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Volumn 79, Issue 1, 2016, Pages 25-31

Common polymorphisms in the age of research domain criteria (RDoC): Integration and translation

Author keywords

Anxiety; BDNF Val66Met; Behavioral dimension; Common polymorphism; Fear learning; Genetic biomarker

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

EID: 84948458945     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2014.12.020     Document Type: Review
Times cited : (19)

References (75)
  • 1
    • 84898752877 scopus 로고    scopus 로고
    • The NIMH Research Domain Criteria (RDoC) Project: Precision medicine for psychiatry
    • T.R. Insel The NIMH Research Domain Criteria (RDoC) Project: Precision medicine for psychiatry Am J Psychiatry 171 2014 395 397
    • (2014) Am J Psychiatry , vol.171 , pp. 395-397
    • Insel, T.R.1
  • 2
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophrenia-associated genetic loci
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium Biological insights from 108 schizophrenia-associated genetic loci Nature 511 2014 421 427
    • (2014) Nature , vol.511 , pp. 421-427
  • 3
    • 84862493260 scopus 로고    scopus 로고
    • Genetic architecture in autism spectrum disorder
    • B. Devlin, and S.W. Scherer Genetic architecture in autism spectrum disorder Curr Opin Genet Dev 22 2012 229 237
    • (2012) Curr Opin Genet Dev , vol.22 , pp. 229-237
    • Devlin, B.1    Scherer, S.W.2
  • 4
    • 84901608878 scopus 로고    scopus 로고
    • Large-scale genomics unveils the genetic architecture of psychiatric disorders
    • J. Gratten, N.R. Wray, M.C. Keller, and P.M. Visscher Large-scale genomics unveils the genetic architecture of psychiatric disorders Nat Neurosci 17 2014 782 790
    • (2014) Nat Neurosci , vol.17 , pp. 782-790
    • Gratten, J.1    Wray, N.R.2    Keller, M.C.3    Visscher, P.M.4
  • 5
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • N. Risch, and K. Merikangas The future of genetic studies of complex human diseases Science 273 1996 1516 1517
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 6
    • 0030688004 scopus 로고    scopus 로고
    • Variations on a theme: Cataloging human DNA sequence variation
    • F.S. Collins, M.S. Guyer, and A. Charkravarti Variations on a theme: Cataloging human DNA sequence variation Science 278 1997 1580 1581
    • (1997) Science , vol.278 , pp. 1580-1581
    • Collins, F.S.1    Guyer, M.S.2    Charkravarti, A.3
  • 7
    • 0029805706 scopus 로고    scopus 로고
    • The new genomics: Global views of biology
    • E.S. Lander The new genomics: Global views of biology Science 274 1996 536 539
    • (1996) Science , vol.274 , pp. 536-539
    • Lander, E.S.1
  • 8
    • 0035451780 scopus 로고    scopus 로고
    • On the allelic spectrum of human disease
    • D.E. Reich, and E.S. Lander On the allelic spectrum of human disease Trends Genet 17 2001 502 510
    • (2001) Trends Genet , vol.17 , pp. 502-510
    • Reich, D.E.1    Lander, E.S.2
  • 9
    • 73949152919 scopus 로고    scopus 로고
    • Narrowing the boundaries of the genetic architecture of schizophrenia
    • N.R. Wray, and P.M. Visscher Narrowing the boundaries of the genetic architecture of schizophrenia Schizophr Bull 36 2010 14 23
    • (2010) Schizophr Bull , vol.36 , pp. 14-23
    • Wray, N.R.1    Visscher, P.M.2
  • 10
    • 77955359525 scopus 로고    scopus 로고
    • Genome-wide association study of major recurrent depression in the U.K. Population
    • C.M. Lewis, M.Y. Ng, A.W. Butler, S. Cohen-Woods, R. Uher, K. Pirlo, and et al. Genome-wide association study of major recurrent depression in the U.K. population Am J Psychiatry 167 2010 949 957
    • (2010) Am J Psychiatry , vol.167 , pp. 949-957
    • Lewis, C.M.1    Ng, M.Y.2    Butler, A.W.3    Cohen-Woods, S.4    Uher, R.5    Pirlo, K.6
  • 12
    • 84920645919 scopus 로고    scopus 로고
    • From psychiatric disorders to animal models: A bidirectional and dimensional approach
    • Z.R. Donaldson, and R. Hen From psychiatric disorders to animal models: A bidirectional and dimensional approach Biol Psychiatry 77 2015 15 21
    • (2015) Biol Psychiatry , vol.77 , pp. 15-21
    • Donaldson, Z.R.1    Hen, R.2
  • 14
    • 77957273984 scopus 로고    scopus 로고
    • Animal models of neuropsychiatric disorders
    • E.J. Nestler, and S.E. Hyman Animal models of neuropsychiatric disorders Nat Neurosci 13 2010 1161 1169
    • (2010) Nat Neurosci , vol.13 , pp. 1161-1169
    • Nestler, E.J.1    Hyman, S.E.2
  • 15
    • 0034927081 scopus 로고    scopus 로고
    • Neurotrophins: Roles in neuronal development and function
    • E.J. Huang, and L.F. Reichardt Neurotrophins: Roles in neuronal development and function Annu Rev Neurosci 24 2001 677 736
    • (2001) Annu Rev Neurosci , vol.24 , pp. 677-736
    • Huang, E.J.1    Reichardt, L.F.2
  • 16
    • 0038730942 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor/TrkB signaling in memory processes
    • K. Yamada, and T. Nabeshima Brain-derived neurotrophic factor/TrkB signaling in memory processes J Pharmacol Sci 91 2003 267 270
    • (2003) J Pharmacol Sci , vol.91 , pp. 267-270
    • Yamada, K.1    Nabeshima, T.2
  • 17
    • 23944445784 scopus 로고    scopus 로고
    • Activity-dependent modulation of the BDNF receptor TrkB: Mechanisms and implications
    • G. Nagappan, and B. Lu Activity-dependent modulation of the BDNF receptor TrkB: Mechanisms and implications Trends Neurosci 28 2005 464 471
    • (2005) Trends Neurosci , vol.28 , pp. 464-471
    • Nagappan, G.1    Lu, B.2
  • 18
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • - 1000 Genomes Project Consortium, G.R. Abecasis, D. Altshuler, A. Auton, L.D. Brooks, R.M. Durbin, and et al. A map of human genome variation from population-scale sequencing Nature 467 2010 1061 1073
    • (2010) Nature , vol.467 , pp. 1061-1073
    • Abecasis, G.R.1    Altshuler, D.2    Auton, A.3    Brooks, L.D.4    Durbin, R.M.5
  • 19
    • 21544461501 scopus 로고    scopus 로고
    • Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway
    • Z.Y. Chen, A. Ieraci, H. Teng, H. Dall, C.X. Meng, D.G. Herrera, and et al. Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway J Neurosci 25 2005 6156 6166
    • (2005) J Neurosci , vol.25 , pp. 6156-6166
    • Chen, Z.Y.1    Ieraci, A.2    Teng, H.3    Dall, H.4    Meng, C.X.5    Herrera, D.G.6
  • 20
    • 33749649795 scopus 로고    scopus 로고
    • Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior
    • Z.Y. Chen, D. Jing, K.G. Bath, A. Ieraci, T. Khan, C.J. Siao, and et al. Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior Science 314 2006 140 143
    • (2006) Science , vol.314 , pp. 140-143
    • Chen, Z.Y.1    Jing, D.2    Bath, K.G.3    Ieraci, A.4    Khan, T.5    Siao, C.J.6
  • 21
    • 0037462449 scopus 로고    scopus 로고
    • The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
    • M.F. Egan, M. Kojima, J.H. Callicott, T.E. Goldberg, B.S. Kolachana, A. Bertolino, and et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function Cell 112 2003 257 269
    • (2003) Cell , vol.112 , pp. 257-269
    • Egan, M.F.1    Kojima, M.2    Callicott, J.H.3    Goldberg, T.E.4    Kolachana, B.S.5    Bertolino, A.6
  • 22
    • 84860351187 scopus 로고    scopus 로고
    • Impact of the BDNF Val66Met polymorphism on cognition: Implications for behavioral genetics
    • I. Dincheva, C.E. Glatt, and F.S. Lee Impact of the BDNF Val66Met polymorphism on cognition: Implications for behavioral genetics Neuroscientist 18 2012 439 451
    • (2012) Neuroscientist , vol.18 , pp. 439-451
    • Dincheva, I.1    Glatt, C.E.2    Lee, F.S.3
  • 23
    • 8544249878 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology
    • L. Pezawas, B.A. Verchinski, V.S. Mattay, J.H. Callicott, B.S. Kolachana, R.E. Straub, and et al. The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology J Neurosci 24 2004 10099 10102
    • (2004) J Neurosci , vol.24 , pp. 10099-10102
    • Pezawas, L.1    Verchinski, B.A.2    Mattay, V.S.3    Callicott, J.H.4    Kolachana, B.S.5    Straub, R.E.6
  • 24
    • 0032535354 scopus 로고    scopus 로고
    • Fear and the brain: Where have we been, and where are we going?
    • J. LeDoux Fear and the brain: Where have we been, and where are we going? Biol Psychiatry 44 1998 1229 1238
    • (1998) Biol Psychiatry , vol.44 , pp. 1229-1238
    • LeDoux, J.1
  • 25
    • 0034076609 scopus 로고    scopus 로고
    • Emotion circuits in the brain
    • J.E. LeDoux Emotion circuits in the brain Annu Rev Neurosci 23 2000 155 184
    • (2000) Annu Rev Neurosci , vol.23 , pp. 155-184
    • LeDoux, J.E.1
  • 26
    • 84878261678 scopus 로고    scopus 로고
    • The contextual brain: Implications for fear conditioning, extinction and psychopathology
    • S. Maren, K.L. Phan, and I. Liberzon The contextual brain: Implications for fear conditioning, extinction and psychopathology Nat Rev Neurosci 14 2013 417 428
    • (2013) Nat Rev Neurosci , vol.14 , pp. 417-428
    • Maren, S.1    Phan, K.L.2    Liberzon, I.3
  • 27
    • 84873851437 scopus 로고    scopus 로고
    • Implications of memory modulation for post-traumatic stress and fear disorders
    • R.G. Parsons, and K.J. Ressler Implications of memory modulation for post-traumatic stress and fear disorders Nat Neurosci 16 2013 146 153
    • (2013) Nat Neurosci , vol.16 , pp. 146-153
    • Parsons, R.G.1    Ressler, K.J.2
  • 28
    • 84871720291 scopus 로고    scopus 로고
    • Individual differences in recovery from traumatic fear
    • A. Holmes, and N. Singewald Individual differences in recovery from traumatic fear Trends Neurosci 36 2013 23 31
    • (2013) Trends Neurosci , vol.36 , pp. 23-31
    • Holmes, A.1    Singewald, N.2
  • 30
    • 70449467156 scopus 로고    scopus 로고
    • Linking dimensional models of internalizing psychopathology to neurobiological systems: Affect-modulated startle as an indicator of fear and distress disorders and affiliated traits
    • U. Vaidyanathan, C.J. Patrick, and B.N. Cuthbert Linking dimensional models of internalizing psychopathology to neurobiological systems: Affect-modulated startle as an indicator of fear and distress disorders and affiliated traits Psychol Bull 135 2009 909 942
    • (2009) Psychol Bull , vol.135 , pp. 909-942
    • Vaidyanathan, U.1    Patrick, C.J.2    Cuthbert, B.N.3
  • 31
    • 76749151013 scopus 로고    scopus 로고
    • A genetic variant BDNF polymorphism alters extinction learning in both mouse and human
    • F. Soliman, C.E. Glatt, K.G. Bath, L. Levita, R.M. Jones, S.S. Pattwell, and et al. A genetic variant BDNF polymorphism alters extinction learning in both mouse and human Science 327 2010 863 866
    • (2010) Science , vol.327 , pp. 863-866
    • Soliman, F.1    Glatt, C.E.2    Bath, K.G.3    Levita, L.4    Jones, R.M.5    Pattwell, S.S.6
  • 32
    • 34147142830 scopus 로고    scopus 로고
    • Recalling safety: Cooperative functions of the ventromedial prefrontal cortex and the hippocampus in extinction
    • K.A. Corcoran, and G.J. Quirk Recalling safety: Cooperative functions of the ventromedial prefrontal cortex and the hippocampus in extinction CNS Spectr 12 2007 200 206
    • (2007) CNS Spectr , vol.12 , pp. 200-206
    • Corcoran, K.A.1    Quirk, G.J.2
  • 33
    • 34250783547 scopus 로고    scopus 로고
    • Recall of fear extinction in humans activates the ventromedial prefrontal cortex and hippocampus in concert
    • M.R. Milad, C.I. Wright, S.P. Orr, R.K. Pitman, G.J. Quirk, and S.L. Rauch Recall of fear extinction in humans activates the ventromedial prefrontal cortex and hippocampus in concert Biol Psychiatry 62 2007 446 454
    • (2007) Biol Psychiatry , vol.62 , pp. 446-454
    • Milad, M.R.1    Wright, C.I.2    Orr, S.P.3    Pitman, R.K.4    Quirk, G.J.5    Rauch, S.L.6
  • 34
    • 84890440439 scopus 로고    scopus 로고
    • Synaptic regulation of affective behaviors; Role of BDNF
    • I. Ninan Synaptic regulation of affective behaviors; role of BDNF Neuropharmacology 76 2014 684 695
    • (2014) Neuropharmacology , vol.76 , pp. 684-695
    • Ninan, I.1
  • 35
    • 84857089131 scopus 로고    scopus 로고
    • The BDNF Val66Met polymorphism impairs synaptic transmission and plasticity in the infralimbic medial prefrontal cortex
    • S.S. Pattwell, K.G. Bath, R. Perez-Castro, F.S. Lee, M.V. Chao, and I. Ninan The BDNF Val66Met polymorphism impairs synaptic transmission and plasticity in the infralimbic medial prefrontal cortex J Neurosci 32 2012 2410 2421
    • (2012) J Neurosci , vol.32 , pp. 2410-2421
    • Pattwell, S.S.1    Bath, K.G.2    Perez-Castro, R.3    Lee, F.S.4    Chao, M.V.5    Ninan, I.6
  • 36
    • 84903965902 scopus 로고    scopus 로고
    • A neurodevelopmental perspective on the research domain criteria (RDoC) framework
    • B.J. Casey, M.E. Oliveri, and T. Insel A neurodevelopmental perspective on the research domain criteria (RDoC) framework Biol Psychiatry 76 2014 350 353
    • (2014) Biol Psychiatry , vol.76 , pp. 350-353
    • Casey, B.J.1    Oliveri, M.E.2    Insel, T.3
  • 37
    • 77955716777 scopus 로고    scopus 로고
    • Impaired extinction retention in adolescent rats: Effects of D-cycloserine
    • J. McCallum, J.H. Kim, and R. Richardson Impaired extinction retention in adolescent rats: Effects of D-cycloserine Neuropsychopharmacology 35 2010 2134 2142
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2134-2142
    • McCallum, J.1    Kim, J.H.2    Richardson, R.3
  • 39
    • 78649332949 scopus 로고    scopus 로고
    • Neurobiology of the adolescent brain and behavior: Implications for substance use disorders
    • quiz 1285
    • B.J. Casey, and R.M. Jones Neurobiology of the adolescent brain and behavior: Implications for substance use disorders J Am Acad Child Adolesc Psychiatry 49 2010 1189 1201 quiz 1285
    • (2010) J Am Acad Child Adolesc Psychiatry , vol.49 , pp. 1189-1201
    • Casey, B.J.1    Jones, R.M.2
  • 40
    • 77950154827 scopus 로고    scopus 로고
    • The storm and stress of adolescence: Insights from human imaging and mouse genetics
    • B.J. Casey, R.M. Jones, L. Levita, V. Libby, S.S. Pattwell, E.J. Ruberry, and et al. The storm and stress of adolescence: Insights from human imaging and mouse genetics Dev Psychobiol 52 2010 225 235
    • (2010) Dev Psychobiol , vol.52 , pp. 225-235
    • Casey, B.J.1    Jones, R.M.2    Levita, L.3    Libby, V.4    Pattwell, S.S.5    Ruberry, E.J.6
  • 42
    • 79551624514 scopus 로고    scopus 로고
    • Selective early-acquired fear memories undergo temporary suppression during adolescence
    • S.S. Pattwell, K.G. Bath, B.J. Casey, I. Ninan, and F.S. Lee Selective early-acquired fear memories undergo temporary suppression during adolescence Proc Natl Acad Sci U S A 108 2011 1182 1187
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 1182-1187
    • Pattwell, S.S.1    Bath, K.G.2    Casey, B.J.3    Ninan, I.4    Lee, F.S.5
  • 43
    • 84883349535 scopus 로고    scopus 로고
    • Fear learning and memory across adolescent development: Hormones and Behavior Special Issue: Puberty and Adolescence
    • S.S. Pattwell, F.S. Lee, and B.J. Casey Fear learning and memory across adolescent development: Hormones and Behavior Special Issue: Puberty and Adolescence Horm Behav 64 2013 380 389
    • (2013) Horm Behav , vol.64 , pp. 380-389
    • Pattwell, S.S.1    Lee, F.S.2    Casey, B.J.3
  • 45
    • 84865207047 scopus 로고    scopus 로고
    • Variant brain-derived neurotrophic factor (Valine66Methionine) polymorphism contributes to developmental and estrous stage-specific expression of anxiety-like behavior in female mice
    • K.G. Bath, J. Chuang, J.L. Spencer-Segal, D. Amso, M. Altemus, B.S. McEwen, and F.S. Lee Variant brain-derived neurotrophic factor (Valine66Methionine) polymorphism contributes to developmental and estrous stage-specific expression of anxiety-like behavior in female mice Biol Psychiatry 72 2012 499 504
    • (2012) Biol Psychiatry , vol.72 , pp. 499-504
    • Bath, K.G.1    Chuang, J.2    Spencer-Segal, J.L.3    Amso, D.4    Altemus, M.5    McEwen, B.S.6    Lee, F.S.7
  • 46
    • 80054100023 scopus 로고    scopus 로고
    • Stress and anxiety: Structural plasticity and epigenetic regulation as a consequence of stress
    • B.S. McEwen, L. Eiland, R.G. Hunter, and M.M. Miller Stress and anxiety: Structural plasticity and epigenetic regulation as a consequence of stress Neuropharmacology 62 2012 3 12
    • (2012) Neuropharmacology , vol.62 , pp. 3-12
    • McEwen, B.S.1    Eiland, L.2    Hunter, R.G.3    Miller, M.M.4
  • 47
    • 67349157695 scopus 로고    scopus 로고
    • Effects of stress throughout the lifespan on the brain, behaviour and cognition
    • S.J. Lupien, B.S. McEwen, M.R. Gunnar, and C. Heim Effects of stress throughout the lifespan on the brain, behaviour and cognition Nat Rev Neurosci 10 2009 434 445
    • (2009) Nat Rev Neurosci , vol.10 , pp. 434-445
    • Lupien, S.J.1    McEwen, B.S.2    Gunnar, M.R.3    Heim, C.4
  • 48
    • 84863380672 scopus 로고    scopus 로고
    • Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants
    • H. Yu, D.D. Wang, Y. Wang, T. Liu, F.S. Lee, and Z.Y. Chen Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants J Neurosci 32 2012 4092 4101
    • (2012) J Neurosci , vol.32 , pp. 4092-4101
    • Yu, H.1    Wang, D.D.2    Wang, Y.3    Liu, T.4    Lee, F.S.5    Chen, Z.Y.6
  • 49
    • 80054925531 scopus 로고    scopus 로고
    • A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development
    • R.P. Juster, G. Bizik, M. Picard, G. Arsenault-Lapierre, S. Sindi, L. Trepanier, and et al. A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development Dev Psychopathol 23 2011 725 776
    • (2011) Dev Psychopathol , vol.23 , pp. 725-776
    • Juster, R.P.1    Bizik, G.2    Picard, M.3    Arsenault-Lapierre, G.4    Sindi, S.5    Trepanier, L.6
  • 50
    • 84887406857 scopus 로고    scopus 로고
    • Amygdala FAAH and anandamide: Mediating protection and recovery from stress
    • O. Gunduz-Cinar, M.N. Hill, B.S. McEwen, and A. Holmes Amygdala FAAH and anandamide: Mediating protection and recovery from stress Trends Pharmacol Sci 34 2013 637 644
    • (2013) Trends Pharmacol Sci , vol.34 , pp. 637-644
    • Gunduz-Cinar, O.1    Hill, M.N.2    McEwen, B.S.3    Holmes, A.4
  • 51
    • 84879412059 scopus 로고    scopus 로고
    • Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity
    • O. Gunduz-Cinar, K.P. MacPherson, R. Cinar, J. Gamble-George, K. Sugden, B. Williams, and et al. Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity Mol Psychiatry 18 2013 813 823
    • (2013) Mol Psychiatry , vol.18 , pp. 813-823
    • Gunduz-Cinar, O.1    MacPherson, K.P.2    Cinar, R.3    Gamble-George, J.4    Sugden, K.5    Williams, B.6
  • 52
    • 13944267958 scopus 로고    scopus 로고
    • Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear
    • J.P. Chhatwal, M. Davis, K.A. Maguschak, and K.J. Ressler Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear Neuropsychopharmacology 30 2005 516 524
    • (2005) Neuropsychopharmacology , vol.30 , pp. 516-524
    • Chhatwal, J.P.1    Davis, M.2    Maguschak, K.A.3    Ressler, K.J.4
  • 53
    • 0037062436 scopus 로고    scopus 로고
    • A missense mutation in human fatty acid amide hydrolase associated with problem drug use
    • J.C. Sipe, K. Chiang, A.L. Gerber, E. Beutler, and B.F. Cravatt A missense mutation in human fatty acid amide hydrolase associated with problem drug use Proc Natl Acad Sci U S A 99 2002 8394 8399
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 8394-8399
    • Sipe, J.C.1    Chiang, K.2    Gerber, A.L.3    Beutler, E.4    Cravatt, B.F.5
  • 54
    • 5744238950 scopus 로고    scopus 로고
    • Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: Evidence for a link between defects in the endocannabinoid system and problem drug use
    • K.P. Chiang, A.L. Gerber, J.C. Sipe, and B.F. Cravatt Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: Evidence for a link between defects in the endocannabinoid system and problem drug use Hum Mol Genet 13 2004 2113 2119
    • (2004) Hum Mol Genet , vol.13 , pp. 2113-2119
    • Chiang, K.P.1    Gerber, A.L.2    Sipe, J.C.3    Cravatt, B.F.4
  • 56
    • 4644276631 scopus 로고    scopus 로고
    • Association of genetic loci: Replication or not, that is the question
    • J. Ott Association of genetic loci: Replication or not, that is the question Neurology 63 2004 955 958
    • (2004) Neurology , vol.63 , pp. 955-958
    • Ott, J.1
  • 57
    • 67649206975 scopus 로고    scopus 로고
    • Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: A meta-analysis
    • N. Risch, R. Herrell, T. Lehner, K.Y. Liang, L. Eaves, J. Hoh, and et al. Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis JAMA 301 2009 2462 2471
    • (2009) JAMA , vol.301 , pp. 2462-2471
    • Risch, N.1    Herrell, R.2    Lehner, T.3    Liang, K.Y.4    Eaves, L.5    Hoh, J.6
  • 58
    • 79952033418 scopus 로고    scopus 로고
    • The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: Evidence of genetic moderation
    • K. Karg, M. Burmeister, K. Shedden, and S. Sen The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: Evidence of genetic moderation Arch Gen Psychiatry 68 2011 444 454
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 444-454
    • Karg, K.1    Burmeister, M.2    Shedden, K.3    Sen, S.4
  • 59
    • 40149094312 scopus 로고    scopus 로고
    • The when and where of BDNF and the antidepressant response
    • J.W. Wang, A. Dranovsky, and R. Hen The when and where of BDNF and the antidepressant response Biol Psychiatry 63 2008 640 641
    • (2008) Biol Psychiatry , vol.63 , pp. 640-641
    • Wang, J.W.1    Dranovsky, A.2    Hen, R.3
  • 60
    • 77949746666 scopus 로고    scopus 로고
    • The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity
    • E. Castren, and T. Rantamaki The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity Dev Neurobiol 70 2010 289 297
    • (2010) Dev Neurobiol , vol.70 , pp. 289-297
    • Castren, E.1    Rantamaki, T.2
  • 61
    • 77952982006 scopus 로고    scopus 로고
    • How the neurocircuitry and genetics of fear inhibition may inform our understanding of PTSD
    • T. Jovanovic, and K.J. Ressler How the neurocircuitry and genetics of fear inhibition may inform our understanding of PTSD Am J Psychiatry 167 2010 648 662
    • (2010) Am J Psychiatry , vol.167 , pp. 648-662
    • Jovanovic, T.1    Ressler, K.J.2
  • 62
  • 63
    • 84877586206 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor Val66Met polymorphism predicts response to exposure therapy in posttraumatic stress disorder
    • K.L. Felmingham, C. Dobson-Stone, P.R. Schofield, G.J. Quirk, and R.A. Bryant The brain-derived neurotrophic factor Val66Met polymorphism predicts response to exposure therapy in posttraumatic stress disorder Biol Psychiatry 73 2013 1059 1063
    • (2013) Biol Psychiatry , vol.73 , pp. 1059-1063
    • Felmingham, K.L.1    Dobson-Stone, C.2    Schofield, P.R.3    Quirk, G.J.4    Bryant, R.A.5
  • 64
    • 77952420724 scopus 로고    scopus 로고
    • OPRM1 SNP (A118G): Involvement in disease development, treatment response, and animal models
    • S.D. Mague, and J.A. Blendy OPRM1 SNP (A118G): Involvement in disease development, treatment response, and animal models Drug Alcohol Depend 108 2010 172 182
    • (2010) Drug Alcohol Depend , vol.108 , pp. 172-182
    • Mague, S.D.1    Blendy, J.A.2
  • 66
    • 84862829325 scopus 로고    scopus 로고
    • Reduced expression of the mu opioid receptor in some, but not all, brain regions in mice with OPRM1 A112G
    • Y.J. Wang, P. Huang, A. Ung, J.A. Blendy, and L.Y. Liu-Chen Reduced expression of the mu opioid receptor in some, but not all, brain regions in mice with OPRM1 A112G Neuroscience 205 2012 178 184
    • (2012) Neuroscience , vol.205 , pp. 178-184
    • Wang, Y.J.1    Huang, P.2    Ung, A.3    Blendy, J.A.4    Liu-Chen, L.Y.5
  • 67
    • 84925541494 scopus 로고    scopus 로고
    • Mouse model of the OPRM1 (A118G) polymorphism: Differential heroin self-administration behavior compared with wild-type mice [published online ahead of print October 22]
    • Y. Zhang, R. Picetti, E.R. Butelman, A. Ho, J.A. Blendy, and M.J. Kreek Mouse model of the OPRM1 (A118G) polymorphism: Differential heroin self-administration behavior compared with wild-type mice [published online ahead of print October 22] Neuropsychopharmacology. 2014
    • (2014) Neuropsychopharmacology.
    • Zhang, Y.1    Picetti, R.2    Butelman, E.R.3    Ho, A.4    Blendy, J.A.5    Kreek, M.J.6
  • 68
    • 34447636936 scopus 로고    scopus 로고
    • Role of the COMT gene Val158Met polymorphism in mental disorders: A review
    • L. Hosak Role of the COMT gene Val158Met polymorphism in mental disorders: A review Eur Psychiatry 22 2007 276 281
    • (2007) Eur Psychiatry , vol.22 , pp. 276-281
    • Hosak, L.1
  • 69
    • 84897458124 scopus 로고    scopus 로고
    • Targeted genome editing tools for disease modeling and gene therapy
    • M. Cai, and Y. Yang Targeted genome editing tools for disease modeling and gene therapy Curr Gene Ther 14 2014 2 9
    • (2014) Curr Gene Ther , vol.14 , pp. 2-9
    • Cai, M.1    Yang, Y.2
  • 70
    • 84903908535 scopus 로고    scopus 로고
    • The genome editing toolbox: A spectrum of approaches for targeted modification
    • J.K. Cheng, and H.S. Alper The genome editing toolbox: A spectrum of approaches for targeted modification Curr Opin Biotechnol 30C 2014 87 94
    • (2014) Curr Opin Biotechnol , vol.30 C , pp. 87-94
    • Cheng, J.K.1    Alper, H.S.2
  • 71
    • 84871519181 scopus 로고    scopus 로고
    • TALENs: A widely applicable technology for targeted genome editing
    • J.K. Joung, and J.D. Sander TALENs: A widely applicable technology for targeted genome editing Nat Rev Mol Cell Biol 14 2013 49 55
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 49-55
    • Joung, J.K.1    Sander, J.D.2
  • 72
    • 84877707375 scopus 로고    scopus 로고
    • One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
    • H. Wang, H. Yang, C.S. Shivalila, M.M. Dawlaty, A.W. Cheng, F. Zhang, and R. Jaenisch One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering Cell 153 2013 910 918
    • (2013) Cell , vol.153 , pp. 910-918
    • Wang, H.1    Yang, H.2    Shivalila, C.S.3    Dawlaty, M.M.4    Cheng, A.W.5    Zhang, F.6    Jaenisch, R.7
  • 73
    • 0030992008 scopus 로고    scopus 로고
    • Partitioning of genetic variation between regulatory and coding gene segments: The predominance of software variation in genes encoding introvert proteins
    • A. Mitchison Partitioning of genetic variation between regulatory and coding gene segments: The predominance of software variation in genes encoding introvert proteins Immunogenetics 46 1997 46 52
    • (1997) Immunogenetics , vol.46 , pp. 46-52
    • Mitchison, A.1
  • 74
    • 0036775142 scopus 로고    scopus 로고
    • Phenomics: Fiction or the future?
    • R. Gerlai Phenomics: Fiction or the future? Trends Neurosci 25 2002 506 509
    • (2002) Trends Neurosci , vol.25 , pp. 506-509
    • Gerlai, R.1


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