메뉴 건너뛰기




Volumn 12, Issue 10, 2016, Pages 1157-1168

Progress and prospects in pharmacogenetics of antidepressant drugs

Author keywords

antidepressant; gene; GWAS; Major depression; pharmacogenomics; polymorphism; tailored treatment

Indexed keywords

ANTIDEPRESSANT AGENT;

EID: 84987811430     PISSN: 17425255     EISSN: 17447607     Source Type: Journal    
DOI: 10.1080/17425255.2016.1202237     Document Type: Review
Times cited : (33)

References (116)
  • 1
    • 2542498720 scopus 로고    scopus 로고
    • Prevalence, severity, and unmet need for treatment of mental disorders in the world health organization world mental health surveys
    • K.Demyttenaere, R.Bruffaerts, J.Posada-Villa, et al. Prevalence, severity, and unmet need for treatment of mental disorders in the world health organization world mental health surveys. JAMA. 2004;291:2581–2590.
    • (2004) JAMA , vol.291 , pp. 2581-2590
    • Demyttenaere, K.1    Bruffaerts, R.2    Posada-Villa, J.3
  • 2
    • 84940447040 scopus 로고    scopus 로고
    • Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the global burden of disease study 2013
    • Global Burden of Disease Study Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013:a systematic analysis for the global burden of disease study 2013. Lancet. 2015;386:743–800.
    • (2015) Lancet , vol.386 , pp. 743-800
  • 3
    • 84857099651 scopus 로고    scopus 로고
    • Putting the efficacy of psychiatric and general medicine medication into perspective: review of meta-analyses
    • S.Leucht, S.Hierl, W.Kissling, et al. Putting the efficacy of psychiatric and general medicine medication into perspective:review of meta-analyses. Br J Psychiatry. 2012;200:97–106.
    • (2012) Br J Psychiatry , vol.200 , pp. 97-106
    • Leucht, S.1    Hierl, S.2    Kissling, W.3
  • 4
    • 30044433660 scopus 로고    scopus 로고
    • Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice
    • M.H.Trivedi, A.J.Rush, S.R.Wisniewski, et al. Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D:implications for clinical practice. Am J Psychiatry. 2006;163:28–40.
    • (2006) Am J Psychiatry , vol.163 , pp. 28-40
    • Trivedi, M.H.1    Rush, A.J.2    Wisniewski, S.R.3
  • 5
    • 79960583176 scopus 로고    scopus 로고
    • Switching antidepressant class does not improve response or remission in treatment-resistant depression
    • D.Souery, A.Serretti, R.Calati, et al. Switching antidepressant class does not improve response or remission in treatment-resistant depression. J Clin Psychopharmacol. 2011;31:512–516.
    • (2011) J Clin Psychopharmacol , vol.31 , pp. 512-516
    • Souery, D.1    Serretti, A.2    Calati, R.3
  • 6
    • 0028145779 scopus 로고
    • Pharmacogenetic response to antidepressants in a multicase family with affective disorder
    • R.L.O’Reilly, L.Bogue, S.M.Singh Pharmacogenetic response to antidepressants in a multicase family with affective disorder. Biol Psychiatry. 1994;36:467–471.
    • (1994) Biol Psychiatry , vol.36 , pp. 467-471
    • O’Reilly, R.L.1    Bogue, L.2    Singh, S.M.3
  • 7
    • 0001459580 scopus 로고
    • Differentiation of two genetically specific types of depression by the response to anti-depressants
    • C.M.Pare, L.Rees, M.J.Sainsbury. Differentiation of two genetically specific types of depression by the response to anti-depressants. Lancet. 1962;2:1340–1343.
    • (1962) Lancet , vol.2 , pp. 1340-1343
    • Pare, C.M.1    Rees, L.2    Sainsbury, M.J.3
  • 8
    • 0032167874 scopus 로고    scopus 로고
    • Familial concordance of fluvoxamine response as a tool for differentiating mood disorder pedigrees
    • L.Franchini, A.Serretti, M.Gasperini, et al. Familial concordance of fluvoxamine response as a tool for differentiating mood disorder pedigrees. J Psychiatr Res. 1998;32:255–259.
    • (1998) J Psychiatr Res , vol.32 , pp. 255-259
    • Franchini, L.1    Serretti, A.2    Gasperini, M.3
  • 9
    • 84881546858 scopus 로고    scopus 로고
    • Pharmacogenetics of antidepressant drugs: an update after almost 20 years of research
    • C.Fabbri, G.Di Girolamo, A.Serretti. Pharmacogenetics of antidepressant drugs:an update after almost 20 years of research. Am J Med Genet B Neuropsychiatr Genet. 2013;162B:487–520.
    • (2013) Am J Med Genet B Neuropsychiatr Genet , vol.162B , pp. 487-520
    • Fabbri, C.1    Di Girolamo, G.2    Serretti, A.3
  • 10
    • 79952012111 scopus 로고    scopus 로고
    • Looking on the bright side of serotonin transporter gene variation
    • J.R.Homberg, K.-P.Lesch. Looking on the bright side of serotonin transporter gene variation. Biol Psychiatry. 2011;69:513–519.
    • (2011) Biol Psychiatry , vol.69 , pp. 513-519
    • Homberg, J.R.1    Lesch, K.-P.2
  • 11
    • 84857236103 scopus 로고    scopus 로고
    • Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy
    • S.Porcelli, C.Fabbri, A.Serretti. Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy. Eur Neuropsychopharmacol. 2012;22:239–258.
    • (2012) Eur Neuropsychopharmacol , vol.22 , pp. 239-258
    • Porcelli, S.1    Fabbri, C.2    Serretti, A.3
  • 12
    • 84929321139 scopus 로고    scopus 로고
    • Allelic variation in 5-HTTLPR and the effects of citalopram on the emotional neural network
    • Y.Ma, B.Li, C.Wang, et al. Allelic variation in 5-HTTLPR and the effects of citalopram on the emotional neural network. Br J Psychiatry. 2015;206:385–392.
    • (2015) Br J Psychiatry , vol.206 , pp. 385-392
    • Ma, Y.1    Li, B.2    Wang, C.3
  • 13
    • 84927972867 scopus 로고    scopus 로고
    • SLC6A4 polymorphisms and age of onset in late-life depression on treatment outcomes with citalopram: a sequenced treatment alternatives to relieve depression (STAR*D) report
    • P.R.Shiroma, M.S.Drews, J.R.Geske, et al. SLC6A4 polymorphisms and age of onset in late-life depression on treatment outcomes with citalopram:a sequenced treatment alternatives to relieve depression (STAR*D) report. Am J Geriatr Psychiatry. 2014;22:1140–1148.
    • (2014) Am J Geriatr Psychiatry , vol.22 , pp. 1140-1148
    • Shiroma, P.R.1    Drews, M.S.2    Geske, J.R.3
  • 14
    • 66049122575 scopus 로고    scopus 로고
    • Frontal-limbic white matter pathway associations with the serotonin transporter gene promoter region (5-HTTLPR) polymorphism
    • J.Pacheco, C.G.Beevers, C.Benavides, et al. Frontal-limbic white matter pathway associations with the serotonin transporter gene promoter region (5-HTTLPR) polymorphism. J Neurosci. 2009;29:6229–6233.
    • (2009) J Neurosci , vol.29 , pp. 6229-6233
    • Pacheco, J.1    Beevers, C.G.2    Benavides, C.3
  • 15
    • 84938751655 scopus 로고    scopus 로고
    • Successful antidepressant chronotherapeutics enhance fronto-limbic neural responses and connectivity in bipolar depression
    • B.Vai, S.Poletti, D.Radaelli, et al. Successful antidepressant chronotherapeutics enhance fronto-limbic neural responses and connectivity in bipolar depression. Psychiatry Res. 2015;233:243–253.
    • (2015) Psychiatry Res , vol.233 , pp. 243-253
    • Vai, B.1    Poletti, S.2    Radaelli, D.3
  • 16
    • 84955110711 scopus 로고    scopus 로고
    • Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: a translational approach
    • G.Qesseveur, A.C.Petit, H.T.Nguyen, et al. Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs:a translational approach. Neuropharmacology. 2016;105:142–153.
    • (2016) Neuropharmacology , vol.105 , pp. 142-153
    • Qesseveur, G.1    Petit, A.C.2    Nguyen, H.T.3
  • 17
    • 84907321738 scopus 로고    scopus 로고
    • Influence of 5-HTR2A genetic polymorphisms on the efficacy of antidepressants in the treatment of major depressive disorder: a meta-analysis
    • J.-Y.Lin, M.-Y.Jiang, Z.-M.Kan, et al. Influence of 5-HTR2A genetic polymorphisms on the efficacy of antidepressants in the treatment of major depressive disorder:a meta-analysis. J Affect Disord. 2014;168:430–438.
    • (2014) J Affect Disord , vol.168 , pp. 430-438
    • Lin, J.-Y.1    Jiang, M.-Y.2    Kan, Z.-M.3
  • 18
    • 84927176860 scopus 로고    scopus 로고
    • PPP3CC gene: a putative modulator of antidepressant response through the B-cell receptor signaling pathway
    • C.Fabbri, A.Marsano, D.Albani, et al. PPP3CC gene:a putative modulator of antidepressant response through the B-cell receptor signaling pathway. Pharmacogenomics J. 2014;14:463–472.
    • (2014) Pharmacogenomics J , vol.14 , pp. 463-472
    • Fabbri, C.1    Marsano, A.2    Albani, D.3
  • 19
    • 77957130434 scopus 로고    scopus 로고
    • Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [11C]DASB
    • G.Laje, D.M.Cannon, A.S.Allen, et al. Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [11C]DASB. Int J Neuropsychopharmacol. 2010;13:715–724.
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 715-724
    • Laje, G.1    Cannon, D.M.2    Allen, A.S.3
  • 20
    • 0037244704 scopus 로고    scopus 로고
    • Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression: a potential marker for glucocorticoid sensitivity, potency, and bioavailability
    • H.Vermeer, B.I.Hendriks-Stegeman, B.van der Burg, et al. Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression:a potential marker for glucocorticoid sensitivity, potency, and bioavailability. J Clin Endocrinol Metab. 2003;88:277–284.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 277-284
    • Vermeer, H.1    Hendriks-Stegeman, B.I.2    van der Burg, B.3
  • 21
    • 84873743622 scopus 로고    scopus 로고
    • Glucocorticoid receptor and FKBP5 expression is altered following exposure to chronic stress: modulation by antidepressant treatment
    • G.Guidotti, F.Calabrese, C.Anacker, et al. Glucocorticoid receptor and FKBP5 expression is altered following exposure to chronic stress:modulation by antidepressant treatment. Neuropsychopharmacology. 2013;38:616–627.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 616-627
    • Guidotti, G.1    Calabrese, F.2    Anacker, C.3
  • 22
    • 84872500205 scopus 로고    scopus 로고
    • Candidate genes expression profile associated with antidepressants response in the GENDEP study: differentiating between baseline ‘predictors’ and longitudinal ‘targets’
    • A.Cattaneo, M.Gennarelli, R.Uher, et al. Candidate genes expression profile associated with antidepressants response in the GENDEP study:differentiating between baseline ‘predictors’ and longitudinal ‘targets’. Neuropsychopharmacology. 2013;38:377–385.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 377-385
    • Cattaneo, A.1    Gennarelli, M.2    Uher, R.3
  • 23
    • 9644252785 scopus 로고    scopus 로고
    • Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment
    • E.B.Binder, D.Salyakina, P.Lichtner, et al. Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nat Genet. 2004;36:1319–1325.
    • (2004) Nat Genet , vol.36 , pp. 1319-1325
    • Binder, E.B.1    Salyakina, D.2    Lichtner, P.3
  • 24
    • 84879472437 scopus 로고    scopus 로고
    • Pharmacogenetics in major depression: a comprehensive meta-analysis
    • T.Niitsu, C.Fabbri, F.Bentini, et al. Pharmacogenetics in major depression:a comprehensive meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry. 2013;45:183–194.•• Recent and comprehensive meta-analysis of the main polymorphisms implicated in antidepressant response.
    • (2013) Prog Neuropsychopharmacol Biol Psychiatry , vol.45 , pp. 183-194
    • Niitsu, T.1    Fabbri, C.2    Bentini, F.3
  • 25
    • 0037505703 scopus 로고    scopus 로고
    • A splice variant of the G protein beta 3-subunit implicated in disease states does not modulate ion channels
    • V.Ruiz-Velasco, S.R.Ikeda. A splice variant of the G protein beta 3-subunit implicated in disease states does not modulate ion channels. Physiol Genom. 2003;13:85–95.
    • (2003) Physiol Genom , vol.13 , pp. 85-95
    • Ruiz-Velasco, V.1    Ikeda, S.R.2
  • 26
    • 84908430613 scopus 로고    scopus 로고
    • Influence of GNB3 C825T polymorphism on the efficacy of antidepressants in the treatment of major depressive disorder: a meta-analysis
    • Q.Hu, S.Y.Zhang, F.Liu, et al. Influence of GNB3 C825T polymorphism on the efficacy of antidepressants in the treatment of major depressive disorder:a meta-analysis. J Affect Disord. 2014;172C:103–109.
    • (2014) J Affect Disord , vol.172C , pp. 103-109
    • Hu, Q.1    Zhang, S.Y.2    Liu, F.3
  • 27
    • 84948458945 scopus 로고    scopus 로고
    • Common polymorphisms in the age of research domain criteria (RDoC): integration and translation
    • C.E.Glatt, F.S.Lee. Common polymorphisms in the age of research domain criteria (RDoC):integration and translation. Biol Psychiatry. 2016;79:25–31.
    • (2016) Biol Psychiatry , vol.79 , pp. 25-31
    • Glatt, C.E.1    Lee, F.S.2
  • 28
    • 33748373991 scopus 로고    scopus 로고
    • Transgenic brain-derived neurotrophic factor expression causes both anxiogenic and antidepressant effects
    • A.Govindarajan, B.S.Rao, D.Nair, et al. Transgenic brain-derived neurotrophic factor expression causes both anxiogenic and antidepressant effects. Proc Natl Acad Sci U S A. 2006;103:13208–13213.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 13208-13213
    • Govindarajan, A.1    Rao, B.S.2    Nair, D.3
  • 29
    • 84873348443 scopus 로고    scopus 로고
    • Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies
    • GENDEP Investigators, MARS Investigators, STAR*D Investigators. Common genetic variation and antidepressant efficacy in major depressive disorder:a meta-analysis of three genome-wide pharmacogenetic studies. Am J Psychiatry. 2013;170:207–217.•• Largest available meta-analysis of genome-wide association studies investigating antidepressant response.
    • (2013) Am J Psychiatry , vol.170 , pp. 207-217
  • 30
    • 84987822547 scopus 로고    scopus 로고
    • Available from:
    • Ricopili, a tool for visualizing regions of interest in selected GWAS data sets. Institute B. 2011. Available from: http://www.broadinstitute.org/mpg/ricopili/.• Tool for visualising genetic findings from the largest meta-analysis of genome-wide association studies investigating antidepressant response.
    • (2011) Institute B
  • 31
    • 0344110152 scopus 로고    scopus 로고
    • Pharmacokinetics of selective serotonin reuptake inhibitors
    • C.Hiemke, S.Härtter. Pharmacokinetics of selective serotonin reuptake inhibitors. Pharmacol Ther. 2000;85:11–28.
    • (2000) Pharmacol Ther , vol.85 , pp. 11-28
    • Hiemke, C.1    Härtter, S.2
  • 32
    • 0036219021 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors and cytochrome P-450 mediated drug-drug interactions: an update
    • A.Hemeryck, F.M.Belpaire. Selective serotonin reuptake inhibitors and cytochrome P-450 mediated drug-drug interactions:an update. Curr Drug Metab. 2002;3:13–37.
    • (2002) Curr Drug Metab , vol.3 , pp. 13-37
    • Hemeryck, A.1    Belpaire, F.M.2
  • 33
    • 0141593543 scopus 로고    scopus 로고
    • Metabolic drug interactions with new psychotropic agents
    • E.Spina, M.G.Scordo, C.D’Arrigo. Metabolic drug interactions with new psychotropic agents. Fundam Clin Pharmacol. 2003;17:517–538.
    • (2003) Fundam Clin Pharmacol , vol.17 , pp. 517-538
    • Spina, E.1    Scordo, M.G.2    D’Arrigo, C.3
  • 34
    • 0030222251 scopus 로고    scopus 로고
    • Cerebral metabolism of imipramine and a purified flavin-containing monooxygenase from human brain
    • S.V.Bhagwat, S.Bhamre, M.R.Boyd, et al. Cerebral metabolism of imipramine and a purified flavin-containing monooxygenase from human brain. Neuropsychopharmacology. 1996;15:133–142.
    • (1996) Neuropsychopharmacology , vol.15 , pp. 133-142
    • Bhagwat, S.V.1    Bhamre, S.2    Boyd, M.R.3
  • 35
    • 34447269645 scopus 로고    scopus 로고
    • Pharmacogenomics and adverse drug reactions in diagnostic and clinical practice
    • V.G.Manolopoulos. Pharmacogenomics and adverse drug reactions in diagnostic and clinical practice. Clin Chem Lab Med. 2007;45:801–814.
    • (2007) Clin Chem Lab Med , vol.45 , pp. 801-814
    • Manolopoulos, V.G.1
  • 36
    • 84929032233 scopus 로고    scopus 로고
    • Clinical applications of CYP genotyping in psychiatry
    • E.Spina, J.de Leon. Clinical applications of CYP genotyping in psychiatry. J Neural Transm (Vienna). 2015;122:5–28.• Recent review focused on clinical applications of CYP genotyping.
    • (2015) J Neural Transm (Vienna) , vol.122 , pp. 5-28
    • Spina, E.1    de Leon, J.2
  • 37
    • 80051888635 scopus 로고    scopus 로고
    • Genetic polymorphisms of cytochrome P450 enzymes and antidepressant metabolism
    • S.Porcelli, C.Fabbri, E.Spina, et al. Genetic polymorphisms of cytochrome P450 enzymes and antidepressant metabolism. Expert Opin Drug Metab Toxicol. 2011;7:1101–1115.
    • (2011) Expert Opin Drug Metab Toxicol , vol.7 , pp. 1101-1115
    • Porcelli, S.1    Fabbri, C.2    Spina, E.3
  • 38
    • 0842312531 scopus 로고    scopus 로고
    • Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants
    • D.R.Nelson, D.C.Zeldin, S.M.Hoffman, et al. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Pharmacogenetics. 2004;14:1–18.
    • (2004) Pharmacogenetics , vol.14 , pp. 1-18
    • Nelson, D.R.1    Zeldin, D.C.2    Hoffman, S.M.3
  • 39
    • 0034638766 scopus 로고    scopus 로고
    • Pharmacogenetics and adverse drug reactions
    • U.A.Meyer. Pharmacogenetics and adverse drug reactions. Lancet. 2000;356:1667–1671.
    • (2000) Lancet , vol.356 , pp. 1667-1671
    • Meyer, U.A.1
  • 40
    • 79955463893 scopus 로고    scopus 로고
    • Pharmacogenetics: from bench to byte – an update of guidelines
    • J.J.Swen, M.Nijenhuis, A.De Boer, et al. Pharmacogenetics:from bench to byte – an update of guidelines. Clin Pharmacol Ther. 2011;89:662–673.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 662-673
    • Swen, J.J.1    Nijenhuis, M.2    De Boer, A.3
  • 41
    • 77950350248 scopus 로고    scopus 로고
    • Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response
    • M.-H.Tsai, K.-M.Lin, M.-C.Hsiao, et al. Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response. Pharmacogenomics. 2010;11:537–546.
    • (2010) Pharmacogenomics , vol.11 , pp. 537-546
    • Tsai, M.-H.1    Lin, K.-M.2    Hsiao, M.-C.3
  • 42
    • 44849119612 scopus 로고    scopus 로고
    • Pharmacokinetic genes do not influence response or tolerance to citalopram in the STAR*D sample
    • E.J.Peters, S.L.Slager, J.B.Kraft, et al. Pharmacokinetic genes do not influence response or tolerance to citalopram in the STAR*D sample. PLoS One. 2008;3:e1872.
    • (2008) PLoS One , vol.3 , pp. e1872
    • Peters, E.J.1    Slager, S.L.2    Kraft, J.B.3
  • 43
    • 1242269894 scopus 로고    scopus 로고
    • Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: ultrarapid metabolism of antidepressants as a cause of nonresponse. A pilot study
    • C.Kawanishi, S.Lundgren, H.Agren, et al. Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders:ultrarapid metabolism of antidepressants as a cause of nonresponse. A pilot study. Eur J Clin Pharmacol. 2004;59:803–807.
    • (2004) Eur J Clin Pharmacol , vol.59 , pp. 803-807
    • Kawanishi, C.1    Lundgren, S.2    Agren, H.3
  • 44
    • 2042512985 scopus 로고    scopus 로고
    • CYP2D6 genotype: impact on adverse effects and nonresponse during treatment with antidepressants-a pilot study
    • T.Rau, G.Wohlleben, H.Wuttke, et al. CYP2D6 genotype:impact on adverse effects and nonresponse during treatment with antidepressants-a pilot study. Clin Pharmacol Ther. 2004;75:386–393.
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 386-393
    • Rau, T.1    Wohlleben, G.2    Wuttke, H.3
  • 45
    • 77955865554 scopus 로고    scopus 로고
    • High frequency of occurrence of CYP2D6 gene duplication/multiduplication indicating ultrarapid metabolism among suicide cases
    • A.L.Zackrisson, B.Lindblom, J.Ahlner. High frequency of occurrence of CYP2D6 gene duplication/multiduplication indicating ultrarapid metabolism among suicide cases. Clin Pharmacol Ther. 2010;88:354–359.
    • (2010) Clin Pharmacol Ther , vol.88 , pp. 354-359
    • Zackrisson, A.L.1    Lindblom, B.2    Ahlner, J.3
  • 46
    • 84886653435 scopus 로고    scopus 로고
    • Towards the implementation of CYP2D6 and CYP2C19 genotypes in clinical practice: update and report from a pharmacogenetic service clinic
    • D.J.Müller, I.Kekin, A.C.Kao, et al. Towards the implementation of CYP2D6 and CYP2C19 genotypes in clinical practice:update and report from a pharmacogenetic service clinic. Int Rev Psychiatry. 2013;25:554–571.
    • (2013) Int Rev Psychiatry , vol.25 , pp. 554-571
    • Müller, D.J.1    Kekin, I.2    Kao, A.C.3
  • 47
    • 84959165252 scopus 로고    scopus 로고
    • Clinically significant pharmacokinetic drug interactions of antiepileptic drugs with new antidepressants and new antipsychotics
    • E.Spina, F.Pisani, J.de Leon. Clinically significant pharmacokinetic drug interactions of antiepileptic drugs with new antidepressants and new antipsychotics. Pharmacol Res. 2016;106:72–86.
    • (2016) Pharmacol Res , vol.106 , pp. 72-86
    • Spina, E.1    Pisani, F.2    de Leon, J.3
  • 48
    • 0035989854 scopus 로고    scopus 로고
    • Glucuronidation of olanzapine by cDNA-expressed human UDP-glucuronosyltransferases and human liver microsomes
    • K.Linnet. Glucuronidation of olanzapine by cDNA-expressed human UDP-glucuronosyltransferases and human liver microsomes. Hum Psychopharmacol. 2002;17:233–238.
    • (2002) Hum Psychopharmacol , vol.17 , pp. 233-238
    • Linnet, K.1
  • 49
    • 0033862494 scopus 로고    scopus 로고
    • Comparative N-glucuronidation kinetics of ketotifen and amitriptyline by expressed human UDP-glucuronosyltransferases and liver microsomes
    • U.Breyer-Pfaff, U.Mey, M.D.Green, et al. Comparative N-glucuronidation kinetics of ketotifen and amitriptyline by expressed human UDP-glucuronosyltransferases and liver microsomes. Drug Metab Dispos. 2000;28:869–872.
    • (2000) Drug Metab Dispos , vol.28 , pp. 869-872
    • Breyer-Pfaff, U.1    Mey, U.2    Green, M.D.3
  • 50
    • 77950932971 scopus 로고    scopus 로고
    • Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine
    • D.Zhou, J.Guo, A.J.Linnenbach, et al. Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine. Drug Metab Dispos. 2010;38:863–870.
    • (2010) Drug Metab Dispos , vol.38 , pp. 863-870
    • Zhou, D.1    Guo, J.2    Linnenbach, A.J.3
  • 51
    • 1942424750 scopus 로고    scopus 로고
    • Six novel UDP-glucuronosyltransferase (UGT1A3) polymorphisms with varying activity
    • M.Iwai, Y.Maruo, M.Ito, et al. Six novel UDP-glucuronosyltransferase (UGT1A3) polymorphisms with varying activity. J Hum Genet. 2004;49:123–128.
    • (2004) J Hum Genet , vol.49 , pp. 123-128
    • Iwai, M.1    Maruo, Y.2    Ito, M.3
  • 52
    • 17844379707 scopus 로고    scopus 로고
    • UDP-glucuronosyltransferase 1A4 polymorphisms in a Japanese population and kinetics of clozapine glucuronidation
    • A.Mori, Y.Maruo, M.Iwai, et al. UDP-glucuronosyltransferase 1A4 polymorphisms in a Japanese population and kinetics of clozapine glucuronidation. Drug Metab Dispos. 2005;33:672–675.
    • (2005) Drug Metab Dispos , vol.33 , pp. 672-675
    • Mori, A.1    Maruo, Y.2    Iwai, M.3
  • 53
    • 84921300423 scopus 로고    scopus 로고
    • A UGT2B10 splicing polymorphism common in african populations may greatly increase drug exposure
    • S.Fowler, H.Kletzl, M.Finel, et al. A UGT2B10 splicing polymorphism common in african populations may greatly increase drug exposure. J Pharmacol Exp Ther. 2015;352:358–367.
    • (2015) J Pharmacol Exp Ther , vol.352 , pp. 358-367
    • Fowler, S.1    Kletzl, H.2    Finel, M.3
  • 54
    • 84929398546 scopus 로고    scopus 로고
    • Pharmacogenetics of major depressive disorder: top genes and pathways toward clinical applications
    • C.Fabbri, A.Serretti. Pharmacogenetics of major depressive disorder:top genes and pathways toward clinical applications. Curr Psychiatry Rep. 2015;17:50.
    • (2015) Curr Psychiatry Rep , vol.17 , pp. 50
    • Fabbri, C.1    Serretti, A.2
  • 55
    • 38749113409 scopus 로고    scopus 로고
    • ABCB1 (MDR1) gene polymorphisms are associated with the clinical response to paroxetine in patients with major depressive disorder
    • M.Kato, T.Fukuda, A.Serretti, et al. ABCB1 (MDR1) gene polymorphisms are associated with the clinical response to paroxetine in patients with major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32:398–404.
    • (2008) Prog Neuropsychopharmacol Biol Psychiatry , vol.32 , pp. 398-404
    • Kato, M.1    Fukuda, T.2    Serretti, A.3
  • 56
    • 56949103059 scopus 로고    scopus 로고
    • Citalopram enantiomers in plasma and cerebrospinal fluid of ABCB1 genotyped depressive patients and clinical response: a pilot study
    • G.Nikisch, C.B.Eap, P.Baumann. Citalopram enantiomers in plasma and cerebrospinal fluid of ABCB1 genotyped depressive patients and clinical response:a pilot study. Pharmacol Res. 2008;58:344–347.
    • (2008) Pharmacol Res , vol.58 , pp. 344-347
    • Nikisch, G.1    Eap, C.B.2    Baumann, P.3
  • 57
    • 38149003759 scopus 로고    scopus 로고
    • Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression
    • M.Uhr, A.Tontsch, C.Namendorf, et al. Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression. Neuron. 2008;57:203–209.
    • (2008) Neuron , vol.57 , pp. 203-209
    • Uhr, M.1    Tontsch, A.2    Namendorf, C.3
  • 58
    • 77954957572 scopus 로고    scopus 로고
    • ABCB1 (MDR1) polymorphisms and antidepressant response in geriatric depression
    • J.E.Sarginson, L.C.Lazzeroni, H.S.Ryan, et al. ABCB1 (MDR1) polymorphisms and antidepressant response in geriatric depression. Pharmacogenet Genom. 2010;20:467–475.
    • (2010) Pharmacogenet Genom , vol.20 , pp. 467-475
    • Sarginson, J.E.1    Lazzeroni, L.C.2    Ryan, H.S.3
  • 60
    • 84938723569 scopus 로고    scopus 로고
    • ABCB1 genetic effects on antidepressant outcomes: a report from the iSPOT-D trial
    • A.F.Schatzberg, C.DeBattista, L.C.Lazzeroni, et al. ABCB1 genetic effects on antidepressant outcomes:a report from the iSPOT-D trial. Am J Psychiatry. 2015;172:751–759.
    • (2015) Am J Psychiatry , vol.172 , pp. 751-759
    • Schatzberg, A.F.1    DeBattista, C.2    Lazzeroni, L.C.3
  • 61
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophrenia-associated genetic loci
    • Schizophrenia Working Group of the Psychiatric Genomics C. Biological insights from 108 schizophrenia-associated genetic loci. Nature. 2014;511:421–427.
    • (2014) Nature , vol.511 , pp. 421-427
  • 62
    • 77951779878 scopus 로고    scopus 로고
    • Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
    • R.Uher, N.Perroud, M.Y.Ng, et al. Genome-wide pharmacogenetics of antidepressant response in the GENDEP project. Am J Psychiatry. 2010;167:555–564.
    • (2010) Am J Psychiatry , vol.167 , pp. 555-564
    • Uher, R.1    Perroud, N.2    Ng, M.Y.3
  • 63
    • 71649105262 scopus 로고    scopus 로고
    • A genomewide association study of citalopram response in major depressive disorder
    • H.A.Garriock, J.B.Kraft, S.I.Shyn, et al. A genomewide association study of citalopram response in major depressive disorder. Biol Psychiatry. 2010;67:133–138.
    • (2010) Biol Psychiatry , vol.67 , pp. 133-138
    • Garriock, H.A.1    Kraft, J.B.2    Shyn, S.I.3
  • 64
    • 69949184308 scopus 로고    scopus 로고
    • A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    • M.Ising, S.Lucae, E.B.Binder, et al. A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Arch Gen Psychiatry. 2009;66:966–975.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 966-975
    • Ising, M.1    Lucae, S.2    Binder, E.B.3
  • 65
    • 84973434910 scopus 로고    scopus 로고
    • A genome-wide association study of antidepressant response in Koreans
    • W.Myung, J.Kim, S.-W.Lim, et al. A genome-wide association study of antidepressant response in Koreans. Transl Psychiatry. 2015;5:e633.
    • (2015) Transl Psychiatry , vol.5 , pp. e633
    • Myung, W.1    Kim, J.2    Lim, S.-W.3
  • 66
    • 84990909819 scopus 로고    scopus 로고
    • The international SSRI pharmacogenomics consortium (ISPC): a genome-wide association study of antidepressant treatment response
    • J.M.Biernacka, K.Sangkuhl, G.Jenkins, et al. The international SSRI pharmacogenomics consortium (ISPC):a genome-wide association study of antidepressant treatment response. Transl Psychiatry. 2015;5:e553.
    • (2015) Transl Psychiatry , vol.5 , pp. e553
    • Biernacka, J.M.1    Sangkuhl, K.2    Jenkins, G.3
  • 67
    • 84881174811 scopus 로고    scopus 로고
    • Possible association of CUX1 gene polymorphisms with antidepressant response in major depressive disorder
    • D.Sasayama, A.Hiraishi, M.Tatsumi, et al. Possible association of CUX1 gene polymorphisms with antidepressant response in major depressive disorder. Pharmacogenomics J. 2013;13:354–358.
    • (2013) Pharmacogenomics J , vol.13 , pp. 354-358
    • Sasayama, D.1    Hiraishi, A.2    Tatsumi, M.3
  • 68
    • 84914106962 scopus 로고    scopus 로고
    • Clinical outcomes and genome-wide association for a brain methylation site in an antidepressant pharmacogenetics study in Mexican Americans
    • M.-L.Wong, C.Dong, D.L.Flores, et al. Clinical outcomes and genome-wide association for a brain methylation site in an antidepressant pharmacogenetics study in Mexican Americans. Am J Psychiatry. 2014;171:1297–1309.
    • (2014) Am J Psychiatry , vol.171 , pp. 1297-1309
    • Wong, M.-L.1    Dong, C.2    Flores, D.L.3
  • 69
    • 84883876168 scopus 로고    scopus 로고
    • Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression
    • A.Tammiste, T.Jiang, K.Fischer, et al. Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression. J Psychopharmacol. 2013;27:915–920.
    • (2013) J Psychopharmacol , vol.27 , pp. 915-920
    • Tammiste, A.1    Jiang, T.2    Fischer, K.3
  • 70
    • 84922683827 scopus 로고    scopus 로고
    • Rare copy number variation in treatment-resistant major depressive disorder
    • C.O’Dushlaine, S.Ripke, D.M.Ruderfer, et al. Rare copy number variation in treatment-resistant major depressive disorder. Biol Psychiatry. 2014;76:536–541.
    • (2014) Biol Psychiatry , vol.76 , pp. 536-541
    • O’Dushlaine, C.1    Ripke, S.2    Ruderfer, D.M.3
  • 71
    • 84904960520 scopus 로고    scopus 로고
    • Copy number variants and therapeutic response to antidepressant medication in major depressive disorder
    • K.E.Tansey, J.J.Rucker, D.H.Kavanagh, et al. Copy number variants and therapeutic response to antidepressant medication in major depressive disorder. Pharmacogenomics J. 2014;14:395–399.
    • (2014) Pharmacogenomics J , vol.14 , pp. 395-399
    • Tansey, K.E.1    Rucker, J.J.2    Kavanagh, D.H.3
  • 72
    • 84884416967 scopus 로고    scopus 로고
    • The role of AUTS2 in neurodevelopment and human evolution
    • N.Oksenberg, N.Ahituv. The role of AUTS2 in neurodevelopment and human evolution. Trends Genet. 2013;29:600–608.
    • (2013) Trends Genet , vol.29 , pp. 600-608
    • Oksenberg, N.1    Ahituv, N.2
  • 73
    • 67650924855 scopus 로고    scopus 로고
    • Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept
    • M.L.Hamshere, E.K.Green, I.R.Jones, et al. Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept. Br J Psychiatry. 2009;195:23–29.
    • (2009) Br J Psychiatry , vol.195 , pp. 23-29
    • Hamshere, M.L.1    Green, E.K.2    Jones, I.R.3
  • 74
    • 72049127779 scopus 로고    scopus 로고
    • Preliminary genome-wide association study of bipolar disorder in the Japanese population
    • E.Hattori, T.Toyota, Y.Ishitsuka, et al. Preliminary genome-wide association study of bipolar disorder in the Japanese population. Am J Med Genet B Neuropsychiatr Genet. 2009;150B:1110–1117.
    • (2009) Am J Med Genet B Neuropsychiatr Genet , vol.150B , pp. 1110-1117
    • Hattori, E.1    Toyota, T.2    Ishitsuka, Y.3
  • 75
    • 84964237812 scopus 로고    scopus 로고
    • Association of a brain methylation site with clinical outcomes in depression does not replicate across populations
    • R.Uher, S.Ripke, B.Müller-Myhsok, et al. Association of a brain methylation site with clinical outcomes in depression does not replicate across populations. Am J Psychiatry. 2015;172:395–397.
    • (2015) Am J Psychiatry , vol.172 , pp. 395-397
    • Uher, R.1    Ripke, S.2    Müller-Myhsok, B.3
  • 76
    • 84880135878 scopus 로고    scopus 로고
    • A genome-wide association study of a sustained pattern of antidepressant response
    • A.M.Hunter, A.F.Leuchter, R.A.Power, et al. A genome-wide association study of a sustained pattern of antidepressant response. J Psychiatr Res. 2013;47:1157–1165.
    • (2013) J Psychiatr Res , vol.47 , pp. 1157-1165
    • Hunter, A.M.1    Leuchter, A.F.2    Power, R.A.3
  • 77
    • 84947486882 scopus 로고    scopus 로고
    • Neuronal cell adhesion genes and antidepressant response in three independent samples
    • C.Fabbri, C.Crisafulli, D.Gurwitz, et al. Neuronal cell adhesion genes and antidepressant response in three independent samples. Pharmacogenomics J. 2015;15:538–548.
    • (2015) Pharmacogenomics J , vol.15 , pp. 538-548
    • Fabbri, C.1    Crisafulli, C.2    Gurwitz, D.3
  • 78
    • 27344432023 scopus 로고    scopus 로고
    • Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory
    • S.Moosmang, N.Haider, N.Klugbauer, et al. Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory. J Neurosci. 2005;25:9883–9892.
    • (2005) J Neurosci , vol.25 , pp. 9883-9892
    • Moosmang, S.1    Haider, N.2    Klugbauer, N.3
  • 79
    • 36549030795 scopus 로고    scopus 로고
    • Stress, depression, and neuroplasticity: a convergence of mechanisms
    • C.Pittenger, R.S.Duman. Stress, depression, and neuroplasticity:a convergence of mechanisms. Neuropsychopharmacology. 2008;33:88–109.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 88-109
    • Pittenger, C.1    Duman, R.S.2
  • 80
    • 84884165962 scopus 로고    scopus 로고
    • Neurogenesis along the septo-temporal axis of the hippocampus: are depression and the action of antidepressants region-specific?
    • A.Tanti, C.Belzung. Neurogenesis along the septo-temporal axis of the hippocampus:are depression and the action of antidepressants region-specific? Neuroscience. 2013;252:234–252.
    • (2013) Neuroscience , vol.252 , pp. 234-252
    • Tanti, A.1    Belzung, C.2
  • 81
    • 84880649467 scopus 로고    scopus 로고
    • Emerging complexity of the HuD/ELAVl4 gene; implications for neuronal development, function, and dysfunction
    • L.M.Bronicki, B.J.Jasmin. Emerging complexity of the HuD/ELAVl4 gene; implications for neuronal development, function, and dysfunction. Rna. 2013;19:1019–1037.
    • (2013) Rna , vol.19 , pp. 1019-1037
    • Bronicki, L.M.1    Jasmin, B.J.2
  • 82
    • 80455149918 scopus 로고    scopus 로고
    • Antidepressants stimulate hippocampal neurogenesis by inhibiting p21 expression in the subgranular zone of the hipppocampus
    • R.N.Pechnick, S.Zonis, K.Wawrowsky, et al. Antidepressants stimulate hippocampal neurogenesis by inhibiting p21 expression in the subgranular zone of the hipppocampus. PLoS One. 2011;6:e27290.
    • (2011) PLoS One , vol.6 , pp. e27290
    • Pechnick, R.N.1    Zonis, S.2    Wawrowsky, K.3
  • 83
    • 84884283816 scopus 로고    scopus 로고
    • Increased hippocampal neurogenesis and p21 expression in depression: dependent on antidepressants, sex, age, and antipsychotic exposure
    • J.R.Epp, C.L.Beasley, L.A.Galea. Increased hippocampal neurogenesis and p21 expression in depression:dependent on antidepressants, sex, age, and antipsychotic exposure. Neuropsychopharmacology. 2013;38:2297–2306.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 2297-2306
    • Epp, J.R.1    Beasley, C.L.2    Galea, L.A.3
  • 84
    • 84855398593 scopus 로고    scopus 로고
    • DHHC-7 and −21 are palmitoylacyltransferases for sex steroid receptors
    • A.Pedram, M.Razandi, R.J.Deschenes, et al. DHHC-7 and −21 are palmitoylacyltransferases for sex steroid receptors. Mol Biol Cell. 2012;23:188–199.
    • (2012) Mol Biol Cell , vol.23 , pp. 188-199
    • Pedram, A.1    Razandi, M.2    Deschenes, R.J.3
  • 85
    • 84861194813 scopus 로고    scopus 로고
    • Modulation of synaptic plasticity in the hippocampus by hippocampus-derived estrogen and androgen
    • Y.Ooishi, S.Kawato, Y.Hojo, et al. Modulation of synaptic plasticity in the hippocampus by hippocampus-derived estrogen and androgen. J Steroid Biochem Mol Biol. 2012;131:37–51.
    • (2012) J Steroid Biochem Mol Biol , vol.131 , pp. 37-51
    • Ooishi, Y.1    Kawato, S.2    Hojo, Y.3
  • 86
    • 78149256605 scopus 로고    scopus 로고
    • Gender differences in depression
    • G.Parker, H.Brotchie. Gender differences in depression. Int Rev Psychiatry. 2010;22:429–436.
    • (2010) Int Rev Psychiatry , vol.22 , pp. 429-436
    • Parker, G.1    Brotchie, H.2
  • 87
    • 33751527786 scopus 로고    scopus 로고
    • Chronic antidepressant treatment selectively increases expression of plasticity-related proteins in the hippocampus and medial prefrontal cortex of the rat
    • M.Sairanen, O.F.O’Leary, J.E.Knuuttila, et al. Chronic antidepressant treatment selectively increases expression of plasticity-related proteins in the hippocampus and medial prefrontal cortex of the rat. Neuroscience. 2007;144:368–374.
    • (2007) Neuroscience , vol.144 , pp. 368-374
    • Sairanen, M.1    O’Leary, O.F.2    Knuuttila, J.E.3
  • 88
    • 48049112584 scopus 로고    scopus 로고
    • Effects of repeated citalopram treatments on chronic mild stress-induced growth associated protein-43 mRNA expression in rat hippocampus
    • S.-H.Park, S.-H.Choi, J.Lee, et al. Effects of repeated citalopram treatments on chronic mild stress-induced growth associated protein-43 mRNA expression in rat hippocampus. Korean J Physiol Pharmacol. 2008;12:117–123.
    • (2008) Korean J Physiol Pharmacol , vol.12 , pp. 117-123
    • Park, S.-H.1    Choi, S.-H.2    Lee, J.3
  • 89
    • 84943357496 scopus 로고    scopus 로고
    • Inflammation and clinical response to treatment in depression: a meta-analysis
    • R.Strawbridge, D.Arnone, A.Danese, et al. Inflammation and clinical response to treatment in depression:a meta-analysis. Eur Neuropsychopharmacol. 2015;25:1532–1543.•• Recent meta-analysis of inflammatory biomarkers associated with antidepressant response and treatment resistance.
    • (2015) Eur Neuropsychopharmacol , vol.25 , pp. 1532-1543
    • Strawbridge, R.1    Arnone, D.2    Danese, A.3
  • 90
    • 84864759986 scopus 로고    scopus 로고
    • Neuroplastic changes in depression: a role for the immune system
    • H.Eyre, B.T.Baune. Neuroplastic changes in depression:a role for the immune system. Psychoneuroendocrinology. 2012;37:1397–1416.
    • (2012) Psychoneuroendocrinology , vol.37 , pp. 1397-1416
    • Eyre, H.1    Baune, B.T.2
  • 91
    • 84992212817 scopus 로고    scopus 로고
    • Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia
    • S.P.Hagenaars, S.E.Harris, G.Davies, et al. Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia. Mol Psychiatry. 2016. [Epub ahead of print].
    • (2016) Mol Psychiatry
    • Hagenaars, S.P.1    Harris, S.E.2    Davies, G.3
  • 92
    • 84875134648 scopus 로고    scopus 로고
    • Contribution of common genetic variants to antidepressant response
    • K.E.Tansey, M.Guipponi, X.Hu, et al. Contribution of common genetic variants to antidepressant response. Biol Psychiatry. 2013;73:679–682.• This study provided the first estimation of the contribution of common variants to the variance in antidepressant response.
    • (2013) Biol Psychiatry , vol.73 , pp. 679-682
    • Tansey, K.E.1    Guipponi, M.2    Hu, X.3
  • 93
    • 84885705541 scopus 로고    scopus 로고
    • On the outside, looking in: a review and evaluation of the comparability of blood and brain “-omes
    • D.S.Tylee, D.M.Kawaguchi, S.J.Glatt. On the outside, looking in:a review and evaluation of the comparability of blood and brain “-omes”. Am J Med Genet B Neuropsychiatr Genet. 2013;162B:595–603.
    • (2013) Am J Med Genet B Neuropsychiatr Genet , vol.162B , pp. 595-603
    • Tylee, D.S.1    Kawaguchi, D.M.2    Glatt, S.J.3
  • 94
    • 77949658730 scopus 로고    scopus 로고
    • Reduced peripheral brain-derived neurotrophic factor mRNA levels are normalized by antidepressant treatment
    • A.Cattaneo, L.Bocchio-Chiavetto, R.Zanardini, et al. Reduced peripheral brain-derived neurotrophic factor mRNA levels are normalized by antidepressant treatment. Int J Neuropsychopharmacol. 2010;13:103–108.
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 103-108
    • Cattaneo, A.1    Bocchio-Chiavetto, L.2    Zanardini, R.3
  • 95
    • 84884211454 scopus 로고    scopus 로고
    • Epigenetic regulation of BDNF expression according to antidepressant response
    • J.P.Lopez, F.Mamdani, B.Labonte, et al. Epigenetic regulation of BDNF expression according to antidepressant response. Mol Psychiatry. 2013;18:398–399.
    • (2013) Mol Psychiatry , vol.18 , pp. 398-399
    • Lopez, J.P.1    Mamdani, F.2    Labonte, B.3
  • 96
    • 80052789637 scopus 로고    scopus 로고
    • Serum brain-derived neurotrophic factor and glucocorticoid receptor levels in lymphocytes as markers of antidepressant response in major depressive patients: a pilot study
    • P.S.Rojas, R.Fritsch, R.A.Rojas, et al. Serum brain-derived neurotrophic factor and glucocorticoid receptor levels in lymphocytes as markers of antidepressant response in major depressive patients:a pilot study. Psychiatry Res. 2011;189:239–245.
    • (2011) Psychiatry Res , vol.189 , pp. 239-245
    • Rojas, P.S.1    Fritsch, R.2    Rojas, R.A.3
  • 97
    • 79959550112 scopus 로고    scopus 로고
    • Gene expression biomarkers of response to citalopram treatment in major depressive disorder
    • F.Mamdani, M.T.Berlim, M.-M.Beaulieu, et al. Gene expression biomarkers of response to citalopram treatment in major depressive disorder. Transl Psychiatry. 2011;1:e13.
    • (2011) Transl Psychiatry , vol.1 , pp. e13
    • Mamdani, F.1    Berlim, M.T.2    Beaulieu, M.-M.3
  • 98
    • 84989328975 scopus 로고    scopus 로고
    • RNA expression profiling in depressed patients suggests retinoid-related orphan receptor alpha as a biomarker for antidepressant response
    • J.M.Hennings, M.Uhr, T.Klengel, et al. RNA expression profiling in depressed patients suggests retinoid-related orphan receptor alpha as a biomarker for antidepressant response. Transl Psychiatry. 2015;5:e538.
    • (2015) Transl Psychiatry , vol.5 , pp. e538
    • Hennings, J.M.1    Uhr, M.2    Klengel, T.3
  • 99
    • 84869756304 scopus 로고    scopus 로고
    • Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode
    • R.Belzeaux, A.Bergon, V.Jeanjean, et al. Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode. Transl Psychiatry. 2012;2:e185.
    • (2012) Transl Psychiatry , vol.2 , pp. e185
    • Belzeaux, R.1    Bergon, A.2    Jeanjean, V.3
  • 100
    • 84922105083 scopus 로고    scopus 로고
    • Testing the predictive value of peripheral gene expression for nonremission following citalopram treatment for major depression
    • J.-P.Guilloux, S.Bassi, Y.Ding, et al. Testing the predictive value of peripheral gene expression for nonremission following citalopram treatment for major depression. Neuropsychopharmacology. 2015;40:701–710.
    • (2015) Neuropsychopharmacology , vol.40 , pp. 701-710
    • Guilloux, J.-P.1    Bassi, S.2    Ding, Y.3
  • 101
    • 84880452154 scopus 로고    scopus 로고
    • Psychiatric pharmacogenomics predicts health resource utilization of outpatients with anxiety and depression
    • J.Winner, J.D.Allen, C.A.Altar, et al. Psychiatric pharmacogenomics predicts health resource utilization of outpatients with anxiety and depression. Transl Psychiatry. 2013;3:e242.
    • (2013) Transl Psychiatry , vol.3 , pp. e242
    • Winner, J.1    Allen, J.D.2    Altar, C.A.3
  • 102
    • 84885082776 scopus 로고    scopus 로고
    • Utility of integrated pharmacogenomic testing to support the treatment of major depressive disorder in a psychiatric outpatient setting
    • D.K.Hall-Flavin, J.G.Winner, J.D.Allen, et al. Utility of integrated pharmacogenomic testing to support the treatment of major depressive disorder in a psychiatric outpatient setting. Pharmacogenet Genom. 2013;23:535–548.
    • (2013) Pharmacogenet Genom , vol.23 , pp. 535-548
    • Hall-Flavin, D.K.1    Winner, J.G.2    Allen, J.D.3
  • 103
    • 84971658653 scopus 로고    scopus 로고
    • Combinatorial pharmacogenomic guidance for psychiatric medications reduces overall pharmacy costs in a 1 year prospective evaluation
    • J.G.Winner, J.M.Carhart, C.A.Altar, et al. Combinatorial pharmacogenomic guidance for psychiatric medications reduces overall pharmacy costs in a 1 year prospective evaluation. Curr Med Res Opin. 2015;31:1633–1643.
    • (2015) Curr Med Res Opin , vol.31 , pp. 1633-1643
    • Winner, J.G.1    Carhart, J.M.2    Altar, C.A.3
  • 104
    • 84881372143 scopus 로고    scopus 로고
    • Folate metabolism genes, dietary folate and response to antidepressant medications in late-life depression
    • B.D.Jamerson, M.E.Payne, M.E.Garrett, et al. Folate metabolism genes, dietary folate and response to antidepressant medications in late-life depression. Int J Geriatr Psychiatry. 2013;28:925–932.
    • (2013) Int J Geriatr Psychiatry , vol.28 , pp. 925-932
    • Jamerson, B.D.1    Payne, M.E.2    Garrett, M.E.3
  • 105
    • 84878676824 scopus 로고    scopus 로고
    • Intranasal infusion of melanocortin receptor four (MC4R) antagonist to rats ameliorates development of depression and anxiety related symptoms induced by single prolonged stress
    • L.I.Serova, M.Laukova, L.G.Alaluf, et al. Intranasal infusion of melanocortin receptor four (MC4R) antagonist to rats ameliorates development of depression and anxiety related symptoms induced by single prolonged stress. Behav Brain Res. 2013;250:139–147.
    • (2013) Behav Brain Res , vol.250 , pp. 139-147
    • Serova, L.I.1    Laukova, M.2    Alaluf, L.G.3
  • 106
    • 77951778072 scopus 로고    scopus 로고
    • Association of mu-opioid receptor variants and response to citalopram treatment in major depressive disorder
    • H.A.Garriock, M.Tanowitz, J.B.Kraft, et al. Association of mu-opioid receptor variants and response to citalopram treatment in major depressive disorder. Am J Psychiatry. 2010;167:565–573.
    • (2010) Am J Psychiatry , vol.167 , pp. 565-573
    • Garriock, H.A.1    Tanowitz, M.2    Kraft, J.B.3
  • 107
    • 84944339610 scopus 로고    scopus 로고
    • A naturalistic study of the effectiveness of pharmacogenetic testing to guide treatment in psychiatric patients with mood and anxiety disorders
    • F.X.Brennan, K.R.Gardner, J.Lombard, et al. A naturalistic study of the effectiveness of pharmacogenetic testing to guide treatment in psychiatric patients with mood and anxiety disorders. Prim Care Companion CNS Disord. 2015;17:e1–e7.
    • (2015) Prim Care Companion CNS Disord , vol.17 , pp. e1-e7
    • Brennan, F.X.1    Gardner, K.R.2    Lombard, J.3
  • 108
    • 84903625870 scopus 로고    scopus 로고
    • Pharmacogenetic-guided psychiatric intervention associated with increased adherence and cost savings
    • J.Fagerness, E.Fonseca, G.P.Hess, et al. Pharmacogenetic-guided psychiatric intervention associated with increased adherence and cost savings. Am J Manag Care. 2014;20:e146–e156.
    • (2014) Am J Manag Care , vol.20 , pp. e146-e156
    • Fagerness, J.1    Fonseca, E.2    Hess, G.P.3
  • 109
    • 84939542012 scopus 로고    scopus 로고
    • Improved antidepressant remission in major depression via a pharmacokinetic pathway polygene pharmacogenetic report
    • A.B.Singh. Improved antidepressant remission in major depression via a pharmacokinetic pathway polygene pharmacogenetic report. Clin Psychopharmacol Neurosci. 2015;13:150–156.
    • (2015) Clin Psychopharmacol Neurosci , vol.13 , pp. 150-156
    • Singh, A.B.1
  • 110
    • 84901707207 scopus 로고    scopus 로고
    • The clinical application of ABCB1 genotyping in antidepressant treatment: a pilot study
    • B.Breitenstein, S.Scheuer, H.Pfister, et al. The clinical application of ABCB1 genotyping in antidepressant treatment:a pilot study. CNS Spectr. 2014;19:165–175.
    • (2014) CNS Spectr , vol.19 , pp. 165-175
    • Breitenstein, B.1    Scheuer, S.2    Pfister, H.3
  • 111
    • 84958985482 scopus 로고    scopus 로고
    • Association of ABCB1 gene variants, plasma antidepressant concentration, and treatment response: results from a randomized clinical study
    • B.Breitenstein, S.Scheuer, T.M.Brückl, et al. Association of ABCB1 gene variants, plasma antidepressant concentration, and treatment response:results from a randomized clinical study. J Psychiatr Res. 2016;73:86–95.
    • (2016) J Psychiatr Res , vol.73 , pp. 86-95
    • Breitenstein, B.1    Scheuer, S.2    Brückl, T.M.3
  • 112
    • 84952005660 scopus 로고    scopus 로고
    • The FKBP5 polymorphism rs1360780 influences the effect of an algorithm-based antidepressant treatment and is associated with remission in patients with major depression
    • T.J.Stamm, C.Rampp, K.Wiethoff, et al. The FKBP5 polymorphism rs1360780 influences the effect of an algorithm-based antidepressant treatment and is associated with remission in patients with major depression. J Psychopharmacol. 2016;30:40–47.
    • (2016) J Psychopharmacol , vol.30 , pp. 40-47
    • Stamm, T.J.1    Rampp, C.2    Wiethoff, K.3
  • 113
    • 84919958417 scopus 로고    scopus 로고
    • Clinical application of pharmacogenomics: the example of HLA-based drug-induced toxicity
    • M.T.Lee, S.Mahasirimongkol, Y.Zhang, et al. Clinical application of pharmacogenomics:the example of HLA-based drug-induced toxicity. Public Health Genom. 2014;17:248–255.
    • (2014) Public Health Genom , vol.17 , pp. 248-255
    • Lee, M.T.1    Mahasirimongkol, S.2    Zhang, Y.3
  • 114
    • 84884609038 scopus 로고    scopus 로고
    • Pharmacogenetics of mood disorders: what clinicians need to know
    • G.Laje. Pharmacogenetics of mood disorders:what clinicians need to know. CNS Spectr. 2013;18:272–284.
    • (2013) CNS Spectr , vol.18 , pp. 272-284
    • Laje, G.1
  • 115
    • 82555190925 scopus 로고    scopus 로고
    • Should pharmacogenetics be incorporated in major depression treatment? Economic evaluation in high- and middle-income European countries
    • P.Olgiati, E.Bajo, M.Bigelli, et al. Should pharmacogenetics be incorporated in major depression treatment? Economic evaluation in high- and middle-income European countries. Prog Neuropsychopharmacol Biol Psychiatry. 2012;36:147–154.
    • (2012) Prog Neuropsychopharmacol Biol Psychiatry , vol.36 , pp. 147-154
    • Olgiati, P.1    Bajo, E.2    Bigelli, M.3
  • 116
    • 85007201789 scopus 로고    scopus 로고
    • Perspectives on genetic and genomic technologies in an academic medical center: the duke experience
    • S.H.Katsanis, M.A.Minear, A.Vorderstrasse, et al. Perspectives on genetic and genomic technologies in an academic medical center:the duke experience. J Pers Med. 2015;5:67–82.
    • (2015) J Pers Med , vol.5 , pp. 67-82
    • Katsanis, S.H.1    Minear, M.A.2    Vorderstrasse, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.