The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration

Journal of Neuroscience

Volumn 21, Issue 1, 2001, Pages 53-58

  Wenzel, Andreas ^a   Remé, Charlotte E ^a   Williams, Theodore P ^b   Hafezi, Farhad ^a   Grimm, Christian ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Light damage; Photoreceptor; Pigment epithelium; Retinal degeneration; Rhodopsin; RPE65

Indexed keywords

LEUCINE; METHIONINE; PROTEIN RPE65; RHODOPSIN; UNCLASSIFIED DRUG; VISUAL PIGMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DARK ADAPTATION; GENETIC RESISTANCE; GENETIC VARIABILITY; KINETICS; LIGHT ABSORPTION; LIGHT DAMAGE; LIGHT EXPOSURE; MOUSE; MOUSE STRAIN; NONHUMAN; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN METABOLISM; REGENERATION; RETINA DEGENERATION; RETINA MACULA AGE RELATED DEGENERATION; TRANSCRIPTION REGULATION;

EID: 0035144779     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-01-00053.2001     Document Type: Article

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