Fluorescence-Based Transport Assays Revisited in a Human Renal Proximal Tubule Cell Line

Molecular Pharmaceutics

Volumn 13, Issue 3, 2016, Pages 933-944

  Caetano Pinto, Pedro ^a,b   Janssen, Manoe J ^a,b   Gijzen, Linda ^a   Verscheijden, Laurens ^a   Wilmer, Martijn J G ^a   Masereeuw, Rosalinde ^a,b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

ABC membrane transporters; advanced in vitro models; fluorescence functional assays; human proximal tubule cells; receptor mediated endocytosis

Indexed keywords

1,2,3,4,6,7,12,12A OCTAHYDRO 6 ISOBUTYL 9 METHOXY 1,4 DIOXOPYRAZINO[1',2':1,6]PYRIDO[3,4 B]INDOLE 3 PROPANOIC ACID TERT BUTYL ESTER; BREAST CANCER RESISTANCE PROTEIN; CHLOROMETHYLFLUORESCEIN DIACETATE; FLUORESCEIN DIACETATE; FLUORESCENT DYE; HOE 33342; MEGALIN; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 4; UNCLASSIFIED DRUG; VALSPODAR; VERLUKAST; ABCC4 PROTEIN, HUMAN; ABCG2 PROTEIN, HUMAN; TUMOR PROTEIN;

ANIMAL CELL; ARTICLE; CALCEIN-AM ASSAY; CONDITIONALLY IMMORTALIZED PROXIMAL TUBULE EPITHELIAL CELL LINE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOCYTOSIS; FLUORESCENCE ANALYSIS; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMORTALIZED CELL LINE; KIDNEY TUBULE ABSORPTION; MDCK CELL LINE; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; TRANSPORT ASSAY; ANIMAL; CELL CULTURE; CYTOLOGY; DOG; FLUORESCENCE; KIDNEY PROXIMAL TUBULE; METABOLISM; PHYSIOLOGY;

ANIMALS; ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY G, MEMBER 2; CELLS, CULTURED; DOGS; ENDOCYTOSIS; FLUORESCENCE; HUMANS; KIDNEY TUBULES, PROXIMAL; MADIN DARBY CANINE KIDNEY CELLS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; P-GLYCOPROTEINS;

EID: 84960120449     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.5b00821     Document Type: Article

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