Intranasal infusion of melanocortin receptor four (MC4R) antagonist to rats ameliorates development of depression and anxiety related symptoms induced by single prolonged stress

Behavioural Brain Research

Volumn 250, Issue , 2013, Pages 139-147

  Serova, Lidia I ^a   Laukova, Marcela ^a   Alaluf, Lishay G ^a   Sabban, Esther L ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Anxiety; Depression; HS014; Intranasal; Melanocortin receptor four; Single prolonged stress

Indexed keywords

BETA INTERMEDIN[11-22][11 (N ACETYLCYSTEINE) 14 [3 (2 NAPHTHYL) DEXTRO ALANINE] 18 CYSTEINE 22 ASPARTIC ACID AMIDE] 11,18 CYCLIC DISULFIDE; HORMONE RECEPTOR BLOCKING AGENT; MELANOCORTIN 4 RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; CHRONIC STRESS; COMORBIDITY; CONTROLLED STUDY; DEFECATION; DEPRESSION; DOSE RESPONSE; DRUG EFFICACY; DRUG MEGADOSE; DRUG RESPONSE; FORCED SWIMMING TEST; GROOMING; IMMOBILIZATION STRESS; MALE; MAZE TEST; NONHUMAN; OPEN FIELD TEST; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; RAT;

ADMINISTRATION, INTRANASAL; ANALYSIS OF VARIANCE; ANIMALS; ANTIDEPRESSIVE AGENTS; ANXIETY; DEPRESSION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXPLORATORY BEHAVIOR; GROOMING; MALE; MAZE LEARNING; PEPTIDES, CYCLIC; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, MELANOCORTIN, TYPE 4; RESTRAINT, PHYSICAL; SWIMMING; TIME FACTORS;

EID: 84878676824     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2013.05.006     Document Type: Article

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