMBRANE PROTEIN; MEMBRANE PROTEIN EB1; PROTEIN ZO1; TRANSFERRIN; UNCLASSIFIED DRUG;

ACIDIFICATION; ARTICLE; CELL IMMORTALIZATION; CELL POLARITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENT DISEASE; ENDOCYTOSIS; ENDOSOME; EPITHELIUM CELL; GENE MUTATION; HUMAN; HUMAN CELL; KIDNEY EPITHELIUM; KIDNEY PROXIMAL TUBULE; MICROTUBULE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL;

CELL LINE; CHLORIDE CHANNELS; DENT DISEASE; ENDOCYTOSIS; ENDOSOMES; EPITHELIAL CELLS; GREEN FLUORESCENT PROTEINS; HUMANS; HYDROGEN-ION CONCENTRATION; KIDNEY TUBULES, PROXIMAL; MICROSCOPY, CONFOCAL; MUTATION; VESICLE-ASSOCIATED MEMBRANE PROTEIN 2;

EID: 84876855574     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1302063110     Document Type: Article

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