A microfluidic hepatic coculture platform for cell-based drug metabolism studies

Biochemical Pharmacology

Volumn 79, Issue 7, 2010, Pages 1036-1044

  Novik, Eric ^a   Maguire, Timothy J ^a   Chao, Piyun ^a   Cheng, K C ^b   Yarmush, Martin L ^c  

^a Hurel Corporation   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Coculture; Hepatic clearance; Human hepatocyte; Metabolism; Microfluidics

Indexed keywords

ARTICLE; COCULTURE; CONTROLLED STUDY; DRUG METABOLISM; HEPATIC COCULTURE SYSTEM; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CLEARANCE; METABOLITE; MICROFLUIDICS; MOLECULAR DYNAMICS; PRIORITY JOURNAL; TISSUE CULTURE TECHNIQUE; CELL CULTURE; DRUG DEVELOPMENT; LIVER CELL; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY;

CELLS, CULTURED; COCULTURE TECHNIQUES; DRUG DISCOVERY; HEPATOCYTES; HUMANS; METABOLIC CLEARANCE RATE; MICROFLUIDICS;

EID: 77449119885     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.11.010     Document Type: Article

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