-
1
-
-
28044471827
-
Acetylation and deacetylation of non-histone proteins
-
Glozak MA, Sengupta N, Zhang X, Seto E (2005) Acetylation and deacetylation of non-histone proteins. Gene 363:15-23.
-
(2005)
Gene
, vol.363
, pp. 15-23
-
-
Glozak, M.A.1
Sengupta, N.2
Zhang, X.3
Seto, E.4
-
2
-
-
33746992118
-
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey
-
Kim SC, et al. (2006) Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. Mol Cell 23(4):607-618.
-
(2006)
Mol Cell
, vol.23
, Issue.4
, pp. 607-618
-
-
Kim, S.C.1
-
3
-
-
68949212379
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions
-
Choudhary C, et al. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325(5942):834-840.
-
(2009)
Science
, vol.325
, Issue.5942
, pp. 834-840
-
-
Choudhary, C.1
-
4
-
-
0037972522
-
Mitochondrial respiratory-chain diseases
-
DiMauro S, Schon EA (2003) Mitochondrial respiratory-chain diseases. N Engl J Med 348(26):2656-2668.
-
(2003)
N Engl J Med
, vol.348
, Issue.26
, pp. 2656-2668
-
-
Dimauro, S.1
Schon, E.A.2
-
5
-
-
25444474703
-
Mitochondria take center stage in aging and neurodegeneration
-
Beal MF (2005) Mitochondria take center stage in aging and neurodegeneration. Ann Neurol 58(4):495-505.
-
(2005)
Ann Neurol
, vol.58
, Issue.4
, pp. 495-505
-
-
Beal, M.F.1
-
6
-
-
38649123072
-
Conserved metabolic regulatory functions of sirtuins
-
Schwer B, Verdin E (2008) Conserved metabolic regulatory functions of sirtuins. Cell Metab 7(2):104-112.
-
(2008)
Cell Metab
, vol.7
, Issue.2
, pp. 104-112
-
-
Schwer, B.1
Verdin, E.2
-
7
-
-
0037135972
-
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine di-nucleotide-dependent deacetylase
-
Schwer B, North BJ, Frye RA, Ott M, Verdin E (2002) The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine di-nucleotide-dependent deacetylase. J Cell Biol 158(4):647-657.
-
(2002)
J Cell Biol
, vol.158
, Issue.4
, pp. 647-657
-
-
Schwer, B.1
North, B.J.2
Frye, R.A.3
Ott, M.4
Verdin, E.5
-
8
-
-
26244436281
-
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
-
Michishita E, Park JY, Burneskis JM, Barrett JC, Horikawa I (2005) Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 16(10):4623-4635.
-
(2005)
Mol Biol Cell
, vol.16
, Issue.10
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
Barrett, J.C.4
Horikawa, I.5
-
9
-
-
37549002891
-
Mammalian Sir2 homolog SIRT3 regulates global mito-chondrial lysine acetylation
-
Lombard DB, et al. (2007) Mammalian Sir2 homolog SIRT3 regulates global mito-chondrial lysine acetylation. Mol Cell Biol 27(24):8807-8814.
-
(2007)
Mol Cell Biol
, vol.27
, Issue.24
, pp. 8807-8814
-
-
Lombard, D.B.1
-
10
-
-
81055122671
-
Sirt5 is a NAD-dependent protein lysine demalonylase and de-succinylase
-
Du J, et al. (2011) Sirt5 is a NAD-dependent protein lysine demalonylase and de-succinylase. Science 334(6057):806-809.
-
(2011)
Science
, vol.334
, Issue.6057
, pp. 806-809
-
-
Du, J.1
-
11
-
-
83055173304
-
The first identification of lysine malonylation substrates and its regulatory enzyme
-
Peng C, et al. (2011) The first identification of lysine malonylation substrates and its regulatory enzyme. Mol Cell Proteomics 10(12):M111012658.
-
(2011)
Mol Cell Proteomics
, vol.10
, Issue.12
-
-
Peng, C.1
-
12
-
-
33748316536
-
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells
-
Haigis MC, et al. (2006) SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell 126(5):941-954.
-
(2006)
Cell
, vol.126
, Issue.5
, pp. 941-954
-
-
Haigis, M.C.1
-
13
-
-
73949123433
-
Calorie restriction alters mitochondrial protein acetylation
-
Schwer B, et al. (2009) Calorie restriction alters mitochondrial protein acetylation. Aging Cell 8(5):604-606.
-
(2009)
Aging Cell
, vol.8
, Issue.5
, pp. 604-606
-
-
Schwer, B.1
-
14
-
-
77950806433
-
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
-
Hirschey MD, et al. (2010) SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature 464(7285):121-125.
-
(2010)
Nature
, vol.464
, Issue.7285
, pp. 121-125
-
-
Hirschey, M.D.1
-
15
-
-
80052291180
-
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
-
Jing E, et al. (2011) Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. Proc Natl Acad Sci USA 108(35):14608-14613.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.35
, pp. 14608-14613
-
-
Jing, E.1
-
16
-
-
75349111140
-
Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria
-
Cimen H, et al. (2010) Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria. Biochemistry 49(2):304-311.
-
(2010)
Biochemistry
, vol.49
, Issue.2
, pp. 304-311
-
-
Cimen, H.1
-
17
-
-
80051716282
-
Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity
-
Finley LW, et al. (2011) Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity. PLoS ONE 6(8):e23295.
-
(2011)
PLoS ONE
, vol.6
, Issue.8
-
-
Finley, L.W.1
-
18
-
-
55749084738
-
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
-
Ahn BH, et al. (2008) A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc Natl Acad Sci USA 105(38):14447-14452.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.38
, pp. 14447-14452
-
-
Ahn, B.H.1
-
19
-
-
78649509214
-
SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production
-
Shimazu T, et al. (2010) SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metab 12(6):654-661.
-
(2010)
Cell Metab
, vol.12
, Issue.6
, pp. 654-661
-
-
Shimazu, T.1
-
20
-
-
79957979314
-
Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS
-
Chen Y, et al. (2011) Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS. EMBO Rep 12(6):534-541.
-
(2011)
EMBO Rep
, vol.12
, Issue.6
, pp. 534-541
-
-
Chen, Y.1
-
21
-
-
78649521247
-
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
-
Qiu X, Brown K, Hirschey MD, Verdin E, Chen D (2010) Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab 12(6):662-667.
-
(2010)
Cell Metab
, vol.12
, Issue.6
, pp. 662-667
-
-
Qiu, X.1
Brown, K.2
Hirschey, M.D.3
Verdin, E.4
Chen, D.5
-
22
-
-
78650248160
-
Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress
-
Tao R, et al. (2010) Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress. Mol Cell 40(6):893-904.
-
(2010)
Mol Cell
, vol.40
, Issue.6
, pp. 893-904
-
-
Tao, R.1
-
23
-
-
79959819034
-
SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production
-
Bell EL, Emerling BM, Ricoult SJ, Guarente L (2011) SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production. Oncogene 30(26):2986-2996.
-
(2011)
Oncogene
, vol.30
, Issue.26
, pp. 2986-2996
-
-
Bell, E.L.1
Emerling, B.M.2
Ricoult, S.J.3
Guarente, L.4
-
24
-
-
79952501323
-
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
-
Finley LW, et al. (2011) SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization. Cancer Cell 19(3):416-428.
-
(2011)
Cancer Cell
, vol.19
, Issue.3
, pp. 416-428
-
-
Finley, L.W.1
-
25
-
-
78651468722
-
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
-
Someya S, et al. (2010) Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell 143(5):802-812.
-
(2010)
Cell
, vol.143
, Issue.5
, pp. 802-812
-
-
Someya, S.1
-
26
-
-
84861178173
-
Platform-independent and label-free quantitation of pro-teomic data using MS1 extracted ion chromatograms in skyline: Application to protein acetylation and phosphorylation
-
Schilling B, et al. (2012) Platform-independent and label-free quantitation of pro-teomic data using MS1 extracted ion chromatograms in skyline: Application to protein acetylation and phosphorylation. Mol Cell Proteomics 11(5):202-214.
-
(2012)
Mol Cell Proteomics
, vol.11
, Issue.5
, pp. 202-214
-
-
Schilling, B.1
-
27
-
-
79955809067
-
Methods for peptide and protein quantitation by liquid chro-matography-multiple reaction monitoring mass spectrometry
-
Zhang H, et al. (2011) Methods for peptide and protein quantitation by liquid chro-matography-multiple reaction monitoring mass spectrometry. Mol Cell Proteomics 10(6):M110006593.
-
(2011)
Mol Cell Proteomics
, vol.10
, Issue.6
-
-
Zhang, H.1
-
28
-
-
78651275182
-
Reactome: A database of reactions, pathways and biological processes
-
Database issue
-
Croft D, et al. (2011) Reactome: a database of reactions, pathways and biological processes. Nucleic Acids Res 39(Database issue):D691-D697.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Croft, D.1
-
29
-
-
0037795741
-
Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS
-
Gerber SA, Rush J, Stemman O, Kirschner MW, Gygi SP (2003) Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS. Proc Natl Acad Sci USA 100(12):6940-6945.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.12
, pp. 6940-6945
-
-
Gerber, S.A.1
Rush, J.2
Stemman, O.3
Kirschner, M.W.4
Gygi, S.P.5
-
30
-
-
78651468707
-
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction
-
Hallows WC, et al. (2011) Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol Cell 41(2):139-149.
-
(2011)
Mol Cell
, vol.41
, Issue.2
, pp. 139-149
-
-
Hallows, W.C.1
-
31
-
-
67649395959
-
Lysine 88 acetylation negatively regulates ornithine carbamoyl- transferase activity in response to nutrient signals
-
Yu W, et al. (2009) Lysine 88 acetylation negatively regulates ornithine carbamoyl-transferase activity in response to nutrient signals. J Biol Chem 284(20):13669-13675.
-
(2009)
J Biol Chem
, vol.284
, Issue.20
, pp. 13669-13675
-
-
Yu, W.1
-
32
-
-
0034843597
-
AL2CO: Calculation of positional conservation in a protein sequence alignment
-
Pei J, Grishin NV (2001) AL2CO: Calculation of positional conservation in a protein sequence alignment. Bioinformatics 17(8):700-712.
-
(2001)
Bioinformatics
, vol.17
, Issue.8
, pp. 700-712
-
-
Pei, J.1
Grishin, N.V.2
-
33
-
-
70350732744
-
Improved visualization of protein consensus sequences by iceLogo
-
Colaert N, Helsens K, Martens L, Vandekerckhove J, Gevaert K (2009) Improved visualization of protein consensus sequences by iceLogo. Nat Methods 6(11):786-787.
-
(2009)
Nat Methods
, vol.6
, Issue.11
, pp. 786-787
-
-
Colaert, N.1
Helsens, K.2
Martens, L.3
Vandekerckhove, J.4
Gevaert, K.5
-
34
-
-
84865726581
-
Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns
-
Lundby A, et al. (2012) Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Cell Rep 2(2):419-431.
-
(2012)
Cell Rep
, vol.2
, Issue.2
, pp. 419-431
-
-
Lundby, A.1
-
35
-
-
0034671429
-
Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of [alpha]-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress
-
Tretter L, Adam-Vizi V (2000) Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of [alpha]-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress. J Neurosci 20(24):8972-8979.
-
(2000)
J Neurosci
, vol.20
, Issue.24
, pp. 8972-8979
-
-
Tretter, L.1
Adam-Vizi, V.2
-
36
-
-
23244435445
-
The alpha-ketoglutarate-dehydrogenase complex: A mediator between mitochondria and oxidative stress in neurodegeneration
-
Gibson GE, Blass JP, Beal MF, Bunik V (2005) The alpha-ketoglutarate- dehydrogenase complex: A mediator between mitochondria and oxidative stress in neurodegeneration. Mol Neurobiol 31(1-3):43-63.
-
(2005)
Mol Neurobiol
, vol.31
, Issue.1-3
, pp. 43-63
-
-
Gibson, G.E.1
Blass, J.P.2
Beal, M.F.3
Bunik, V.4
-
37
-
-
0034987233
-
Lack of mitochondrial trifunctional protein in mice causes neonatal hypoglycemia and sudden death
-
Ibdah JA, et al. (2001) Lack of mitochondrial trifunctional protein in mice causes neonatal hypoglycemia and sudden death. J Clin Invest 107(11):1403-1409.
-
(2001)
J Clin Invest
, vol.107
, Issue.11
, pp. 1403-1409
-
-
Ibdah, J.A.1
-
38
-
-
82455212901
-
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome
-
Hirschey MD, et al. (2011) SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Mol Cell 44(2):177-190.
-
(2011)
Mol Cell
, vol.44
, Issue.2
, pp. 177-190
-
-
Hirschey, M.D.1
-
39
-
-
0037402422
-
Mass spectrometric quantification of acetylation at specific lysines within the amino-terminal tail of histone H4
-
Smith CM, et al. (2003) Mass spectrometric quantification of acetylation at specific lysines within the amino-terminal tail of histone H4. Anal Biochem 316(1):23-33.
-
(2003)
Anal Biochem
, vol.316
, Issue.1
, pp. 23-33
-
-
Smith, C.M.1
-
40
-
-
35848936709
-
Cross-regulation of histone modifications
-
Latham JA, Dent SY (2007) Cross-regulation of histone modifications. Nat Struct Mol Biol 14(11):1017-1024.
-
(2007)
Nat Struct Mol Biol
, vol.14
, Issue.11
, pp. 1017-1024
-
-
Latham, J.A.1
Dent, S.Y.2
|