NAMPT-Mediated NAD+ Biosynthesis Is Essential for Vision In Mice

Cell Reports

Volumn 17, Issue 1, 2016, Pages 69-85

  Lin, Jonathan B ^a   Kubota, Shunsuke ^a   Ban, Norimitsu ^a   Yoshida, Mitsukuni ^a   Santeford, Andrea ^a   Sene, Abdoulaye ^a   Nakamura, Rei ^a   Zapata, Nicole ^a   Kubota, Miyuki ^a   Tsubota, Kazuo ^b   Yoshino, Jun ^a   Imai, Shin ichiro ^a   Apte, Rajendra S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

metabolism; mitochondria; NAD+; neurodegeneration; photoreceptor; retina; sirtuins

Indexed keywords

ADENOSINE TRIPHOSPHATE; ISOCITRATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE NUCLEOTIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; SIRTUIN 3; SIRTUIN 5; CYTOKINE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE, MOUSE; SIRT3 PROTEIN, MOUSE; SIRT5 PROTEIN, MOUSE; SIRTUIN; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOSYNTHESIS; BLINDNESS; CELL SURVIVAL; CONTROLLED STUDY; GENE; GENE DELETION; HOMEOSTASIS; LIGHT; METABOLIC STRESS; MOUSE; MOUSE MODEL; NAMPT GENE; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; RETINA CONE; RETINA DEGENERATION; RETINA ROD; VISION; ANIMAL; C57BL MOUSE; CELL DEATH; CHEMICALLY INDUCED; DEFICIENCY; DIABETIC RETINOPATHY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOCHONDRION; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; CELL DEATH; CYTOKINES; DIABETIC RETINOPATHY; GENE EXPRESSION REGULATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; NAD; NICOTINAMIDE MONONUCLEOTIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; RETINAL DEGENERATION; RETINAL ROD PHOTORECEPTOR CELLS; SIGNAL TRANSDUCTION; SIRTUIN 3; SIRTUINS; STREPTOZOCIN; VISION, OCULAR;

EID: 84989850905     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.08.073     Document Type: Article

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