메뉴 건너뛰기




Volumn 19, Issue 8, 2013, Pages 1019-1037

Emerging complexity of the HuD/ELAVl4 gene; Implications for neuronal development, function, and dysfunction

Author keywords

HuD ELAVl4; mRNA metabolism; Post transcriptional regulation; RNA binding protein

Indexed keywords

ADAM10 ENDOPEPTIDASE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BRAIN DERIVED GROWTH FACTOR; HISTONE DEACETYLASE 2; HU ANTIGEN; HU PROTEIN; INITIATION FACTOR 4A; MESSENGER RNA; MICRORNA; MYC PROTEIN; NERVE GROWTH FACTOR; NEUROMODULIN; NEUROTROPHIN 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN C FOS; PROTEIN C MYB; PROTEIN KINASE B; PROTEIN KINASE C; RNA BINDING PROTEIN; RNA POLYMERASE II; SURVIVAL MOTOR NEURON PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84880649467     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.039164.113     Document Type: Review
Times cited : (96)

References (149)
  • 1
    • 80053346432 scopus 로고    scopus 로고
    • A novel function of Tis11b/BRF1 as a regulator of Dll4 mRNA 3'-end processing
    • Desroches-Castan A, Cherradi N, Feige JJ, Ciais D. 2011. A novel function of Tis11b/BRF1 as a regulator of Dll4 mRNA 3'-end processing. Mol Biol Cell 22: 3625-3633.
    • (2011) Mol Biol Cell , vol.22 , pp. 3625-3633
    • Desroches-Castan, A.1    Cherradi, N.2    Feige, J.J.3    Ciais, D.4
  • 3
    • 33747815888 scopus 로고    scopus 로고
    • Xenopus ElrB, but not ElrA, binds RNA as an oligomer: Possible role of the linker
    • Devaux A, Colegrove-Otero LJ, Standart N. 2006. Xenopus ElrB, but not ElrA, binds RNA as an oligomer: Possible role of the linker. FEBS Lett 580: 4947-4952.
    • (2006) FEBS Lett , vol.580 , pp. 4947-4952
    • Devaux, A.1    Colegrove-Otero, L.J.2    Standart, N.3
  • 5
    • 81355142141 scopus 로고    scopus 로고
    • Non-coding RNAs in human disease
    • Esteller M. 2011. Non-coding RNAs in human disease. Nat Rev Genet 12: 861-874.
    • (2011) Nat Rev Genet , vol.12 , pp. 861-874
    • Esteller, M.1
  • 7
    • 79952390939 scopus 로고    scopus 로고
    • The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons
    • Fallini C, Zhang H, Su Y, SilaniV, Singer RH, RossollW, Bassell GJ. 2011. The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons. J Neurosci 31: 3914-3925.
    • (2011) J Neurosci , vol.31 , pp. 3914-3925
    • Fallini, C.1    Zhang, H.2    Su, Y.3    Silaniv Singer, R.H.4    Rossoll, W.5    Bassell, G.J.6
  • 8
    • 84865063851 scopus 로고    scopus 로고
    • The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth
    • Fallini C, Bassell GJ, RossollW. 2012a. The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth. Hum Mol Genet 21: 3703-3718.
    • (2012) Hum Mol Genet , vol.21 , pp. 3703-3718
    • Fallini, C.1    Bassell, G.J.2    Rossoll, W.3
  • 9
    • 84862145991 scopus 로고    scopus 로고
    • Spinal muscular atrophy: The role of SMN in axonal mRNA regulation
    • Fallini C, Bassell GJ, Rossoll W. 2012b. Spinal muscular atrophy: The role of SMN in axonal mRNA regulation. Brain Res 1462: 81-92.
    • (2012) Brain Res , vol.1462 , pp. 81-92
    • Fallini, C.1    Bassell, G.J.2    Rossoll, W.3
  • 10
    • 0032526427 scopus 로고    scopus 로고
    • Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs
    • Fan XC, Steitz JA. 1998. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J 17: 3448-3460.
    • (1998) EMBO J , vol.17 , pp. 3448-3460
    • Fan, X.C.1    Steitz, J.A.2
  • 11
    • 34547103988 scopus 로고    scopus 로고
    • Specific protein domains mediate cooperative assembly of HuR oligomers on AU-rich mRNA-destabilizing sequences
    • Fialcowitz-White EJ, Brewer BY, Ballin JD, Willis CD, Toth EA, Wilson GM. 2007. Specific protein domains mediate cooperative assembly of HuR oligomers on AU-rich mRNA-destabilizing sequences. J Biol Chem 282: 20948-20959.
    • (2007) J Biol Chem , vol.282 , pp. 20948-20959
    • Fialcowitz-White, E.J.1    Brewer, B.Y.2    Ballin, J.D.3    Willis, C.D.4    Toth, E.A.5    Wilson, G.M.6
  • 12
    • 80052968310 scopus 로고    scopus 로고
    • TDP-43 and FUS/TLS: Cellular functions and implications for neurodegeneration
    • Fiesel FC, Kahle PJ. 2011. TDP-43 and FUS/TLS: Cellular functions and implications for neurodegeneration. FEBS J 278: 3550-3568.
    • (2011) FEBS J , vol.278 , pp. 3550-3568
    • Fiesel, F.C.1    Kahle, P.J.2
  • 17
    • 46749085143 scopus 로고    scopus 로고
    • Neurogenin 2 has an essential role in development of the dentate gyrus
    • Galichet C, Guillemot F, Parras CM. 2008. Neurogenin 2 has an essential role in development of the dentate gyrus. Development 135: 2031-2041.
    • (2008) Development , vol.135 , pp. 2031-2041
    • Galichet, C.1    Guillemot, F.2    Parras, C.M.3
  • 18
    • 18244389436 scopus 로고    scopus 로고
    • The role of cerebral amyloid ? accumulation in common forms of Alzheimer disease
    • Gandy S. 2005. The role of cerebral amyloid ? accumulation in common forms of Alzheimer disease. J Clin Invest 115: 1121-1129.
    • (2005) J Clin Invest , vol.115 , pp. 1121-1129
    • Gandy, S.1
  • 19
    • 0030007491 scopus 로고    scopus 로고
    • Hel-N1/Hel-N2 proteins are bound to poly (A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation
    • Gao FB, Keene JD. 1996. Hel-N1/Hel-N2 proteins are bound to poly (A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation. J Cell Sci 109 (Pt 3): 579-589.
    • (1996) J Cell Sci , vol.109 , Issue.PART. 3 , pp. 579-589
    • Gao, F.B.1    Keene, J.D.2
  • 20
    • 2942612333 scopus 로고    scopus 로고
    • A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery
    • Gherzi R, Lee KY, Briata P, Wegmuller D, Moroni C, Karin M, Chen CY. 2004. A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. Mol Cell 14: 571-583.
    • (2004) Mol Cell , vol.14 , pp. 571-583
    • Gherzi, R.1    Lee, K.Y.2    Briata, P.3    Wegmuller, D.4    Moroni, C.5    Karin, M.6    Chen, C.Y.7
  • 21
    • 0029015816 scopus 로고
    • A conserved family of elav-like genes in vertebrates
    • Good PJ. 1995. A conserved family of elav-like genes in vertebrates. Proc Natl Acad Sci 92: 4557-4561.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 4557-4561
    • Good, P.J.1
  • 22
    • 32244433195 scopus 로고    scopus 로고
    • Loss of one HuD allele on chromosome #1p selects for amplification of the Nmyc proto-oncogene in human neuroblastoma cells
    • Grandinetti KB, Spengler BA, Biedler JL, Ross RA. 2006. Loss of one HuD allele on chromosome #1p selects for amplification of the Nmyc proto-oncogene in human neuroblastoma cells. Oncogene 25: 706-712.
    • (2006) Oncogene , vol.25 , pp. 706-712
    • Grandinetti, K.B.1    Spengler, B.A.2    Biedler, J.L.3    Ross, R.A.4
  • 25
    • 36549046563 scopus 로고    scopus 로고
    • Spatial and temporal specification of neural fates by transcription factor codes
    • Guillemot F. 2007. Spatial and temporal specification of neural fates by transcription factor codes. Development 134: 3771-3780.
    • (2007) Development , vol.134 , pp. 3771-3780
    • Guillemot, F.1
  • 27
    • 38549113982 scopus 로고    scopus 로고
    • ARED organism: Expansion of ARED reveals AU-rich element cluster variations between human and mouse
    • Halees AS, El Badrawi R, Khabar KS. 2008. ARED organism: Expansion of ARED reveals AU-rich element cluster variations between human and mouse. Nucleic Acids Res 36: D137-D140.
    • (2008) Nucleic Acids Res , vol.36
    • Halees, A.S.1    El Badrawi, R.2    Khabar, K.S.3
  • 30
    • 84867696915 scopus 로고    scopus 로고
    • ELAV mediates 3' UTR extension in the Drosophila nervous system
    • Hilgers V, Lemke SB, Levine M. 2012. ELAV mediates 3' UTR extension in the Drosophila nervous system. Genes Dev 26: 2259-2264.
    • (2012) Genes Dev , vol.26 , pp. 2259-2264
    • Hilgers, V.1    Lemke, S.B.2    Levine, M.3
  • 31
    • 53849124668 scopus 로고    scopus 로고
    • Diverse molecular functions of Hu proteins
    • Hinman MN, Lou H. 2008. Diverse molecular functions of Hu proteins. Cell Mol Life Sci 65: 3168-3181.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3168-3181
    • Hinman, M.N.1    Lou, H.2
  • 32
    • 78651094423 scopus 로고    scopus 로고
    • HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects
    • Hubers L, Valderrama-Carvajal H, Laframboise J, Timbers J, Sanchez G, Cote J. 2010. HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects. Hum Mol Genet 20: 553-579.
    • (2010) Hum Mol Genet , vol.20 , pp. 553-579
    • Hubers, L.1    Valderrama-Carvajal, H.2    Laframboise, J.3    Timbers, J.4    Sanchez, G.5    Cote, J.6
  • 33
    • 84860388339 scopus 로고    scopus 로고
    • MicroRNAs in neuronal function and dysfunction
    • Im HI, Kenny PJ. 2012. MicroRNAs in neuronal function and dysfunction. Trends Neurosci 35: 325-334.
    • (2012) Trends Neurosci , vol.35 , pp. 325-334
    • Im, H.I.1    Kenny, P.J.2
  • 34
    • 84866505114 scopus 로고    scopus 로고
    • Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability
    • Ince-Dunn G, Okano HJ, Jensen KB, Park WY, Zhong R, Ule J, Mele A, Fak JJ, Yang C, Zhang C, et al. 2012. Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability. Neuron 75: 1067-1080.
    • (2012) Neuron , vol.75 , pp. 1067-1080
    • Ince-Dunn, G.1    Okano, H.J.2    Jensen, K.B.3    Park, W.Y.4    Zhong, R.5    Ule, J.6    Mele, A.7    Fak, J.J.8    Yang, C.9    Zhang, C.10
  • 35
    • 0032570832 scopus 로고    scopus 로고
    • Gene organization and chromosome location of the neural-specific RNA binding protein Elavl4
    • Inman MV, Levy S, Mock BA, Owens GC. 1998. Gene organization and chromosome location of the neural-specific RNA binding protein Elavl4. Gene 208: 139-145.
    • (1998) Gene , vol.208 , pp. 139-145
    • Inman, M.V.1    Levy, S.2    Mock, B.A.3    Owens, G.C.4
  • 36
    • 49649128843 scopus 로고    scopus 로고
    • Hu antigen R (HuR) functions as an alternative premRNA splicing regulator of Fas apoptosis-promoting receptor on exon definition
    • Izquierdo JM. 2008. Hu antigen R (HuR) functions as an alternative premRNA splicing regulator of Fas apoptosis-promoting receptor on exon definition. J Biol Chem 283: 19077-19084.
    • (2008) J Biol Chem , vol.283 , pp. 19077-19084
    • Izquierdo, J.M.1
  • 37
    • 0031038858 scopus 로고    scopus 로고
    • Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes
    • Jain RG, Andrews LG, McGowan KM, Pekala PH, Keene JD. 1997. Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes. Mol Cell Biol 17: 954-962.
    • (1997) Mol Cell Biol , vol.17 , pp. 954-962
    • Jain, R.G.1    Andrews, L.G.2    McGowan, K.M.3    Pekala, P.H.4    Keene, J.D.5
  • 38
    • 0027425060 scopus 로고
    • The C-terminus of the ? protein is critical in amyloidogenesis
    • Jarrett JT, Berger EP, Lansbury PT Jr. 1993. The C-terminus of the ? protein is critical in amyloidogenesis. Ann N Y Acad Sci 695: 144-148.
    • (1993) Ann N y Acad Sci , vol.695 , pp. 144-148
    • Jarrett, J.T.1    Berger, E.P.2    Lansbury Jr., P.T.3
  • 39
    • 0032493757 scopus 로고    scopus 로고
    • P21waf1 mRNA contains a conserved element in its 3'-untranslated region that is bound by the Elav-like mRNA-stabilizing proteins
    • Joseph B, Orlian M, Furneaux H. 1998. p21waf1 mRNA contains a conserved element in its 3'-untranslated region that is bound by the Elav-like mRNA-stabilizing proteins. J Biol Chem 273: 20511-20516.
    • (1998) J Biol Chem , vol.273 , pp. 20511-20516
    • Joseph, B.1    Orlian, M.2    Furneaux, H.3
  • 40
    • 0033397004 scopus 로고    scopus 로고
    • Cytoplasmic localization is required for the mammalian ELAV-like protein HuD to induce neuronal differentiation
    • Kasashima K, Terashima K, Yamamoto K, Sakashita E, Sakamoto H. 1999. Cytoplasmic localization is required for the mammalian ELAV-like protein HuD to induce neuronal differentiation. Genes Cells 4: 667-683.
    • (1999) Genes Cells , vol.4 , pp. 667-683
    • Kasashima, K.1    Terashima, K.2    Yamamoto, K.3    Sakashita, E.4    Sakamoto, H.5
  • 41
    • 0037109220 scopus 로고    scopus 로고
    • Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins
    • Kasashima K, Sakashita E, Saito K, Sakamoto H. 2002. Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins. Nucleic Acids Res 30: 4519-4526.
    • (2002) Nucleic Acids Res , vol.30 , pp. 4519-4526
    • Kasashima, K.1    Sakashita, E.2    Saito, K.3    Sakamoto, H.4
  • 42
    • 34250735674 scopus 로고    scopus 로고
    • RNA regulons: Coordination of post-transcriptional events
    • Keene JD. 2007. RNA regulons: Coordination of post-transcriptional events. Nat Rev Genet 8: 533-543.
    • (2007) Nat Rev Genet , vol.8 , pp. 533-543
    • Keene, J.D.1
  • 44
    • 77956727472 scopus 로고    scopus 로고
    • Post-transcriptional control during chronic inflammation and cancer: A focus on AU-rich elements
    • Khabar KS. 2010. Post-transcriptional control during chronic inflammation and cancer: A focus on AU-rich elements. Cell Mol Life Sci 67: 2937-2955.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 2937-2955
    • Khabar, K.S.1
  • 46
    • 0027499067 scopus 로고
    • The Drosophila gene rbp9 encodes a protein that is a member of a conserved group of putative RNA binding proteins that are nervous system-specific in both flies and humans
    • Kim YJ, Baker BS. 1993. The Drosophila gene rbp9 encodes a protein that is a member of a conserved group of putative RNA binding proteins that are nervous system-specific in both flies and humans. J Neurosci 13: 1045-1056.
    • (1993) J Neurosci , vol.13 , pp. 1045-1056
    • Kim, Y.J.1    Baker, B.S.2
  • 48
    • 0028282129 scopus 로고
    • Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor
    • King PH, Levine TD, Fremeau RT Jr, Keene JD. 1994. Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor. J Neurosci 14: 1943-1952.
    • (1994) J Neurosci , vol.14 , pp. 1943-1952
    • King, P.H.1    Levine, T.D.2    Fremeau Jr., R.T.3    Keene, J.D.4
  • 49
    • 0030475890 scopus 로고    scopus 로고
    • ELAV, a Drosophila neuronspecific protein, mediates the generation of an alternatively spliced neural protein isoform
    • Koushika SP, Lisbin MJ, White K. 1996. ELAV, a Drosophila neuronspecific protein, mediates the generation of an alternatively spliced neural protein isoform. Curr Biol 6: 1634-1641.
    • (1996) Curr Biol , vol.6 , pp. 1634-1641
    • Koushika, S.P.1    Lisbin, M.J.2    White, K.3
  • 51
    • 0036894711 scopus 로고    scopus 로고
    • ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5?UTR
    • Kullmann M, Gopfert U, Siewe B, Hengst L. 2002. ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5?UTR. Genes Dev 16: 3087-3099.
    • (2002) Genes Dev , vol.16 , pp. 3087-3099
    • Kullmann, M.1    Gopfert, U.2    Siewe, B.3    Hengst, L.4
  • 52
    • 4143122397 scopus 로고    scopus 로고
    • Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs
    • Lal A, Mazan-Mamczarz K, Kawai T, Yang X, Martindale JL, Gorospe M. 2004. Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J 23: 3092-3102.
    • (2004) EMBO J , vol.23 , pp. 3092-3102
    • Lal, A.1    Mazan-Mamczarz, K.2    Kawai, T.3    Yang, X.4    Martindale, J.L.5    Gorospe, M.6
  • 53
    • 0033614369 scopus 로고    scopus 로고
    • HuD, a neuronalspecific RNA-binding protein, is a putative regulator of N-myc premRNA processing/stability in malignant human neuroblasts
    • Lazarova DL, Spengler BA, Biedler JL, Ross RA. 1999. HuD, a neuronalspecific RNA-binding protein, is a putative regulator of N-myc premRNA processing/stability in malignant human neuroblasts. Oncogene 18: 2703-2710.
    • (1999) Oncogene , vol.18 , pp. 2703-2710
    • Lazarova, D.L.1    Spengler, B.A.2    Biedler, J.L.3    Ross, R.A.4
  • 56
    • 0027314350 scopus 로고
    • Hel-N1: An autoimmune RNA-binding protein with specificity for 3' uridylaterich untranslated regions of growth factor mRNAs
    • Levine TD, Gao F, King PH, Andrews LG, Keene JD. 1993. Hel-N1: An autoimmune RNA-binding protein with specificity for 3' uridylaterich untranslated regions of growth factor mRNAs. Mol Cell Biol 13: 3494-3504.
    • (1993) Mol Cell Biol , vol.13 , pp. 3494-3504
    • Levine, T.D.1    Gao, F.2    King, P.H.3    Andrews, L.G.4    Keene, J.D.5
  • 57
    • 0032513043 scopus 로고    scopus 로고
    • Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR
    • Levy NS, Chung S, Furneaux H, Levy AP. 1998. Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR. J Biol Chem 273: 6417-6423.
    • (1998) J Biol Chem , vol.273 , pp. 6417-6423
    • Levy, N.S.1    Chung, S.2    Furneaux, H.3    Levy, A.P.4
  • 58
    • 84862790319 scopus 로고    scopus 로고
    • RNA-mediated neurodegeneration in fragile X-associated tremor/ataxia syndrome
    • Li Y, Jin P. 2012. RNA-mediated neurodegeneration in fragile X-associated tremor/ataxia syndrome. Brain Res 1462: 112-117.
    • (2012) Brain Res , vol.1462 , pp. 112-117
    • Li, Y.1    Jin, P.2
  • 59
    • 70350374222 scopus 로고    scopus 로고
    • RNA-destabilizing factor tristetraprolin negatively regulates NF-κB signaling
    • Liang J, Lei T, Song Y, Yanes N, Qi Y, Fu M. 2009. RNA-destabilizing factor tristetraprolin negatively regulates NF-κB signaling. J Biol Chem 284: 29383-29390.
    • (2009) J Biol Chem , vol.284 , pp. 29383-29390
    • Liang, J.1    Lei, T.2    Song, Y.3    Yanes, N.4    Qi, Y.5    Fu, M.6
  • 60
    • 34249875986 scopus 로고    scopus 로고
    • Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation
    • Liao B, Hu Y, Brewer G. 2007. Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation. Nat Struct Mol Biol 14: 511-518.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 511-518
    • Liao, B.1    Hu, Y.2    Brewer, G.3
  • 61
    • 72849106592 scopus 로고    scopus 로고
    • RNA processing and its regulation: Global insights into biological networks
    • Licatalosi DD, Darnell RB. 2010. RNA processing and its regulation: Global insights into biological networks. Nat Rev Genet 11: 75-87.
    • (2010) Nat Rev Genet , vol.11 , pp. 75-87
    • Licatalosi, D.D.1    Darnell, R.B.2
  • 62
    • 84869883223 scopus 로고    scopus 로고
    • Protein kinase C stimulates HuD-mediated mRNA stability and protein expression of neurotrophic factors and enhances dendritic maturation of hippocampal neurons in culture
    • Lim CS, Alkon DL. 2012. Protein kinase C stimulates HuD-mediated mRNA stability and protein expression of neurotrophic factors and enhances dendritic maturation of hippocampal neurons in culture. Hippocampus 22: 2303-2319.
    • (2012) Hippocampus , vol.22 , pp. 2303-2319
    • Lim, C.S.1    Alkon, D.L.2
  • 63
    • 0029019508 scopus 로고
    • Paraneoplastic encephalomyelitis antigens bind to the AU-rich elements of mRNA
    • Liu J, Dalmau J, Szabo A, Rosenfeld M, Huber J, Furneaux H. 1995. Paraneoplastic encephalomyelitis antigens bind to the AU-rich elements of mRNA. Neurology 45: 544-550.
    • (1995) Neurology , vol.45 , pp. 544-550
    • Liu, J.1    Dalmau, J.2    Szabo, A.3    Rosenfeld, M.4    Huber, J.5    Furneaux, H.6
  • 65
    • 0029873536 scopus 로고    scopus 로고
    • Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein
    • Ma WJ, Cheng S, Campbell C, Wright A, Furneaux H. 1996. Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein. J Biol Chem 271: 8144-8151.
    • (1996) J Biol Chem , vol.271 , pp. 8144-8151
    • Ma, W.J.1    Cheng, S.2    Campbell, C.3    Wright, A.4    Furneaux, H.5
  • 66
    • 0030821226 scopus 로고    scopus 로고
    • The Elav-like proteins bind to AUrich elements and to the poly(A) tail of mRNA
    • Ma WJ, Chung S, Furneaux H. 1997. The Elav-like proteins bind to AUrich elements and to the poly(A) tail of mRNA. Nucleic Acids Res 25: 3564-3569.
    • (1997) Nucleic Acids Res , vol.25 , pp. 3564-3569
    • Ma, W.J.1    Chung, S.2    Furneaux, H.3
  • 68
    • 0035153488 scopus 로고    scopus 로고
    • Failure to express GAP-43 during neurogenesis affects cell cycle regulation and differentiation of neural precursors and stimulates apoptosis of neurons
    • Mani S, Shen Y, Schaefer J, Meiri KF. 2001. Failure to express GAP-43 during neurogenesis affects cell cycle regulation and differentiation of neural precursors and stimulates apoptosis of neurons. Mol Cell Neurosci 17: 54-66.
    • (2001) Mol Cell Neurosci , vol.17 , pp. 54-66
    • Mani, S.1    Shen, Y.2    Schaefer, J.3    Meiri, K.F.4
  • 70
    • 60049097909 scopus 로고    scopus 로고
    • The ribonome: A dominant force in coordinating gene expression
    • Mansfield KD, Keene JD. 2009. The ribonome: A dominant force in coordinating gene expression. Biol Cell 101: 169-181.
    • (2009) Biol Cell , vol.101 , pp. 169-181
    • Mansfield, K.D.1    Keene, J.D.2
  • 71
    • 84859355676 scopus 로고    scopus 로고
    • Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation
    • Mansfield KD, Keene JD. 2011. Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation. Nucleic Acids Res 40: 2734-2746.
    • (2011) Nucleic Acids Res , vol.40 , pp. 2734-2746
    • Mansfield, K.D.1    Keene, J.D.2
  • 74
    • 24344452361 scopus 로고    scopus 로고
    • A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain
    • McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA. 2005. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol 5: 14.
    • (2005) BMC Dev Biol , vol.5 , pp. 14
    • McKee, A.E.1    Minet, E.2    Stern, C.3    Riahi, S.4    Stiles, C.D.5    Silver, P.A.6
  • 75
    • 20144386175 scopus 로고    scopus 로고
    • The ELAV RNA-stability factor HuR binds the 5'-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation
    • Meng Z, King PH, Nabors LB, Jackson NL, Chen CY, Emanuel PD, Blume SW. 2005. The ELAV RNA-stability factor HuR binds the 5'-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation. Nucleic Acids Res 33: 2962-2979.
    • (2005) Nucleic Acids Res , vol.33 , pp. 2962-2979
    • Meng, Z.1    King, P.H.2    Nabors, L.B.3    Jackson, N.L.4    Chen, C.Y.5    Emanuel, P.D.6    Blume, S.W.7
  • 76
    • 0030969572 scopus 로고    scopus 로고
    • A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer
    • Min H, Turck CW, Nikolic JM, Black DL. 1997. A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer. Genes Dev 11: 1023-1036.
    • (1997) Genes Dev , vol.11 , pp. 1023-1036
    • Min, H.1    Turck, C.W.2    Nikolic, J.M.3    Black, D.L.4
  • 78
    • 33646875518 scopus 로고    scopus 로고
    • CUG-BP binds to RNA substrates and recruits PARN deadenylase
    • Moraes KC, Wilusz CJ, Wilusz J. 2006. CUG-BP binds to RNA substrates and recruits PARN deadenylase. RNA 12: 1084-1091.
    • (2006) RNA , vol.12 , pp. 1084-1091
    • Moraes, K.C.1    Wilusz, C.J.2    Wilusz, J.3
  • 80
    • 0037245474 scopus 로고    scopus 로고
    • Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2
    • Mukhopadhyay D, Houchen CW, Kennedy S, Dieckgraefe BK, Anant S. 2003. Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2. Mol Cell 11: 113-126.
    • (2003) Mol Cell , vol.11 , pp. 113-126
    • Mukhopadhyay, D.1    Houchen, C.W.2    Kennedy, S.3    Dieckgraefe, B.K.4    Anant, S.5
  • 81
    • 0027144483 scopus 로고
    • Mapping of the gene coding for a paraneoplastic encephalomyelitis antigen (HuD) to human chromosome site 1p34
    • Muresu R, Baldini A, Gress T, Posner JB, Furneaux HM, Siniscalco M. 1994. Mapping of the gene coding for a paraneoplastic encephalomyelitis antigen (HuD) to human chromosome site 1p34. Cytogenet Cell Genet 65: 177-178.
    • (1994) Cytogenet Cell Genet , vol.65 , pp. 177-178
    • Muresu, R.1    Baldini, A.2    Gress, T.3    Posner, J.B.4    Furneaux, H.M.5    Siniscalco, M.6
  • 82
    • 79952083938 scopus 로고    scopus 로고
    • Regulation and expression of elrD1 and elrD2 transcripts during early Xenopus laevis development
    • Nassar F. 2011. Regulation and expression of elrD1 and elrD2 transcripts during early Xenopus laevis development. Int J Dev Biol 55: 127-132.
    • (2011) Int J Dev Biol , vol.55 , pp. 127-132
    • Nassar, F.1
  • 83
    • 0034816779 scopus 로고    scopus 로고
    • Characterization of two promoters of the Xenopus laevis elrD gene
    • Nassar F, Wegnez M. 2001. Characterization of two promoters of the Xenopus laevis elrD gene. Biochem Biophys Res Commun 283: 392-398.
    • (2001) Biochem Biophys Res Commun , vol.283 , pp. 392-398
    • Nassar, F.1    Wegnez, M.2
  • 86
    • 0030909816 scopus 로고    scopus 로고
    • A hierarchy of Hu RNA binding proteins in developing and adult neurons
    • Okano HJ, Darnell RB. 1997. A hierarchy of Hu RNA binding proteins in developing and adult neurons. J Neurosci 17: 3024-3037.
    • (1997) J Neurosci , vol.17 , pp. 3024-3037
    • Okano, H.J.1    Darnell, R.B.2
  • 87
    • 4544245080 scopus 로고    scopus 로고
    • Poly(A)-binding proteininteracting protein 2, a strong regulator of vascular endothelial growth factor mRNA
    • Onesto C, Berra E, Grepin R, Pages G. 2004. Poly(A)-binding proteininteracting protein 2, a strong regulator of vascular endothelial growth factor mRNA. J Biol Chem 279: 34217-34226.
    • (2004) J Biol Chem , vol.279 , pp. 34217-34226
    • Onesto, C.1    Berra, E.2    Grepin, R.3    Pages, G.4
  • 88
    • 0034086060 scopus 로고    scopus 로고
    • HuD RNA recognition motifs play distinct roles in the formation of a stable complex with AU-rich RNA
    • Park S, Myszka DG, Yu M, Littler SJ, Laird-Offringa IA. 2000. HuD RNA recognition motifs play distinct roles in the formation of a stable complex with AU-rich RNA. Mol Cell Biol 20: 4765-4772.
    • (2000) Mol Cell Biol , vol.20 , pp. 4765-4772
    • Park, S.1    Myszka, D.G.2    Yu, M.3    Littler, S.J.4    Laird-Offringa, I.A.5
  • 89
    • 84857044531 scopus 로고    scopus 로고
    • The complex world of post-transcriptional mechanisms: Is their deregulation a common link for diseases? Focus on ELAV-like RNA-binding proteins
    • Pascale A, Govoni S. 2012. The complex world of post-transcriptional mechanisms: Is their deregulation a common link for diseases? Focus on ELAV-like RNA-binding proteins. Cell Mol Life Sci 69: 501-517.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 501-517
    • Pascale, A.1    Govoni, S.2
  • 90
    • 0842342611 scopus 로고    scopus 로고
    • Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory
    • Pascale A, Gusev PA, Amadio M, Dottorini T, Govoni S, Alkon DL, Quattrone A. 2004. Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory. Proc Natl Acad Sci 101: 1217-1222.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 1217-1222
    • Pascale, A.1    Gusev, P.A.2    Amadio, M.3    Dottorini, T.4    Govoni, S.5    Alkon, D.L.6    Quattrone, A.7
  • 93
    • 0032526417 scopus 로고    scopus 로고
    • RNA stabilization by the AUrich element binding protein, HuR, an ELAV protein
    • Peng SS, Chen CY, Xu N, Shyu AB. 1998. RNA stabilization by the AUrich element binding protein, HuR, an ELAV protein. EMBO J 17: 3461-3470.
    • (1998) EMBO J , vol.17 , pp. 3461-3470
    • Peng, S.S.1    Chen, C.Y.2    Xu, N.3    Shyu, A.B.4
  • 94
    • 84883227317 scopus 로고    scopus 로고
    • Role of HuD in nervous system function and pathology
    • Perrone-Bizzozero N, Bird CW. 2013. Role of HuD in nervous system function and pathology. Front Biosci (Schol Ed) 5: 554-563.
    • (2013) Front Biosci (Schol Ed) , vol.5 , pp. 554-563
    • Perrone-Bizzozero, N.1    Bird, C.W.2
  • 95
    • 84857017739 scopus 로고    scopus 로고
    • Increased expression of axogenesis-related genes and mossy fibre length in dentate granule cells from adult HuD overexpressor mice
    • Perrone-Bizzozero NI, Tanner DC, Mounce J, Bolognani F. 2011. Increased expression of axogenesis-related genes and mossy fibre length in dentate granule cells from adult HuD overexpressor mice. ASN Neuro 3: 259-270.
    • (2011) ASN Neuro , vol.3 , pp. 259-270
    • Perrone-Bizzozero, N.I.1    Tanner, D.C.2    Mounce, J.3    Bolognani, F.4
  • 96
    • 84856855006 scopus 로고    scopus 로고
    • Cullin 4B is recruited to tristetraprolincontaining messenger ribonucleoproteins and regulates TNF-? mRNA polysome loading
    • Pfeiffer JR, Brooks SA. 2012. Cullin 4B is recruited to tristetraprolincontaining messenger ribonucleoproteins and regulates TNF-? mRNA polysome loading. J Immunol 188: 1828-1839.
    • (2012) J Immunol , vol.188 , pp. 1828-1839
    • Pfeiffer, J.R.1    Brooks, S.A.2
  • 97
    • 0032076126 scopus 로고    scopus 로고
    • Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy
    • Philips AV, Timchenko LT, Cooper TA. 1998. Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy. Science 280: 737-741.
    • (1998) Science , vol.280 , pp. 737-741
    • Philips, A.V.1    Timchenko, L.T.2    Cooper, T.A.3
  • 99
    • 34548810305 scopus 로고    scopus 로고
    • Analysis of turnover and translation regulatory RNA-binding protein expression through binding to cognate mRNAs
    • Pullmann R Jr, Kim HH, Abdelmohsen K, Lal A, Martindale JL, Yang X, Gorospe M. 2007. Analysis of turnover and translation regulatory RNA-binding protein expression through binding to cognate mRNAs. Mol Cell Biol 27: 6265-6278.
    • (2007) Mol Cell Biol , vol.27 , pp. 6265-6278
    • Pullmann Jr., R.1    Kim, H.H.2    Abdelmohsen, K.3    Lal, A.4    Martindale, J.L.5    Yang, X.6    Gorospe, M.7
  • 100
  • 101
    • 0035949678 scopus 로고    scopus 로고
    • Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins
    • Quattrone A, Pascale A, Nogues X, Zhao W, Gusev P, Pacini A, Alkon DL. 2001. Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins. Proc Natl Acad Sci 98: 11668-11673.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 11668-11673
    • Quattrone, A.1    Pascale, A.2    Nogues, X.3    Zhao, W.4    Gusev, P.5    Pacini, A.6    Alkon, D.L.7
  • 103
    • 43149124205 scopus 로고    scopus 로고
    • Post-transcriptional regulation of neuro-oncological ventral antigen 1 by the neuronal RNA-binding proteins ELAV
    • Ratti A, Fallini C, Colombrita C, Pascale A, Laforenza U, Quattrone A, Silani V. 2008. Post-transcriptional regulation of neuro-oncological ventral antigen 1 by the neuronal RNA-binding proteins ELAV. J Biol Chem 283: 7531-7541.
    • (2008) J Biol Chem 283 , pp. 7531-7541
    • Ratti, A.1    Fallini, C.2    Colombrita, C.3    Pascale, A.4    Laforenza, U.5    Quattrone, A.6    Silani, V.7
  • 104
    • 0024290216 scopus 로고
    • The elav gene product of Drosophila, required in neurons, has three RNP consensus motifs
    • Robinow S, Campos AR, Yao KM, White K. 1988. The elav gene product of Drosophila, required in neurons, has three RNP consensus motifs. Science 242: 1570-1572.
    • (1988) Science , vol.242 , pp. 1570-1572
    • Robinow, S.1    Campos, A.R.2    Yao, K.M.3    White, K.4
  • 105
    • 0031418058 scopus 로고    scopus 로고
    • HuD, a neuronal-specific RNA-binding protein, is a potential regulator of MYCN expression in human neuroblastoma cells
    • Ross RA, Lazarova DL, Manley GT, Smitt PS, Spengler BA, Posner JB, Biedler JL. 1997. HuD, a neuronal-specific RNA-binding protein, is a potential regulator of MYCN expression in human neuroblastoma cells. Eur J Cancer 33: 2071-2074.
    • (1997) Eur J Cancer , vol.33 , pp. 2071-2074
    • Ross, R.A.1    Lazarova, D.L.2    Manley, G.T.3    Smitt, P.S.4    Spengler, B.A.5    Posner, J.B.6    Biedler, J.L.7
  • 109
    • 3242808974 scopus 로고    scopus 로고
    • TAP/NXF1, the primary mRNA export receptor, specifically interacts with a neuronal RNA-binding protein HuD
    • Saito K, Fujiwara T, Katahira J, Inoue K, Sakamoto H. 2004. TAP/NXF1, the primary mRNA export receptor, specifically interacts with a neuronal RNA-binding protein HuD. Biochem Biophys Res Commun 321: 291-297.
    • (2004) Biochem Biophys Res Commun , vol.321 , pp. 291-297
    • Saito, K.1    Fujiwara, T.2    Katahira, J.3    Inoue, K.4    Sakamoto, H.5
  • 111
    • 0031657747 scopus 로고    scopus 로고
    • Evidence for 3' untranslated region-dependent autoregulation of the Drosophila gene encoding the neuronal nuclear RNA-binding protein ELAV
    • Samson ML. 1998. Evidence for 3' untranslated region-dependent autoregulation of the Drosophila gene encoding the neuronal nuclear RNA-binding protein ELAV. Genetics 150: 723-733.
    • (1998) Genetics , vol.150 , pp. 723-733
    • Samson, M.L.1
  • 112
    • 0037365474 scopus 로고    scopus 로고
    • Found in neurons, a third member of the Drosophila elav gene family, encodes a neuronal protein and interacts with elav
    • Samson ML, Chalvet F. 2003. found in neurons, a third member of the Drosophila elav gene family, encodes a neuronal protein and interacts with elav. Mech Dev 120: 373-383.
    • (2003) Mech Dev , vol.120 , pp. 373-383
    • Samson, M.L.1    Chalvet, F.2
  • 116
    • 0028136928 scopus 로고
    • Molecular analysis of the HuD gene encoding a paraneoplastic encephalomyelitis antigen in human lung cancer cell lines
    • Sekido Y, Bader SA, Carbone DP, Johnson BE, Minna JD. 1994. Molecular analysis of the HuD gene encoding a paraneoplastic encephalomyelitis antigen in human lung cancer cell lines. Cancer Res 54: 4988-4992.
    • (1994) Cancer Res , vol.54 , pp. 4988-4992
    • Sekido, Y.1    Bader, S.A.2    Carbone, D.P.3    Johnson, B.E.4    Minna, J.D.5
  • 117
    • 53849122281 scopus 로고    scopus 로고
    • Both cell-autonomous and cell non-autonomous functions of GAP-43 are required for normal patterning of the cerebellum in vivo
    • Shen Y, Mishra R, Mani S, Meiri KF. 2008. Both cell-autonomous and cell non-autonomous functions of GAP-43 are required for normal patterning of the cerebellum in vivo. Cerebellum 7: 451-466.
    • (2008) Cerebellum , vol.7 , pp. 451-466
    • Shen, Y.1    Mishra, R.2    Mani, S.3    Meiri, K.F.4
  • 119
    • 12244288387 scopus 로고    scopus 로고
    • RNA trafficking and stabilization elements associate with multiple brain proteins
    • Snee M, Kidd GJ, Munro TP, Smith R. 2002. RNA trafficking and stabilization elements associate with multiple brain proteins. J Cell Sci 115: 4661-4669.
    • (2002) J Cell Sci , vol.115 , pp. 4661-4669
    • Snee, M.1    Kidd, G.J.2    Munro, T.P.3    Smith, R.4
  • 120
    • 0142027935 scopus 로고    scopus 로고
    • ELAV inhibits 3'-end processing to promote neural splicing of ewg pre-mRNA
    • Soller M, White K. 2003. ELAV inhibits 3'-end processing to promote neural splicing of ewg pre-mRNA. Genes Dev 17: 2526-2538.
    • (2003) Genes Dev , vol.17 , pp. 2526-2538
    • Soller, M.1    White, K.2
  • 123
    • 80052962642 scopus 로고    scopus 로고
    • TDP-43 and FUS/TLS: Sending a complex message about messenger RNA in amyotrophic lateral sclerosis?
    • Strong MJ, Volkening K. 2011. TDP-43 and FUS/TLS: Sending a complex message about messenger RNA in amyotrophic lateral sclerosis? FEBS J 278: 3569-3577.
    • (2011) FEBS J , vol.278 , pp. 3569-3577
    • Strong, M.J.1    Volkening, K.2
  • 124
    • 0026094583 scopus 로고
    • HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal
    • Szabo A, Dalmau J, Manley G, Rosenfeld M, Wong E, Henson J, Posner JB, Furneaux HM. 1991. HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal. Cell 67: 325-333.
    • (1991) Cell , vol.67 , pp. 325-333
    • Szabo, A.1    Dalmau, J.2    Manley, G.3    Rosenfeld, M.4    Wong, E.5    Henson, J.6    Posner, J.B.7    Furneaux, H.M.8
  • 125
    • 26244459242 scopus 로고    scopus 로고
    • Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin
    • Takagi M, Absalon MJ, McLure KG, Kastan MB. 2005. Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin. Cell 123: 49-63.
    • (2005) Cell , vol.123 , pp. 49-63
    • Takagi, M.1    Absalon, M.J.2    McLure, K.G.3    Kastan, M.B.4
  • 126
    • 50249093922 scopus 로고    scopus 로고
    • Alterations in mossy fiber physiology and GAP-43 expression and function in transgenic mice overexpressing HuD
    • Tanner DC, Qiu S, Bolognani F, Partridge LD, Weeber EJ, Perrone-Bizzozero NI. 2008. Alterations in mossy fiber physiology and GAP-43 expression and function in transgenic mice overexpressing HuD. Hippocampus 18: 814-823.
    • (2008) Hippocampus , vol.18 , pp. 814-823
    • Tanner, D.C.1    Qiu, S.2    Bolognani, F.3    Partridge, L.D.4    Weeber, E.J.5    Perrone-Bizzozero, N.I.6
  • 128
    • 0033570899 scopus 로고    scopus 로고
    • CUG repeat binding protein (CUGBP1) interacts with the 5' region of C/EBPβ mRNA and regulates translation of C/EBPβ isoforms
    • Timchenko NA, Welm AL, Lu X, Timchenko LT. 1999. CUG repeat binding protein (CUGBP1) interacts with the 5' region of C/EBPβ mRNA and regulates translation of C/EBPβ isoforms. Nucleic Acids Res 27: 4517-4525.
    • (1999) Nucleic Acids Res , vol.27 , pp. 4517-4525
    • Timchenko, N.A.1    Welm, A.L.2    Lu, X.3    Timchenko, L.T.4
  • 129
    • 56749175390 scopus 로고    scopus 로고
    • Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain
    • Tiruchinapalli DM, Caron MG, Keene JD. 2008a. Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain. J Neurochem 107: 1529-1543.
    • (2008) J Neurochem , vol.107 , pp. 1529-1543
    • Tiruchinapalli, D.M.1    Caron, M.G.2    Keene, J.D.3
  • 130
    • 56749106535 scopus 로고    scopus 로고
    • Activity-dependent expression of RNA binding protein HuD and its association with mRNAs in neurons
    • Tiruchinapalli DM, Ehlers MD, Keene JD. 2008b. Activity-dependent expression of RNA binding protein HuD and its association with mRNAs in neurons. RNA Biol 5: 157-168.
    • (2008) RNA Biol , vol.5 , pp. 157-168
    • Tiruchinapalli, D.M.1    Ehlers, M.D.2    Keene, J.D.3
  • 131
    • 40249108471 scopus 로고    scopus 로고
    • The third RNA recognition motif of Drosophila ELAV protein has a role in multimerization
    • Toba G, White K. 2008. The third RNA recognition motif of Drosophila ELAV protein has a role in multimerization. Nucleic Acids Res 36: 1390-1399.
    • (2008) Nucleic Acids Res , vol.36 , pp. 1390-1399
    • Toba, G.1    White, K.2
  • 132
    • 0036617811 scopus 로고    scopus 로고
    • Ectopic expression of Drosophila ELAV and human HuD in Drosophila wing disc cells reveals functional distinctions and similarities
    • Toba G, Qui J, Koushika SP, White K. 2002. Ectopic expression of Drosophila ELAV and human HuD in Drosophila wing disc cells reveals functional distinctions and similarities. J Cell Sci 115: 2413-2421.
    • (2002) J Cell Sci , vol.115 , pp. 2413-2421
    • Toba, G.1    Qui, J.2    Koushika, S.P.3    White, K.4
  • 133
    • 0031037486 scopus 로고    scopus 로고
    • Post-transcriptional regulation of the GAP-43 gene by specific sequences in the 3' untranslated region of the mRNA
    • Tsai KC, Cansino VV, Kohn DT, Neve RL, Perrone-Bizzozero NI. 1997. Post-transcriptional regulation of the GAP-43 gene by specific sequences in the 3' untranslated region of the mRNA. J Neurosci 17: 1950-1958.
    • (1997) J Neurosci , vol.17 , pp. 1950-1958
    • Tsai, K.C.1    Cansino, V.V.2    Kohn, D.T.3    Neve, R.L.4    Perrone-Bizzozero, N.I.5
  • 135
    • 80054827502 scopus 로고    scopus 로고
    • Genomic analyses of the RNA-binding protein Hu antigen R (HuR) identify a complex network of target genes and novel characteristics of its binding sites
    • Uren PJ, Burns SC, Ruan J, Singh KK, Smith AD, Penalva LO. 2011. Genomic analyses of the RNA-binding protein Hu antigen R (HuR) identify a complex network of target genes and novel characteristics of its binding sites. J Biol Chem 286: 37063-37066.
    • (2011) J Biol Chem , vol.286 , pp. 37063-37066
    • Uren, P.J.1    Burns, S.C.2    Ruan, J.3    Singh, K.K.4    Smith, A.D.5    Penalva, L.O.6
  • 136
    • 84862300109 scopus 로고    scopus 로고
    • Conservation of the RNA transport machineries and their coupling to translation control across eukaryotes
    • Vazquez-Pianzola P, Suter B. 2012. Conservation of the RNA transport machineries and their coupling to translation control across eukaryotes. Comp Funct Genomics 2012: 287852.
    • (2012) Comp Funct Genomics , vol.2012 , pp. 287852
    • Vazquez-Pianzola, P.1    Suter, B.2
  • 137
    • 0030827809 scopus 로고    scopus 로고
    • Sequential expression and role of Hu RNA-binding proteins during neurogenesis
    • Wakamatsu Y, Weston JA. 1997. Sequential expression and role of Hu RNA-binding proteins during neurogenesis. Development 124: 3449-3460.
    • (1997) Development , vol.124 , pp. 3449-3460
    • Wakamatsu, Y.1    Weston, J.A.2
  • 138
    • 0035153840 scopus 로고    scopus 로고
    • Structural basis for recognition of AUrich element RNA by the HuD protein
    • Wang X, Tanaka Hall TM. 2001. Structural basis for recognition of AUrich element RNA by the HuD protein. Nat Struct Biol 8: 141-145.
    • (2001) Nat Struct Biol , vol.8 , pp. 141-145
    • Wang, X.1    Tanaka Hall, T.M.2
  • 139
    • 77954366986 scopus 로고    scopus 로고
    • Promotion of exon 6 inclusion in HuD pre-mRNA by Hu protein family members
    • Wang H, Molfenter J, Zhu H, Lou H. 2010. Promotion of exon 6 inclusion in HuD pre-mRNA by Hu protein family members. Nucleic Acids Res 38: 3760-3770.
    • (2010) Nucleic Acids Res , vol.38 , pp. 3760-3770
    • Wang, H.1    Molfenter, J.2    Zhu, H.3    Lou, H.4
  • 140
    • 0037208077 scopus 로고    scopus 로고
    • The 3'-UTR of the mRNA coding for the major protein kinase C substrate MARCKS contains a novel CU-rich element interacting with the mRNA stabilizing factors HuD and HuR
    • Wein G, Rossler M, Klug R, Herget T. 2003. The 3'-UTR of the mRNA coding for the major protein kinase C substrate MARCKS contains a novel CU-rich element interacting with the mRNA stabilizing factors HuD and HuR. Eur J Biochem 270: 350-365.
    • (2003) Eur J Biochem , vol.270 , pp. 350-365
    • Wein, G.1    Rossler, M.2    Klug, R.3    Herget, T.4
  • 142
    • 84860320152 scopus 로고    scopus 로고
    • The regulation of mRNA stability in mammalian cells: 2.0
    • Wu X, Brewer G. 2012. The regulation of mRNA stability in mammalian cells: 2.0. Gene 500: 10-21.
    • (2012) Gene , vol.500 , pp. 10-21
    • Wu, X.1    Brewer, G.2
  • 143
    • 0027933867 scopus 로고
    • Purification and characterization of nucleolin and its identification as a transcription repressor
    • Yang TH, Tsai WH, Lee YM, Lei HY, Lai MY, Chen DS, Yeh NH, Lee SC. 1994. Purification and characterization of nucleolin and its identification as a transcription repressor. Mol Cell Biol 14: 6068-6074.
    • (1994) Mol Cell Biol , vol.14 , pp. 6068-6074
    • Yang, T.H.1    Tsai, W.H.2    Lee, Y.M.3    Lei, H.Y.4    Lai, M.Y.5    Chen, D.S.6    Yeh, N.H.7    Lee, S.C.8
  • 144
    • 0029125216 scopus 로고
    • Nucleolin and heterogeneous nuclear ribonucleoprotein C proteins specifically interact with the 3'-untranslated region of amyloid protein precursor mRNA
    • Zaidi SH, Malter JS. 1995. Nucleolin and heterogeneous nuclear ribonucleoprotein C proteins specifically interact with the 3'-untranslated region of amyloid protein precursor mRNA. J Biol Chem 270: 17292-17298.
    • (1995) J Biol Chem , vol.270 , pp. 17292-17298
    • Zaidi, S.H.1    Malter, J.S.2
  • 146
    • 0036247201 scopus 로고    scopus 로고
    • Region-specific alternative splicing in the nervous system: Implications for regulation by the RNA-binding protein NAPOR
    • ZhangW, Liu H, Han K, Grabowski PJ. 2002. Region-specific alternative splicing in the nervous system: Implications for regulation by the RNA-binding protein NAPOR. RNA 8: 671-685.
    • (2002) RNA , vol.8 , pp. 671-685
    • Zhangw Liu, H.1    Han, K.2    Grabowski, P.J.3
  • 147
    • 80052594686 scopus 로고    scopus 로고
    • Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner
    • Zhou HL, Hinman MN, Barron VA, Geng C, Zhou G, Luo G, Siegel RE, Lou H. 2011. Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner. Proc Natl Acad Sci 108: E627-E635.
    • (2011) Proc Natl Acad Sci , vol.108
    • Zhou, H.L.1    Hinman, M.N.2    Barron, V.A.3    Geng, C.4    Zhou, G.5    Luo, G.6    Siegel, R.E.7    Lou, H.8
  • 148
    • 33845380816 scopus 로고    scopus 로고
    • A nuclear function of Hu proteins as neuron-specific alternative RNA processing regulators
    • Zhu H, Hasman RA, Barron VA, Luo G, Lou H. 2006. A nuclear function of Hu proteins as neuron-specific alternative RNA processing regulators. Mol Biol Cell 17: 5105-5114.
    • (2006) Mol Biol Cell , vol.17 , pp. 5105-5114
    • Zhu, H.1    Hasman, R.A.2    Barron, V.A.3    Luo, G.4    Lou, H.5
  • 149
    • 38949098620 scopus 로고    scopus 로고
    • Regulation of neuron-specific alternative splicing of neurofibromatosis type 1 premRNA
    • Zhu H, Hinman MN, Hasman RA, Mehta P, Lou H. 2008. Regulation of neuron-specific alternative splicing of neurofibromatosis type 1 premRNA. Mol Cell Biol 28: 1240-1251.
    • (2008) Mol Cell Biol , vol.28 , pp. 1240-1251
    • Zhu, H.1    Hinman, M.N.2    Hasman, R.A.3    Mehta, P.4    Lou, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.