Megalin and cubilin in proximal tubule protein reabsorption: From experimental models to human disease

Kidney International

Volumn 89, Issue 1, 2016, Pages 58-67

  Nielsen, Rikke ^a   Christensen, Erik Ilsø ^a   Birn, Henrik ^a,b  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

albuminuria; endocytosis; Fanconi syndrome; proximal tubule

Indexed keywords

ALBUMIN; ALPHA 1 MACROGLOBULIN; APOLIPOPROTEIN A1; BETA 2 GLYCOPROTEIN; BETA 2 MICROGLOBULIN; BONE MORPHOGENETIC PROTEIN RECEPTOR 1; CATHEPSIN B; CATHEPSIN D; COMPLEMENT COMPONENT C1R; COMPLEMENT COMPONENT C1S; CUBILIN; EPIDERMAL GROWTH FACTOR; GLYCOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; MACROGLOBULIN; MEGALIN; NEPHRITOGENIC ANTIGEN; RETINOL; RETINOL BINDING PROTEIN; TRANSCOBALAMIN; UNCLASSIFIED DRUG; VITAMIN D BINDING PROTEIN; CELL SURFACE RECEPTOR; INTRINSIC FACTOR-COBALAMIN RECEPTOR;

ACUTE KIDNEY FAILURE; ALBUMIN BLOOD LEVEL; AMN GENE; AUTOSOMAL RECESSIVE DISORDER; CALCIUM HOMEOSTASIS; CARBOXY TERMINAL SEQUENCE; CHRONIC KIDNEY DISEASE; COHORT ANALYSIS; CUBN GENE; CYANOCOBALAMIN DEFICIENCY; DIABETES MELLITUS; DIETARY INTAKE; DISEASE ASSOCIATION; DISEASE COURSE; DONNAI BARROW SYNDROME; ENDOCYTOSIS; FACIOOCULOACOUSTIC RENAL SYNDROME; GENE; GENOTYPE PHENOTYPE CORRELATION; HUMAN; HYPERTENSION; IMERSLUND GRASBECK DISEASE; IMMUNOGLOBULIN A NEPHROPATHY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY TUBULE ABSORPTION; LRP2 GENE; LYSOSOME; MISSENSE MUTATION; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; PROTEINURIA; REVIEW; URINARY EXCRETION; ANIMAL; CHRONIC KIDNEY FAILURE; DISEASE MODEL; GENETICS; KIDNEY PROXIMAL TUBULE; METABOLISM; PHYSIOLOGY;

ACUTE KIDNEY INJURY; ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; HUMANS; KIDNEY TUBULES, PROXIMAL; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2; RECEPTORS, CELL SURFACE; RENAL INSUFFICIENCY, CHRONIC;

EID: 84973162078     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2015.11.007     Document Type: Review

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